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Total 550 results found since Jan 2013.

Defining carotid near-occlusion with full collapse: a pooled analysis
ConclusionsDefining near-occlusion with full collapse as distal ICA diameter  ≤ 2.0 mm and/or ICA ratio ≤ 0.42 seems to yield better prognostic discrimination than the traditional appearance-based definition. This novel definition can be used in prognostic and treatment studies of near-occlusion with full collapse.
Source: Neuroradiology - May 4, 2021 Category: Radiology Source Type: research

SARS-CoV-2 Impairs Vision
Conclusions: This mini review shows that impaired vision may be the initial manifestation of COVID-19, that all sections of the visual tract may be affected and causative for visual impairment in COVID-19 patients, and that SARS-CoV-2 manifests along the visual tract with ischemia, focal infection, and immunological reactions.
Source: Journal of Neuro-Ophthalmology - June 1, 2021 Category: Opthalmology Tags: Disease of the Year: COVID-19 Source Type: research

The Frequency of Carotid Intraplaque Hemorrhage on Vessel Wall Imaging in Patients With Retinal Artery Occlusion: A Cross-Sectional Prevalence Study
Conclusions: Carotid IPH is independently associated with RAO. The use of plaque imaging in the evaluation of patients with acute RAO is therefore supported.
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Original Contribution Source Type: research

Incorporation of Retinal Arteriolosclerosis into Risk Stratification of Blood Pressure Category According to the 2017 ACC/AHA Blood Pressure Guideline
CONCLUSION: Incorporation of the assessment for RA may facilitate the CVD risk stratification of people classified based on the 2017 ACC/AHA BP guideline, particularly for those categorized in stage 1 hypertension.PMID:34866070 | DOI:10.5551/jat.63262
Source: Journal of Atherosclerosis and Thrombosis - December 6, 2021 Category: Cardiology Authors: Satoshi Matsuoka Hidehiro Kaneko Tatsuya Kamon Yuta Suzuki Yuichiro Yano Akira Okada Hidetaka Itoh Kojiro Morita Akira Fukui Katsuhito Fujiu Nobuaki Michihata Taisuke Jo Norifumi Takeda Hiroyuki Morita Sunao Nakamura Takashi Yokoo Akira Nishiyama Koichi N Source Type: research

Central retinal artery occlusion: a retrospective study of disease presentation, treatment, and outcomes
CONCLUSIONS: The majority of patients with CRAO presented to eye care providers, and few present within the potential window for thrombolysis of 4.5 hours, highlighting the need for public awareness strategies. Our cohort highlights the significant rate of systemic comorbidity that exists in these patients.PMID:35307340 | DOI:10.1016/j.jcjo.2022.02.015
Source: Canadian Journal of Ophthalmology - March 21, 2022 Category: Opthalmology Authors: Meghan J Smith Matthew D Benson Matthew Tennant Imran Jivraj Source Type: research

Retinal parameters, cortical cerebral microinfarcts and their interaction with cognitive impairment
Conclusions: Retinal vascular and neuronal parameters are associated with cortical CMIs and persons with both pathologies are likely to have cognitive impairment. Further studies may be warranted to evaluate the clinical utility of retinal parameters and CMI in risk prediction for cognitive dysfunction.Data access statement: The data that support the findings of this study is available from the corresponding author upon request.PMID:35450485 | DOI:10.1177/17474930221097737
Source: Atherosclerosis - April 22, 2022 Category: Cardiology Authors: Saima Hilal Carol Y Cheung Tien Yin Wong Leopold Schmetterer Christopher Chen Source Type: research

Loss of the heterogeneous expression of flippase ATP11B leads to cerebral small vessel disease in a normotensive rat model
AbstractCerebral small vessel disease (SVD) is the leading cause of vascular dementia, causes a quarter of strokes, and worsens stroke outcomes. The disease is characterised by patchy cerebral small vessel and white matter pathology, but the underlying mechanisms are poorly understood. This microvascular and tissue damage has been classically considered secondary to extrinsic factors, such as hypertension, but this fails to explain the patchy nature of the disease, the link to endothelial cell (EC) dysfunction even when hypertension is absent, and the increasing evidence of high heritability to SVD-related brain damage. We...
Source: Acta Neuropathologica - May 30, 2022 Category: Neurology Source Type: research