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Total 550 results found since Jan 2013.
Peptide5 attenuates rtPA related brain microvascular endothelial cells reperfusion injury via the Wnt/ β-catenin signalling pathway
CONCLUSION: This study showed that the application of peptide5 maintained cell viability and permeability associated with rtPA treatment, revealing a possible pathway that could be exploited to limit rtPA-related endothelial cell injury during ischemic stroke. Furthermore, the altered Wnt/β-catenin signaling pathway demonstrated that signaling pathways associated with Cx43 might have potential applications in the future. This study may provide a new way to attenuate HT and assist the application of rtPA in ischemic stroke.PMID:34370635 | DOI:10.2174/1567202618666210809115305
Source: Current Neurovascular Research - August 9, 2021 Category: Neurology Authors: Weimin Ren Chuyi Huang Heling Chu Yuping Tang Xiaobo Yang Source Type: research
Interrupted versus uninterrupted anticoagulation therapy for catheter ablation in adults with arrhythmias
CONCLUSIONS: This meta-analysis showed that the evidence is uncertain to inform the decision to either interrupt or continue anticoagulation therapy around CA procedure in adults with arrhythmia on outcomes of thromboembolic events, major and minor bleeding, all-cause mortality, asymptomatic thromboembolic events, and a composite endpoint of thromboembolic events (stroke, systemic embolism, major bleeding, and all-cause mortality). Most studies in the review adopted a minimal interruption strategy which has the advantage of reducing the risk of bleeding while maintaining a lower level of anticoagulation to prevent periproc...
Source: Cochrane Database of Systematic Reviews - October 21, 2021 Category: General Medicine Authors: Ghada A Bawazeer Hadeel A Alkofide Aya A Alsharafi Nada O Babakr Arwa M Altorkistani Tarek S Kashour Michael Miligkos Khalid M AlFaleh Lubna A Al-Ansary Source Type: research
Mild Hypertensive Retinopathy and Risk of Cardiovascular Disease: The Suita Study
CONCLUSION: Mild hypertensive retinopathy was positively associated with CVD and stroke risk in the urban Japanese population. Especially, generalized arteriolar narrowing and enhanced arteriolar wall reflex were positively associated with CVD risk. These findings suggested that retinal photography could be helpful for cardiovascular risk stratification in the primary cardiovascular prevention.PMID:35034920 | DOI:10.5551/jat.63317
Source: Journal of Atherosclerosis and Thrombosis - January 17, 2022 Category: Cardiology Authors: Jiaqi Li Yoshihiro Kokubo Ahmed Arafa Haytham A Sheerah Makoto Watanabe Yoko M Nakao Kyoko Honda-Kohmo Rena Kashima Yukie Sakai Emi Watanabe Masayuki Teramoto Tomoharu Dohi Masatoshi Koga Source Type: research
The impact of initial admission department on the management and prognosis of retinal artery occlusion
CONCLUSIONS: The study demonstrated that the visual prognosis of RAO was devastating regardless of the neurology and ophthalmology department. Given the admission delay, inadequate management, and high risk of cardiovascular risk factors and stroke, stroke centers should be recommended as initial admission departments for RAO patients.PMID:36305143 | DOI:10.2174/1567202620666221027091249
Source: Current Neurovascular Research - October 28, 2022 Category: Neurology Authors: Yanqin Liu Shuju Dong Yaxi Luo Yanbo Li Changling Li Dong Zhou Li He Source Type: research
