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MassDevice.com +5 | The top 5 medtech stories for May 26, 2016
Say hello to MassDevice +5, a bite-sized view of the top five medtech stories of the day. This feature of MassDevice.com’s coverage highlights our 5 biggest and most influential stories from the day’s news to make sure you’re up to date on the headlines that continue to shape the medical device industry. Get this in your inbox everyday by subscribing to our newsletters.   5. Ortho Kinematics wins Health Canada nod for VMA system Ortho Kinematics said today it won Health Canada authorization for its Vertebral Motion Analysis spinal imaging system. The VMA system from Austin, Texas-based Ortho Kinema...
Source: Mass Device - May 26, 2016 Category: Medical Equipment Authors: MassDevice Tags: Blog Plus 5 Source Type: news

Diabetes impairs spatial learning and memory and hippocampal neurogenesis via BDNF in rats with transient global ischemia.
Abstract Diabetic conditions worsen the prognosis of stroke. The molecular mechanism underlying the impairment of post-stroke recovery is not very clear. Here, we establish a rat model resembling human cerebral infarction with or without diabetes to determine how diabetes impairs cognitive recovery. Our data show that diabetes inhibits hippocampal BDNF expression and impairs the survival and differentiation of the newborn neural cells in rats with ischemia. Consequently, the rats of diabetic ischemia have a significantly lower score in spatial learning and memory in the Morris water maze test than the non-diabetic...
Source: Brain Research Bulletin - May 23, 2016 Category: Neurology Authors: Han H, Wu LM, Han MX, Yang WM, Wang YX, Fang ZH Tags: Brain Res Bull Source Type: research

The 8 Bad Eating Habits You Need to Break in Your 20s
We all know how it goes. You're away from home for the first time. You're completely in charge of your own meals. Mom and Dad always said you couldn't have cake and Cocoa Puffs for dinner? Well now you can have the whole cake and no one is there to say a word. Eventually, though, your body is not going to like all that damage. Learn how to end those bad habits now, so your future self won't want to come back to punch you in the face. 1. Eating dinner at midnight Eating a late dinner can screw up your body's natural cycles. It can interfere with your sleep schedule, for one thing, but it might also be the reason that y...
Source: Healthy Living - The Huffington Post - July 18, 2016 Category: Consumer Health News Source Type: news

September Is Childhood Obesity Month -- Get The Facts
The obesity epidemic continues to dominate headlines--and for good reason. Obesity is a leading cause of heart disease, diabetes, high blood pressure, and stroke. Many of these conditions occur in adults but often begin in childhood. This September is National Childhood Obesity Awareness Month. By knowing the facts and taking steps to help your children live a healthier lifestyle, childhood obesity and its resulting complications may be prevented. The Facts According to the Centers for Disease Control & Prevention (CDC), one in three children in the U.S. is overweight or obese. Childhood obesity doubled in children and ...
Source: Healthy Living - The Huffington Post - September 28, 2016 Category: Consumer Health News Source Type: news

Patient, Doctor, and the Data: Emergence of the Third Player
Amith Vikramr The conventional model of medicine had only two players. The doctor alone had access to all medical information and his encounter with the patient was the only way to obtain health-related information. The dawn of the information age led to a change in the dynamics in this relationship. A consumerist model of healthcare has emerged where doctors partner with patients in managing the patient’s illness. The advances in systems biology, big data and consumer health care electronics will add patient data as a new element to the patient-physician interface. In the next decade, individual patients will generate ...
Source: Society for Participatory Medicine - December 6, 2016 Category: Journals (General) Authors: Nanette Mattox Tags: Newsletter e-patient movement empowered patient Moral Injury participatory medicine Patient Participation Source Type: news

7 medtech stories we missed this week: June 2, 2017
[Photo from unsplash.com]From Implandata receiving CE Marking to Inolife eyeing up-listing, here are 7 medtech stories we missed this week but thought were still worth mentioning. 1. Dextera seeks expanded indications for MicroCutter 5/80 stapler Dextera Surgical announced in a June 1 press release that it has filed a 510(k) with the FDA for its MicroCutter 5/80 stapler. The company wants to expand the indications of the MicroCutter 5/80 for use in liver, pancreas, kidney and spleen surgeries. Currently, the staplers are used for transection and resection in multiple open minimally-invasive urologic, thoracic and pediatr...
Source: Mass Device - June 2, 2017 Category: Medical Devices Authors: Danielle Kirsh Tags: Business/Financial News Clinical Trials News Well Regulatory/Compliance Research & Development c2 Therapeutics Dextera Surgical DreaMed Diabetes EndoGastric Solutions Inc. Implandata Inolife MicroTransponder Inc. Source Type: news

Patient, Doctor, and the Data: Emergence of the Third Player
The conventional model of medicine had only two players. The doctor alone had access to all medical information and his encounter with the patient was the only way to obtain health-related information. The dawn of the information age led to a change in the dynamics in this relationship. A consumerist model of healthcare has emerged where doctors partner with patients in managing the patient’s illness. The advances in systems biology, big data and consumer health care electronics will add patient data as a new element to the patient-physician interface. In the next decade, individual patients will generate billions of da...
Source: Society for Participatory Medicine - December 6, 2016 Category: General Medicine Authors: Nanette Mattox Tags: Newsletter e-patient movement empowered patient Moral Injury participatory medicine Patient Participation Source Type: news

Sleep biology discovery could lead to new insomnia treatments that don ’t target the brain
UCLA scientists report the first evidence that a gene outside the brain controls the ability to rebound from sleep deprivation — a surprising discovery that could eventually lead to greatly improved treatments for insomnia and other sleep disorders that do not involve getting a drug into the brain.The scientists report that increasing the level of Bmal1 — a critical master gene that regulates sleep patterns — in skeletal muscle makes mice resistant to sleep deprivation.“When we first saw the importance of the muscle, we were surprised,” said senior author Ketema Paul, UCLA associate professor of integrative biolo...
Source: UCLA Newsroom: Health Sciences - August 10, 2017 Category: Universities & Medical Training Source Type: news

Development and validation of Risk Equations for Complications Of type 2 Diabetes (RECODe) using individual participant data from randomised trials
Publication date: Available online 10 August 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Sanjay Basu, Jeremy B Sussman, Seth A Berkowitz, Rodney A Hayward, John S Yudkin Background In view of substantial mis-estimation of risks of diabetes complications using existing equations, we sought to develop updated Risk Equations for Complications Of type 2 Diabetes (RECODe). Methods To develop and validate these risk equations, we used data from the Action to Control Cardiovascular Risk in Diabetes study (ACCORD, n=9635; 2001–09) and validated the equations for microvascular events using data from the Di...
Source: The Lancet Diabetes and Endocrinology - August 11, 2017 Category: Endocrinology Source Type: research

Spacing out after staying up late? Here ’s why
Ever sleep poorly and then walk out of the house without your keys? Or space out while driving to work and nearly hit a stalled car?A new study led by UCLA ’sDr. Itzhak Fried is the first to reveal how sleep deprivation disrupts brain cells ’ ability to communicate with each other. Fried and his colleagues believe that disruption leads to temporary mental lapses that affect memory and visual perception. Their findings are published online today by Nature Medicine.“We discovered that starving the body of sleep also robs neurons of the ability to function properly,” said Fried, the study’s senior author, a profess...
Source: UCLA Newsroom: Health Sciences - November 6, 2017 Category: Universities & Medical Training Source Type: news

Neuroimaging and Neurolaw: Drawing the Future of Aging
Vincenzo Tigano1, Giuseppe Lucio Cascini2, Cristina Sanchez-Castañeda3, Patrice Péran4 and Umberto Sabatini5* 1Department of Juridical, Historical, Economic and Social Sciences, University of Magna Graecia, Catanzaro, Italy 2Department of Experimental and Clinical Medicine, University of Magna Graecia, Catanzaro, Italy 3Department of Clinical Psychology and Psychobiology, University of Barcelona, Barcelona, Spain 4ToNIC, Toulouse NeuroImaging Center, Université de Toulouse, Inserm, UPS, Toulouse, France 5Department of Medical and Surgical Sciences, University of Magna Graecia, Catanzaro, ...
Source: Frontiers in Endocrinology - April 7, 2019 Category: Endocrinology Source Type: research

A Novel Deep Neural Network Model for Multi-Label Chronic Disease Prediction
Conclusions concludes this work along with future work. Dataset and Data Preprocessing In the work, we mainly focus on multiple chronic disease classification. It can be formulated into a multi-label classification problem. There are three common chronic diseases are selected from the physical examination records: hypertension (H), diabetes (D), and fatty liver (FL). In the experiments, the physical examination datasets are collected from a local medical center, which contain 110,300 physical examination records from about 80,000 anonymous patients (Li et al., 2017a,b). Sixty-two feature items are selected from over 100...
Source: Frontiers in Genetics - April 23, 2019 Category: Genetics & Stem Cells Source Type: research

Iron Metabolism and Brain Development in Premature Infants
Yafeng Wang1,2,3, Yanan Wu2, Tao Li1,2,3, Xiaoyang Wang2,4 and Changlian Zhu2,3* 1Department of Neonatology (NICU), Children’s Hospital Affiliated Zhengzhou University, Zhengzhou, China 2Henan Key Laboratory of Child Brain Injury, Institute of Neuroscience and Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China 3Department of Clinical Neuroscience, Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden 4Department of Physiology, Sahlgrenska Academy, Institute of Neuroscience and Physiology, University of Got...
Source: Frontiers in Physiology - April 24, 2019 Category: Physiology Source Type: research

Preventable Cases of Oral Anticoagulant-Induced Bleeding: Data From the Spontaneous Reporting System
Conclusion: Our findings describe the most reported risk factors for preventability of oral anticoagulant-induced bleedings. These factors may be useful for targeting interventions to improve pharmacovigilance activities in our regional territory and to reduce the burden of medication errors and inappropriate prescription. Introduction Oral anticoagulant therapy is widely used for the prevention of stroke and systemic embolism in patients with atrial fibrillation, or for the prevention and treatment of deep vein thrombosis and pulmonary embolism (Raj et al., 1994; Monaco et al., 2017). Oral anticoagulants can be di...
Source: Frontiers in Pharmacology - April 29, 2019 Category: Drugs & Pharmacology Source Type: research

What Causes Facial Nerve Palsy?
Discussion Facial nerve palsy has been known for centuries, but in 1821 unilateral facial nerve paralysis was described by Sir Charles Bell. Bell’s palsy (BP) is a unilateral, acute facial paralysis that is clinically diagnosed after other etiologies have been excluded by appropriate history, physical examination and/or laboratory testing or imaging. Symptoms include abnormal movement of facial nerve. It can be associated with changes in facial sensation, hearing, taste or excessive tearing. The right and left sides are equally affected but bilateral BP is rare (0.3%). Paralysis can be complete or incomplete at prese...
Source: PediatricEducation.org - June 3, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news