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Australian guideline developers join forces to advance Living Evidence
This news item was orginally posted on Cochrane Australia website.A new report published heralds an exciting development for evidence-based health care in Australia, with the promise of near real-time incorporation of research into evidence-based guideline recommendations now a step closer to reality. TheLiving Evidence for Australian Health Care report details the outcomes of forum hosted byCochrane Australia last month  which brought together leading experts in evidence synthesis and guideline development across several of Australia’s most pressing chronic diseases to explore opportunities for advancing ‘Livi...
Source: Cochrane News and Events - June 11, 2018 Category: Information Technology Authors: Muriah Umoquit Source Type: news

Could 2018 Really Be the Year of AI in Medtech?
Has there really been another topic in medtech this year that has generated more attention than Artificial Intelligence? There have been numerous approvals, clearances, and even in some cases praise from regulatory bodies about AI-based medtech. MD+DI has been on the frontlines covering the recent AI boom. That coverage spawned a webinar titled, How Artificial Intelligence Has Changed Everything for Medtech hosted by Dave Saunders CTO and Co-founder of Galen Robotics. In just a few short weeks at MD&M Minneapolis, AI will be discussed in depth at a session titled, Artificial Intelligence (AI): What You Need to Know to ...
Source: MDDI - October 9, 2018 Category: Medical Devices Authors: Omar Ford Tags: Business Digital Health Source Type: news

The kynurenine pathway and cognitive performance in community-dwelling older adults. The Hordaland Health Study
ConclusionHigher KTR and neopterin levels, biomarkers of cellular immune activation, were associated with reduced cognitive performance, implying an association between the innate immune system, memory, and language.
Source: Brain, Behavior, and Immunity - October 25, 2018 Category: Neurology Source Type: research

Should You Take Aspirin Every Day? Here ’s What the Science Says
Aspirin is best known as an over-the-counter painkiller. But acetylsalicylic acid, as it’s called chemically, has many other health benefits, as well as side effects, in the body that have only become clear in recent years. Here’s what the latest science says about the health benefits and side effects of aspirin, as well as which conditions it may treat and those it doesn’t appear to improve. (If you are taking aspirin for any reason other than for periodic pain relief, it’s best to consult with your doctor to confirm whether the benefits outweigh the risks in your particular case.) How aspirin affe...
Source: TIME: Health - November 8, 2018 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized Drugs healthytime Source Type: news

10 New Year ’s Resolutions Doctors Actually Want You to Make
Each year, Americans’ most popular New Year’s resolutions are more or less the same: get healthy, get organized, save money. But doctors at the American Medical Association (AMA) have some more specific thoughts in mind for 2019. The AMA this week released a list of 10 wellness-focused resolutions that could “help Americans make the most impactful, long-lasting improvements to their health in 2019.” Here’s what they are — and how to make them happen. Learn your risk for type 2 diabetes Diabetes is one of the most common chronic health conditions in the U.S., affecting an estimated 30 mil...
Source: TIME: Health - December 21, 2018 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized healthytime Holidays 2018 public health Source Type: news

10 New Year's Resolutions Doctors Actually Want You to Make
Each year, Americans’ most popular New Year’s resolutions are more or less the same: get healthy, get organized, save money. But doctors at the American Medical Association (AMA) have some more specific thoughts in mind for 2019. The AMA this week released a list of 10 wellness-focused resolutions that could “help Americans make the most impactful, long-lasting improvements to their health in 2019.” Here’s what they are — and how to make them happen. Learn your risk for type 2 diabetes Diabetes is one of the most common chronic health conditions in the U.S., affecting an estimated 30 mil...
Source: TIME: Health - December 21, 2018 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized healthytime Holidays 2018 public health Source Type: news

Superbugs, Anti-Vaxxers Make WHO ’ s List Of 10 Global Health Threats
(CNN) — From climate change to superbugs, the World Health Organization has laid out 10 big threats to our global health in 2019. And unless these threats get addressed, millions of lives will be in jeopardy. Here’s a snapshot of 10 urgent health issues, according to the United Nations’ public health agency: Not vaccinating when you can One of the most controversial recent health topics in the US is now an international concern. “Vaccine hesitancy — the reluctance or refusal to vaccinate despite the availability of vaccines — threatens to reverse progress made in tackling vaccine-prevent...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 21, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Local TV Source Type: news

Relative Prognostic Importance and Optimal Levels of Risk Factors for Mortality and Cardiovascular Outcomes in Type 1 Diabetes.
CONCLUSIONS: Glycated hemoglobin, albuminuria, duration of diabetes, systolic blood pressure and low-density lipoprotein cholesterol appear the most important predictors for mortality and cardiovascular outcomes in patients with type 1 diabetes. Lower levels for glycated hemoglobin, systolic blood pressure and low-density lipoprotein cholesterol than contemporary guideline target levels appear to be associated with significantly lower risk for outcomes. PMID: 30798638 [PubMed - as supplied by publisher]
Source: Circulation - February 25, 2019 Category: Cardiology Authors: Rawshani A, Rawshani A, Sattar N, Franzén S, McGuire DK, Eliasson B, Svensson AM, Zethelius B, Miftaraj M, Rosengren A, Gudbjörnsdottir S Tags: Circulation Source Type: research

Using wearable devices in clinical trials
Brandy Chittester, chief of clinical operations, IMARC Globally, more than 325 million people own wearable, connected devices, and more than 2.5 billion own smartphones. Using wearable devices in clinical trials can bring huge benefits, however, there are also concerns. Here’s a look at how researchers are using wearable devices — and what you should consider before using them in your own research. How wearable devices are advancing medicine Right now, ClinicalTrials.gov, a global database of clinical trials, lists nearly 200 trials with “wearable devices” or “wearable technology” in the description. This in...
Source: Mass Device - March 12, 2019 Category: Medical Devices Authors: Danielle Kirsh Tags: Blog IMARC Source Type: news

Light-Induced Pupillary Responses in Alzheimer's Disease
Light-Induced Pupillary Responses in Alzheimer's Disease Pratik S. Chougule1, Raymond P. Najjar1,2, Maxwell T. Finkelstein1, Nagaendran Kandiah3,4 and Dan Milea1,2,5* 1Department of Visual Neurosciences, Singapore Eye Research Institute, Singapore, Singapore 2The Ophthalmology & Visual Sciences ACP, Duke-National University of Singapore (NUS) Medical School, Singapore, Singapore 3Department of Neurology, National Neuroscience Institute, Singapore, Singapore 4Duke-National University of Singapore (NUS), Singapore, Singapore 5Singapore National Eye Centre, Singapore, Singapore The impact of Alzhe...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

The Promoter Regions of Intellectual Disability-Associated Genes Are Uniquely Enriched in LTR Sequences of the MER41 Primate-Specific Endogenous Retrovirus: An Evolutionary Connection Between Immunity and Cognition
Discussion We have found that, in the human genome, the promoter regions of ID-associated genes are uniquely enriched in MER41 LTRs. More specifically, nine ID-associated genes that are putatively important in cognitive evolution exhibit MER41 LTRs in their promoter regions. As more than 100 families of HERV are integrated into our genome, it was important to determine whether our findings are specific to MER41 and to ID-associated genes, and if so to what extent. Among the 133 families of HERV explored here, MER41 is the only family whose LTRs were found with statistically high frequency in the promoter regions of ID-ass...
Source: Frontiers in Genetics - April 11, 2019 Category: Genetics & Stem Cells Source Type: research

Dynamic Office Environments Improve Brain Activity and Attentional Performance Mediated by Increased Motor Activity
Conclusion The results of the present study reveal short- and mid-term effects on attentional and vigilance performance, and EEG brain activity when working in a dynamic versus a static environment. During working in a dynamic office, attentional and vigilance performance increased compared to working in a static office. Brain activities show increased alpha, beta and gamma power in the frontal and central areas in the attentional task with increased theta, alpha, and beta activity in the vigilance task. These findings suggest that working in a dynamic office environment stimulates the brain towards an optimum psychophysi...
Source: Frontiers in Human Neuroscience - April 11, 2019 Category: Neuroscience Source Type: research

Multimodal Optical Diagnostics of the Microhaemodynamics in Upper and Lower Limbs
Conclusion The use of optical non-invasive diagnostic methods has a great potential for the detection of concomitant microcirculation disorders in patients with rheumatic diseases and diabetes. In this review, it was shown that the use of laser Doppler flowmetry, optical tissue oximetry and fluorescence spectroscopy together or separately may have important diagnostic value for the detection of violations, assessment of their severity, as well as for the analysis of the effectiveness of the therapy. The joint application of the considered technologies with the methods of machine learning (discriminant analysis) can be use...
Source: Frontiers in Physiology - April 15, 2019 Category: Physiology Source Type: research

10 Biggest Myths About Sleeping, According To Researchers
(CNN) — Hey, sleepyheads. What you believe about sleep may be nothing but a pipe dream. Many of us have notions about sleep that have little basis in fact and may even be harmful to our health, according to researchers at NYU Langone Health’s School of Medicine, who conducted a study published Tuesday in the journal Sleep Health. “There’s such a link between good sleep and our waking success,” said lead study investigator Rebecca Robbins, a postdoctoral research fellow in the Department of Population Health at NYU Langone Health. “And yet we often find ourselves debunking myths, whether ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - April 16, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health Healthwatch News CNN Sleep Source Type: news

Sensory Re-weighting for Postural Control in Parkinson ’s Disease
In this study, we focused primarily on the change of sensory weighting parameters when sensory conditions change. We also tested the additional hypothesis that levodopa medication would improve sensory weighting for postural control. Materials and Methods Subjects The Institutional Review Board at Oregon Health and Science University (OHSU) approved the protocol for this experiment, and all subjects gave informed consent prior to participating. Eight subjects with PD (three female) and eight healthy, age-matched controls (two female) were recruited from the Balance Disorders Laboratory database and the Parkinson’...
Source: Frontiers in Human Neuroscience - April 16, 2019 Category: Neuroscience Source Type: research