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Total 3873 results found since Jan 2013.
Impact of risk factors for recurrence after the first ischemic stroke in adults: A systematic review and meta-analysis
Publication date: Available online 16 October 2018Source: Journal of Clinical NeuroscienceAuthor(s): Shengbang Zheng, Baodong YaoAbstractRisk factors for first-ever stroke have been studied extensively, while those for recurrent stroke are not accurately understood. To provide the adequate secondary prevention for the patients, it is necessary to reveal the risk factors that dominate recurrent stroke. Multiple databases were adopted to search for the relevant studies and full-text articles involving in the risk factors for stroke recurrence were reviewed. Meta-analyses were performed with Review Manager 5.0 to estimate the...
Source: Journal of Clinical Neuroscience - October 17, 2018 Category: Neuroscience Source Type: research
Fluid and energy intake in stroke patients during acute hospitalization in a stroke unit
Publication date: Available online 14 January 2019Source: Journal of Clinical NeuroscienceAuthor(s): Alex Buoite Stella, Marina Gaio, Giovanni Furlanis, Pauline Douglas, Marcello Naccarato, Paolo ManganottiAbstractProper hydration and nutrition have been found to be contributing factors to a better recovery in patients after stroke. A better knowledge of factors influencing fluid and energy intake may contribute to a better care of the acute stroke patient. Aim of this study was to describe hydration status, fluid intake, and energy intake of stroke patients during acute hospitalization in a stroke unit. A retrospective de...
Source: Journal of Clinical Neuroscience - January 15, 2019 Category: Neuroscience Source Type: research
Mineralizing angiopathy with basal ganglia stroke after minor trauma: Case series including two familial cases
Conclusion: Most common cause for acute basal ganglia stroke in toddlers was mineralizing angiopathy of lenticulostriate vessels. It was preceded by minor trauma in most cases.
Source: Journal of Pediatric Neurosciences - February 25, 2019 Category: Neuroscience Authors: Vykuntaraju K Gowda Vidya Manjeri Varunvenkat M Srinivasan Sushma V Sajjan Asha Benakappa Source Type: research
The Impact of Physical Activity Before and After Stroke on Stroke Risk and Recovery: a Narrative Review
AbstractPurpose of the ReviewSummarising the evidence for pre- and post-stroke physical activity (PA) and exercise to reduce stroke risk, and improve recovery and brain health.Recent FindingsPre-stroke PA reduces the risk of stroke, and post-stroke PA and exercise reduce cardiovascular risk factors, which can moderate the risk of recurrent strokes. Pre-clinical evidence indicates that exercise enhances neuroplasticity. The results from clinical studies showed that exercise changes brain activity patterns in stroke survivors, which can be a signal neuroplasticity. The intensity of pre- and post-stroke PA and exercise is a k...
Source: Current Neurology and Neuroscience Reports - April 21, 2019 Category: Neuroscience Source Type: research
When does spasticity in the upper limb develop after a first stroke? A nationwide observational study on 861 stroke patients
This study investigated the time taken for upper extremity spasticity to develop and its regional difference after first-ever stroke onset in a nationwide multicenter study in South Korea. The retrospective observational study included 861 individuals with post-stroke spasticity in the upper limbs. Spasticity in the upper extremity joints was defined as a modified Ashworth Scale score ≥1. The median time to develop upper limb spasticity after stroke onset was 34 days. 12% of post-stroke spasticity cases developed between 2 months and 3 months and 13% developed after 3 months from onset. At the time of diagnosis o...
Source: Journal of Clinical Neuroscience - May 12, 2019 Category: Neuroscience Source Type: research
Temporal Features of Muscle Synergies in Sit-to-Stand Motion Reflect the Motor Impairment of Post-Stroke Patients
Sit-to-stand (STS) motion is an important daily activity, and many post-stroke patients have difficulty performing STS motion. Previous studies found that there are four muscle synergies (synchronized muscle activations) in the STS motion of healthy adults. However, for post-stroke patients, it is unclear whether muscle synergies change and which features primarily reflect motor impairment. Here, we use a machine learning method to demonstrate that temporal features in two muscle synergies that contribute to hip rising and balance maintenance motion reflect the motor impairment of post-stroke patients. Analyzing the muscle...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - September 30, 2019 Category: Neuroscience Source Type: research
Circulating Aquaporin-4 as a biomarker of early neurological improvement in stroke patients: a pilot study
Publication date: Available online 28 October 2019Source: Neuroscience LettersAuthor(s): Laura Ramiro, Alba Simats, Anna Penalba, Alvaro Garcia-Tornel, Alex Rovira, Fernando Mancha, Alejandro Bustamante, Joan MontanerAbstractPatients’ outcome prediction after ischemic stroke is still challenging. Aquaporin-4 (AQP4) is a water channel that is up-regulated in the brain after the ischemic event, but its presence in bloodstream of stroke patients has not been previously studied. The aim of this pilot study was to investigate circulating AQP4 levels after stroke and its correlation with infarct growth and neurological outcome...
Source: Neuroscience Letters - October 30, 2019 Category: Neuroscience Source Type: research
Association Between the Change of Serum Copper and Ischemic Stroke: a Systematic Review and Meta-Analysis
AbstractIschemic stroke is the most common stroke subtypes with all strokes. More and more studies found that serum copper was related to the ischemic stroke. However, the correlation between serum copper and ischemic stroke was inconsistent. We performed the meta-analysis to assess the association between the change of serum copper and ischemic stroke. Electronic databases were identified to search for relevant studies about serum copper and ischemic stroke from inception to February 28, 2019. Eight studies with a total of 777 participants were included into this meta-analysis. Because of high heterogeneity (I2 = 71%), we...
Source: Journal of Molecular Neuroscience - November 27, 2019 Category: Neuroscience Source Type: research
Cerebral collaterals and stroke in patients with isolated carotid artery dissections
Publication date: Available online 11 January 2020Source: Journal of Clinical NeuroscienceAuthor(s): Ching-Jen Chen, Ilana E. Green, Bradford B. Worrall, Andrew M. SoutherlandAbstractTo investigate potential association between collateral arterial supply and stroke in patients with isolated internal carotid artery dissection (iCeAD). We hypothesized a lower risk of stroke in patients with more robust collateral supply. This is a single-center, retrospective review of iCeAD patients between 1994 and 2018. iCeAD patients with sufficient neuroimaging data were included. Patients were categorized based on cerebral infarction (...
Source: Journal of Clinical Neuroscience - January 13, 2020 Category: Neuroscience Source Type: research
Impact of a Structured Response and Evidence-Based Checklist on In-hospital Stroke Outcomes
CONCLUSIONS
Use of a checklist during inpatient stroke events can potentially increase adherence to guidelines for appropriate treatment and reduce mortality. Hospital response teams should consider use of a structured response system with an evidence-based checklist for high-acuity, low-frequency events such as in-hospital stroke.
Source: Journal of Neuroscience Nursing - April 29, 2020 Category: Neuroscience Tags: Article Source Type: research
HDAC2 (Histone deacetylase 2): a critical factor in environmental enrichment ‐mediated stroke recovery
In this study, focal stroke was induced by photothrombosis in male mice exposing to EE or standard housing (SH) conditions. Recombinant virus vectors, including Ad‐HDAC2‐Flag, AAV‐CAG‐EGFP‐Cre, LV‐shHDAC2 or their controls were microinjected into the motor co rtex at 3 d before stroke. Grid‐walking and cylinder tasks were conducted to assess motor function. Western blot and immunostaining were used to uncover the mechanisms underlying EE‐mediated stroke recovery. We found that EE exposure reversed stroke‐induced HDAC2 upregulation, implicating HDAC 2 in EE‐mediated functional recovery. Importantly, EE...
Source: Journal of Neurochemistry - May 15, 2020 Category: Neuroscience Authors: Yu ‐Hui Lin,
Meng‐Cheng Yao,
Hai‐Yin Wu,
Jian Dong,
Huan‐Yu Ni,
Xiao‐Lin Kou,
Lei Chang,
Chun‐Xia Luo,
Dong‐Ya Zhu Tags: ORIGINAL ARTICLE Source Type: research
Relations between knee and ankle muscle coactivation and temporospatial gait measures in patients without hypertonia early after stroke.
Abstract
It is unclear whether muscle coactivation during gait is altered early after stroke and among which muscles. We sought to characterize muscle coactivation during gait in subacute stroke subjects without hypertonia and explore the relationship with temporospatial parameters. In 70 stroke (23 ± 12 days post-onset) and 29 age-matched healthy subjects, surface electromyography signals were used to calculate coactivation magnitude and duration between rectus femoris and medial hamstring (knee antagonistic coactivation), tibialis anterior and medial gastrocnemius (ankle antagonistic coactivation), and rec...
Source: Experimental Brain Research - October 15, 2020 Category: Neuroscience Authors: Chow JW, Stokic DS Tags: Exp Brain Res Source Type: research
Post-Stroke Working Memory Dysfunction: A Meta-Analysis and Systematic Review
AbstractThis review investigates the severity and nature of post-stroke working memory deficits with reference to the multi-component model of working memory. We conducted a systematic search in PubMed up to March 2019 with search terms for stroke and memory. Studies on adult stroke patients, that included a control group, and assessed working memory function, were selected. Effect sizes (Hedges ’g) were extracted from 50 studies (in total 3,084 stroke patients) based on the sample size, mean and standard deviation of patients and controls. Performance of stroke patients was compared to healthy controls on low-load (i.e....
Source: Neuropsychology Review - November 24, 2020 Category: Neuroscience Source Type: research
Biphasic roles of pentraxin 3 in cerebrovascular function after white matter stroke.
Abstract
Recent clinical studies suggest that pentraxin 3 (PTX3), which is known as an acute-phase protein that is produced rapidly at local sites of inflammation, may be a new biomarker of disease risk for central nervous system disorders, including stroke. However, the effects of PTX3 on cerebrovascular function in the neurovascular unit (NVU) after stroke are mostly unknown, and the basic research regarding the roles of PTX3 in NVU function is still limited. In this reverse translational study, we prepared mouse models of white matter stroke by vasoconstrictor (ET-1 or L-Nio) injection into the corpus callosum ...
Source: CNS Neuroscience and Therapeutics - December 11, 2020 Category: Neuroscience Authors: Shindo A, Takase H, Hamanaka G, Chung KK, Mandeville ET, Egawa N, Maki T, Borlongan M, Takahashi R, Lok J, Tomimoto H, Lo EH, Arai K Tags: CNS Neurosci Ther Source Type: research
Gender Difference in the Association Between Stroke Knowledge and Health Behavior Before the Onset of Stroke Among Chinese Hypertensive Patients
BACKGROUND: Previous research has shown that men and women have different levels of stroke knowledge and differing health behaviors, which are important factors affecting blood pressure, as hypertension is a key risk factor for stroke occurrence. There has been little research on the effects of sex on the association between these 2 variables before the onset of stroke among Chinese hypertensive patients. METHODS: A cross-sectional study and a convenience sampling method were used. 272 male and 118 female hypertensive stroke patients were recruited. Each patient completed the Stroke Knowledge Questionnaire and the Health B...
Source: Journal of Neuroscience Nursing - July 9, 2021 Category: Neuroscience Tags: Articles Source Type: research
