James Goodrich: A personal tribute
Sandip ChatterjeeJournal of Pediatric Neurosciences 2020 15(2):166-167 (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - June 30, 2020 Category: Neuroscience Authors: Sandip Chatterjee Source Type: research

Autism spectrum disorder and mammalian target of rapamycin system
Annio Posar, Paola ViscontiJournal of Pediatric Neurosciences 2020 15(2):164-165 (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - June 30, 2020 Category: Neuroscience Authors: Annio Posar Paola Visconti Source Type: research

West syndrome and neurocutaneous syndromes: A never-ending association
Singanamalla Bhanudeep, Priyanka Madaan, Niteesh Bharadwaj, Lokesh Saini, Dipankar DeJournal of Pediatric Neurosciences 2020 15(2):162-163 (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - June 30, 2020 Category: Neuroscience Authors: Singanamalla Bhanudeep Priyanka Madaan Niteesh Bharadwaj Lokesh Saini Dipankar De Source Type: research

Amniotic band syndrome with placenta & #8211;encephalocele adhesion: An uncommon case
Aldo Jose Ferreira da SilvaJournal of Pediatric Neurosciences 2020 15(2):160-161Amniotic band syndrome is a rare condition that is associated with various malformations. Its etiology is controversial. The neuroimage shown here is of a newborn with placenta–encephalocele adhesion and other malformations that suggest amniotic band syndrome. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - June 30, 2020 Category: Neuroscience Authors: Aldo Jose Ferreira da Silva Source Type: research

A rare case report of Guillain & #8211;Barr & #233; syndrome presenting as unilateral facial palsy with isolated acute bulbar palsy
Prachi Yadav, Sahil Dhaka, Richa Chaudhary, Sachin Damke, Sham LohiyaJournal of Pediatric Neurosciences 2020 15(2):157-159Guillain–Barré syndrome (GBS) is an immune-mediated acute inflammatory polyradiculoneuropathy and it is the most common cause of acute flaccid paralysis worldwide. There are some rare variants of GBS, which may be easily missed unless suspected. Here we present a case of GBS presenting as isolated acute bulbar palsy. A 10-month-old infant, known case of tricuspid atresia with pulmonary stenosis, presented with left-sided lower motor neuron type of facial palsy and palsy of bilateral glossopha...
Source: Journal of Pediatric Neurosciences - June 30, 2020 Category: Neuroscience Authors: Prachi Yadav Sahil Dhaka Richa Chaudhary Sachin Damke Sham Lohiya Source Type: research

A rare case of peripheral nerve hyperexcitability in childhood: Isaacs syndrome
We present a 13-year-old girl with muscle stiffness and neuromyotonia diagnosed Isaac syndrome with spontaneous discharge potentials on motor unit in electromyography and the diagnosis supported by the presence of antinuclear antibodies. A successful treatment was obtained using low-dose carbamazepine. Cause of Isaacs syndrome is unknown, generally thought to be an autoimmune etiology with voltage-gated potassium channelopathy; it sometimes occurs as a paraneoplastic syndrome. Early use of electromyography has critical role in the differential diagnosis with certain muscle disorders and peripheral nerve hyperexcitability s...
Source: Journal of Pediatric Neurosciences - June 30, 2020 Category: Neuroscience Authors: Seda Kanmaz Muhittin Ozcan Erdem Simsek Hepsen M Serin Ibrahim Aydogdu Sarenur Gokben Hasan Tekgul Source Type: research

Cerebral venous sinus thrombosis following primary varicella infection in a child
Leema P Cornelius, Vivekasaravanan Raju, Asir J PaulrajJournal of Pediatric Neurosciences 2020 15(2):150-152Varicella infection commonly called chicken pox is a benign self-limiting infection in children. Neurological complications following varicella infection are rare. Cerebral venous sinus thrombosis following varicella infection is very rare. Herewith we report a child who developed transverse and sigmoid sinus thrombosis following chicken pox. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - June 30, 2020 Category: Neuroscience Authors: Leema P Cornelius Vivekasaravanan Raju Asir J Paulraj Source Type: research

A rare case of intramedullary lipoma of brainstem to thoracic cord & #8211; & #8211;What to do ?
Conclusion: Such lipoma needs extensive pre-, intra-, and postoperative planning. The goal should be decompression, rather than excision. Outcome is good with partial resection. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - June 30, 2020 Category: Neuroscience Authors: Ishu Bishnoi Pardaman Singh Geetika Duggal Sunil Sorout Source Type: research

Delayed diagnosis of cobalamin E defect in an adolescent patient
We report an adolescent patient with cobalamin E (CblE) defect presenting with megaloblastic anemia, mental retardation, cerebral atrophy, cortical visual impairment, white matter changes on brain magnetic resonance imaging, and hyperhomocysteinemia. Homozygous mutation at the c.245C>T in exon 3 of the MTRR gene was identified, which had been found to be related to CblE defect. He was treated with betaine, folic acid, vitamin B6, riboflavin, hydroxycobalamin (OH-B12), and carnitine. During treatment, homocysteine levels decreased over time. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - June 30, 2020 Category: Neuroscience Authors: Merve Koc Yekeduz Elif Unal Ince Talia Ileri Mehmet Ertem Fatma Tuba Eminoglu Source Type: research

Split cord malformation type 2 with double dorsal lipoma: A sequela or a chance
Mohamed A Jamaluddin, Prakash Nair, Ganesh Divakar, Jaypalsinh A Gohil, Mathew AbrahamJournal of Pediatric Neurosciences 2020 15(2):135-139An 11-month-old baby girl, with normal perinatal history, presented with a congenital lumbosacral swelling and a sacral dimple. Imaging revealed a split cord malformation (SCM) type 2 at L1–L3 with a lipomeningocoele extending intradurally and tethering both the hemicords, the conus was noted to be at L4. She underwent excision of the lipoma and detethering of the hemicords. Intraoperatively, the split cord was seen from L1 to L3 with an aberrant median vessel passing between the ...
Source: Journal of Pediatric Neurosciences - June 30, 2020 Category: Neuroscience Authors: Mohamed A Jamaluddin Prakash Nair Ganesh Divakar Jaypalsinh A Gohil Mathew Abraham Source Type: research

Primary hypokalemic periodic paralysis: Long-term management and complications in a child
Indar K Sharawat, Renu Suthar, Naveen Sankhyan, Pratibha SinghiJournal of Pediatric Neurosciences 2020 15(2):132-134Hypokalemic periodic paralysis (HPP) is a rare genetically determined neuromuscular disorder caused by mutation in skeletal muscles calcium and sodium channels. It presents with recurrent episodes of flaccid paralysis. A 9-year-old girl presented with recurrent episodic flaccid quadriparesis with complete recovery in-between the episodes. Investigations during the acute episode revealed marked hypokalemia with electrocardiogram changes. Next-generation sequencing showed pathogenic missense mutation in CACNA1S...
Source: Journal of Pediatric Neurosciences - June 30, 2020 Category: Neuroscience Authors: Indar K Sharawat Renu Suthar Naveen Sankhyan Pratibha Singhi Source Type: research

Moebius syndrome: A rare entity or a missed diagnosis ?
Sreetama Chowdhury, Shatanik Sarkar, Debasree Guha, Malay K DasguptaJournal of Pediatric Neurosciences 2020 15(2):128-131Moebius syndrome is a rare congenital neurological disease, nonprogressive in nature, characterized by weakness or palsy of multiple cranial nerves, most often the sixth and seventh cranial nerves. Third and twelfth cranial nerves are also frequently involved. Infants presenting with similar presentation are often misdiagnosed because the facial palsy is commonly attributed to other causes such as birth trauma. Here, we present a 6-week-old infant presenting with poor weight gain and feeding problem, ult...
Source: Journal of Pediatric Neurosciences - June 30, 2020 Category: Neuroscience Authors: Sreetama Chowdhury Shatanik Sarkar Debasree Guha Malay K Dasgupta Source Type: research

Intracranial rhabdomyosarcoma of the cerebellopontine angle in a 6-year-old child: A case report
Mohammad Sadegh Masoudi, Saber Zafarshamspour, Mohammad Ghasemi-Rad, Neda Soleimani, Christie LincolnJournal of Pediatric Neurosciences 2020 15(2):124-127Rhabdomyosarcoma (RMS) is the most common soft-tissue malignancy in children under 15 years of age. Approximately, 35% of RMS cases originate from the head and neck region. Among various sites in the head and neck region, intracranial extension is more likely to occur with parameningeal tumors, which is also considered an unfavorable prognostic factor in children with RMS. About 20% of RMS occurs in a parameningeal site. Intracranial RMS are rare tumors that usually arise...
Source: Journal of Pediatric Neurosciences - June 30, 2020 Category: Neuroscience Authors: Mohammad Sadegh Masoudi Saber Zafarshamspour Mohammad Ghasemi-Rad Neda Soleimani Christie Lincoln Source Type: research

A novel SCN1A mutation: A case report
Conclusion: Variant mutations of DS should be kept in mind and diagnostic genetic testing should be done in patients with neuromotor developmental retardation starting with afebrile seizures. In DS, hepatomegaly is not an expected condition. Maybe this new mutation might have caused hepatomegaly. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - June 30, 2020 Category: Neuroscience Authors: Mahmut Aslan Bilge Ozgor Serkan Kirik Serdal Gungor Source Type: research

Acute cerebral venous sinus thrombosis: A rare complication of primary varicella zoster virus infection
We report the case of a 17-years old adolescent male with left hemiparesis, cranial nerve palsies associated with primary Varicella infection. MRI revealed cerebral venous thrombosis involving right transverse sinus, sigmoid sinus, internal jugular vein and infarct involving right cerebral hemisphere, Midbrain and Pons. The patient responded well to Acyclovir, cerebral decongestants and oral anticoagulant therapy.CVT is a rare but the most life threatening complication following primary Varicella infection and early diagnosis is essential for proper management of the patient. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - June 30, 2020 Category: Neuroscience Authors: Champa Panwar Surinder Singh Neeraj Sharma Source Type: research

Infantile presentation of Lehman syndrome with multiple lateral meningoceles, dural ectasias, and herniation of conus: A rare case report
We present a case of a 5-month-old girl who presented with macrocephaly, developmental delay, and failure to thrive. A whole spine magnetic resonance imaging was carried out, which showed multiple bilateral well-defined cystic masses within the neural foramina involving the entire spine, predominantly the thoracolumbar regions, with neural foraminal widening and dural ectasia suggestive of multiple lateral meningoceles. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - June 30, 2020 Category: Neuroscience Authors: Mohan Amuthabarathi Kramadhari Harshith Krishnan Nagarajan Source Type: research

Facial dysmorphism, hirsutism, and failure to thrive as manifestation of Leigh syndrome in a child with SURF1 mutation
We report a case of 22-month-old female child presenting to us with severe failure to thrive, dysmorphic features, hirsutism, external ophthalmoplegia epilepsy, and neuroregression with characteristic findings of Leigh’s syndrome on neuroimaging and her muscle biopsy revealed evidence of mitochondrial respiratory chain defect involving complex IV and SURF1 mutation. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - June 30, 2020 Category: Neuroscience Authors: Dhinesh Baskaran Nahin Hussain Source Type: research

Multiple cerebral hemorrhages during the course of Guillain & #8211;Barre syndrome: A case report
In this report, we present a 3-year-old girl diagnosed with cortical and subcortical hemorrhage during the course of GBS who was treated with intravenous immunoglobulin. To the best of our knowledge, central nervous system hemorrhage during the course of GBS is an extremely rare condition. We believe that all clinicians following patients with GBS or using intravenous immunoglobulin for any indications should be aware of this rare but potentially life-threatening condition. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - June 30, 2020 Category: Neuroscience Authors: Sedat ISIKAY Akif SIRIKCI Source Type: research

Increased hemoglobin and plateletcrit levels indicating hemoconcentration in pediatric patients with migraine
Conclusion: This study suggests that migraine may be accompanied with hemoconcentration in children. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - June 30, 2020 Category: Neuroscience Authors: Sevim Sahin Betul Diler Durgut Beril Dilber Elif Acar Arslan Tulay Kamasak Ali Cansu Source Type: research

Clinico-radiological profile of children with pontocerebellar hypoplasia
Conclusion: A heightened index of suspicion for PCH is merited in infants with progressive psychomotor retardation and severe microcephaly. Cerebellar hypoplasia with pontine attenuation forms the mainstay of diagnosis of PCH (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - June 30, 2020 Category: Neuroscience Authors: Ananthanarayanan Kasinathan Naveen Sankhyan Tessa Van Dijk Paramjeet Singh Pratibha Singhi Source Type: research

Facebook and WhatsApp in identifying current practices of neurological physiotherapy intervention in neonatal intensive care units: In Indian scenario
Conclusion: Less than 50% physiotherapy students performed neurological physiotherapy intervention in NICU. Therefore, more awareness needs to be created regarding neurological physiotherapy intervention performed in NICU. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - June 30, 2020 Category: Neuroscience Authors: Neha Sharma Krati Omar Navjyoti Gupta Asir John Samuel Source Type: research

Clinical features and molecular genetics of autosomal recessive ataxia in the Turkish population
Conclusion: The prevalence of hereditary ataxia can vary among countries. The consanguineous marriage is an important finding in these diseases. These genetic tests will increase the number of ARCA patients diagnosed. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - June 30, 2020 Category: Neuroscience Authors: Faruk Incecik Ozlem M Herguner Neslihan O Mungan Source Type: research

Effect of levetiracetam usage on serum creatine phosphokinase concentration in patients with epilepsy
Conclusion: We detected that LEV may cause increased CPK concentration or rhabdomyolysis. When treating patients with LEV, clinicians should closely monitor serum CPK level. To the best of our knowledge, this is the first study of elevated CPK concentration or rhabdomyolysis associated with LEV therapy in children. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - June 30, 2020 Category: Neuroscience Authors: Faruk Incecik Ozlem M Herguner Seyda Besen Source Type: research

Craniosynostosis: To study the spectrum and outcome of surgical intervention at a tertiary referral institute in India
Conclusion: The study highlights the importance of educating the masses so that cases of craniosynostosis present early. The incidence of Chiari malformation, intracranial hypertension, and perioperative complications was significantly higher in the syndromic craniosynostosis and oxycephaly groups than in single-suture craniosynostosis. The best surgical outcome and the least perioperative complications were seen in the trigonocephaly group. Compromised overall correction and reoperations were more common in the syndromic and complex craniosynostosis groups than in single-suture craniosynostosis. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - June 30, 2020 Category: Neuroscience Authors: Charandeep S Gandhoke Simran K Syal Ajay Sharma Arvind K Srivastava Daljit Singh Source Type: research

COVID-19. The missing link
Dattatraya MuzumdarJournal of Pediatric Neurosciences 2020 15(2):69-71 (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - June 30, 2020 Category: Neuroscience Authors: Dattatraya Muzumdar Source Type: research

Coexistence of type 1 diabetes mellitus and periventricular heterotopia in a child: A case report
Faruk Incecik, Fatih GürbüzJournal of Pediatric Neurosciences 2020 15(1):67-68 (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - March 19, 2020 Category: Neuroscience Authors: Faruk Incecik Fatih G & #252;rb & #252;z Source Type: research

Hereditary chin trembling
Sedat IsikayJournal of Pediatric Neurosciences 2020 15(1):66-66 (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - March 19, 2020 Category: Neuroscience Authors: Sedat Isikay Source Type: research

Prevalence of unrecognized autism spectrum disorders in epilepsy: A clinic-based study
Mahmood D Al-MendalawiJournal of Pediatric Neurosciences 2020 15(1):65-65 (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - March 19, 2020 Category: Neuroscience Authors: Mahmood D Al-Mendalawi Source Type: research

Black holes in the brain and spine: A dark disease
This article emphasizes the importance of recognizing its classical neuroimaging findings distinct from other disorders. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - March 19, 2020 Category: Neuroscience Authors: Bhanudeep Singanamalla Sumeet Dhawan Arushi Gahlot Saini Paramjeet Singh Naveen Sankhyan Source Type: research

Miller Fisher variant of Guillain & #8211;Barr & #233; syndrome in a child
We describe the case of a 7-year-old boy who presented with diplopia, speech difficulty, dysphagia, gait disturbance, and difficulty in eyeball movements since 5 days. On examination, the child was having ataxia, areflexia, ophthalmoplegia, drooling of saliva, dysphonia, and absent gag reflex. MFS and brain stem encephalitis were kept as the differential diagnoses. The patient improved gradually over 3 weeks, following a treatment with intravenous immunoglobulin. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - March 19, 2020 Category: Neuroscience Authors: Sushant S Mane Umesh Nagesh Vaijinath T Sathe Jyothi Janadhanan Source Type: research

An unusual presentation of Menkes disease masquerading as a leukodystrophy with macrocephaly
Conclusion: This case exemplifies a rare presentation of Menkes disease, simulating a leukodystrophy with macrocephaly. Tortuosity of cerebral blood vessels is an important finding, which can help in differentiating Menkes disease from white matter disorders. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - March 19, 2020 Category: Neuroscience Authors: Anshula Tayal Aman Elwadhi Suvasini Sharma Bijoy Patra Source Type: research

A case of deep cerebral venous thrombosis presenting like acute necrotizing encephalopathy
We report a case of 2½-year-old child who presented like acute necrotizing encephalopathy but on further investigations was found to be having deep cerebral vein thrombosis. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - March 19, 2020 Category: Neuroscience Authors: Sachin Dangi Namita Gwasikoti Source Type: research

Reports of a conus cauda tumor with holocord syrinx in an adolescent girl
We report a case highlighting these findings. Case Report: A 16-year-old adolescent presented critically ill with respiratory failure due to severe pneumonia. Evaluation showed fungal pneumonia with secondary bacterial infection. On recovery, she had nasal regurgitation and required nasogastric tube feeding. Examination showed palatal and left vocal cord palsy. Neuroimaging of brain showed conus cauda tumor with syringobulbia and holocord multiseptate syrinx extending from medulla to filum terminale with lipoma. Histopathology examination showed myxopapillary ependymoma. She improved with excision and postoperative radioth...
Source: Journal of Pediatric Neurosciences - March 19, 2020 Category: Neuroscience Authors: Smriti Sinha Prathibha Shankar Ashwini Pelala Nayan Baba Rathika Damodar Shenoy Source Type: research

Myelopathy in two brothers with respiratory chain disorder & #8211;severe complex 1 deficiency with atlantoaxial dislocation and long spinal arachnoid cyst: A new unreported association
Sadanandavalli Retnaswami Chandra, Hansashree Padmanabha, Manisha Gupta, Nupur Pruthi, Gayathri Narayanappa, Rita ChristopherJournal of Pediatric Neurosciences 2020 15(1):45-50Billion of years ago bacteria is believed to have entered a eukaryotic cell and converted to mitochondria. The respiratory chain present in it supplies ATP to all cells and therefore the diseases can have any phenotype. Diagnosis may be difficult to confirm by the conventional methods including genetics. Two brothers born to consanguineous parents had global delay, mild visual impairment and drooping of eyelids since birth in the elder child and dysm...
Source: Journal of Pediatric Neurosciences - March 19, 2020 Category: Neuroscience Authors: Sadanandavalli Retnaswami Chandra Hansashree Padmanabha Manisha Gupta Nupur Pruthi Gayathri Narayanappa Rita Christopher Source Type: research

A case of split notochord syndrome with left congenital diaphragmatic hernia: A rare association
Pradyumna PanJournal of Pediatric Neurosciences 2020 15(1):42-44Split notochord syndrome is a rare neural tube malformation involving the brain, spinal cord, and vertebral column. In nearly half of the cases, the malformation also involves the gastrointestinal tract in the form of a dorsal neurenteric fistula and imperforate anus. In the literature, less than 50 cases have been reported. To the best of my knowledge, this is the first reported case associated with a left congenital diaphragmatic hernia. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - March 19, 2020 Category: Neuroscience Authors: Pradyumna Pan Source Type: research

Multiple tubercular brain abscesses with obstructive hydrocephalus in an immunocompetent child: A case report
Ipsita K Sahoo, Amit K Satapathy, Joseph JohnJournal of Pediatric Neurosciences 2020 15(1):38-41Tubercular brain abscesses are rare manifestations in children, and very few cases have been reported till date. It is characterized by an encapsulated collection of pus, containing viable tubercular bacilli. Antitubercular treatment (ATT) is the mainstay of treatment along with surgical drainage or aspiration or excision of the abscess. We hereby report a case of a 15-month-old child with multiple tubercular brain abscesses with obstructive hydrocephalus, managed with ATT and ventriculoperitoneal shunt. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - March 19, 2020 Category: Neuroscience Authors: Ipsita K Sahoo Amit K Satapathy Joseph John Source Type: research

Acute hydrocephalus in a case of mumps meningoencephalitis: A rare occurrence
Anish Mehta, Rohan Mahale, Kiran Khanapure, Anirudh T Jagannatha, Purushottam Acharya, Rangasetty SrinivasaJournal of Pediatric Neurosciences 2020 15(1):34-37Mumps is an acute viral illness, which presents with glandular and/or nervous system involvement. The most common central nervous system manifestations of mumps include aseptic meningitis and meningoencephalitis. Mumps meningoencephalitis, which is characterized by fever, vomiting, nuchal rigidity, and altered sensorium, usually develops at least 3–10 days after mumps parotitis. Acute hydrocephalus secondary to mumps meningoencephalitis is rare. Here we report a...
Source: Journal of Pediatric Neurosciences - March 19, 2020 Category: Neuroscience Authors: Anish Mehta Rohan Mahale Kiran Khanapure Anirudh T Jagannatha Purushottam Acharya Rangasetty Srinivasa Source Type: research

Electroclinical findings of SYNJ1 epileptic encephalopathy
Conclusion: This is a newly described early-onset epileptic encephalopathy secondary to a critical reduction of the dual phosphatase activity of SYNJ. Clinical features include early-onset intractable focal, myoclonic seizures, infantile spasms, and hypotonia progressing to spastic quadriparesis, opisthotonus, dystonia, profound developmental delay, and a progressive neurodegenerative course. Brain magnetic resonance imaging is usually normal. Electroencephalography shows diffuse slowing with multifocal epileptiform discharges or modified hypsarrhythmia. These findings further expand the clinical spectrum of synaptic dysre...
Source: Journal of Pediatric Neurosciences - March 19, 2020 Category: Neuroscience Authors: Debopam Samanta Kapil Arya Source Type: research

A rare case of sphenoid encephalocoele presenting with fifth cranial nerve involvement
Rohit Wadikhaye, Vamsi Krishna Yerramneni, Thirumal Yerragunta, Neeraj SharmaJournal of Pediatric Neurosciences 2020 15(1):25-28A 14-year-old girl presented with chronic headache, recurrent episodes of vomiting, fever, and two episodes of generalized tonic clonic seizure in the past 2 months. Neuroimaging revealed herniation of the brain along with the dura through a defect in the left greater wing of the sphenoid. Left pterional craniotomy was carried out. Herniation of the dural sac along with its contents through the bony defect in the greater sphenoid wing was identified lateral to the V2 nerve passing through the fora...
Source: Journal of Pediatric Neurosciences - March 19, 2020 Category: Neuroscience Authors: Rohit Wadikhaye Vamsi Krishna Yerramneni Thirumal Yerragunta Neeraj Sharma Source Type: research

Prevalence of vitamin B12 deficiency in West syndrome: A retrospective chart review
Conclusion: In this limited cross-sectional study, vitamin B12 was deficient in 7.7% of children with West syndrome with lack of reduction in frequency of spasm on B12 supplementation. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - March 19, 2020 Category: Neuroscience Authors: Manjeet Singh Mohit Bansal Jaya S Kaushik Source Type: research

Intravenous levetiracetam for treatment of seizures in term and preterm neonates
Conclusion: Our data suggest that levetiracetam may be a safe and effective treatment for neonatal seizures, which are unresponsive to phenobarbital. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - March 19, 2020 Category: Neuroscience Authors: Pakize Karaoglu Semra H & #305;z Bur & #231;in & #304; & #351;can Ay & #351;e & #304; Polat M & #252;ge Ayano & #287;lu Nuray Duman Ulu & #231; Yis & #807; & #8217; Source Type: research

Auditory and visual P300 responses in early cognitive assessment of children and adolescents with epilepsy
Conclusion: Visual and auditory P300 latencies have an important role in the evaluation of early cognitive dysfunctions in children with epilepsy. P300 potentials are not influenced by antiepileptic treatment, whereas the type of epilepsy alters them (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - March 19, 2020 Category: Neuroscience Authors: Sangeeta Gupta Arun Prasad Ramji Singh Gaurav Gupta Source Type: research

Relation between febrile seizure recurrence and hyponatremia in children: A single-center trial
Conclusion: Although the results did not show that the lower level of serum sodium increased the risk of seizure recurrence during the next 24h in febrile illness, lower serum sodium concentration was more common in FS groups. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - March 19, 2020 Category: Neuroscience Authors: Mohammad Reza Navaeifar Ali Abbaskhanian Akram Farmanbarborji Source Type: research

Postoperative pneumoventricle following posterior fossa tumor surgery in sitting position: Plugging the aqueduct
Dattatraya MuzumdarJournal of Pediatric Neurosciences 2020 15(1):1-4 (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - March 19, 2020 Category: Neuroscience Authors: Dattatraya Muzumdar Source Type: research

Pressure inside endoscope: An important intraoperative surrogate!
Indu Kapoor, Hemanshu Prabhakar, Charu MahajanJournal of Pediatric Neurosciences 2019 14(4):238-238 (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - December 5, 2019 Category: Neuroscience Authors: Indu Kapoor Hemanshu Prabhakar Charu Mahajan Source Type: research

Unilateral cerebellar hypoplasia: A rare cause of childhood seizures
We describe a case of 14 years old boy with unilateral cerebellar hypoplasia and recurrent seizures with emphasis on the MRI features of this rare entity. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - December 5, 2019 Category: Neuroscience Authors: Minhaj Shaikh Pushpinder Khera Samhita Panda Source Type: research

Hypocalcemic recurrent generalized seizures with bilateral basal ganglia and frontal calcification as the initial manifestation of Albright & #8217;s hereditary osteodystrophy in a child: A pictorial and video-graphic representations
In this study, we report a 14-year-old boy with distinctive phenotype of AHO, oral manifestations, and signs of tetany with PHP presenting as recurrent generalized seizure. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - December 5, 2019 Category: Neuroscience Authors: Akhilesh Kumar Nunavath Sandhya Manorenj Srikant Jawalker Bushra Naaz Source Type: research

Do Glioblastomas with Syndromic Association Have Better Prognosis ? A Case of Supratentorial Glioblastoma with Embryonal Tumor Differentiation in a Child with Multiple Enchondromatosis
We report a case of a 10-year-old boy presenting with a supratentorial GBM, isocitrate dehydrogenase wild type with ET differentiation, and multiple benign bony lesions of both extremities. He underwent surgical excision for the brain neoplasm followed by radiotherapy and has shown prolonged survival with no recurrence. In this article, we discuss prognostic factors associated with long-term survival of these tumors. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - December 5, 2019 Category: Neuroscience Authors: Siddharth Vankipuram Sushant Sahoo Shalini Bhalla Chittij Srivastava Source Type: research

Unilateral open-lip schizencephaly with tonsillar herniation in a preterm infant
We report a rare case of prenatally diagnosed unilateral schizencephaly in a late preterm infant who manifested with rapidly progressive hydrocephalus with massive enlargement of posterior cerebrospinal fluid spaces with tonsillar herniation that was successfully treated with placement of a ventriculoperitoneal shunt. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - December 5, 2019 Category: Neuroscience Authors: Juan Carlos Gonzalez Kanya Singhapakdi Anthony M Martino Bassam H Rimawi Ramachandra Bhat Source Type: research

KLHL40 mutation associated with severe nemaline myopathy, fetal akinesia, and cleft palate
Kapil K Avasthi, Sarita Agarwal, Inusha PanigrahiJournal of Pediatric Neurosciences 2019 14(4):222-224The congenital myopathies are a heterogeneous group of inherited neuromuscular disorders characterized by early-onset muscular weakness, hypotonia, and developmental delay. The congenital myopathies are further classified into centranuclear myopathies, nemaline myopathies, core myopathies, and congenital fiber-type disproportion based on major pathological features found in muscle biopsies. There is no evidence at present to show that cleft palate is associated with severe nemaline myopathies and fetal akinesia. The result...
Source: Journal of Pediatric Neurosciences - December 5, 2019 Category: Neuroscience Authors: Kapil K Avasthi Sarita Agarwal Inusha Panigrahi Source Type: research