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Clinical characteristics, outcomes and risk factors for mortality in hospitalized diabetes and chronic kidney disease patients after COVID-19 infection following widespread vaccination
ConclusionsThese findings highlight the critical importance of identifying and managing comorbid risk factors for COVID-19, especially among the elderly, in order to optimize clinical outcomes, even after COVID-19 vaccination.
Source: Journal of Endocrinological Investigation - September 19, 2023 Category: Endocrinology Source Type: research

Association Between Cervical Fracture Patterns and Blunt Cerebrovascular Injury When Screened with Computed Tomographic Angiography
Vertebral artery injury (VAI) is estimated to be present in upwards of 0.7% of all patients who sustain blunt trauma [1 –7], and in 19-39% of all cervical spine fractures. This is likely due to the close anatomic relationship between the cervical spine and the vertebral arteries. There has been significant interest in determining the risk factors for development of VAI and carotid artery injuries (CAI) because of t he potentially catastrophic outcomes in a missed posterior circulation stroke. If undetected blunt cerebrovascular injuries (BCVI), which include both VAI and CAIs, have significant morbidity and mortality wit...
Source: The Spine Journal - September 19, 2023 Category: Orthopaedics Authors: Peter Z Du, Nicholas D Christopher, Venkat Ganapathy Tags: Clinical Study Source Type: research

Adult mortality trends in Matlab, Bangladesh: an analysis of cause-specific risks
Conclusion Deaths from stroke, heart disease and cancers were either on the rise or remained unchanged, but other causes declined continuously from 2003 to 2017. Immediate strengthening of the preventive and curative healthcare systems for NCDs management is a burning need.
Source: BMJ Open - September 19, 2023 Category: General Medicine Authors: Ahmed, A., Nahian, M. A., Rahman, M. M., Alam, N., Nahar, Q., Streatfield, P. K., Haider, M. M., Rahman, M. Tags: Open access, Public health Source Type: research

Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Behavioral Phenotyping
ConclusionsThe proposed behavioral phenotyping CDEs will assist with international harmonization of DoC studies and allow for more precise characterization of study cohorts, favorably impacting observational studies and clinical trials aimed at improving outcome in this population.
Source: Neurocritical Care - September 19, 2023 Category: Neurology Source Type: research

Multi-Channel FES Gait Rehabilitation Assistance System Based on Adaptive sEMG Modulation
This study proposes a multi-channel FES gait rehabilitation assistance system based on adaptive myoelectric modulation. The proposed system collects sEMG of the vastus lateralis muscle on the non-affected side to predict the sEMG values of four targeted lower-limb muscles on the affected side using a bidirectional long short-term memory (BILSTM) model. Next, the proposed system modulates the real-time FES output frequency for four targeted muscles based on the predicted sEMG values to provide muscle force compensation. Fifteen healthy subjects were recruited to participate in an offline model-building experiment conducted ...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - September 18, 2023 Category: Neuroscience Source Type: research

Blood biomarker changes following therapeutic hypothermia in ischemic stroke
ConclusionAlthough the exact roles of MMP3, FABP, and IL-8 in hypothermia-treated stroke patients are not known, further exploration is needed to confirm their roles in brain ischemia.
Source: Brain and Behavior - September 18, 2023 Category: Neurology Authors: Elena Pal à, Anna Penalba, Alejandro Bustamante, Teresa García‐Berrocoso, Marcel Lamana‐Vallverdú, Christian Meisel, Andreas Meisel, H. Bart van der Worp, Malcolm R Macleod, Bernd Kallmünzer, Stefan Schwab, Joan Montaner Tags: BRIEF REPORT Source Type: research

Cerebral embolic protection during transcatheter heart interventions
EuroIntervention. 2023 Sep 18;19(7):549-570. doi: 10.4244/EIJ-D-23-00166.ABSTRACTStroke remains a devastating complication of transcatheter aortic valve replacement (TAVR), with the incidence of clinically apparent stroke seemingly fixed at around 3% despite TAVR's significant evolution during the past decade. Embolic showers of debris (calcium, atheroma, valve material, foreign material) are captured in the majority of patients who have TAVR using a filter-based cerebral embolic protection device (CEPD). Additionally, in systematic brain imaging studies, the majority of patients receiving TAVR exhibit new cerebral lesions...
Source: EuroIntervention - September 18, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Victor Alfonso Jimenez Diaz Samir R Kapadia Axel Linke Darren Mylotte Alexandra J Lansky Eberhard Grube Magnus Settergren Rishi Puri Source Type: research

Perceived Level of Life Enjoyment and Risk of Developing Disabling Dementia: The Japan Public Health Center-Based Study
DISCUSSION: A higher level of life enjoyment was associated with a lower risk of disabling dementia, particularly in the low-medium mental stress group. This finding suggests the importance of having life enjoyment by managing mental stress for reducing risk of disabling dementia.PMID:37718836 | DOI:10.1093/geronb/gbad129
Source: Cancer Control - September 18, 2023 Category: Cancer & Oncology Authors: Tomokazu Tajima Ai Ikeda Takeshi Tanigawa Hiroyasu Iso Kazumasa Yamagishi Takumi Matsumura Nobufumi Yasuda Manami Inoue Shoichiro Tsugane Norie Sawada Japan Public Health Center –Based Study Group Source Type: research

Single-center experience of endovascular treatment for patients with progressive posterior circulation cerebral infarction exceeding 24 h
CONCLUSION: In patients with progressive posterior circulation cerebral infarction caused by vertebral basilar artery occlusion, ET is effective and safe even if the time from onset to puncture exceeds 24 h.PMID:37719319 | PMC:PMC10505061 | DOI:10.2478/abm-2023-0046
Source: Biomed Res - September 18, 2023 Category: Research Authors: Guangfeng Zhao Xiongjun He Yajie Liu Liang Zhang Kaifeng Li Source Type: research

Atherosclerosis as a Risk Factor for IBD: A Population-Based Case-Control Study
CONCLUSIONS: A history of an atherosclerotic-related condition is associated with increased odds of developing IBD, particularly among older adults. Future studies should investigate whether drugs targeting atherosclerotic-related inflammation may prevent IBD in higher-risk individuals.PMID:37721310 | DOI:10.14309/ajg.0000000000002502
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Adam S Faye Jordan Axelrad Jiangwei Sun Jonas Halfvarson Jonas S öderling Ola Ol én Jonas F Ludvigsson Source Type: research

Understanding the Link Between Adult Asthma and Coronary Artery Disease: A Narrative Review
Cureus. 2023 Aug 17;15(8):e43621. doi: 10.7759/cureus.43621. eCollection 2023 Aug.ABSTRACTAsthma is a common pathology worldwide that occurs due to chronic inflammation of the respiratory airways. Persistent pulmonary inflammation leads to low-grade systemic inflammation, influencing blood vessels and triggering coronary artery disease (CAD) events. This review's objectives include discussing the susceptible population for CAD, the mechanism underlying CAD creation in asthma patients, the characteristics of asthma, and the influence of anti-asthmatic medications on CAD development. Adult-onset asthma is strongly linked to ...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Vasudha S Garg Mihir H Sojitra Tyagi J Ubhadiya Nidhi Dubey Karan Shah Siddharth Kamal Gandhi Priyansh Patel Source Type: research

Role of TRPV1 in electroacupuncture-mediated signal to the primary sensory cortex during regulation of the swallowing function
CONCLUSION: The TRPV1 at CV23 after EA treatment might play a key role in mediating local blood perfusion but was not involved in transferring EA signals to the central nervous system (CNS). These findings collectively suggested that TRPV1 may be one of the important regulators involved in the mechanism of EA treatment for improving swallowing function in PSD.PMID:37718934 | DOI:10.1111/cns.14457
Source: CNS Neuroscience and Therapeutics - September 18, 2023 Category: Neuroscience Authors: Si Yuan Bo Qiu Ying Liang Bing Deng Jing Xu Xiaorong Tang Junshang Wu Sheng Zhou Zeli Li Hongzhu Li Qiuping Ye Lin Wang Shuai Cui Chunzhi Tang Wei Yi Lulu Yao Nenggui Xu Source Type: research

Neurophysiological characterization of stroke recovery: A  longitudinal TMS and EEG study
CONCLUSION: Our results demonstrate prominent clinical implications for individualized stroke rehabilitation based on both functional integrity of the ipsilesional corticomotor pathway and motor function.PMID:37718708 | DOI:10.1111/cns.14471
Source: CNS Neuroscience and Therapeutics - September 18, 2023 Category: Neuroscience Authors: Qian Ding Jixiang Chen Shunxi Zhang Songbin Chen Xiaotong Li Yuan Peng Yujie Chen Junhui Chen Kang Chen Guiyuan Cai Guangqing Xu Yue Lan Source Type: research

Effectiveness of mid thoracic spine mobilization on postural balance and gait ability in subacute stroke patients: A randomized clinical trial
CONCLUSIONS: Mid-thoracic spine mobilization allows significant improvements in postural balance and gait ability in subacute stroke patients, with no differences between the SNAG and MM techniques.PMID:37718778 | DOI:10.3233/BMR-230144
Source: Journal of Back and Musculoskeletal Rehabilitation - September 18, 2023 Category: Orthopaedics Authors: Jinhong Kim Juchul Cho Source Type: research