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After 6 Brain Surgeries and a Stroke, Resident Aims to Inspire Others
(MedPage Today) -- Claudia Martinez, MD, a third-year resident at TIRR Memorial Hermann in Houston, always knew she wanted to become a physician. Growing up, she envisioned being able to give back to small towns like the ones her parents were...
Source: MedPage Today Neurology - August 12, 2022 Category: Neurology Source Type: news

How to Exercise When It ’ s Really Hot Outside
For people in many parts of the U.S.—as well as large portions of the world—the phrase “record heat” has been a regular part of the recent forecast. While that doesn’t mean you have to move your favorite outdoor workout into the gym, you may need to do it a little differently. Here’s what experts recommend for staying safe and active outdoors. How hot is too hot to exercise outside? There’s no precise temperature at which it becomes unsafe to exercise. It comes down to individual factors, according to Melissa Kendter, a personal trainer, running coach, and functional training speci...
Source: TIME: Health - August 11, 2022 Category: Consumer Health News Authors: Elizabeth Millard Tags: Uncategorized climate change Exercise & Fitness freelance healthscienceclimate Source Type: news

How to live longer: The red snack that can reduce your risk of stroke by 59%
ONE of the ways to a longer life is staving off life-threatening conditions like strokes. Fortunately, research suggests that a certain snack can lower your risk of this medical emergency by a whopping 59 percent. What's more, enjoying the little food could also see your blood pressure fall.
Source: Daily Express - Health - August 11, 2022 Category: Consumer Health News Source Type: news

Outcomes of endovascular treatment of thoracic aorta pathologies: 10-year single-center results
CONCLUSION This study reported the outcomes of TEVAR treatment from a tertiary medical center in Turkey over a decade. Patients presenting with acute symptoms and who developed stroke and acute renal failure after the procedure should be carefully followed up as these factors were found to be associated with mortality.PMID:35950282 | DOI:10.5152/dir.2022.211293
Source: Diagnostic and Interventional Radiology - August 11, 2022 Category: Radiology Authors: Mustafa Emre Ak ın Koray Akkan Abdullah Özer Erhan Turgut Ilg ıt Baran Önal G ürsel Levent Oktar Source Type: research

Spontaneous cervical epidural haematoma mimicking stroke: a  case report and literature review
Folia Neuropathol. 2022;60(2):261-265. doi: 10.5114/fn.2022.116940.ABSTRACTSpontaneous spinal epidural haematoma (SSEH) is a rare disease that requires emergency decompression or haematoma evacuation to prevent permanent neurological deficits. Hemiparesis is an extremely rare presentation of SSEH, commonly misdiagnosed as stroke. With the help of case studies and references, this paper comprehensively discusses the effective methods to distinguish SSEH from stroke and provides theoretical support and ideas for rapid and accurate identification of SSEH. Herein, we report on the case of a 51-year-old man with SSEH who presen...
Source: Folia Neuropathologica - August 11, 2022 Category: Pathology Authors: Tian Lv Yaya Bao Jingjing Lou Dadong Gu Source Type: research

Low-frequency repetitive transcranial magnetic stimulation to the right Broca mirror area for improving auditory comprehension in a  sensory aphasia after stroke: a case report
This study reported one stroke patient with sensory aphasia who received 6 treatment sessions of low-frequency rTMS before speech and language therapy. The target area was the Broca mirror area in the right hemisphere. After treatment, the auditory comprehension of the patient improved from 46 to 112, the naming improved from 18 to 32, and the AQ improved from 34.2 to 42.6. However, the level of functional language, spontaneous speech and repetition did not show obvious improvement.PMID:35950478 | DOI:10.5114/fn.2022.118188
Source: Folia Neuropathologica - August 11, 2022 Category: Pathology Authors: Qing-Qing Liu Wei-Bo Li Zhen-Biao Zhao Wei-Guo Zhang Pei-Yuan Lv Yu-Hui Yang Yu Yin Source Type: research

Diagnostic performance of miR-21, miR-124, miR-132, and miR-200b serums in post-stroke cognitive impairment patients
CONCLUSIONS: The miR-21 alone or combination of miR-21 and FA values are valuable diagnostic biomarkers in discriminating PSCI from PSCN.PMID:35950475 | DOI:10.5114/fn.2022.118187
Source: Folia Neuropathologica - August 11, 2022 Category: Pathology Authors: Mei Yuan Yi-Sha Guo Xin-Xin Zhang Zhen-Kun Gao Xin-Ya Shen Yu Han Xia Bi Source Type: research

Relation of post-stroke headachto cerebrovascular pathology and hemodynamics
In conclusion, post-stroke headache is a common phenomenon, especially in patients with pre-stroke headache, history of old stroke, posterior circulation infarction, and large artery disease. This headache was of moderate-intensity with clinical characteristics of tension-type. Intra-cranial cerebrovascular pathological changes including opening of collateral channels and variable degrees of stenosis of cerebrovascular systems were implicated in the production of that headache.PMID:35950474 | DOI:10.5114/fn.2022.116962
Source: Folia Neuropathologica - August 11, 2022 Category: Pathology Authors: Elsayed Abed Nabil Hussein Mohammed Ahmed Hassan Elsheshiny Sandra Ahmed Mohamed Hamed Rashad Source Type: research

Identification of a  miRNA biomarker for the large artery atherosclerosis subtype of acute ischemic stroke
CONCLUSIONS: miR-129-1-3p may be a relevant biomarker for the diagnosis of stroke caused by large artery atherosclerosis and could represent a novel therapeutic target for stroke treatment.PMID:35950473 | DOI:10.5114/fn.2022.117248
Source: Folia Neuropathologica - August 11, 2022 Category: Pathology Authors: Bo Zhou Bo Li Pin Feng Xin Wang He Gao Lifang Xu Tianyi Wang Xiaoling Guo Source Type: research

Effect of transcranial direct current stimulation combined with a  smart hand joint training device on hand dysfunction in patients with early stroke
CONCLUSIONS: Both the smart hand joint training device alone and tDCS combined with the smart hand joint training device can improve hand function of patients with early stroke to varying degrees, but the treatment effect of tDCS combined with the smart hand joint training device is more significant.PMID:35950470 | DOI:10.5114/fn.2022.117534
Source: Folia Neuropathologica - August 11, 2022 Category: Pathology Authors: Long Zhao Zibo Liu Qingfeng Sun Hongling Li Source Type: research

Outcomes of endovascular treatment of thoracic aorta pathologies: 10-year single-center results
CONCLUSION This study reported the outcomes of TEVAR treatment from a tertiary medical center in Turkey over a decade. Patients presenting with acute symptoms and who developed stroke and acute renal failure after the procedure should be carefully followed up as these factors were found to be associated with mortality.PMID:35950282 | DOI:10.5152/dir.2022.211293
Source: Diagnostic and Interventional Radiology : The Turkish Society of Radiology - August 11, 2022 Category: Radiology Authors: Mustafa Emre Ak ın Koray Akkan Abdullah Özer Erhan Turgut Ilg ıt Baran Önal G ürsel Levent Oktar Source Type: research

NO/cGMP/PKG pathway in platelets:the therapeutic potential of PDE5 inhibitors in platelet disorders
J Thromb Haemost. 2022 Aug 11. doi: 10.1111/jth.15844. Online ahead of print.ABSTRACTPlatelets are the "guardians" of the blood circulatory system. At sites of vessel injury, they ensure hemostasis and promote immunity and vessel repair. However, their uncontrolled activation is one of the main drivers of thrombosis. To keep circulating platelets in a quiescent state, the endothelium releases platelet antagonists including nitric oxide (NO) that acts by stimulating the intracellular receptor guanylyl cyclase (GC). The latter produces the second messenger cyclic guanosine-3',5'-monophosphate (cGMP) that inhibits platelet ac...
Source: Thrombosis and Haemostasis - August 11, 2022 Category: Hematology Authors: Anisa Degjoni Federica Campolo Lucia Stefanini Mary Anna Venneri Source Type: research

Clot-targeted magnetic hyperthermia permeabilizes blood clots to make them more susceptible to thrombolysis
CONCLUSIONS: This study demonstrates that clot-targeted MH can enhance the thrombolysis of contracted human blood clots and can be safely applied to enhance the timeframe in which thrombolysis is effective.PMID:35950914 | DOI:10.1111/jth.15846
Source: Thrombosis and Haemostasis - August 11, 2022 Category: Hematology Authors: David Cabrera Maneea Eizadi Sharifabad Jacob A Ranjbar Neil D Telling Alan G S Harper Source Type: research

ASAP Effect of Tetrahedral Framework Nucleic Acids on Neurological Recovery via Ameliorating Apoptosis and Regulating the Activation and Polarization of Astrocytes in Ischemic Stroke
ACS Applied Materials& InterfacesDOI: 10.1021/acsami.2c10364
Source: ACS Applied Materials and Interfaces - August 11, 2022 Category: Materials Science Authors: Mi Zhou, Tianxu Zhang, Xiaolin Zhang, Mei Zhang, Shaojingya Gao, Tao Zhang, Songhang Li, Xiaoxiao Cai, Jun Li, and Yunfeng Lin Source Type: research

The effect of a home-based coaching program on heart rate variability in subacute stroke patients: a randomized controlled trial
Autonomic imbalance in stroke is characterized by increased sympathetic activity and reduced vagal nerve activity. Physical activity could be a strategy to counteract autonomic control impairments after a stroke. The aim of the study was to evaluate the effect on heart rate variability of a 6-month coaching program in a home setting in subacute stroke patients. Eighty-four stroke patients participated in the study. They were randomly assigned to the experimental group or the control group. The intervention was a coaching program, consisting of physical activity, home visits and a weekly phone call. Patients were evaluated ...
Source: International Journal of Rehabilitation Research - August 11, 2022 Category: Rehabilitation Tags: Original articles Source Type: research