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Mediterranean-style diet and intracranial large artery stenosis in the Northern Manhattan Study
Intracranial large artery stenosis (ICAS) is one of the most common causes of stroke worldwide.1 Among stroke-free community-dwelling adults, ICAS is prevalent, associated with modifiable vascular risk factors, and confers risk of incident vascular events.2 Given prior work linking a Mediterranean-style diet (MeDi), which is rich in fruits, vegetables, fish, whole grains, legumes, and nuts, to reduced risk of vascular conditions and cardiovascular events,3,4 we hypothesized MeDi may also be protective against ICAS.
Source: Journal of Stroke and Cerebrovascular Diseases - September 20, 2023 Category: Neurology Authors: Dixon Yang, Hannah Gardener, Farid Khasiyev, Tatjana Rundek, Clinton B Wright, Mitchell SV Elkind, Jose Gutierrez Source Type: research

Outcomes of hemorrhagic stroke in patients with autoimmune rheumatic diseases: An analysis of the US Nationwide Inpatient Sample
ConclusionsAmong patients admitted to US hospitals for hemorrhagic stroke, patients with RA had decreased risk for in-hospital mortality and prolonged LOS.
Source: International Journal of Rheumatic Diseases - September 20, 2023 Category: Rheumatology Authors: Mao ‐Yu Chen, Pin‐Yuan Chen, Chen‐Nen Chang, Bo‐An Chen, Wen‐Chun Deng, Jiun‐Lin Yan Tags: ORIGINAL ARTICLE Source Type: research

Gait analysis patterns and rehabilitative interventions to improve gait in persons with hereditary spastic paraplegia: a systematic review and meta-analysis
ConclusionKnee hyperextension, non-sagittal pelvic movements, and reduced ROM at the knee, ankle, and hip represent the most peculiar patterns in HSP, compared to diplegic cerebral palsy and stroke. Botulinum improved comfortable gait velocity after 2 months. Nonetheless, interventions reducing spasticity might result in ineffective functional outcomes unveiling weakness. Intensive active physical therapy and FES might improve gait velocity in the very short term.
Source: Frontiers in Neurology - September 20, 2023 Category: Neurology Source Type: research

Cerebral artery signal intensity gradient from Time-of-Flight Magnetic Resonance Angiography and clinical outcome in lenticulostriate infarction: a retrospective cohort study
ConclusionCerebral artery SIG from TOF-MRA was significantly associated with short-term functional outcomes in patients with lenticulostriate infarction. Further studies are needed to investigate the temporal relationships of SIG in patients with cerebral infarction.
Source: Frontiers in Neurology - September 20, 2023 Category: Neurology Source Type: research

In reply to the Letter to the Editor regarding: Identifying large vessel occlusion using the hyperdense artery sign in patients treated with mechanical thrombectomy
We sincerely thank Drs. Shunji Mugikura and Naoko Mori for the interest and comments in our article, “Identifying large vessel occlusion using the hyperdense artery sign in patients treated with mechanical thrombectomy”.1
Source: Journal of Stroke and Cerebrovascular Diseases - September 20, 2023 Category: Neurology Authors: Takuya Saito, Ryo Itabashi, Kazutaka Uchida, Yuichi Kawabata, Shota Igasaki, Kazuhiko Sato, Tomohiro Chiba, Takeshi Morimoto, Yukako Yazawa Tags: Letter to the Editor Source Type: research

Before juvenile stroke can be attributed to MYH11 variants, alternative etiologies and pathophysiologies must be adequately ruled out
We read with interest the article by Raghuram et  al. on a 12 year-old female who developed severe ischemic stroke (NIHSS 16) due to right proximal middle cerebral artery (MCA) occlusion [1]. Despite thrombolysis and thrombectomy, the patient's recovery was incomplete [1]. The cause of the occlusion was attributed to a focal dissection of the MCA due to the variant IVS32G>A in MYH11, which was also found in the maternal grandmother, mother, older sister, and a maternal cousin, two of whom had aortic dissection in the past [1].
Source: Journal of Stroke and Cerebrovascular Diseases - September 20, 2023 Category: Neurology Authors: Josef Finsterer Tags: Letter to the Editor Source Type: research

Renal Dysfunction Among Stroke Patients, Hospital Based Cross Sectional Study, Addis Ababa, Ethiopia, 2021
Conclusion: Renal  dysfunction is a frequent comorbidity in patients who are admitted with the diagnosis of acute stroke and had a higher mortality rate  than stroke patients with normal renal function. 
Source: Ethiopian Journal of Health Development - September 20, 2023 Category: African Health Authors: Lissane Seifu, Yonas Gashaye, Melaku Taye Source Type: research

Combined coronary and carotid artery disease: what to operate on first? or both at the same time?
Heart disease and stroke rank amongst the top four leading causes of death in the United States.1 Studies have demonstrated a positive correlation between the two, even suggesting that carotid artery disease may predict the presence of coronary artery disease (CAD).2,3 In fact, some have found that the prevalence of carotid artery stenosis (CAS) in those undergoing coronary artery bypass grafting (CABG) may be as high as 8-14%.4 Despite such co-existence, there remains no clear consensus Guidelines for revascularization in patients with co-existing CAD and CAS.
Source: Journal of Cardiothoracic and Vascular Anesthesia - September 20, 2023 Category: Anesthesiology Authors: Sherman Yu, Mark A. Chaney Tags: Case Conference Source Type: research

A nomogram predicts early neurological deterioration after mechanical thrombectomy in patients with ischemic stroke
DiscussionOur study established and validated a nomogram to stratify the risk of END before mechanical embolectomy and identify high-risk patients, who should be more cautious when making clinical decisions.
Source: Frontiers in Neurology - September 20, 2023 Category: Neurology Source Type: research

Case report: Retrograde endovascular recanalization of vertebral artery occlusion with non-tapered stump via the deep cervical collateral
ConclusionAntegrade endovascular recanalization of VA occlusion with a non-tapered stump is a challenge. The retrograde endovascular method via the cervical collateral may be an alternative for this type of VA occlusion, which requires further exploration.
Source: Frontiers in Neurology - September 20, 2023 Category: Neurology Source Type: research

How To Avoid China ’ s Medicine Monopoly
I want to share a shocking statistic with you… Around 80% of all the pharmaceuticals sold in America — both prescription and over-the-counter — are manufactured in China. I’m talking about drugs for Parkinson’s and Alzheimer’s, blood pressure and blood thinners, diuretics, aspirin, antibiotics, and a big chunk of the world’s insulin and diabetes drugs — just to name a few.1 We don’t even make penicillin anymore. The last penicillin plant in the U.S. closed its doors in 2004. Americans who rely on medicine are now almost entirely at the mercy of a country whose relations with the U.S. have become more ...
Source: Al Sears, MD Natural Remedies - September 19, 2023 Category: Complementary Medicine Authors: Jacob Tags: Health Source Type: news

FXI Inhibitor Cuts Bleeds in Afib; COAPT Extends to Real World; AI Stroke Triage
(MedPage Today) -- People who were prone to needing dentures tended to also be at higher risk of cardiometabolic disease. (European Journal of Preventive Cardiology) Early real-world experience at a Dutch lipid clinic suggests smaller LDL cholesterol...
Source: MedPage Today Cardiovascular - September 19, 2023 Category: Cardiology Source Type: news

De-escalation from ticagrelor to clopidogrel in patients with acute myocardial infarction: the TALOS-AMI HBR substudy
CONCLUSIONS: In stabilised acute myocardial infarction patients, unguided de-escalation from ticagrelor to clopidogrel was associated with a lower rate of net adverse clinical outcomes irrespective of HBR status. The effect of de-escalation of P2Y12 inhibition on reducing haemorrhagic events was greater in patients with HBR.PMID:37724337 | DOI:10.4244/EIJ-D-23-00427
Source: EuroIntervention - September 19, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Min Chul Kim Sung Gyun Ahn Kyung Hoon Cho Doo Sun Sim Young Joon Hong Ju Han Kim Myung Ho Jeong Jun-Won Lee Young-Jin Youn Hee-Yeol Kim Ki-Dong Yoo Doo-Soo Jeon Eun-Seok Shin Young-Hoon Jeong Kiyuk Chang Youngkeun Ahn Source Type: research

The hemodynamic interplay between pulmonary ischemia-reperfusion injury and right ventricular function in lung transplantation: A translational porcine model
In conclusion, we demonstrate a delicate balance between development of pulmonary ischemia-reperfusion injury and right ventricular function during lung transplantation. Furthermore, we provide a physiological basis for potential benefit of extracorporeal life support technology.PMID:37724349 | DOI:10.1152/ajplung.00281.2022
Source: American Journal of Physiology. Lung Cellular and Molecular Physiology - September 19, 2023 Category: Cytology Authors: Michaela Orlitov á Tom Verbelen Anna E Frick Arno Vanstapel Dieter Van Beersel Sofie Ordies Jan Van Slambrouck Janne Kaes Jin Xin Walter Coudyzer Stijn E Verleden Geert M Verleden Bart M Vanaudenaerde Dirk E Van Raemdonck Robin Vos Laurens J Ceulemans Pi Source Type: research

Long-term outcomes after conservative and EDAS treatment for 111 elderly patients with moyamoya disease: longitudinal and cross-sectional study
CONCLUSIONS: The postoperative long-term stroke rate among elderly patients with MMD was lower in the EDAS group than in the conservative treatment group. Long-term stroke events were associated with advanced age, aneurysm, and initial ischemia after conservative treatment and only initial hemorrhage after EDAS.PMID:37724788 | DOI:10.3171/2023.7.JNS231060
Source: Journal of Neurosurgery - September 19, 2023 Category: Neurosurgery Authors: Jing-Jie Li Xiao-Peng Wang Qian-Nan Wang Xiang-Yang Bao Qing-Bao Guo Zi-Qing Kong Gan Gao Min-Jie Wang Si-Meng Liu He-Guan Fu Qian Zhang Lian Duan Source Type: research