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Manage your risk of carotid artery disease
Carotid artery disease occurs when the blood vessels supplying your brain and head, known as carotid arteries, are damaged or blocked by fatty deposits. These deposits contain cholesterol that organizes as a plaque, which clogs or blocks the carotid arteries. This is similar to coronary artery disease, which reduces blood flow to your heart. This blockage in blood vessels increases your risk of stroke — a medical emergency that occurs when the blood supply to the brain is…
Source: News from Mayo Clinic - September 19, 2023 Category: Databases & Libraries Source Type: news
Clinical characteristics, outcomes and risk factors for mortality in hospitalized diabetes and chronic kidney disease patients after COVID-19 infection following widespread vaccination
ConclusionsThese findings highlight the critical importance of identifying and managing comorbid risk factors for COVID-19, especially among the elderly, in order to optimize clinical outcomes, even after COVID-19 vaccination.
Source: Journal of Endocrinological Investigation - September 19, 2023 Category: Endocrinology Source Type: research
AHA Reviews Impact of Aggressive LDL Lowering on the Brain AHA Reviews Impact of Aggressive LDL Lowering on the Brain
The preponderance of evidence does not support the conclusion that aggressive cholesterol-lowering is associated with cognitive impairment or hemorrhagic stroke, a new statement concludes.Medscape Medical News
Source: Medscape FamilyMedicine Headlines - September 18, 2023 Category: Primary Care Tags: Cardiology News Source Type: news
Multi-Channel FES Gait Rehabilitation Assistance System Based on Adaptive sEMG Modulation
This study proposes a multi-channel FES gait rehabilitation assistance system based on adaptive myoelectric modulation. The proposed system collects sEMG of the vastus lateralis muscle on the non-affected side to predict the sEMG values of four targeted lower-limb muscles on the affected side using a bidirectional long short-term memory (BILSTM) model. Next, the proposed system modulates the real-time FES output frequency for four targeted muscles based on the predicted sEMG values to provide muscle force compensation. Fifteen healthy subjects were recruited to participate in an offline model-building experiment conducted ...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - September 18, 2023 Category: Neuroscience Source Type: research
Blood biomarker changes following therapeutic hypothermia in ischemic stroke
ConclusionAlthough the exact roles of MMP3, FABP, and IL-8 in hypothermia-treated stroke patients are not known, further exploration is needed to confirm their roles in brain ischemia.
Source: Brain and Behavior - September 18, 2023 Category: Neurology Authors: Elena Pal à,
Anna Penalba,
Alejandro Bustamante,
Teresa García‐Berrocoso,
Marcel Lamana‐Vallverdú,
Christian Meisel,
Andreas Meisel,
H. Bart van der Worp,
Malcolm R Macleod,
Bernd Kallmünzer,
Stefan Schwab,
Joan Montaner Tags: BRIEF REPORT Source Type: research
Cerebral embolic protection during transcatheter heart interventions
EuroIntervention. 2023 Sep 18;19(7):549-570. doi: 10.4244/EIJ-D-23-00166.ABSTRACTStroke remains a devastating complication of transcatheter aortic valve replacement (TAVR), with the incidence of clinically apparent stroke seemingly fixed at around 3% despite TAVR's significant evolution during the past decade. Embolic showers of debris (calcium, atheroma, valve material, foreign material) are captured in the majority of patients who have TAVR using a filter-based cerebral embolic protection device (CEPD). Additionally, in systematic brain imaging studies, the majority of patients receiving TAVR exhibit new cerebral lesions...
Source: EuroIntervention - September 18, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Victor Alfonso Jimenez Diaz Samir R Kapadia Axel Linke Darren Mylotte Alexandra J Lansky Eberhard Grube Magnus Settergren Rishi Puri Source Type: research
Vasculitis associated with adenosine deaminase 2 deficiency: at the crossroads between Beh çet's disease and autoinflammation. A viewpoint
Reumatismo. 2023 Sep 18;75(3). doi: 10.4081/reumatismo.2023.1578.ABSTRACTAdenosine deaminase 2 deficiency (DADA2) is a rare monogenic vasculopathy caused by loss-of-function homozygous or compound heterozygous mutations in ADA2, formerly CECR1 (cat eye syndrome chromosome region 1) gene. The DADA2 phenotype is widely heterogeneous, and patients may present with fever, weight loss, livedo reticularis/racemosa, digital ischemia, cutaneous ulceration, peripheral neuropathy, abdominal pain, bowel perforation, and portal or nephrogenic hypertension. More specific manifestations include early-onset ischemic or hemorrhagic stroke...
Source: Reumatismo - September 18, 2023 Category: Rheumatology Authors: A Colangelo F Tromby G Cafaro R Gerli E Bartoloni C Perricone Source Type: research
Perceived Level of Life Enjoyment and Risk of Developing Disabling Dementia: The Japan Public Health Center-Based Study
DISCUSSION: A higher level of life enjoyment was associated with a lower risk of disabling dementia, particularly in the low-medium mental stress group. This finding suggests the importance of having life enjoyment by managing mental stress for reducing risk of disabling dementia.PMID:37718836 | DOI:10.1093/geronb/gbad129
Source: Cancer Control - September 18, 2023 Category: Cancer & Oncology Authors: Tomokazu Tajima Ai Ikeda Takeshi Tanigawa Hiroyasu Iso Kazumasa Yamagishi Takumi Matsumura Nobufumi Yasuda Manami Inoue Shoichiro Tsugane Norie Sawada Japan Public Health Center –Based Study Group Source Type: research
Single-center experience of endovascular treatment for patients with progressive posterior circulation cerebral infarction exceeding 24 h
CONCLUSION: In patients with progressive posterior circulation cerebral infarction caused by vertebral basilar artery occlusion, ET is effective and safe even if the time from onset to puncture exceeds 24 h.PMID:37719319 | PMC:PMC10505061 | DOI:10.2478/abm-2023-0046
Source: Biomed Res - September 18, 2023 Category: Research Authors: Guangfeng Zhao Xiongjun He Yajie Liu Liang Zhang Kaifeng Li Source Type: research
Atherosclerosis as a Risk Factor for IBD: A Population-Based Case-Control Study
CONCLUSIONS: A history of an atherosclerotic-related condition is associated with increased odds of developing IBD, particularly among older adults. Future studies should investigate whether drugs targeting atherosclerotic-related inflammation may prevent IBD in higher-risk individuals.PMID:37721310 | DOI:10.14309/ajg.0000000000002502
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Adam S Faye Jordan Axelrad Jiangwei Sun Jonas Halfvarson Jonas S öderling Ola Ol én Jonas F Ludvigsson Source Type: research
Understanding the Link Between Adult Asthma and Coronary Artery Disease: A Narrative Review
Cureus. 2023 Aug 17;15(8):e43621. doi: 10.7759/cureus.43621. eCollection 2023 Aug.ABSTRACTAsthma is a common pathology worldwide that occurs due to chronic inflammation of the respiratory airways. Persistent pulmonary inflammation leads to low-grade systemic inflammation, influencing blood vessels and triggering coronary artery disease (CAD) events. This review's objectives include discussing the susceptible population for CAD, the mechanism underlying CAD creation in asthma patients, the characteristics of asthma, and the influence of anti-asthmatic medications on CAD development. Adult-onset asthma is strongly linked to ...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Vasudha S Garg Mihir H Sojitra Tyagi J Ubhadiya Nidhi Dubey Karan Shah Siddharth Kamal Gandhi Priyansh Patel Source Type: research
A 96-wells fluidic system for high-throughput screenings under laminar high wall shear stress conditions
Microsyst Nanoeng. 2023 Sep 15;9:114. doi: 10.1038/s41378-023-00589-x. eCollection 2023.ABSTRACTThe ability of endothelial cells to respond to blood flow is fundamental for the correct formation and maintenance of a functional and hierarchically organized vascular network. Defective flow responses, in particular related to high flow conditions, have been associated with atherosclerosis, stroke, arteriovenous malformations, and neurodegenerative diseases. Yet, the molecular mechanisms involved in high flow response are still poorly understood. Here, we described the development and validation of a 96-wells fluidic system, w...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Catarina Gon çalves Fonseca V ânia Silvério David Barata Wolfgang Giese Holger Gerhardt Susana Cardoso Claudio Areias Franco Source Type: research
Role of TRPV1 in electroacupuncture-mediated signal to the primary sensory cortex during regulation of the swallowing function
CONCLUSION: The TRPV1 at CV23 after EA treatment might play a key role in mediating local blood perfusion but was not involved in transferring EA signals to the central nervous system (CNS). These findings collectively suggested that TRPV1 may be one of the important regulators involved in the mechanism of EA treatment for improving swallowing function in PSD.PMID:37718934 | DOI:10.1111/cns.14457
Source: CNS Neuroscience and Therapeutics - September 18, 2023 Category: Neuroscience Authors: Si Yuan Bo Qiu Ying Liang Bing Deng Jing Xu Xiaorong Tang Junshang Wu Sheng Zhou Zeli Li Hongzhu Li Qiuping Ye Lin Wang Shuai Cui Chunzhi Tang Wei Yi Lulu Yao Nenggui Xu Source Type: research
Neurophysiological characterization of stroke recovery: A longitudinal TMS and EEG study
CONCLUSION: Our results demonstrate prominent clinical implications for individualized stroke rehabilitation based on both functional integrity of the ipsilesional corticomotor pathway and motor function.PMID:37718708 | DOI:10.1111/cns.14471
Source: CNS Neuroscience and Therapeutics - September 18, 2023 Category: Neuroscience Authors: Qian Ding Jixiang Chen Shunxi Zhang Songbin Chen Xiaotong Li Yuan Peng Yujie Chen Junhui Chen Kang Chen Guiyuan Cai Guangqing Xu Yue Lan Source Type: research
Reliability and validity of the supine-to-stand test in people with stroke
CONCLUSION: The supine-to-stand test is a reliable, sensitive, specific and easy-to-administer clinical test for assessing the supine-to-stand ability of people with stroke.PMID:37721097 | DOI:10.2340/jrm.v55.12372
Source: Journal of Rehabilitation Medicine - September 18, 2023 Category: Rehabilitation Authors: Shamay S M Ng Peiming Chen Tony C W Chan Cherry H L Chang Regen H Y Cheng Kylie K L Chow Alex F M Yeung Tai-Wa Liu Lily Y W Ho Jerry W F Yeung Richard H Xu Mimi M Y Tse Source Type: research
