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Condition: Spinal Cord Injury

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Total 1255 results found since Jan 2013.

Validation of the NIH Toolbox in Individuals with Neurologic Disorders.
Conclusions: Data provide support for the validity of the NIHTB in individuals with neurologic conditions. PMID: 28334392 [PubMed - as supplied by publisher]
Source: Archives of Clinical Neuropsychology - March 18, 2017 Category: Psychiatry & Psychology Authors: Carlozzi NE, Goodnight S, Casaletto KB, Goldsmith A, Heaton RK, Wong AW, Baum CM, Gershon R, Heinemann AW, Tulsky DS Tags: Arch Clin Neuropsychol Source Type: research

Fundamental hemodynamic mechanisms mediating the response to myocardial ischemia in conscious paraplegic mice: cardiac output versus peripheral resistance
Abstract Autonomic dysfunction, a relative sedentary lifestyle, a reduced muscle mass and increased adiposity leads to metabolic abnormalities that accelerate the development of coronary artery disease (CAD) in individuals living with spinal cord injury (SCI). An untoward cardiac incident is related to the degree of CAD, suggesting that the occurrence of a significant cardiac event is significantly higher for individuals with SCI. Thus, understanding the fundamental hemodynamic mechanisms mediating the response to myocardial ischemia has the potential to positively impact individuals and families living with SCI. According...
Source: Physiological Reports - March 29, 2017 Category: Physiology Authors: Heidi L. Lujan, Stephen E. DiCarlo Tags: Original Research Source Type: research

One-stage hybrid procedure for distal aortic arch disease: mid-term experience at a single center.
Conclusions: The one-stage hybrid procedure provides acceptable mid-term results with good mid-term patency of extra-anatomic bypass. Strict selection of patients suitable for hybrid repair can effectively improve the survival rate and reduce the incidence of complications. At the same time, close follow-up patients should receive close long-term follow-up after hybrid procedure. PMID: 33447400 [PubMed]
Source: Journal of Thoracic Disease - January 17, 2021 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Content validity of the Brief and Comprehensive ICF Core Sets for common disabling conditions in a developing country
The International Classification of Functioning, Disability and Health (ICF) features associated tools, the Brief and Comprehensive ICF Core Sets. These are designed to be universally applicable, but have limited evidence of content validity (i.e. comprehensiveness and relevance) in low income, non-Western countries. In this cross-sectional study, we aimed to assess the content validity of the ICF Core Sets in Nepal. We interviewed 161 participants with stroke, spinal cord injury (SCI), chronic obstructive pulmonary disease (COPD), and musculoskeletal conditions and asked them to identify activities they had difficulty per...
Source: International Journal of Rehabilitation Research - May 20, 2021 Category: Rehabilitation Tags: Original Articles Source Type: research

Reliability and Validity of the Composite Activity-Related Fall Risk Scale
ConclusionThe CARFS is a reliable and valid tool for measuring fall risk in older people and persons with stroke or spinal cord injury.
Source: Frontiers in Neurology - March 22, 2022 Category: Neurology Source Type: research

Usability test of a hand exoskeleton for activities of daily living: an example of user-centered design.
CONCLUSIONS: The findings demonstrate that although Handexos meets the initial functional requirements and underlines the potential for assisting SCI and post-stroke subjects in ADLs, several aspects such as mechanical complexity and low adaptability to different hand sizes need to be further addressed. Implications for Rehabilitation Wearable robotics devices could improve the activities of daily living in patients with spinal cord injury or stroke. They could be a tool for rehabilitation of the upper limb. Further usability tests to improve this type of tools are recommended. PMID: 26376019 [PubMed - as supplied by publisher]
Source: Disability and Rehabilitation. Assistive Technology. - September 16, 2015 Category: Rehabilitation Authors: Almenara M, Cempini M, Gómez C, Cortese M, Martín C, Medina J, Vitiello N, Opisso E Tags: Disabil Rehabil Assist Technol Source Type: research

Inflammation and neural repair after ischemic brain injury
Publication date: Available online 19 October 2018Source: Neurochemistry InternationalAuthor(s): Seiichiro Sakai, Takashi ShichitaAbstractStroke causes neuronal cell death and destruction of neuronal circuits in the brain and spinal cord. Injury to the brain tissue induces sterile inflammation triggered by the extracellular release of endogenous molecules, but cerebral inflammation after stroke is gradually resolved within several days. In this pro-resolving process, inflammatory cells adopt a pro-resolving or repairing phenotype in the injured brain, activating endogenous repairing programs. Although the mechanisms involv...
Source: Neurochemistry International - October 20, 2018 Category: Neuroscience Source Type: research

Exosomes in Acquired Neurological Disorders: New Insights into Pathophysiology and Treatment
AbstractExosomes are endogenous nanovesicles that play critical roles in intercellular signaling by conveying functional genetic information and proteins between cells. Exosomes readily cross the blood-brain barrier and have promise as therapeutic delivery vehicles that have the potential to specifically deliver molecules to the central nervous system (CNS). This unique feature also makes exosomes attractive as biomarkers in diagnostics, prognostics, and therapeutics in the context of multiple significant public health conditions, including acquired neurological disorders. The purpose of this review is to summarize the sta...
Source: Molecular Neurobiology - October 26, 2018 Category: Neurology Source Type: research

Ekso Bionics Steps Up to Develop Exoskeleton Market in Asia
China is expected to have 30 million stroke patients by 2030, and many of those patients will have some degree of disability. And yet, the stroke and spinal cord rehabilitation industry in China is not as developed as it is in the United States. A new joint venture between Ekso Bionics, Zhejiang Youchuang Venture Capital Investment (ZYVC) and Zhejiang Silicon Paradise Asset Management Group could change that. "This joint venture is a transformative opportunity both for Ekso Bionics and for the millions of Chinese stroke and spinal cord injury patients who currently have limited access to advanced rehabilitation...
Source: MDDI - January 30, 2019 Category: Medical Devices Authors: MDDI Staff Tags: Orthopedics Source Type: news

Exploring Training Effect in 42 Human Subjects Using a Non-invasive Sensorimotor Rhythm Based Online BCI
Conclusion In this study, we analyzed a pooled dataset consisting of 42 subjects’ three BCI training sessions. The behavioral performance results showed that there was a significant increase of BCI PVC accuracy (p = 0.004) and a marginal significant improvement of ITR (p = 0.05) in the third training session compared to the first session. No other significant difference of behavioral measures such as group average abort rate or feedback duration was found across the training sessions. Further analysis on the group average R2 value indicated that there was a significant difference of the R2 value on the first traini...
Source: Frontiers in Human Neuroscience - April 16, 2019 Category: Neuroscience Source Type: research

Learning to Walk Again
When someone suffers a stroke, he or she often loses some mobility, and some 60 percent of survivors are left with lower-limb deficits. “They usually have one leg that's more impaired than the other leg, and then they undergo rehabilitation and physical therapy. And often they don't fully recover,” said Conor Walsh, professor of engineering and applied sciences at the John A. Paulson Harvard School of Engineering and Applied Sciences and a core faculty member at the Wyss Institute for Biologically Inspired Engineering, in an interview with MD+DI. But a new device called ReSto...
Source: MDDI - April 17, 2019 Category: Medical Devices Authors: Susan Shepard Tags: Design Source Type: news

Glutamate Transport and Preterm Brain Injury
Silvia Pregnolato1*, Elavazhagan Chakkarapani1, Anthony R. Isles2 and Karen Luyt1 1Department of Neonatal Neurology, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom 2Behavioural Genetics Group, MRC Centre for Neuropsychiatric Genetics and Genomics, School of Medicine, Cardiff University, Cardiff, United Kingdom Preterm birth complications are the leading cause of child death worldwide and a top global health priority. Among the survivors, the risk of life-long disabilities is high, including cerebral palsy and impairment of movement, cognition, and beh...
Source: Frontiers in Physiology - April 23, 2019 Category: Physiology Source Type: research

Early and late outcomes of aortic surgery under hypothermic circulatory arrest in the elderly: a single center study.
CONCLUSIONS: Aortic surgery with circulatory arrest in the elderly demonstrated favorable early and late results when compared with younger individuals, with an acceptable operative risk even under emergency conditions, and should not be denied only because of the chronological age of the patients. PMID: 31599143 [PubMed - as supplied by publisher]
Source: The Journal of Cardiovascular Surgery - October 3, 2019 Category: Cardiovascular & Thoracic Surgery Authors: Mauduit M, Anselmi A, Tomasi J, Belahj Soulami R, Roisné A, Flecher E, Rouzé S, Verhoye JP Tags: J Cardiovasc Surg (Torino) Source Type: research

Handrim Wheelchair Propulsion Training Effect on Overground Propulsion Using Biomechanical Real-Time Visual Feedback
Conclusions: Long-term wheelchair users in both intervention groups significantly improved many aspects of their propulsion technique immediately after training and 3 months from baseline. Furthermore, training with a low-cost instructional video and slide presentation was an effective training tool alone.
Source: Archives of Physical Medicine and Rehabilitation - September 28, 2012 Category: Rehabilitation Authors: Ian M. Rice, Ryan T. Pohlig, Jerri D. Gallagher, Michael L. Boninger Tags: Featured Articles Source Type: research

Cardiovascular Response of Individuals With Spinal Cord Injury to Dynamic Functional Electrical Stimulation Under Orthostatic Stress
In this pilot study, we examined how effectively functional electrical stimulation (FES) and passive stepping mitigated orthostatic hypotension in participants with chronic spinal cord injury (SCI). While being tilted head-up to 70° from the supine position, the participants underwent four 10-min conditions in a random sequence: 1) no intervention, 2) passive stepping, 3) isometric FES of leg muscles, and 4) FES of leg muscles combined with passive stepping. We found that FES and passive stepping independently mitigated a decrease in stroke volume and helped to maintain the mean blood pressure. The effects of FES on...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - January 1, 2013 Category: Neuroscience Source Type: research