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Nutrition: Ginkgo
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Total 93 results found since Jan 2013.
Traditional medicine in China for ischemic stroke: bioactive components, pharmacology, and mechanisms
J Integr Neurosci. 2022 Jan 28;21(1):26. doi: 10.31083/j.jin2101026.ABSTRACTIschemic stroke is an acute cerebrovascular disease and the third most common cause of death after ischemic heart disease. Increasing attention is being paid to finding effective treatments through traditional medicine. Thus, studying the traditional medicine for the treatment of ischemic stroke is of great importance. Traditional medicine in China includes traditional Chinese medicine (TCM) and other ethnic medicines, which is rich in variety and resources. This review first introduces the treatment mechanisms associated with ischemic stroke, such...
Source: Journal of Integrative Neuroscience - February 15, 2022 Category: Neuroscience Authors: Min Xu Rui-Xia Wu Xiao-Li Li Yi-Shen Zeng Jia-Yang Liang Ke Fu Yuan Liang Zhang Wang Source Type: research
Folium < em > Ginkgo < /em > extract and tetramethylpyrazine sodium chloride injection (Xingxiong injection) protects against focal cerebral ischaemia/reperfusion injury via activating the Akt/Nrf2 pathway and inhibiting NLRP3 inflammasome activation
CONCLUSIONS: Xingxiong injection prevents cerebral ischaemia/reperfusion injury via activating the Akt/Nrf2 pathway and inhibiting NLRP3 inflammasome. These findings provide experimental evidence for clinical use of drugs in the treatment of ischaemic stroke.PMID:35060427 | PMC:PMC8786246 | DOI:10.1080/13880209.2021.2014895
Source: Pharmaceutical Biology - January 21, 2022 Category: Drugs & Pharmacology Authors: Ting Zhu Bin-Yu Fang Xiang-Bao Meng Shu-Xia Zhang Hong Wang Ge Gao Fei Liu Yu Wu Jin Hu Gui-Bo Sun Xiao-Bo Sun Source Type: research
The Clinical Efficacy of < em > Ginkgo biloba < /em > Leaf Preparation on Ischemic Stroke: A Systematic Review and Meta-Analysis
CONCLUSION: The existing clinical evidence shows that GLP has a good therapeutic effect on patients with ischemic stroke and can improve their hemorheology indices. In addition, GLP is shown to be relatively safe.PMID:34925528 | PMC:PMC8677404 | DOI:10.1155/2021/4265219
Source: Evidence-based Complementary and Alternative Medicine - December 20, 2021 Category: Complementary Medicine Authors: Shuang Zhao Hong Zheng Yawei Du Runlei Zhang Peilin Chen Rong Ren Shengxian Wu Source Type: research
Balance Training With Vibrotactile Neurofeedback and Ginkgo Biloba Extract in Age-Related Vertigo
Conclusion: Over 12 weeks, the combination of balance training with VNF and Ginkgo biloba dry extract EGb 761 reached a clinically relevant improvement of age-related vertigo and dizziness with a good pharmacological safety profile.
Source: Frontiers in Neurology - November 30, 2021 Category: Neurology Source Type: research
Shenmayizhi Formula Combined with Ginkgo Extract Tablets for the Treatment of Vascular Dementia: A Randomized, Double-Blind, Controlled Trial.
Authors: Zhang H, Cao Y, Pei H, Wang H, Ma L, Wang Z, Diao X, Yang Y, Liu N, Wei Y, Li H
Abstract
Shenmayizhi formula (SMYZF) has been shown to have an effect on vascular dementia (VaD) in previous studies. The aim of this study was to evaluate whether a combination of SMYZF with Ginkgo extract tablets improves mild-to-moderate VaD. In this 12-week, randomized, double-blind, controlled study, we randomly assigned 196 patients with VaD (aged 50-85 years) to either the SMYZF group (n = 98) or the Ginkgo group (n = 98). All patients received Ginkgo extract tablets as a basic treatment, while the SMYZF group al...
Source: Evidence-based Complementary and Alternative Medicine - August 14, 2020 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Molecules, Vol. 25, Pages 2719: Hormesis and Ginseng: Ginseng Mixtures and Individual Constituents Commonly Display Hormesis Dose Responses, Especially for Neuroprotective Effects
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This paper demonstrates that ginseng mixtures and individual ginseng chemical constituents commonly induce hormetic dose responses in numerous biological models for endpoints of biomedical and clinical relevance, typically providing a mechanistic framework. The principal focus of ginseng hormesis-related research has been directed toward enhancing neuroprotection against conditions such as Alzheimer&rsquo;s and Parkinson&rsquo;s Diseases, stroke damage, as well as enhancing spinal cord and peripheral neuronal damage repair and reducing pain. Ginseng was also shown to reduce symptoms of diabetes, prev...
Source: Molecules - June 10, 2020 Category: Chemistry Authors: Calabrese Tags: Review Source Type: research
Chip-based serum proteomics approach to reveal the potential protein markers in the sub-acute stroke patients receiving the treatment of Ginkgo Diterpene Lactone Meglumine Injection
Publication date: Available online 13 May 2020Source: Journal of EthnopharmacologyAuthor(s): Qiru Fan, Jing Zhou, Yilin Wang, Tao Xi, Hongyue Ma, Zhenzhong Wang, Wei Xiao, Qiu Liu
Source: Journal of Ethnopharmacology - May 14, 2020 Category: Drugs & Pharmacology Source Type: research
Shuxuening injection facilitates neurofunctional recovery via down-regulation of G-CSF-mediated granulocyte adhesion and diapedesis pathway in a subacute stroke mouse model.
This study was to investigate whether SXNI can improve the prognosis of stroke at a subacute phase. Mice with cerebral ischemia-reperfusion injury (CIRI) were established by middle cerebral artery occlusion (MCAO), and drugs or saline were injected by the tail vein every 12 h after reperfusion. The therapeutic effect of SXNI was evaluated by survival rate, modified neurologic severity scores (mNSS), open-field test, locomotive gait patterns, cerebral infarction volume, brain edema and histopathological changes. Subsequently, a combined method of RNA-seq and Ingenuity® Pathway Analysis (IPA) was performed to identify key t...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - May 13, 2020 Category: Drugs & Pharmacology Authors: Li Z, Xiao G, Lyu M, Wang Y, He S, Du H, Wang X, Feng Y, Zhu Y Tags: Biomed Pharmacother Source Type: research
Efficacy and Safety of Ginkgo biloba in Patients with Acute Ischemic Stroke: A Systematic Review and Meta-Analysis.
Abstract
Ginkgo biloba and its extract have been suggested to have a neuroprotective role in patients with acute ischemic stroke. We aimed to examine the efficacy and safety of Ginkgo biloba use in patients with acute ischemic stroke. We searched seven databases for randomized controlled studies examining the use of Ginkgo biloba in patients with acute ischemic stroke. Relevant studies were retrieved, screened, and data were extracted independently by two reviewers. Random effects meta-analyses were performed to evaluate the efficacy and safety outcomes of Ginkgo biloba. We subsequently assessed the certainty of e...
Source: The American Journal of Chinese Medicine - April 29, 2020 Category: Complementary Medicine Authors: Chong PZ, Ng HY, Tai JT, Lee SWH Tags: Am J Chin Med Source Type: research
Ginkgol Biloba extract as an adjunctive treatment for ischemic stroke: A systematic review and meta-analysis of randomized clinical trials
Conclusions:
GBE appears to improve neurological function and dependence compared with conventional therapy for ischemic stroke at different stages and appears generally safe for clinical application. The lack of improvement in recurrence rate was confirmed by trial sequential analysis. Due to the generally weak evidence, further large, rigorous trials are warranted.
Source: Medicine - January 1, 2020 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research
Efficacy and Safety of Ginkgo Leaf Extract and Dipyridamole Injection for Ischemic Stroke: A Systematic Review and Meta Analysis
Conclusion: Evidence from the meta-analysis suggested that the combination of conventional treatments and GDI is safe and more effective in treating ischemic stroke than conventional treatments alone. Therefore, GDI mediated therapy could be recommended as an adjuvant treatment for ischemic stroke.
Source: Frontiers in Pharmacology - December 3, 2019 Category: Drugs & Pharmacology Source Type: research
Efficacy and safety of Shenmayizhi decoction as an adjuvant treatment for vascular dementia: Study protocol for a randomized controlled trial
This study will provide evidences to evaluate the efficacy and safety of SMYZD in combination with GBEs in treatment of VaD, as well as the adjuvant role of SMYZD in combination.
Trial is registered at Chinese Clinical Trial Registry:
ChiCTR1800017359.
Source: Medicine - December 1, 2019 Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research
Ginkgo diterpene lactones inhibit cerebral ischemia/reperfusion induced inflammatory response in astrocytes via TLR4/NF-κB pathway in rats
Conclusions:In summary, GDL attenuate cerebral ischemic injury, inhibits platelet aggregation and astrocytes activation. The anti-inflammatory activity might be associated with the downregulation of TLR4/NF-κB signal pathway. Our present findings provide an innovative insight into the novel treatment of GDL in ischemic stroke therapy.Graphical abstract
Source: Journal of Ethnopharmacology - October 31, 2019 Category: Drugs & Pharmacology Source Type: research
