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Nutrition: Ginkgo
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Total 93 results found since Jan 2013.
Efficacy of ginkgo biloba extract as augmentation of venlafaxine in treating post-stroke depression
Source: Neuropsychiatric Disease and Treatment - September 2, 2019 Category: Psychiatry Tags: Neuropsychiatric Disease and Treatment Source Type: research
Interactions between clopidogrel and traditional Chinese medicine
AbstractThe use of traditional Chinese medicine (TCM) has obtained more and more acceptance all over the world due to its multi-target and multi-level function characteristics. Clopidogrel is a major therapeutic option to reduce atherothrombotic events in patients with acute coronary syndrome, recent myocardial infarction, recent stroke or established peripheral arterial disease. These patients probably take TCM. Are there any interactions between clopidogrel and TCM? Whether TCM will affect the efficacy of clopidogrel or increase the adverse reactions of bleeding? Clarifying this information will help physicians make bett...
Source: Journal of Thrombosis and Thrombolysis - August 29, 2019 Category: Hematology Source Type: research
Ginkgo Flavonol Glycosides or Ginkgolides Tend to Differentially Protect Myocardial or Cerebral Ischemia –Reperfusion Injury via Regulation of TWEAK-Fn14 Signaling in Heart and Brain
In conclusion, our study showed that GFGs and GGs of SXNI tend to differentially protect brain and heart from ischemia–reperfusion (I/R) injuries at least in part by regulating a common TWEAK-Fn14 signaling pathway.
Source: Frontiers in Pharmacology - July 4, 2019 Category: Drugs & Pharmacology Source Type: research
Blood amyloid levels and risk of dementia in the Ginkgo Evaluation of Memory Study (GEMS): A longitudinal analysis.
We examined baseline plasma β-amyloid (Aβ) levels in relationship to incident dementia during a period of 8.5 years in 2840 subjects age >75 years; 2381 were cognitively normal (CN) and 450 mild cognitive impairment.
RESULTS: Increased plasma Aβ1-40 and Aβ1-42 levels were associated with gender (women), age, low education, creatinine levels, history of stroke, and hypertension. CN participants who developed dementia had lower levels of Aβ1-42 and Aβ1-42/Aβ1-40 ratio compared with those who did not. Aβ levels did not predict dementia in mild cognitive impairment participants.
DISCUSSION: There was an inv...
Source: The Journal of Alzheimers Association - July 2, 2019 Category: Psychiatry Tags: Alzheimers Dement Source Type: research
Blood amyloid levels and risk of dementia in the Ginkgo Evaluation of Memory Study (GEMS): A longitudinal analysis
We examined baseline plasma β-amyloid (Aβ) levels in relationship to incident dementia during a period of 8.5 years in 2840 subjects age>75 years; 2381 were cognitively normal (CN) and 450 mild cognitive impairment.ResultsIncreased plasma Aβ1-40 and Aβ1-42 levels were associated with gender (women), age, low education, creatinine levels, history of stroke, and hypertension. CN participants who developed dementia had lower levels of Aβ1-42 and Aβ1-42/Aβ1-40 ratio compared with those who did not. Aβ levels did not predict dementia in mild cognitive impairment participants.DiscussionThere was an inverse association b...
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - June 28, 2019 Category: Geriatrics Source Type: research
Antioxidant effects of ginkgolides and bilobalide against cerebral ischemia injury by activating the Akt/Nrf2 pathway in vitro and in vivo.
In conclusion, GA, GB, GK, and BB significantly inhibited oxidative stress damage caused by cerebral ischemia reperfusion. Compared with GA, GK, and BB, GB exerts the strongest antioxidant stress effects against ischemic stroke. Moreover, ginkgolides and BB upregulated the levels of antioxidant proteins through mediating the Akt/Nrf2 signaling pathway to protect neurons from oxidative stress injury.
PMID: 30815818 [PubMed - as supplied by publisher]
Source: Cell Stress and Chaperones - February 26, 2019 Category: Cytology Authors: Liu Q, Jin Z, Xu Z, Yang H, Li L, Li G, Li F, Gu S, Zong S, Zhou J, Cao L, Wang Z, Xiao W Tags: Cell Stress Chaperones Source Type: research
Effects of ginkgo biloba extract on the cognitive function and expression profile of inflammatory factors in a rat model of hemorrhagic stroke
Hemorrhagic stroke is a major risk factor for cognitive impairment. Our study aimed to measure the effect of ginkgo biloba extract (EGB761) on the cognitive ability and inflammatory expression in hemorrhagic stroke model SD rats and to analyze their relationship. Forty SD rats were divided randomly into an SD group (normal control SD rats), an SD+EGB761 group (normal control SD rats supplemented with 45 mg/kg EGB761), a CO group (hemorrhagic stroke model SD rats using collagenase), and a CO+EGB761 group (hemorrhagic stroke model SD rats supplemented with 45 mg/kg EGB761) consisting of 10 rats, respectively. The Y-elect...
Source: NeuroReport - September 14, 2018 Category: Neurology Tags: Cellular, Molecular and Developmental Neuroscience Source Type: research
Effect of Ginkgo biloba extract-761 on motor functions in permanent middle cerebral artery occlusion rats
ConclusionsEGb 761 could improv motor function especially gait impairments among pMCAO rat model related to the decreased neuronal damage. Therefore, it might be the potential to be explored further as an effective therapeutic drug to treat post stroke motor dysfunctions.Graphical Abstract
Graphical Abstract
Source: Phytomedicine - July 10, 2018 Category: Drugs & Pharmacology Source Type: research
Ginkgo biloba Extract Inhibits Astrocytic Lipocalin-2 Expression and Alleviates Neuroinflammatory Injury via the JAK2/STAT3 Pathway After Ischemic Brain Stroke
Yehao Zhang, Jianxun Liu, Bin Yang, Yongqiu Zheng, Mingjiang Yao, Mingqian Sun, Li Xu, Chengren Lin, Dennis Chang, Fangze Tian
Source: Frontiers in Pharmacology - May 16, 2018 Category: Drugs & Pharmacology Source Type: research
Effect of Ginkgo biloba extract-761 on motor functions in permanent middle cerebral artery occlusion rats
Conclusions EGb 761 could improv motor function especially gait impairments among pMCAO rat model related to the decreased neuronal damage. Therefore, it might be the potential to be explored further as an effective therapeutic drug to treat post stroke motor dysfunctions. Graphical abstract
Source: Phytomedicine - May 9, 2018 Category: Drugs & Pharmacology Source Type: research
Diterpene ginkgolides protect against cerebral ischemia/reperfusion damage in rats by activating Nrf2 and CREB through PI3K/Akt signaling.
This study was designed to investigate the neuroprotective effects of DGMI components against ischemic stroke in vivo and in vitro. Acute cerebral ischemic injury was induced in rats by occlusion of the middle cerebral artery (MCA) for 1.5 h followed by 24 h reperfusion. The rats were treated with DGMI (1, 3 and 10 mg/kg, iv) at the onset of reperfusion and 12 h after reperfusion. Administration of DGMI significantly decreased rat neurological deficit scores, reduced brain infarct volume, and induced protein kinase B (Akt) phosphorylation, which prompted the nuclear translocation of nuclear factor-erythroid 2-related facto...
Source: Acta Pharmacologica Sinica - March 15, 2018 Category: Drugs & Pharmacology Authors: Zhang W, Song JK, Yan R, Li L, Xiao ZY, Zhou WX, Wang ZZ, Xiao W, Du GH Tags: Acta Pharmacol Sin Source Type: research
Medical News Today: Stroke: This herbal extract could improve brain function
Those who have experienced ischemic stroke may benefit from taking a combination of ginkgo biloba extract and aspirin, a new study suggests.
Source: Health News from Medical News Today - December 19, 2017 Category: Consumer Health News Tags: Stroke Source Type: news
Herbal supplement boosts memory in stroke survivors
Researchers from Nanjing University in China found ginkgo bilboa improves stroke sufferers' attention, reflexes and language skills in as little as 12 weeks when taken with aspirin, which thins the blood.
Source: the Mail online | Health - December 19, 2017 Category: Consumer Health News Source Type: news
Ginkgo Biloba Use After Stroke Tied to Less Cognitive Decline
Ginkgo biloba extract plus aspirin is associated with less cognitive decline following stroke, compared with aspirin alone, according to a study in Stroke and Vascular...
Source: Physician's First Watch current issue - December 19, 2017 Category: Primary Care Source Type: news
