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Alzheimer's Death Rate Increased Sharply Over 15 Years (FREE)
By Amy Orciari Herman Edited by Andr é Sofair, MD, MPH, and William E. Chavey, MD, MS The age-adjusted rate of death related to Alzheimer disease increased by over 50% from 1999 to 2014 — from 16.5 … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 26, 2017 Category: Primary Care Source Type: news

Your NEJM Group Today: Upcoming ACGME Changes / Opioid Prescribing & Patient Satisfaction / San Francisco Primary Care Opportunity (FREE)
By the Editors Here's today's offering from NEJM Group:NEJM Knowledge+ Blog: How do you feel … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 26, 2017 Category: Primary Care Source Type: news

AHCA Would Lead to 14 Million More Americans Without Insurance Next Year, CBO Estimates (FREE)
By Kelly Young Edited by Andr é Sofair, MD, MPH, and William E. Chavey, MD, MS The latest version of the American Health Care Act recently passed by the U.S. House of Representatives would leave … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 26, 2017 Category: Primary Care Source Type: news

FDA Approves Cancer Drug Based on Tumor Biomarker, Not Origin (FREE)
By Kelly Young Edited by Susan Sadoughi, MD, and Richard Saitz, MD, MPH, FACP, DFASAM The FDA has approved pembrolizumab (Keytruda) to treat patients who have solid tumors with biomarkers known as microsatellite instability-high (MSI-H) or … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 25, 2017 Category: Primary Care Source Type: news

Cannabidiol Treatment Can Reduce Seizures in Dravet Syndrome (FREE)
By Amy Orciari Herman Edited by Susan Sadoughi, MD, and Richard Saitz, MD, MPH, FACP, DFASAM Adjunctive treatment with cannabidiol — a nonhallucinogenic cannabinoid — may reduce seizure frequency in young people with the Dravet syndrome, according to an industry-funded … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 25, 2017 Category: Primary Care Source Type: news

Your NEJM Group Today: Managing High Drug Prices / Durability of Antiretroviral Therapy / Montana Internist/Hospitalist Opportunities (FREE)
By the Editors Here's what we chose for you from NEJM Group today:NEJM Audio Interview: High … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 25, 2017 Category: Primary Care Source Type: news

FDA Advisers Recommend Approval of Breast Cancer Drug (FREE)
By the Editors An advisory panel recommended on Wednesday that the FDA approve the breast cancer drug neratinib (to be marketed as Nerlynx), … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 25, 2017 Category: Primary Care Source Type: news

Your NEJM Group Today: Scarlet Fever Images / Texting & Teens' Mental Health / Chicago Family Medicine Opportunity (FREE)
By the Editors Take a look at today's offering from NEJM Group:NEJM Clinical Practice Center: Image in Clinical Medicine: A 20-year-old man presented … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 24, 2017 Category: Primary Care Source Type: news

Adding TMP/SMX to Cephalexin May Not Boost Cure Rate in Uncomplicated Cellulitis (FREE)
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM For patients with uncomplicated cellulitis, adding trimethoprim-sulfamethoxazole (TMP/SMX) to cephalexin may offer no benefit beyond cephalexin alone, a JAMA study finds.Some 500 patients older than 12 years seen in … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 24, 2017 Category: Primary Care Source Type: news

WHO Elects New Leader (FREE)
By the Editors The World Health Organization has elected Dr. Tedros Adhanom Gheybreysus to be its … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 24, 2017 Category: Primary Care Source Type: news

Your NEJM Group Today: Scarlett Fever Images / Texting & Teens' Mental Health / Chicago Family Medicine Opportunity (FREE)
By the Editors Take a look at today's offering from NEJM Group:NEJM Clinical Practice Center: Image in Clinical Medicine: A 20-year-old man presented … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 24, 2017 Category: Primary Care Source Type: news

FDA: Restricting MRI Contrast Agents " Not Warranted " (FREE)
By Kristin J. Kelley Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM There isn't evidence to warrant restricting the use of gadolinium-based contrast agents … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 24, 2017 Category: Primary Care Source Type: news

Chondroitin as Effective as Celecoxib for Knee Osteoarthritis (FREE)
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM High-quality chondroitin sulfate is as effective as celecoxib in treating knee osteoarthritis, according to an international trial in the … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 24, 2017 Category: Primary Care Source Type: news

Chocolate Seems to Lower Risk for Atrial Fibrillation, But... (FREE)
By Joe Elia Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM A Danish cohort study finds that moderate intake of chocolate lowers risks for atrial fibrillation (AF); editorialists in Heart, … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 24, 2017 Category: Primary Care Source Type: news

Benralizumab Associated with Less Use of Oral Glucocorticoids in Severe Asthma (FREE)
By Kelly Young Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD The investigational monoclonal antibody benralizumab is associated with reduced oral glucocorticoid use in patients with severe asthma, according to a phase 3, industry-funded … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 22, 2017 Category: Primary Care Source Type: news

Cancer in the Years After Colonoscopy More Common in Black Than White Adults (FREE)
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD Older black adults are more likely than white adults to have colorectal cancer diagnosed in the 5 … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 22, 2017 Category: Primary Care Source Type: news

Long-Term Opioid Treatment Seems Only to Add Complications to Polyneuropathy (FREE)
By Joe Elia Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD Patients taking long-term opioids for polyneuropathy are at increased risk for numerous complications … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 22, 2017 Category: Primary Care Source Type: news

Pravastatin Doesn't Improve Clinical Outcomes in Seniors (FREE)
By Kelly Young Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD Older adults with hypertension and hyperlipidemia might not benefit from taking pravastatin for primary prevention of cardiovascular events, according to an open-label study in … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 22, 2017 Category: Primary Care Source Type: news

FDA Approves First Treatment Specifically for Giant Cell Arteritis (FREE)
By the Editors Subcutaneous tocilizumab (Actemra) is now approved for adults with giant cell arteritis, the FDA announced … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 22, 2017 Category: Primary Care Source Type: news

Your NEJM Group Today: Chronic Pain Rx & Patient-Centered Care / Placebo Effect in the Intellectually Disabled / Massachusetts Primary Care Opportunities (FREE)
By the Editors Here's a sampling of the latest content from NEJM Group:NEJM Catalyst: Expert Article: … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 22, 2017 Category: Primary Care Source Type: news

Addition of Home Noninvasive Ventilation Tied to Fewer Readmissions After COPD Exacerbation (FREE)
By Kelly Young Edited by Susan Sadoughi, MD, and Andr é Sofair, MD, MPH Adding home noninvasive ventilation to home oxygen therapy in certain patients with severe chronic pulmonary obstructive disease (COPD) is associated with lower risk for hospital readmission and death, according … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 22, 2017 Category: Primary Care Source Type: news

Delay in Sepsis Treatment Linked to Higher Mortality Risk (FREE)
By Kelly Young Edited by Susan Sadoughi, MD, and Andr é Sofair, MD, MPH Slower delivery of sepsis treatment is associated with elevated mortality risk, according to a retrospective study published in the New England Journal of Medicine … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 22, 2017 Category: Primary Care Source Type: news

American Urological Assn. Adds 5 More Unnecessary Practices to Choosing Wisely (FREE)
By Kelly Young Edited by Susan Sadoughi, MD, and Andr é Sofair, MD, MPH As part of the Choosing Wisely campaign, the American Urological Association has added five more medical treatments … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 22, 2017 Category: Primary Care Source Type: news

From the Blogs: Constructive Criticism / Curious Case of M184V / View of AHCA from Other Side of Atlantic (FREE)
By the Editors Here's a quick look at what the NEJM Journal Watch bloggers are talking about right now: Insights on Residency Training: Chief resident … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 22, 2017 Category: Primary Care Source Type: news

Your NEJM Group Today: Skin Lesions After Travel Abroad / Exercise Limitation After PE / Kentucky Gastroenterology Opportunity (FREE)
By the Editors Here are today's selections from NEJM Group:NEJM Clinical Practice Center: Case Record: A 27-year-old woman presented with skin … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 22, 2017 Category: Primary Care Source Type: news

Juice Shouldn't Be Offered to Infants, Says Pediatrics Group (FREE)
By Kelly Young Edited by Susan Sadoughi, MD, and Andr é Sofair, MD, MPH The American Academy of Pediatrics has expanded its recommendation against offering juice to all infants 12 months and under because it offers no … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 22, 2017 Category: Primary Care Source Type: news

Most Popular NEJM Group Feature This Week: Leaving Against Medical Advice (FREE)
By the Editors Here's the most clicked-on item we featured from … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 20, 2017 Category: Primary Care Source Type: news

Fennel Tied to Reduction in Menopausal Symptoms (FREE)
By Kelly Young Edited by Andr é Sofair, MD, MPH, and William E. Chavey, MD, MS Use of fennel, a phytoestrogen, is associated with improvements in menopausal symptoms, according to a small … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 19, 2017 Category: Primary Care Source Type: news

Swimming Pool-Associated Cryptosporidiosis Outbreaks Being Reported More Often (FREE)
By Amy Orciari Herman Edited by Andr é Sofair, MD, MPH, and William E. Chavey, MD, MS Reported outbreaks of cryptosporidiosis linked to aquatic facilities doubled between 2014 and 2016, according to an MMWR article.Of 24 states with cryptosporidiosis data … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 19, 2017 Category: Primary Care Source Type: news

Candida Auris, Often Drug-Resistant, Found in 7 States (FREE)
By Amy Orciari Herman Edited by Andr é Sofair, MD, MPH, and William E. Chavey, MD, MS As of mid-May 2017, a total of 77 clinical cases of Candida auris in U.S. health care facilities were reported to the CDC, according to … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 19, 2017 Category: Primary Care Source Type: news

CDC Offers Guidance on 2 vs. 3 Doses of Serogroup B Meningococcal Vaccine (FREE)
By Kelly Young Edited by Andr é Sofair, MD, MPH, and William E. Chavey, MD, MS The CDC has published new recommendations on when to use two or three doses of the MenB-FHbp vaccine (Trumenba) for preventing serogroup B meningococcal disease. … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 19, 2017 Category: Primary Care Source Type: news

Your NEJM Group Today: Letter to a Young Female Physician / Breast-Feeding & Endometrial Cancer / California Primary Care Opportunities (FREE)
By the Editors Here's what we chose for you from NEJM Group today:NEJM Clinical Practice Center: Perspective: There is sexism in medicine, but there may also be a more insidious obstacle. … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 19, 2017 Category: Primary Care Source Type: news

Your NEJM Group Today: Protecting Physician Speech / Changing Face of Endocarditis / Colorado Hospitalist Opportunity (FREE)
By the Editors Here are our top picks from NEJM Group:NEJM Audio Interview: Protecting Physician Speech: Professor Wendy … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 18, 2017 Category: Primary Care Source Type: news

Nearly 1 in 5 Older Gastric Band Patients Require Reoperation (FREE)
By Amy Orciari Herman Edited by Susan Sadoughi, MD, and Richard Saitz, MD, MPH, FACP, DFASAM Nearly one in five Medicare beneficiaries who undergo laparoscopic gastric banding end up needing an additional band-related surgery, according to a … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 18, 2017 Category: Primary Care Source Type: news

Experimental Cholesterol Drug Does Not Cut Risk for Cardiovascular Events (FREE)
By the Editors Evacetrapib, an experimental cholesterol ester transfer protein inhibitor, raises HDL cholesterol and lowers … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 18, 2017 Category: Primary Care Source Type: news

Agencies Warn of Faulty Blood Tests for Lead, Recommend Retesting (FREE)
By Kelly Young Edited by Susan Sadoughi, MD, and Richard Saitz, MD, MPH, FACP, DFASAM Some blood tests made by Magellan Diagnostics may falsely report low lead levels in children and … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 18, 2017 Category: Primary Care Source Type: news

USPSTF Maintains Stance Against Using Hormone Therapy to Prevent Chronic Conditions (FREE)
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM The U.S. Preventive Services Task Force, in a draft recommendation statement, is again advising against the use … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 17, 2017 Category: Primary Care Source Type: news

FDA Adds Boxed Warning to Canagliflozin for Increased Amputation Risk (FREE)
By Kristin J. Kelley Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM The FDA is adding new warnings — including a boxed warning — to labels for … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 17, 2017 Category: Primary Care Source Type: news

Medi-scam at Medicare Advantage? Insurers Accused of Gaming the System (FREE)
By Joe Elia Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM UnitedHealth Group and other insurance companies stand accused of " systematically bilking " Medicare Advantage of billions of dollars … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 17, 2017 Category: Primary Care Source Type: news

Your NEJM Group Today: Improving Patient Engagement / Better Adenoma Detection = Cancer Prevention / Virginia Dermatology Opportunity (FREE)
By the Editors Here's what we chose for you from NEJM Group today:NEJM Catalyst: Insights Report: … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 17, 2017 Category: Primary Care Source Type: news

Intra-Articular Corticosteroids Show No Benefit in Knee Osteoarthritis (FREE)
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM Intra-articular triamcinolone does not help relieve knee pain in adults with osteoarthritis — and might even lead … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 17, 2017 Category: Primary Care Source Type: news

Study Seems to Support Targeted Lipid Screening in Younger Adults (FREE)
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD New findings in the Annals of Internal Medicine seem to support a targeted approach to lipid screening in younger adults. Currently, the American College of Cardiology/American Heart Association recommend … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 15, 2017 Category: Primary Care Source Type: news

Shorter Window from Menarche to Menopause Tied to Heart Failure Risk (FREE)
By the Editors In postmenopausal women, shorter reproductive duration — that is, the time from … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 15, 2017 Category: Primary Care Source Type: news

Many Americans Skipping MMR Vaccination Before Traveling Abroad (FREE)
By Kelly Young Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD Of U.S. adults who go to travel clinics before traveling internationally, only about half of those eligible for the measles, mumps, and rubella (MMR) … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 15, 2017 Category: Primary Care Source Type: news

Your NEJM Group Today: Tympanic-Membrane Perforations After Blast Injury / Depression & Dementia / Kentucky Electrophysiology Opportunity (FREE)
By the Editors Take a look at today's offering from NEJM Group:NEJM Clinical Practice Center: Image in Clinical Medicine: A 30-year-old man was … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 15, 2017 Category: Primary Care Source Type: news

Interview: Fecal Transplants and the Gut Microbiome (FREE)
By the Editors Clinical Conversations interviews Dr. Zain Kassam, chief medical officer at … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 15, 2017 Category: Primary Care Source Type: news

Rising Maternal Mortality Rate in the U.S. Examined (FREE)
By Amy Orciari Herman Edited by Susan Sadoughi, MD, and Andr é Sofair, MD, MPH The maternal mortality rate is rising in the United States — but is declining in other developed countries — according to a ProPublica and NPR story. Every year in the … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 15, 2017 Category: Primary Care Source Type: news

From the Blogs: Poll: Most Important EMR Feature? / Leaving Against Medical Advice (FREE)
By the Editors Take a look at what the NEJM Journal Watch bloggers are talking about … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 15, 2017 Category: Primary Care Source Type: news

Breast Implant-Associated Lymphoma Highlighted in New York Times (FREE)
By Amy Orciari Herman Edited by Susan Sadoughi, MD, and Andr é Sofair, MD, MPH Patients may ask about a New York Times story highlighting the small but real risk for anaplastic large-cell lymphoma in women with breast … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 15, 2017 Category: Primary Care Source Type: news

WHO Confirms Ebola Outbreak in Congo (FREE)
By the Editors The World Health Organization has confirmed two cases of Ebola in the Democratic Republic of … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 15, 2017 Category: Primary Care Source Type: news