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Total 131 results found since Jan 2013.

The Effect of Coffee and Quantity of Consumption on Specific Cardiovascular and All-Cause Mortality: Coffee Consumption Does Not Affect Mortality
This study aimed to delineate this association using population representative data from the National Health and Nutrition Examination Survey III. Patients were included in the study if all the following criteria were met: (1) follow-up mortality data were available, (2) age of at least 45 years, and (3) reported amount of average coffee consumption. A total of 8608 patients were included, with patients stratified into the following groups of average daily coffee consumption: (1) no coffee consumption, (2) less than 1 cup, (3) 1 cup a day, (4) 2–3 cups, (5) 4–5 cups, (6) more than 6 cups a day. Odds ratios, 95% confide...
Source: American Journal of Therapeutics - January 1, 2016 Category: Drugs & Pharmacology Tags: Therapeutic Reviews Source Type: research

Effects of coffee/caffeine on brain health and disease: What should I tell my patients?
Abstract Over the last decade, Food Regulation Authorities have concluded that coffee/caffeine consumption is not harmful if consumed at levels of 200 mg in one sitting (around 2½ cups of coffee) or 400 mg daily (around 5 cups of coffee). In addition, caffeine has many positive actions on the brain. It can increase alertness and well-being, help concentration, improve mood and limit depression. Caffeine may disturb sleep, but only in sensitive individuals. It may raise anxiety in a small subset of particularly sensitive people. Caffeine does not seem to lead to dependence, although a minority of people experi...
Source: Practical Neurology - December 16, 2015 Category: Neurology Authors: Nehlig A Tags: Pract Neurol Source Type: research

Shortcut to Better Brain Power
Natural caffeine is one of the oldest stimulants in the world. And it’s loaded with health benefits. It can enhance your mental clarity and focus, and it’s a potent antioxidant… as long as you take it in moderation and it comes from natural sources. But the problem with most energy drinks these days is the caffeine itself. It’s unnatural and synthetic. We’ve known for a long time that the antioxidant power of caffeine cuts the risk of dying from heart disease or developing Alzheimer’s. But now a study from the Department of Nutrition at the Harvard School of Public Health, researchers looked at 30 years of data...
Source: Al Sears, MD Natural Remedies - December 15, 2015 Category: Complementary Medicine Authors: Al Sears Tags: Brain Health caffeine coffee guarana Source Type: news

9 Healthy Reasons To Indulge Your Coffee Cravings
There's no need to feel guilty about your morning cup o’ joe. On the contrary: People who drink four or more cups of coffee a day have up to a 20 percent lower risk of melanoma than those who sip the dark stuff less often, according to a 2015 study in the Journal of the National Cancer Institute. But this study is hardly the first one touting good news for java junkies. "Coffee is incredibly rich in antioxidants, which are responsible for many of its health benefits," says Joy Bauer, RD, nutrition and health expert for Everyday Health and The Today Show. And studies show that its caffeine content may also play a prot...
Source: Healthy Living - The Huffington Post - September 20, 2015 Category: Consumer Health News Source Type: news

Chlorogenic acid, a polyphenol in coffee, protects neurons against glutamate neurotoxicity
Publication date: 15 October 2015 Source:Life Sciences, Volume 139 Author(s): Yoshinori Mikami, Toshiko Yamazawa Aims The present study has been designed to explore the molecular mechanism of chlorogenic acid (CGA) in the protective effect against glutamate-induced neuronal cell death. Main methods Cortical neurons in primary culture were exposed to 300μM l-glutamic acid or vehicle, with or without 10μM CGA or 10μM MK-801. After 16h, primary cultures were stained with propidium iodide (PI)/Hoechst or calcein. Double-staining with PI and Hoechst was performed to confirm whether cell death induced by glutamate was ap...
Source: Life Sciences - August 28, 2015 Category: Biology Source Type: research

Inverse Relationship between Coffee Consumption and Cerebral Microbleeds in Men, but Not Women
Studies evaluating the association between coffee consumption and neurovascular diseases have frequently yielded contradictory results. The aim of this study was to investigate the association of coffee consumption with small-vessel disease (SVD) incidence in a healthy urban population while accounting for multiple demographic and lifestyle risk factors.
Source: Journal of Stroke and Cerebrovascular Diseases - August 6, 2015 Category: Neurology Authors: Masaki Shinoda, Motoharu Fujii, Osamu Takahashi, Akiko Kawatsu, Akihiro Uemura, Yasunari Niimi Source Type: research

AHA: Drinking Coffee May Cut Risk of Heart Failure, Stroke
Each additional cup consumed per week tied to a decrease in risk compared with no coffee intake
Source: Pulmonary Medicine News - Doctors Lounge - November 11, 2014 Category: Respiratory Medicine Tags: Cardiology, Endocrinology, Family Medicine, Geriatrics, Gynecology, Internal Medicine, Nephrology, Neurology, Nursing, Pulmonology, Conference News, Source Type: news

Coffee: A Selected Overview of Beneficial or Harmful Effects on the Cardiovascular System?
Abstract With a history that began in 800 A.D., coffee is the most popular drink known and as a result, the issues regarding its physiologic effects deserve attention. Maintaining alertness is a well-known benefit and in addition, the cardiovascular (CV) effects of the active compounds, which include polyphenols and caffeine, must be considered. Genetics are relevant and where slow caffeine metabolism is inherent, the risk of nonfatal myocardial (MI) has been shown to be increased. Overall risk for coronary heart disease (CHD) is not supported and unless there is excessive intake, congestive heart failure (CHF) is...
Source: Current Vascular Pharmacology - October 2, 2014 Category: Drugs & Pharmacology Authors: Whayne Jr TF Tags: Curr Vasc Pharmacol Source Type: research

Effects of Habitual Coffee Consumption on Cardiometabolic Disease, Cardiovascular Health, and All-cause Mortality: O'Keefe JH, Bhatti SK, Patil HR. J Am Coll Cardiol 2013;62:1043−51.
This study examines existing data regarding coffee consumption and its effect on health and all-cause mortality. Coffee consumption confers a benefit in the reduction of Type II diabetes mellitus (T2DM). There was significant reduction in a dose-dependent relationship of coffee consumption and reduction of T2DM. Caffeinated and noncaffeinated beverages confer the same benefit. The authors conclude that coffee's effect on serum lipids is a dose-dependent increase in serum total cholesterol and a nonsignificant increase in low-density lipoprotein concentrations in only boiled preparations of coffee, but not for filtered coff...
Source: The Journal of Emergency Medicine - April 24, 2014 Category: Emergency Medicine Authors: Java Tunson Tags: Abstracts Source Type: research

Coffee: A Panacea or Snake Oil for the Liver?
The United States is the world's biggest consumer of coffee. Approximately 83% of adults drink coffee in the United States according to the National Coffee Association's 2013 survey. There has been much interest in the potential health benefits both in scientific journals and lay media. One such example is a study by Freedman et al,1 which showed a significant, dose-dependent, inverse relationship between coffee and mortality. The benefits spanned a broad range of health conditions: consumption of coffee was associated with reduced mortality not only from heart disease, stroke, and diabetes, but also infections, respirato...
Source: Clinical Gastroenterology and Hepatology - April 24, 2014 Category: Gastroenterology Authors: Radhika Kumari, W. Ray Kim Tags: Original article Source Type: research

Reply Effects of Habitual Coffee Consumption on Vascular Function
We thank Dr. Siasos and colleagues for pointing out that habitual coffee consumption has been associated with improved endothelial function in elderly inhabitants of Ikaria Island (1). The improvement in endothelial function may in part account for the associations of moderate coffee intake (about 2 to 4 cups daily) with lower risks for coronary heart disease and stroke (2). Indeed, even in the setting of endothelium damage, coffee has the ability to prevent arterial thrombus formation, a benefit that is independent of its caffeine content (3). Recent studies also indicate that moderate daily coffee intake may confer pro...
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - February 10, 2014 Category: Cardiology Source Type: research

Long-Term Coffee Consumption and Risk of Cardiovascular Disease: A Systematic Review and a Dose-Response Meta-Analysis of Prospective Cohort Studies.
CONCLUSIONS: A non-linear association between coffee consumption with CVD risk was observed in this meta-analysis. Moderate coffee consumption was inversely significantly associated with CVD risk, with the lowest CVD risk at 3 to 5 cups/d, and heavy coffee consumption was not associated with elevated CVD risk. PMID: 24201300 [PubMed - as supplied by publisher]
Source: Circulation - November 7, 2013 Category: Cardiology Authors: Ding M, Bhupathiraju SN, Satija A, van Dam RM, Hu FB Tags: Circulation Source Type: research

Reply: Effects of Habitual Coffee Consumption on Vascular Function
We thank Dr. Siasos and colleagues for pointing out that habitual coffee consumption has been associated with improved endothelial function in elderly inhabitants of Ikaria Island . The improvement in endothelial function may in part account for the associations of moderate coffee intake (about 2 to 4 cups daily) with lower risks for coronary heart disease and stroke . Indeed, even in the setting of endothelium damage, coffee has the ability to prevent arterial thrombus formation, a benefit that is independent of its caffeine content . Recent studies also indicate that moderate daily coffee intake may confer protection a...
Source: Journal of the American College of Cardiology - November 1, 2013 Category: Cardiology Authors: James J. DiNicolantonio, James H. O'Keefe, Carl J. Lavie Tags: Letters to the Editor Source Type: research

Coffee and tea: perks for health and longevity?
Abstract PURPOSE OF REVIEW: Tea and coffee, after water, are the most commonly consumed beverages in the world and are the top sources of caffeine and antioxidant polyphenols in the American diet. The purpose of this review is to assess the health effects of chronic tea and/or coffee consumption. RECENT FINDINGS: Tea consumption, especially green tea, is associated with significantly reduced risks for stroke, diabetes and depression, and improved levels of glucose, cholesterol, abdominal obesity and blood pressure. Habitual coffee consumption in large epidemiological studies is associated with reduced mortali...
Source: Diabetes Metab - September 25, 2013 Category: Endocrinology Authors: Bhatti SK, O'Keefe JH, Lavie CJ Tags: Curr Opin Clin Nutr Metab Care Source Type: research

Effects of Habitual Coffee Consumption on Cardiometabolic Disease, Cardiovascular Health, and All-Cause Mortality
Coffee, after water, is the most widely consumed beverage in the United States, and is the principal source of caffeine intake among adults. The biological effects of coffee may be substantial and are not limited to the actions of caffeine. Coffee is a complex beverage containing hundreds of biologically active compounds, and the health effects of chronic coffee intake are wide ranging. From a cardiovascular (CV) standpoint, coffee consumption may reduce the risk of type 2 diabetes mellitus and hypertension, as well as other conditions associated with CV risk such as obesity and depression; but it may adversely affect lipi...
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - September 9, 2013 Category: Cardiology Source Type: research