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Nutrition: Vitamin D

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Total 344 results found since Jan 2013.

Anesthetic considerations in hyperparathyroid crisis: A case report
Introduction: Hyperparathyroid crisis is a rare and potentially life-threatening complication of severe calcium intoxication. Parathyroidectomy is the only curative method for hyperparathyroid crisis. Several case reports and case series have been published on the medical and surgical treatments for hyperparathyroid crisis, however, few reports have focused on the associated perioperative anesthetic management. Patient concerns: A 48-year-old Chinese woman presented with a 2-week history of nausea and vomiting and complained of mental status alteration including confusion and agitation in the 24 hours prior to...
Source: Medicine - January 8, 2021 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Association of Fibroblast Growth Factor 23 With Ischemic Stroke and Its Subtypes: A Mendelian Randomization Study
In this study, we aimed to assess the association of FGF23 with ischemic stroke and its subtypes by applying a Mendelian randomization (MR) framework. Five genetic variants obtained from a genome-wide association study involving 16,624 European subjects were used as valid instruments of circulating FGF23 levels. MR was applied to infer the causality of FGF23 levels and the risk of ischemic stroke using data from the MEGASTROKE consortium. Subsequently, several MR analyses, including inverse-variance weighted meta-analysis, MR-Egger, weighted median estimate (WME), MR Pleiotropy Residual Sum and Outlier were performed. The ...
Source: Frontiers in Genetics - December 23, 2020 Category: Genetics & Stem Cells Source Type: research

Study: Fish Oil Doesn ’ t Seem To Prevent Heart Problems
This study is consistent with earlier trials. The US Food and Drug Administration approved the fish oil-based drug Vascepa for heart attack and stroke prevention in 2019. Nissen hopes the FDA will take a look at these studies and reconsider that decision. “But it’s hard to get something undone once the genie gets out of the bottle,” he said. An editorial in the journal that accompanies the study written by Dr. Gregory Curfman, assistant professor of medicine at Harvard Medical School, also suggested the FDA should require a postmarketing clinical trial of a high-dose of fish oil, such as Vascepa, vs. corn...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - November 16, 2020 Category: Consumer Health News Authors: CBS Boston Tags: Boston News Health Syndicated CBSN Boston CNN fish oil Source Type: news

The severity of vasomotor symptoms and number of menopausal symptoms in postmenopausal women and select clinical health outcomes in the Women's Health Initiative Calcium and Vitamin D randomized clinical trial
This study evaluated whether vasomotor symptom (VMS) severity and number of moderate/severe menopausal symptoms (nMS) were associated with health outcomes, and whether calcium and vitamin D (CaD) modified the risks. Methods: The Women's Health Initiative CaD study was a double blind, randomized, placebo-controlled trial, which tested 400 IU of 25-hydroxyvitamin-D and 1,000 mg of calcium per day in women aged 50 to 79 years. This study included 20,050 women (median follow-up of 7 y). The outcomes included hip fracture, colorectal cancer, invasive breast cancer, all-cause mortality, coronary heart disease, stroke, cardi...
Source: Menopause - October 30, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Investigation of the Relationship Between Breath Retention Time and Blood Parameters in Stroke Patients
Conclusion: Partial oxygen and carbon dioxide pressures and blood elements in the blood affect the breath holding time. People with high blood storage capacity and carbon dioxide and oxygen capacity can hold their breath longer. As a result, we think that the higher the hemoglobin and hematocrit levels in the blood, the longer the breath holding time can increase.
Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: Yildiz, A., Mustafaoglu, R., Dincer, S. Tags: Clinical respiratory physiology, exercise and functional imaging Source Type: research

Low vitamin D levels affect left ventricular wall thickness in severe aortic stenosis
Conclusion Among patients with severe degenerative aortic stenosis, vitamin D deficiency is common. We found a significant association between left ventricular wall thickness and vitamin D levels, suggesting a potential role of this hormone in modulating hypertrophic remodelling in these patients. However, future larger studies are certainly needed to confirm our findings and to define their prognostic implications.
Source: Journal of Cardiovascular Medicine - October 6, 2020 Category: Cardiology Tags: Research articles: Valvular heart disease Source Type: research

Causal inference and evidence-based recommendations in occupational health and safety research
In this issue of the Journal, a group of distinguished Nordic researchers, led by Anne Helene Garde and including four of our Associated Editors, present a discussion paper that originated from a workshop and provides detailed recommendations on night shift work (1). The recommendations are very clear: to protect workers ’ health, night shift schedules should have: (i) ≤3 consecutive night shifts; (ii) shift intervals of ≥11 hours; and (iii) ≤9 hours shift duration. For pregnant women, night work should be limited to one shift per week. The authors acknowledge that under circumstances allowing better possibi lities...
Source: Scandinavian Journal of Work, Environment and Health - October 2, 2020 Category: Occupational Health Tags: Editorial Source Type: research

Post-ischemic stroke systemic inflammation: Immunomodulation by progesterone and vitamin D hormone.
In this study, we examined the immunomodulatory effects of progesterone (P4) alone and in combination with vitamin D hormone (VDH) on acute phase post-stroke peripheral immune dysfunction and functional/behavioral deficits. Adult rats underwent transient middle cerebral artery occlusion/reperfusion (tMCAO) and delayed systemic inflammation was induced by injections of lipopolysaccharide (LPS) beginning 24 h post-stroke. Animals were tested for behavioral outcomes and immune function at day 4 post-stroke. We also measured infarction volume and markers of neuronal inflammation (GFAP, IL-6) and apoptosis (cleaved caspase-3) ...
Source: Neuropharmacology - September 16, 2020 Category: Drugs & Pharmacology Authors: Atif F, Yousuf S, Espinosa-Garcia C, Harris WAC, Stein DG Tags: Neuropharmacology Source Type: research

Vitamin D3/vitamin D receptor signaling mitigates symptoms of post-stroke depression in mice by upregulating hippocampal BDNF expression
Publication date: Available online 1 September 2020Source: Neuroscience ResearchAuthor(s): Yunxuan Xu, Lingyun Liang
Source: Neuroscience Research - September 3, 2020 Category: Neuroscience Source Type: research

Risk Factors for the Recurrence of Benign Paroxysmal Positional Vertigo: A Systematic Review and Meta-Analysis.
CONCLUSION: These findings strengthen clinical awareness of early warning to identify patients with potential relapse risk of BPPV and clinicians should counsel patients regarding the importance of follow-up after diagnosis of BPPV. PMID: 32776833 [PubMed - as supplied by publisher]
Source: Ear, Nose and Throat Journal - August 9, 2020 Category: ENT & OMF Authors: Li S, Wang Z, Liu Y, Cao J, Zheng H, Jing Y, Han L, Ma X, Xia R, Yu L Tags: Ear Nose Throat J Source Type: research

Autophagy in diabetic nephropathy: a review
AbstractDiabetes mellitus (DM) is the leading cause of end stage renal disease. 40% of the patients worldwide will require replacement therapy after 20  years of DM worldwide. Early-stage diabetic nephropathy is characterized by hyperfiltration related to hypeglycemia-induced afferent artery vasodilatation with micro-and macroalbuminuria. Later on, proteinuria with arterial hypertension may appear, culminating in glomerular filtration rate (GFR) d ecline and end stage renal disease. Forty percent of diabetic patients develop microvascular and macrovascular complications, with increased risk among patients with genetic pre...
Source: International Urology and Nephrology - July 12, 2020 Category: Urology & Nephrology Source Type: research

Telling friend from foe in emergency vertigo and dizziness: does season and daytime of presentation help in the differential diagnosis?
The objective of the present study was to analyze frequency and distribution patterns of specific vestibular and non-vestibular diagnoses in an interdisciplinary university emergency room (ER), including data on daytime and season of presentation. A retrospective chart analysis of all patients seen in a one-year period was performed. In the ER 4.23% of all patients presented with VD (818 out of 19,345). The most frequent-specific diagnoses were BPPV (19.9%), stroke/transient ischemic attack (12.5%), acute unilateral vestibulopathy/vestibular neuritis (UVH; 8.3%), and functional VD (8.3%). Irrespective of the diagnosis, the...
Source: Journal of Neurology - July 10, 2020 Category: Neurology Source Type: research

Risk Factors for the Occurrence of Benign Paroxysmal Positional Vertigo: A Systematic Review and Meta-Analysis
Conclusion: Female gender, vitamin D deficiency, osteoporosis, migraine, head trauma, and high TC level were risk factors for the occurrence of BPPV. However, the effects of other risk factors on BPPV occurrence need further investigations.
Source: Frontiers in Neurology - June 22, 2020 Category: Neurology Source Type: research

Vitamin D and Stroke: Effects on Incidence, Severity, and Outcome and the Potential Benefits of Supplementation
Vitamin D serum level has been positively associated with improved cardiovascular health, especially with reduction of stroke risk. This systemic review summarizes and synthesizes findings from studies relevant to the relationship between vitamin D and stroke risk, severity, and outcome; potential mechanisms explaining such a relationship; and outcomes from vitamin D supplementation. The literature shows that vitamin D deficiency is a significant risk factor for ischemic stroke, with sun exposure, sex, age, race, diabetes, and genetics playing a role as well. Stroke severity and short- and long-term outcomes also worsen wi...
Source: Frontiers in Neurology - June 9, 2020 Category: Neurology Source Type: research

Vitamin D supplementation, cardiac events and stroke: A systematic review and meta-regression analysis
Publication date: June 2020Source: IJC Heart & Vasculature, Volume 28Author(s): Matthew Nudy, George Krakowski, Mehrdad Ghahramani, Mohammed Ruzieh, Andrew J. Foy
Source: IJC Heart and Vasculature - May 21, 2020 Category: Cardiology Source Type: research