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Total 109 results found since Jan 2013.

Distensibility index of the inferior vena cava in experimental acute respiratory distress syndrome
In conclusion, a dIVC threshold<25% was associated with positive response after volume expansion and could be used to titrate fluids in endotoxin-induced ARDS.
Source: Respiratory Physiology and Neurobiology - December 22, 2016 Category: Respiratory Medicine Source Type: research

Bagged salads 'pose salmonella risk,' say researchers
Conclusion This laboratory study principally demonstrates that salad leaf juice – released from salad leaves when they are damaged or broken – supports the growth of salmonella bacteria, even at fridge temperature. If leaves are contaminated with salmonella, this isn't removed by washing in water. The results don't show that all packaged salad leaves are contaminated with gut bacteria like salmonella. What they do show is that if the bags have been contaminated with gut bacteria, these bacteria will replicate, even in the fridge, and there's little you can do to remove them. The best thing to do is to throw the bag o...
Source: NHS News Feed - November 21, 2016 Category: Consumer Health News Tags: Food/diet Source Type: news

The model homologue of the partially defective human 5,10-methylenetetrahydrofolate reductase, considered as a risk factor for stroke due to increased homocysteine level, can be protected and reactivated by heat shock proteins
AbstractThe A222  V substitution in the humanMTHFR gene product (5,10-methylenetetrahydrofolate reductase) is responsible for a decreased activity of this enzyme. This may cause an increased homocysteine level, considered as a risk factor for arteriosclerosis and stroke. The bacterial homologue of the human enzyme, MetF, has been found to be a useful model in genetic and biochemical studies. The similarity ofEscherichia coli MetF and human MTHFR proteins is so high that particular mutations in the corresponding human gene can be reflected by the bacterial mutants. For example, the A222  V substitution in MTHFR (caused by...
Source: Metabolic Brain Disease - September 22, 2016 Category: Neurology Source Type: research

In the Raw: To Cook or Not to Cook?
Imagine never again savoring the smell of baking cakes or charbroiled steak. Could you? Why would you? Yet some people worldwide are turning away not only from meat and processed food, but also from cooking. Welcome to the raw food diet. As the Standard American Diet becomes more fat-laden, sugar-sated, and processed, the prevalence of metabolic disorders, obesity, type 2 diabetes, and cardiovascular disease (CVD) are soaring. According to the Centers for Disease Control and Prevention (CDC), obesity now affects nearly 35 percent of the population of the United States, over 29 million people have been diagnosed with t...
Source: Healthy Living - The Huffington Post - August 4, 2016 Category: Consumer Health News Source Type: news

Engineering, expression and purification of a chimeric fibrin-specific streptokinase
Publication date: Available online 3 August 2016 Source:Protein Expression and Purification Author(s): Mohammad Naser Taheri, Abbas Behzad-Behbahani, Gholamreza Rafiei Dehbidi, Saeede Salehi, Sedigheh Sharifzadeh Streptokinase is a valuable fibrinolytic agent used to cope with myocardial infarction and brain stroke. Despite its high efficiency in dissolving blood clots, streptokinase (SK) has no specificity in binding fibrin, causing some problems such as internal bleedings following its administration. To make streptokinase fibrin specific and limit the fibrinolytic process to the clot location, we engineered a chimeric ...
Source: Protein Expression and Purification - August 2, 2016 Category: Biochemistry Source Type: research

Evaluation of laser bacterial anti ‐fouling of transparent nanocrystalline yttria‐stabilized‐zirconia cranial implant
ConclusionsOur results show that E. coli biofilm formation across the thickness of the nc‐YSZ implant can be disrupted using NIR laser treatment. The results of this in vitro study suggest that using nc‐YSZ as a cranial implant in vivo may also allow for locally selective, non‐invasive, chronic treatment of bacterial layers (fouling) that might form under cranial implants, without causing adverse thermal damage to the underlying host tissue when appropriate laser parameters are used. Lasers Surg. Med. © 2016 Wiley Periodicals, Inc.
Source: Lasers in Surgery and Medicine - July 7, 2016 Category: Laser Surgery Authors: Yasaman Damestani, Natalie De Howitt, David L. Halaney, Javier E. Garay, Guillermo Aguilar Tags: Basic Science Source Type: research

Evaluation of laser bacterial anti‐fouling of transparent nanocrystalline yttria‐stabilized‐zirconia cranial implant
ConclusionsOur results show that E. coli biofilm formation across the thickness of the nc‐YSZ implant can be disrupted using NIR laser treatment. The results of this in vitro study suggest that using nc‐YSZ as a cranial implant in vivo may also allow for locally selective, non‐invasive, chronic treatment of bacterial layers (fouling) that might form under cranial implants, without causing adverse thermal damage to the underlying host tissue when appropriate laser parameters are used. Lasers Surg. Med. © 2016 Wiley Periodicals, Inc.
Source: Lasers in Surgery and Medicine - June 30, 2016 Category: Laser Surgery Authors: Yasaman Damestani, Natalie De Howitt, David L. Halaney, Javier E. Garay, Guillermo Aguilar Tags: Basic Science Source Type: research

Native Valve Emphysematous Endocarditis Caused by Finegoldia magna in a Novel Pathogenic Role
We describe a case of native valve emphysematous endocarditis presenting with stroke and ultimately leading to left ventricular rupture and the patient's untimely death. Premortem blood cultures and postmortem pathologic and histologic examination yielded Finegoldia magna (formerly Peptostreptococcus magnus) in a novel pathogenic role. As detection methods continue to improve for Finegoldia magna, it is important to increase awareness of the pathogenic role of this organism.
Source: Infectious Diseases in Clinical Practice - December 28, 2015 Category: Infectious Diseases Tags: Case Reports Source Type: research

Cloning, Prokaryotic Expression and Functional Analysis of Squalene Synthase (SQS) in Magnolia officinalis
In this study, a full-length cDNA of squalene synthase was cloned from M. officinalis and designated MoSQS (GenBank accession no.KT223496). The gene contains a 1240-bp open reading frame and it encodes a protein with 409 amino acids. Bioinformatic and phylogenetic analysis clearly suggested that MoSQS shared high similarity with squalene synthases among other plants. Prokaryotic expression showed that a transmembrane domain-deleted (385–409 aa) MoSQS mutant (MoSQSΔTM) could be expressed in its soluble form in Escherichia coli Transetta (DE3). GC-MS analysis showed that squalene was detected in an in vitro reaction mixtu...
Source: Protein Expression and Purification - December 13, 2015 Category: Biochemistry Source Type: research

Do Physically Active Patients Have Better Functional Outcome after Stroke? A Systematic Review
Stroke is one of the major causes of mortality and, among survivors, disability. Physical activity has a protective effect maybe due to a major control of risk factors, such as hypertension, diabetes mellitus, and body weight. However, the effect of prestroke physical activity and the poststroke functional outcomes needs clarification.
Source: Journal of Stroke and Cerebrovascular Diseases - December 3, 2015 Category: Neurology Authors: Mariely Trigo Tumasz, Tathiana Trócoli, Matheus Fernandes de Oliveira, Ricardo Rezende Campos, Ricardo Vieira Botelho Source Type: research

10 Scary Ways Your Office Job Is Killing You
This article originally appeared on YourTango. More from YourTango: Why I'm Giving Up My Cushy Job To Travel The World In An RV 7 Ways To Keep Their Passive-Aggression From Driving You Nuts 10 Uplifting Quotes That Will Get You Through The Day 5 Things You MUST Try Before Turning To Mood-Boosting Medicines Quotes To Share With Your Long-Distance Lover Also on HuffPost: -- This feed and its contents are the property of The Huffington Post, and use is subject to our terms. It may be used for personal consumption, but may not be distributed on a website.
Source: Healthy Living - The Huffington Post - October 28, 2015 Category: Consumer Health News Source Type: news

Rosiglitazone Promotes White Matter Integrity and Long-Term Functional Recovery After Focal Cerebral Ischemia Basic Sciences
Conclusions— Rosiglitazone treatment improves long-term white matter integrity after cerebral ischemia, at least, in part, by promoting oligodendrogenesis and facilitating microglial polarization toward the beneficial M2 phenotype.
Source: Stroke - August 24, 2015 Category: Neurology Authors: Han, L., Cai, W., Mao, L., Liu, J., Li, P., Leak, R. K., Xu, Y., Hu, X., Chen, J. Tags: Other Stroke Treatment - Medical Basic Sciences Source Type: research

Super Nutrient’s Liver Surprise
I was one of the first doctors to talk about the incredible benefits of the super-nutrient pyrroloquinoline quinone, or PQQ for short. I was also one of the first doctors to recommend it to patients. Now I recommend this essential nutrient and powerful antioxidant to almost everyone who comes to see me at my wellness clinic. Researchers have only just recently begun to understand the many important roles of PQQ on the body’s cellular processes. Not only does it possess extraordinary energy-giving qualities and have the power to ease nerve pain and battle Alzheimer’s, it has the potential to become the world’s stronge...
Source: Al Sears, MD Natural Remedies - June 10, 2015 Category: Complementary Medicine Authors: Dr. Al Sears Tags: Anti-Aging Cancer CoQ10 Source Type: news

Disproportionate effects of dementia on hospital discharge disposition in common hospitalization categories
CONCLUSIONSDementia proportions in many hospitalization categories have increased. The variable effect of dementia on home discharge suggests that dementia has a differential influence on hospital discharge disposition depending on the DRG. These findings have implications for healthcare allocation and long‐term care planning. Journal of Hospital Medicine 2015. © 2015 Society of Hospital Medicine
Source: Journal of Hospital Medicine - June 7, 2015 Category: Hospital Management Authors: Robert Y. Lin, Brian C. Scanlan, William Liao, Truc Phuong Thanh Nguyen Tags: Original Research Source Type: research

Effects of early hemodynamic resuscitation on left ventricular performance and microcirculatory function during endotoxic shock
Background: Microcirculation and macrohemodynamics are severely compromised during septic shock. However, the relationship between these two compartments needs to be further investigated. We hypothesized that early resuscitation restores left ventricular (LV) performance and microcirculatory function but fails to prevent metabolic disorders. We studied the effects of an early resuscitation protocol (ERP) on LV pressure/volume loops-derived parameters, sublingual microcirculation, and metabolic alterations during endotoxic shock. Methods: Twenty-five pigs were randomized into three groups: LPS group: Escherichia coli lipopo...
Source: Intensive Care Medicine Experimental - May 8, 2015 Category: Surgery Authors: Alejandra LópezJuan GrignolaMartín AnguloIgnacio AlvezNicolás NinGonzalo LacuestaManuel BazPablo CardinalIvana PrestesJuan BouchacourtJuan RivaCan InceFrancisco Hurtado Source Type: research