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News & Announcements
(Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - January 17, 2018 Category: Laser Surgery Tags: News & Announcements Source Type: research

Issue Information
(Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - January 17, 2018 Category: Laser Surgery Tags: Issue Information Source Type: research

Noninvasive optical spectroscopy for identification of non ‐melanoma skin cancer: Pilot study
ConclusionThis pilot trial utilizes optical spectroscopy as a noninvasive method for determining cutaneous lesion histology. Effect sizes observed across optical parameters for benign and malignant tissue types will guide larger prospective studies that may ultimately lead to prediction of lesional histology without need for invasive biopsy. Lasers Surg. Med. © 2018 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - January 13, 2018 Category: Laser Surgery Authors: David J. Carpenter, Mirabelle B. Sajisevi, Nikita Chapurin, Clifford Scott Brown, Tracy Cheng, Gregory M. Palmer, Daniel S. Stevenson, Caroline L. Rao, Russell P. Hall, Charles R. Woodard Tags: Preclinical Reports Source Type: research

A split ‐body study evaluating the efficacy of a conformable surface cryolipolysis applicator for the treatment of male pseudogynecomastia
ConclusionA conformable surface cryolipolysis applicator was effective in reducing the mean adipose tissue thickness in subjects with male pseudogynecomastia. Lasers Surg. Med. © 2018 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - January 13, 2018 Category: Laser Surgery Authors: Isabela T. Jones, Monique J. Vanaman Wilson, Isabella Guiha, Douglas C. Wu, Mitchel P. Goldman Tags: Clinical Reports Source Type: research

Combination of platelet rich plasma in fractional carbon dioxide laser treatment increased clinical efficacy of for acne scar by enhancement of collagen production and modulation of laser ‐induced inflammation
ConclusionTaken together with human study results combined with the data from cell experiments we suggest that PRP treatment increased fibrogenetic molecules induced by fractional CO2 laser, which have association with clinical effect. Lasers Surg. Med. © 2017 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - December 20, 2017 Category: Laser Surgery Authors: Seonguk Min, Ji Young Yoon, Seon Yong Park, Jungyoon Moon, Hyuck Hoon Kwon, Dae Hun Suh Tags: Clinical Reports Source Type: research

In vitro investigations of propulsion during laser lithotripsy using video tracking
ObjectivesUreteroscopic laser lithotripsy is an important and widely used method for destroying ureter stones. It represents an alternative to ultrasonic and pneumatic lithotripsy techniques. Although these techniques have been thoroughly investigated, the influence of some physical parameters that may be relevant to further improve the treatment results is not fully understood. One crucial topic is the propulsive stone movement induced by the applied laser pulses. To simplify and speed up the optimization of laser parameters in this regard, a video tracking method was developed in connection with a vertical column setup t...
Source: Lasers in Surgery and Medicine - December 20, 2017 Category: Laser Surgery Authors: Maximilian Eisel, Stephan Str öbl, Thomas Pongratz, Frank Strittmatter, Ronald Sroka Tags: Basic Science Source Type: research

News & Announcements
(Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - December 18, 2017 Category: Laser Surgery Tags: News & Announcements Source Type: research

Issue Information
(Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - December 18, 2017 Category: Laser Surgery Tags: Issue Information Source Type: research

Low ‐level ultrahigh‐frequency and ultrashort‐pulse blue laser irradiation enhances osteoblast extracellular calcification by upregulating proliferation and differentiation via transient receptor potential vanilloid 1
ConclusionLLLI with a 405 nm UHF‐USP blue laser enhances extracellular calcification of osteoblasts by upregulating proliferation and differentiation via TRPV1. Lasers Surg. Med. © 2017 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - December 7, 2017 Category: Laser Surgery Authors: Risako Mikami, Koji Mizutani, Akira Aoki, Yukihiko Tamura, Kazuhiro Aoki, Yuichi Izumi Tags: Basic Science Source Type: research

Photofrin ® photodynamic therapy with intratumor photosensitizer injection provides similar tumor response while reducing systemic skin photosensitivity: Pilot murine study
ConclusionsThis pilot study shows that intratumoral administration of Photofrin® has the potential to produce similar tumor outcomes, while reducing systemic skin photosensitivity. Further studies are warranted to characterize and optimize intratumor delivery. Lasers Surg. © 2017 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - December 7, 2017 Category: Laser Surgery Authors: Timothy M. Baran Tags: Preclinical Reports Source Type: research

Airborne particulate concentration during laser hair removal: A comparison between cold sapphire with aqueous gel and cryogen skin cooling
BackgroundHigh concentrations of sub‐micron nanoparticles have been shown to be released during laser hair removal (LHR) procedures. These emissions pose a potential biohazard to healthcare workers that have prolonged exposure to LHR plume. ObjectiveWe sought to demonstrate that cold sapphire skin cooling done in contact mode might suppress plume dispersion during LHR. MethodsA total of 11 patients were recruited for laser hair removal. They were treated on the legs and axilla with a 755 or 1064 nm millisecond‐domain laser equipped with either (i) cryogen spray (CSC); (ii) refrigerated air (RA); or (iii) contact...
Source: Lasers in Surgery and Medicine - December 7, 2017 Category: Laser Surgery Authors: Edward V. Ross, Gary S. Chuang, Arisa E. Ortiz, Scott A. Davenport Tags: Clinical Reports Source Type: research

Quantitative evaluation of collagen and elastic fibers after intense pulsed light treatment of mouse skin
The objective of this study was to quantitatively evaluate the effects of IPL on collagen and elastic fibers in mice. Materials and MethodsForty female BALB/c mice were divided into four subgroups. Group 1 was the control group (n = 10), and groups 2, 3, and 4 were treatment groups (n = 10 in each group). Group 2 received one treatment, group 3 received two treatments, and group 4 received three treatments every 2 weeks. Skin tissue was obtained from irradiated areas 24 hours after the last treatment in each mouse. Collagen fibers were identified using the picrosirius red method. Elastic fibers ...
Source: Lasers in Surgery and Medicine - December 1, 2017 Category: Laser Surgery Authors: Luciana L. Faucz, Sonia E. Will, Consuelo J. Rodrigues, Henrique Hesse, Angelina C. Moraes, Durvanei A. Maria Tags: Preclinical Reports Source Type: research

The synergistic effect of PDT and oxacillin on clinical isolates of Staphylococcus aureus
ConclusionsPDT with porphyrins shows possible new therapeutic options in treating drug‐resistant S. aureus at body sites suitable for irradiation. The synergistic effect of DP‐PDT with oxacillin on clinical strains illustrates the potential of PDT to augment traditional antibiotic treatment based on cell wall inhibitors. Lasers Surg. Med. 9999:1–17, 2018. © 2018 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - December 1, 2017 Category: Laser Surgery Authors: Natanel Iluz, Yasmin Maor, Natan Keller, Zvi Malik Tags: Basic Science Source Type: research

Effect of low ‐level laser therapy on the healing of sites grafted with coagulum, deproteinized bovine bone, and biphasic ceramic made of hydroxyapatite and β‐tricalcium phosphate. In vivo study in rats
ConclusionLLLT improved the osteoconductive potential of DBB and HA/βTCP grafts and bone formation in ungrafted areas. Lasers Surg. Med. © 2018 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - December 1, 2017 Category: Laser Surgery Authors: Guilherme J.P.L. de Oliveira, Maur ício A.T. Aroni, Marcell C. Medeiros, Elcio Marcantonio, Rosemary A.C. Marcantonio Tags: Preclinical Reports Source Type: research

Comparative evaluations of hypertrophic scar formation in in vivo models
The objective of the current study was to identify the appropriate method to create the maximal HTS tissue in a reliable manner by comparing three different methods in vivo. Materials and MethodsA 27 ICR mice were tested for the in vivo evaluations. Three different methods were applied to develop wounds on the back of each mice for quantitative evaluations on collagen formation: Group 1 (thermal burn), Group 2 (chemical burn), and Group 3 (physical punch). After injury, each lesion was photographed to examine physical variations in the wound areas. Histological analysis was conducted on days 0, 7, and 28 to assess the exte...
Source: Lasers in Surgery and Medicine - December 1, 2017 Category: Laser Surgery Authors: Myeongjin Kim, Hyejin Kim, Hyun Wook Kang Tags: Preclinical Reports Source Type: research

Effect of laser therapy on quality of life in patients with radiation ‐induced breast telangiectasias
ConclusionBreast cancer patients with RIBT presented with substantial deficits in several HR‐QOL arenas. Laser monotherapy effectively treated the appearance of radiation dermatitis in these patients and also significantly improved HR‐QOL. Lasers Surg. Med. © 2017 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - December 1, 2017 Category: Laser Surgery Authors: Anthony M. Rossi, Nina R. Blank, Kishwer Nehal, Stephen Dusza, Erica H. Lee Tags: Clinical Reports Source Type: research

Comparison of hybrid and cross fragmentation patterns in terms of phaco time and corneal effects
PurposeTo compare two different fragmentation patterns in femtosecond laser‐assisted cataract surgery (FLACS) in terms of phaco values, postoperative endothelial cell count (ECC) and corneal thickness (CT). MethodsThis non‐randomized, retrospective cross‐sectional study included patients with senile cataract of grade 3 who underwent FLACS using the LenSx laser system. In Group 1 (32 eyes), lens fragmentation was created as a cross pattern. In Group 2 (35 eyes), lens fragmentation was created as a hybrid pattern. Intraoperative measurements were of the femtosecond procedure time, the ultrasound (US) total time, effect...
Source: Lasers in Surgery and Medicine - November 24, 2017 Category: Laser Surgery Authors: Bilgehan Sezgin Asena, Mahmut Kaskaloglu Tags: Clinical Reports Source Type: research

Nevi and lasers: Practical considerations
Lasers are increasingly used for elective ablation of melanocytic nevi (MN). However, the associated risks of treating MN with lasers are debated and not well studied. Theoretical risks include inadvertently treating a melanoma mistaken for a nevus, the inability to remove all nevus cells and the possibility for residual cells to undergo malignant transformation, and the difficulty in clinically monitoring the remnant nevus for melanoma progression. Additional concerns include the morphological suitability of a lesion for laser removal and managing patients’ expectations about the variable cosmetic outcomes. These po...
Source: Lasers in Surgery and Medicine - November 21, 2017 Category: Laser Surgery Authors: Tova Rogers, Andrew C. Krakowski, Maria L. Marino, Anthony Rossi, Richard R. Anderson, Ashfaq A. Marghoob Tags: Letter to the Editor Source Type: research

Complications from microfocused transcutaneous ultrasound: Case series and review of the literature
ConclusionDespite their rarity, serious adverse events secondary to MFUS are nevertheless possible and may be underreported. Early management of complications includes local wound care, patient reassurance, and topical corticosteroids and/or pulsed‐dye laser to mitigate inflammatory sequelae. Other cosmetic and surgical therapies should be utilized when conservative measures have failed. Lasers Surg. Med. © 2017 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - November 20, 2017 Category: Laser Surgery Authors: Daniel P. Friedmann, Gregory P. Bourgeois, Henry H.L. Chan, Ann C. Zedlitz, Kimberly J. Butterwick Tags: Clinical Reports Source Type: research

Primary and salvage laser surgery of 341 glottic cancers —Comparison of treatment outcomes between University Head Neck Tertiary Referral Center and Local Head Neck Department
ConclusionComparison of the cohorts showed that outcomes of primary treatment were similar but there were noticeable differences in salvage treatment efficacy, favoring patients from the Tertiary Referral Center. Lasers Surg. Med. © 2017 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - November 14, 2017 Category: Laser Surgery Authors: Piotr Winiarski, Artur Lewandowski, Gra żyna Greczka, Jacek Banaszewski, Hanna Klimza, Małgorzata Wierzbicka Tags: Clinical Report Source Type: research

A comparative study with a 755  nm picosecond Alexandrite laser with a diffractive lens array and a 532 nm/1064 nm Nd:YAG With a holographic optic
ConclusionsThis study demonstrates that both fractional picosecond devices produce vacuoles in the skin, which are most likely due to areas of laser induced optical breakdown (LIOB). In the patients (skin type II–IV) we observed scatter areas of hemorrhage in the skin, due to vascular damage with the 532 nm and 1064 nm, but not with 755 nm wavelengths. Lasers Surg. Med. 9999:1–8, 2017. © 2017 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - November 7, 2017 Category: Laser Surgery Authors: Emil Tanghetti, MD, John Jennings Tags: Clinical Reports Source Type: research

Utilizing break ‐even analysis in a competitive laser market
(Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - November 7, 2017 Category: Laser Surgery Authors: Lance W. Chapman, Katherine Ferris, Christopher Zachary Tags: Letter to the Editor Source Type: research

Laser ‐assisted fixation of a nitinol stapes prosthesis
ConclusionNiTiBOND® stapes prosthesis can be closed by very little energy when appropriate energy sources like diode lasers are used, suggesting a relatively safe application in vivo. Lasers Surg. Med. © 2017 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - November 2, 2017 Category: Laser Surgery Authors: Florian Schr ötzlmair, Fabian Suchan, Thomas Pongratz, Eike Krause, Joachim Müller, Ronald Sroka Tags: Preclinical Reports Source Type: research

Subacute effects of rose Bengal/Green light cross linking on rabbit thin corneal stability and safety
ConclusionsRB and 532 nm green light irradiation effectively induced crosslinking in rabbit thin cornea, by increasing both the biomechanical stiffness and the biochemical resistance without evidence of morphological damage to the corneal endothelium or stroma. This study demonstrated the efficacy of RB‐PCL in strengthening thin cornea at four weeks after the treatment, providing a potential and possibly better option for treating corneal ectasia disorders in cases where corneal thickness is less than 400 µm. Lasers Surg. Med. © 2017 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - November 2, 2017 Category: Laser Surgery Authors: Ti Wang, Lu Zhu, Jingyin Zhu, Yinbo Peng, Nianci Shen, Yan Yu, Min Yao Tags: Preclinical Reports Source Type: research

Low ‐level red LED light inhibits hyperkeratinization and inflammation induced by unsaturated fatty acid in an in vitro model mimicking acne
Background and ObjectiveAcne vulgaris is a chronic inflammatory disease of the pilosebaceous units (PSU), associated with increased sebum production, abnormal follicular keratinization (hyperkeratinization), follicular overgrowth of Propionibacterium acnes (P. acnes), and increased inflammatory mediator release. Light therapy has attracted medical interests as a safe alternative treatment for acne. Both blue and red light therapies at high doses>10 J/cm2 have demonstrated marked effects on inflammatory acne lesions. However, few studies have investigated the effects of lower doses of light. The aim of this study ...
Source: Lasers in Surgery and Medicine - November 2, 2017 Category: Laser Surgery Authors: Wen ‐Hwa Li, Ali Fassih, Curt Binner, Ramine Parsa, Michael D. Southall Tags: Preclinical Reports Source Type: research

Commentary on significant skin tightening by closure of fractional ablative laser holes
(Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - November 1, 2017 Category: Laser Surgery Authors: Christopher Zachary Tags: Introduction Source Type: research

Introduction special dermatology plastic surgery issue January 2018
(Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - November 1, 2017 Category: Laser Surgery Authors: Roy G. Geronemus Tags: Introduction Source Type: research

Thulium laser ‐assisted endoscopic third ventriculostomy: Determining safe laser settings using in vitro model and 2 year follow‐up results in 106 patients
ConclusionsThe in vitro experiments show that under 4.0W the situation is considered safe, due to low penetration of heat, thus the chance of accidentally damaging critical structures like the basilar artery is very small. The clinical results show that the Thulium laser did not cause any bleeding of the basilar artery, and is a safe technique for laser endoscopic third ventriculostomy. Lasers Surg. Med. © 2017 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - November 1, 2017 Category: Laser Surgery Authors: Tjeerd de Boorder, Hans B. Brouwers, Herke Jan Noordmans, Peter A. Woerdeman, Kuo S. Han, Rudolf M. Verdaasdonk Tags: Clinical Reports Source Type: research

Quantification of noninvasive fat reduction: A systematic review
ConclusionsFor quantifying noninvasive fat reduction, all available methods had significant limitations: photographic comparisons were subjective; circumference or caliper measurements were confounded; ultrasound was operator dependent; MRI was expensive; computed models and simulations were in early development. As new technologies are developed, the need for reliable, accurate and practical measures of subcutaneous fat will increase. Lasers Surg. Med. © 2017 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - November 1, 2017 Category: Laser Surgery Authors: Sogyong L. Auh, Sanjana Iyengar, Alexandra Weil, Diana Bolotin, Todd V. Cartee, Jeffrey S. Dover, Ian A. Maher, Joseph F. Sobanko, Joel L. Cohen, Emily Poon, Murad Alam Tags: Clinical Reports Source Type: research

Multifunctional in vivo imaging for monitoring wound healing using swept ‐source polarization‐sensitive optical coherence tomography
ConclusionThis preliminary study suggests that the proposed multi‐functional imaging modality has a great potential to improve the understanding of wound healing through non‐invasive, serial monitoring of vascular and tissue responses to injury. Lasers Surg. Med. © 2017 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - November 1, 2017 Category: Laser Surgery Authors: Kwan S. Park, Woo June Choi, Shaozhen Song, Jingjiang Xu, Ruikang K. Wang Tags: Preclinical Reports Source Type: research

The fractional laser ‐induced coagulation zone characterized over time by laser scanning confocal microscopy—A proof of concept study
ConclusionsBy LSCM, assessment of the AFXL‐induced CZ thickness was feasible to a depth of 50 μm, and assessment of FI from a small hydrophilic test molecule, NaF in CZ and surrounding skin feasible to a depth of 160 μm. Lasers Surg. Med. © 2017 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - November 1, 2017 Category: Laser Surgery Authors: Christina A. Banzhaf, Lynlee L. Lin, Nhung Dang, Michael Freeman, Merete Haedersdal, Tarl W. Prow Tags: Preclinical Reports Source Type: research

Skin color and tissue thickness effects on transmittance, reflectance, and skin temperature when using 635 and 808  nm lasers in low intensity therapeutics
ConclusionSkin color and skin thickness affect transmittance and reflectance of laser light and must be accounted for when selecting energy dose to ensure therapeutic effectiveness at the target tissue. Skin heating appears not to be a concern when using 635 and 808 nm lasers at energy doses of up to 12 J and irradiance within American National Standards Institute standards. Photobiomodulation therapy should never exceed the American National Standards Institute recommendation for the maximum permissible exposure to the skin. Lasers Surg. Med. © 2017 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - November 1, 2017 Category: Laser Surgery Authors: Leanna Souza ‐Barros, Ghaith Dhaidan, Mikko Maunula, Vaeda Solomon, Sharon Gabison, Lothar Lilge, Ethne L. Nussbaum Tags: Basic Science Source Type: research

One ‐year follow‐up of a TRASER clinical trial for the treatment of nasal telangiectasias
ConclusionsThe TRASER effectively treats nasal telangiectasias with minimal to mild recurrence at 1‐year follow‐up. Lasers Surg. Med. © 2017 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - November 1, 2017 Category: Laser Surgery Authors: Elizabeth Geddes ‐Bruce, Selina S. Hamill, Christopher B. Zachary, Paul M. Friedman Tags: Clinical Reports Source Type: research

Relation between denaturation time measured by optical coherence reflectometry and thermal lesion depth during radiofrequency cardiac ablation: Feasibility numerical study
ConclusionsThe computer results confirmed the strong relationship between denaturation time and lesion depth and suggest that measuring denaturation time by PS‐OCR could provide information on the ablation time required to reach a specific lesion depth. Lasers Surg. Med. © 2017 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - November 1, 2017 Category: Laser Surgery Authors: Ana Gonz ález‐Suárez, David Herranz, Enrique Berjano, Jose L. Rubio‐Guivernau, Eduardo Margallo‐Balbás Tags: Basic Science Source Type: research

Nerve detection using optical spectroscopy, an evaluation in four different models: In human and swine, in ‐vivo, and post mortem
ConclusionThis study shows and discusses similarities and differences in nerve and surrounding tissues between human in vivo and post mortem, and swine in vivo and post mortem; this could support the discussion to use an alternative model to optimize and validate optical techniques for clinical nerve identification. Lasers Surg. Med. © 2017 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - November 1, 2017 Category: Laser Surgery Authors: Gerrit C. Langhout, Torre M. Bydlon, Marjolein van der Voort, Manfred M üller, Jeroen Kortsmit, Gerald Lucassen, Andrea J.R. Balthasar, Geert‐Jan van Geffen, Thorsten Steinfeldt, Henricus J.C.M. Sterenborg, Benno H.W. Hendriks, Theo J.M. Ruers Tags: Preclinical Reports Source Type: research

Challenges to laser ‐assisted drug delivery: Applying theory to clinical practice
ConclusionsChallenges in laser assisted drug delivery include unpredictability of dosing and response to therapy, possibility of inducing local and systemic reactions, and variability in treatment regimens. Lasers Surg. Med. © 2017 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - November 1, 2017 Category: Laser Surgery Authors: Omer Ibrahim, Emily Wenande, Sara Hogan, Kenneth A. Arndt, Merete Haedersdal, Jeffrey S. Dover Tags: Clinical Reports Source Type: research

Using normal and high pulse coverage with picosecond laser treatment of wrinkles and acne scarring: Long term clinical observations
ConclusionThis is a small pilot study with limited subject numbers and further data is needed to be able to make firm conclusions of observed trends, which suggest that the use of higher than standard suggested protocol number of pulses with the diffractive lens array and the 755 nm picosecond laser does not appear to offer any additional benefit over that that can already be achieved with the standard number of pulses, but also does not increase risk of detrimental post treatment effects either. Lasers Surg. Med. © 2017 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - November 1, 2017 Category: Laser Surgery Authors: Christine Dierickx Tags: Clinical Reports Source Type: research

Prospective studies of the efficacy and safety of the picosecond 755, 1,064, and 532  nm lasers for the treatment of infraorbital dark circles
ConclusionA single treatment with the fractionated picosecond 1,064/532 nm lasers did not produce a significant improvement in infraorbital hyperpigmentation. A series of three treatments with the fractionated picosecond 755 nm laser resulted in significant improvement in hyperpigmentation. Lasers Surg. Med. © 2016 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - November 1, 2017 Category: Laser Surgery Authors: Monique J. Vanaman Wilson, Isabela T. Jones, Joanna Bolton, Lisa Larsen, Douglas C. Wu, Mitchel P. Goldman Tags: Clinical Reports Source Type: research

Successful and safe use of Q ‐switched lasers in the treatment of nevus of Ota in children with phototypes IV–VI
ConclusionTreatment of nevus of Ota with Q‐switched lasers in children with skin of color, without general anesthesia or sedation, is safe and effective. Early intervention should be encouraged for better efficacy and to prevent psychosocial distress in later childhood and adulthood. Lasers Surg. Med. © 2017 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - November 1, 2017 Category: Laser Surgery Authors: Daniel A. Belkin, Hana Jeon, Elliot Weiss, Jeremy A. Brauer, Roy G. Geronemus Tags: Clinical Reports Source Type: research

A Comparitive study with a 755  nm picosecond Alexandrite laser with a diffractive lens array and a 532 nm/1,064 nm Nd:YAG with a holographic optic
ConclusionsThis study demonstrates that both fractional picosecond devices produce vacuoles in the skin, which are most likely due to areas of laser induced optical breakdown (LIOB). In the patients (skin type II–IV) we observed scatter areas of hemorrhage in the skin, due to vascular damage with the 532 nm and 1,064 nm, but not with 755 nm wavelengths. Lasers Surg. Med. © 2017 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - November 1, 2017 Category: Laser Surgery Authors: Emil Tanghetti, John Jennings Tags: Clinical Reports Source Type: research

In ‐line optical fiber metallic mirror reflector for monolithic common path optical coherence tomography probes
ConclusionWe developed a miniaturized monolithic inline fiber mirror‐based common path probe for optical coherence tomography. Owing to its simplicity, our design will be helpful in endoscopic applications that require high‐resolution probes in a compact form factor while reducing system complexity. Lasers Surg. Med. © 2017 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - November 1, 2017 Category: Laser Surgery Authors: Kanwarpal Singh, Rohith Reddy, Gargi Sharma, Yogesh Verma, Joseph A. Gardecki, Guillermo Tearney Tags: Basic Science Source Type: research

Diagnostic validity of ICDAS II, VistaProof and a combination of these two methods. An in vitro study in pre ‐cavitated lesions
ConclusionsICDAS II criteria and the assistance provided by VistaProof increase the ability to diagnose incipient lesions and take early action to treat them. It is important to combine the two in order to obtain more significant results, considering non‐opperative treatments for non‐cavitated lesions diagnosed. Lasers Surg. Med. © 2017 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - November 1, 2017 Category: Laser Surgery Authors: Jos é Enrique Iranzo‐Cortés, María Almarche‐Tarazona, José María Montiel‐Company, José Manuel Almerich‐Silla Tags: Preclinical Reports Source Type: research

Significant skin ‐tightening by closure of fractional ablative laser holes
Background and ObjectiveAblative fractional laser treatment uses thousands of very small laser beam wounds to damage a fraction of the skin, which stimulates tissue remodeling. Each open micro‐wound heals without scarring, but the amount of skin tightening achieved is limited. This animal study was performed to test the hypothesis that immediate temporary closure of fractional laser wounds could increase skin tightening after fractional ablative laser treatment. Materials and MethodsFour adult swine were used for the study; 98 square test sites (3 × 3 cm) were tattooed on the abdomen and flanks...
Source: Lasers in Surgery and Medicine - October 23, 2017 Category: Laser Surgery Authors: Elisabeth Russe, Martin Purschke, Wikunda Limpiangkanan, William A. Farinelli, Ying Wang, Apostolos G. Doukas, Fernanda H. Sakamoto, Gottfried Wechselberger, Richard Rox Anderson Tags: Preclinical Reports Source Type: research

News & Announcements
(Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - October 16, 2017 Category: Laser Surgery Tags: News & Announcements Source Type: research

Table of Contents
(Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - October 16, 2017 Category: Laser Surgery Tags: Table of Contents Source Type: research

Online Cover, Volume 49, Number 9, November 2017
(Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - October 16, 2017 Category: Laser Surgery Tags: Online Cover Source Type: research

Ex vivo feasibility study of endoscopic intraductal laser ablation of the breast
ConclusionWe show for the first time that laser ductoscopy is technically feasible. The Thulium laser enables a superficial intraductal ablation and is a useful tool for intraductal interventions. An in vivo prospective study is needed to further demonstrate its potential. Lasers Surg. Med. © 2017 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - October 9, 2017 Category: Laser Surgery Authors: Tjeerd de Boorder, Laurien Waaijer, Paul J. van Diest, Arjen J. Witkamp Tags: Preclinical Reports Source Type: research

MRI assessment of treatment delivery for interstitial photodynamic therapy of high ‐grade glioma in a preclinical model
BackgroundHigh‐grade gliomas are primary brain tumors that have shown increasing incidence and unfavorable outcomes. Local control is crucial to the management of this pathology. Photodynamic therapy (PDT), based on the light‐induced activation of a photosensitizer (PS), achieves local treatment by inducing selective lesions in tumor tissue. ObjectivesPrevious studies have reported the outcomes of PDT for glioblastoma via immunohistological data. Our study aimed to evaluate MRI findings, including diffusion, and perfusion sequences, compared with immunohistological data from the same population to address the efficienc...
Source: Lasers in Surgery and Medicine - October 1, 2017 Category: Laser Surgery Authors: Henri ‐Arthur Leroy, Maximilien Vermandel, Bertrand Leroux, Alain Duhamel, Jean‐Paul Lejeune, Serge Mordon, Nicolas Reyns Tags: Preclinical Reports Source Type: research

Spatiotemporal modeling of laser tissue soldering using photothermal nanocomposites
ConclusionThis mathematical model can be employed to identify optimal conditions for minimizing healthy cell death while still achieving a strong seal of the ruptured tissue using laser soldering. Lasers Surg. Med. © 2017 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)
Source: Lasers in Surgery and Medicine - October 1, 2017 Category: Laser Surgery Authors: Madaline Mushaben, Russell Urie, Tanner Flake, Michael Jaffe, Kaushal Rege, Jeffrey Heys Tags: Preclinical Reports Source Type: research

Microvasculature dropout detected by the optical coherence tomography angiography in nonarteritic anterior ischemic optic neuropathy
ObjectiveTo investigate microcirculation characteristics of peripapillary superficial retina and optic disc in eyes with nonarteritic anterior ischemic optic neuropathy (NAION) using optical coherence tomography angiography (OCTA). MethodsForty‐one eyes of 30 NAION patients and 30 eyes of 30 normal subjects were evaluated with OCTA (AngioVue, Optovue). The whole vessel density, inside disc vessel density, peripapillary vessel density, and vessel densities based on the sectorial division in the nerve head mode peripapillary superficial retina and RPC mode optic disc were measured respectively. ResultsIn the NAION group, v...
Source: Lasers in Surgery and Medicine - October 1, 2017 Category: Laser Surgery Authors: Yi Song, Jing ‐yu Min, Lei Mao, Yuan‐yuan Gong Tags: Clinical Reports Source Type: research