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Source: Neurological Research
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Total 381 results found since Jan 2013.

The prognostic significance of the lipid profile after an ischemic stroke
CONCLUSIONS: The complete analysis of the lipid panel allows the determination of the prognosis of patients who suffered a stroke.PMID:34396927 | DOI:10.1080/01616412.2021.1967677
Source: Neurological Research - August 16, 2021 Category: Neurology Authors: Bruno Kusznir Vitturi Rubens Jos é Gagliardi Source Type: research

Exercise rehabilitation immediately following ischemic stroke exacerbates inflammatory injury.
CONCLUSION: Post-stroke exercise, if too early, may result in elevated levels of cell stress and increased expression of pro-inflammatory cytokines, which may amplify the tissue damage associated with cerebral ischemia/reperfusion injury. The results shed light on the manner in which exercise initiation timing may affect post-stroke rehabilitation. PMID: 28415917 [PubMed - as supplied by publisher]
Source: Neurological Research - April 20, 2017 Category: Neurology Tags: Neurol Res Source Type: research

Genetic polymorphisms of vitamin D3 metabolizing CYP24A1 and CYP2R1 enzymes in Turkish patients with ischemic stroke.
Conclusion This is the first study conducted regarding the association of CYP24A1 rs927650 and CYP2R1 rs10741657 genetic polymorphisms and ischemic stroke risk. The polymorphic genotypes of these polymorphisms, together with hypertension, diabetes, smoking, and obesity, were found as significant risk factors for ischemic stroke. PMID: 29528271 [PubMed - as supplied by publisher]
Source: Neurological Research - March 14, 2018 Category: Neurology Tags: Neurol Res Source Type: research

Effects of cerebral small vessel disease on the outcome of patients with ischemic stroke caused by large artery atherosclerosis.
DISCUSSION: CSVD can significantly influence the clinical outcome of stroke in patients with cerebral infarction caused by LAA, and the methods to capture whole brain CSVD burden cross the spectrum of changes in CSVD imaging features may be useful for patient stratification in clinical trials. Further studies should be performed to validate the relationship between CSVD related brain damage and LAA stroke. PMID: 29543130 [PubMed - as supplied by publisher]
Source: Neurological Research - March 20, 2018 Category: Neurology Tags: Neurol Res Source Type: research

Serum leptin is associated with first-ever ischemic stroke, lesion size and stroke severity in a Chinese cohort.
CONCLUSION: Serum leptin is associated with first-ever AIS, lesion size and stroke severity in a Chinese cohort. PMID: 30433860 [PubMed - as supplied by publisher]
Source: Neurological Research - November 17, 2018 Category: Neurology Tags: Neurol Res Source Type: research

Low density lipoprotein cholesterol values and outcome of stroke patients: influence of previous aspirin therapy.
Conclusion: A worse outcome was seen in stroke patients with normal levels of LDLC, but this finding was restricted to patients not under previous aspirin therapy. PMID: 32024449 [PubMed - as supplied by publisher]
Source: Neurological Research - February 8, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Human urinary kallidinogenase in treating acute ischemic stroke patients: analyses of pooled data from a randomized double-blind placebo-controlled phase IIb and phase III clinical trial.
Conclusion: HUK is safe and provides potential clinical benefits as a treatment for acute ischemic stroke. Further large post-marketing observational studies are needed. PMID: 32138624 [PubMed - as supplied by publisher]
Source: Neurological Research - March 7, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Impact of post-stroke disability and disability-perception on health-related quality of life of stroke survivors: the moderating effect of disability-severity.
CONCLUSION: Significant disability exists among stroke survivors and impaired their HRQoL while disability-severity moderating the effect. More stroke survivors have positive attitude towards their disability and impact positively on their physical health. PMID: 32573376 [PubMed - as supplied by publisher]
Source: Neurological Research - June 25, 2020 Category: Neurology Tags: Neurol Res Source Type: research

The Key Role of Initiation Timing on Stroke Rehabilitation by Remote Ischemic Conditioning with Exercise (RICE)
CONCLUSIONS: RICE, particularly RIC initiation at hour 6 post-reperfusion followed by exercise on day 5, enhanced post-stroke rehabilitation in rats.PMID:36399507 | DOI:10.1080/01616412.2022.2146259
Source: Neurological Research - November 18, 2022 Category: Neurology Authors: Qingzhu Wang Alexandra Wehbe Melissa Wills Fengwu Li Xiaokun Geng Yuchuan Ding Source Type: research

Association between polyvascular atherosclerosis and estimated glomerular filtration rate in patients with ischaemic stroke: data analysis of the patients in the Chinese National Stroke Registry.
This study evaluated the prevalence of chronic kidney disease (CKD) in ischemic stroke (IS) patients with polyvascular disease (PolyVD) and analysed the relationship between PolyVD and estimated glomerular filtration rate (eGFR) in IS patients. METHODS: Data from 9152 consecutive IS patients from the China National Stroke Registry were analysed. PolyVD was defined as patients with IS and coronary artery disease (CAD) and/or peripheral arterial disease (PAD). Chronic kidney disease was defined as eGFR < 60 mL/minute/1.73 m(2).The prevalence of CKD in IS patients with PolyVD was calculated. Logistic regression w...
Source: Neurological Research - April 22, 2015 Category: Neurology Tags: Neurol Res Source Type: research

C-reactive protein gene polymorphisms and gene-environment interactions in ischaemic stroke.
Authors: Chen Z, Yu D, Xu ZW, Li SS, Li XF, Li J, Yang X Abstract Ischaemic stroke is a heterogeneous, multifactorial disease caused by the combination of certain risk factors and genetic factors. Several single nucleotide polymorphisms (SNPs) of C-reactive protein (CRP) have been reported to be associated with serum CRP levels. However, genetic association studies have produced conflicting results regarding the association between these SNPs and ischaemic stroke. In this paper, we conducted a population-based case-control study to determine whether two SNPs of CRP (rs1800947 and rs3093059) are associated with isch...
Source: Neurological Research - May 26, 2015 Category: Neurology Tags: Neurol Res Source Type: research

Association study between C-reactive protein polymorphisms and ischaemic stroke.
CONCLUSIONS: There is no association between rs1130864 or rs3093059 and ischaemic stroke in Chinese Han population. PMID: 26039816 [PubMed - as supplied by publisher]
Source: Neurological Research - June 4, 2015 Category: Neurology Tags: Neurol Res Source Type: research