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Source: Neurological Research
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Total 381 results found since Jan 2013.
Gonadal steroids block the calpain-1-dependent intrinsic pathway of apoptosis in an experimental rat stroke model.
CONCLUSION: We conclude that a combined steroid treatment inhibits ischemia-induced neuronal apoptosis through the regulation of intrinsic pathways.
PMID: 27832728 [PubMed - as supplied by publisher]
Source: Neurological Research - November 13, 2016 Category: Neurology Tags: Neurol Res Source Type: research
Late changes in blood-brain barrier permeability in a rat tMCAO model of stroke detected by gadolinium-enhanced MRI.
DISCUSSION: Our results indicate a significant late opening of the BBB. This is important as the majority of previous studies have only characterised an early acute BBB permeability in ischemia. However, the later period of increased permeability may indicate an optimal time for drug delivery across the BBB, when it is especially suited to drugs targeting delayed processes.
PMID: 32600164 [PubMed - as supplied by publisher]
Source: Neurological Research - July 2, 2020 Category: Neurology Tags: Neurol Res Source Type: research
Long noncoding RNA ANRIL knockdown attenuates neuroinflammation following ischemic stroke via suppressing the expression of NF- κB in vitro and in vivo
CONCLUSION: our results suggest that ANRIL knockdown attenuates neuroinflammation by suppressing the expression of NF-κB both in vitro and vivo model of IS, sugguesting that ANRIL might be a potentially viable therapeutictarget to diminish neuroinflammation in IS patients.PMID:34080525 | DOI:10.1080/01616412.2021.1934317
Source: Neurological Research - June 3, 2021 Category: Neurology Authors: Ling Deng Yi Guo Jingdong Liu Sha Chen Xuan Wang Hongxia Zhao Tianrui Zuo Qingwen Hu Zhi Dong Source Type: research
Quantitative EEG provides early prediction of poor outcome in acute ischemic stroke after endovascular treatment: a preliminary study
Conclusions: Early evidence of elevated DAR and DTABR on quantitative EEG was associated with poor outcome at 90 days following EVT for AIS.PMID:34514961 | DOI:10.1080/01616412.2021.1939237
Source: Neurological Research - September 13, 2021 Category: Neurology Authors: Yunfeng Wang Dacheng Liu Jingyi Liu Chaohong Kong Zhe Zhang Wanying Duan David Dornbos Liping Liu Source Type: research
Changes of prominent vessel sign and susceptibility vessel sign in acute ischemic stroke patients with and without successful recanalization: a study based on susceptibility weighted images
CONCLUSIONS: PVS and SVS changes are influenced by the success of vascular recanalization. However, the changes are unrelated to either early clinical or imaging outcomes in AIS patients. PVS-DWI mismatch can be taken as an imaging biomarker for early clinical outcomes, both for patients with or without successful vascular recanalization.PMID:35001834 | DOI:10.1080/01616412.2021.2024729
Source: Neurological Research - January 10, 2022 Category: Neurology Authors: Zhiye Li Xiaoyan Bai Peiyi Gao Yan Lin Yi Ju Binbin Sui Source Type: research
Assessment of rehabilitation following intracerebral hemorrhage in China: findings from the Chinese stroke center alliance
This study showed that the rate of rehabilitation assessment was 74.2%, which is low. Rehabilitation assessment was associated with longer hospital stays and lower mortality. Therefore, patients with acute cerebral haemorrhage should undergo comprehensive and professional rehabilitation assessment.PMID:36126147 | DOI:10.1080/01616412.2022.2123174
Source: Neurological Research - September 20, 2022 Category: Neurology Authors: Jin-Ju Sun Yong-Mei Deng Dan-Dan Wang Hong-Qiu Gu Qi Zhou Yong-Jun Wang Zi-Xiao Li Xing-Quan Zhao Source Type: research
