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Source: Neurological Research
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Total 381 results found since Jan 2013.

Effects of transcranial direct current stimulation on lower limb function, balance and quality of life after stroke: a systematic review and meta-analysis
DISCUSSION: There is a lack of evidence in recommending the use of tDCS in isolation in the treatment of patients after stroke, aiming at improving motor function, balance and quality of life. However, it is possible that tDCS can be beneficial when associated with other therapies or interventions.PMID:37183510 | DOI:10.1080/01616412.2023.2211457
Source: Neurological Research - May 15, 2023 Category: Neurology Authors: Eloise Lima Jos é Maurício Ramos de Souza Neto Suellen Marinho Andrade Source Type: research

A pharmacoeconomic assessment of recombinant tissue plasminogen activator therapy for acute ischemic stroke in a tertiary hospital in China.
Conclusions: Intravenous rt-PA was associated with lower patients' disabilities, fewer in-hospital days, and comparable total costs compared to conservative therapy for the management of AIS. PMID: 25297471 [PubMed - as supplied by publisher]
Source: Neurological Research - December 2, 2014 Category: Neurology Tags: Neurol Res Source Type: research

Protective effect of telmisartan on neurovascular unit and inflammasome in stroke-resistant spontaneously hypertensive rats.
Discussion: These results suggest that telmisartan comprehensively protected the NVU components by reducing inflammatory reactions relative to AD in hypertensive rats, which could also preclude the risk of AD under hypertension. PMID: 25591419 [PubMed - as supplied by publisher]
Source: Neurological Research - January 18, 2015 Category: Neurology Tags: Neurol Res Source Type: research

Assessment of dose-effect and therapeutic time window in preclinical studies of rhEGF and GHRP-6 coadministration for stroke therapy.
Authors: Subirós N, Pérez-Saad HM, Berlanga JA, Aldana L, García-Illera G, Gibson CL, García-Del-Barco D Abstract BACKGROUND: Stroke continues to be a leading cause of mortality and morbidity worldwide, and novel therapeutic options for ischaemic stroke are urgently needed. In this context, drug combination therapies seem to be a viable approach, which has not been fully explored in preclinical studies. OBJECTIVES: In this work, we assessed the dose-response relationship and therapeutic time window, in global brain ischaemia, of a combined therapeutic approach of recombinant human epidermal growth factor (E...
Source: Neurological Research - August 29, 2015 Category: Neurology Tags: Neurol Res Source Type: research

Reduction in spasticity in stroke patient with paraffin therapy.
CONCLUSION: Paraffin therapy may be a kind of noninvasive, promising method to reduce spasticity of stroke patients. PMID: 27876449 [PubMed - as supplied by publisher]
Source: Neurological Research - November 24, 2016 Category: Neurology Tags: Neurol Res Source Type: research

Dl-3-n-butylphthalide can improve the cognitive function of patients with acute ischemic stroke: a prospective intervention study.
DISCUSSION: Dl-3-n-butylphthalide could significantly improve the cognitive function of AIS patients 1 month after stroke. Hcy was involved in the incidence of VD 1 month after AIS. However, further studies are necessary because of differences between groups at baseline. PMID: 28145815 [PubMed - as supplied by publisher]
Source: Neurological Research - February 2, 2017 Category: Neurology Tags: Neurol Res Source Type: research

Effects of neuroserpin on clinical outcomes and inflammatory markers in Chinese patients with acute ischemic stroke.
CONCLUSIONS: A larger decrease in NSP levels related to lower levels of inflammatory marker, while higher NSP levels were associated with lower inflammatory markers and better functional outcomes. Decreasing the infarct size may play a role in this process. These results provide more evidence of the neuroprotective effect of NSP in cerebral ischemic patients. Decrease in the Serum NSP level and NSP level at admission may be considered as potential predictive factors for outcome of acute ischemic stroke. PMID: 28738762 [PubMed - as supplied by publisher]
Source: Neurological Research - July 26, 2017 Category: Neurology Tags: Neurol Res Source Type: research

Association of circulating blood HMGB1 levels with ischemic stroke: a systematic review and meta-analysis.
CONCLUSIONS: This meta-analysis demonstrates that circulating blood HMGB1 levels elevate in IS and higher HMGB1 levels may indicate a more serious condition. PMID: 30015578 [PubMed - as supplied by publisher]
Source: Neurological Research - July 19, 2018 Category: Neurology Tags: Neurol Res Source Type: research

Effect of a novel designed intensive patient care program on cognitive impairment, anxiety, depression as well as relapse free survival in acute ischemic stroke patients: a randomized controlled study.
Conclusions: IPCP presents with a positive influence on improving cognitive impairment and decreasing anxiety as well as depression, while a less effect on improving RFS in AIS patients. Abbreviation: IPCP: intensive patient care program; RFS: relapse free survival; AIS: acute ischemic stroke; MRA: magnetic resonance angiography; ITT: intention-to-treat; LOCF: last observation carried forward. PMID: 31266412 [PubMed - as supplied by publisher]
Source: Neurological Research - July 4, 2019 Category: Neurology Tags: Neurol Res Source Type: research