Filtered By:
Source: Brain Research
This page shows you your search results in order of date. This is page number 2.
Order by Relevance | Date
Total 501 results found since Jan 2013.
"Lifting Yang to Dredging Du Meridian Manipulation" acupuncture alleviates cerebral ischemia-reperfusion injury by mediating the NF- κB pathway
CONCLUSIONS: LYDD acupuncture ameliorates cerebral ischemia-reperfusion injury by inhibiting NF-κB pathway activity.PMID:37414270 | DOI:10.1016/j.brainres.2023.148477
Source: Brain Research - July 6, 2023 Category: Neurology Authors: Xiahui Zhang Lei Ma Meifang Liu Tao Zhu Zhilin Huang Youlong Xiong Ziyi Wang Jing Shi Source Type: research
Moderate-intensity cardiovascular exercise performed before motor practice attenuates offline implicit motor learning in stroke survivors but not age-matched neurotypical adults
Exp Brain Res. 2023 Jul 3. doi: 10.1007/s00221-023-06659-w. Online ahead of print.ABSTRACTThe acute impact of cardiovascular exercise on implicit motor learning of stroke survivors is still unknown. We investigated the effects of cardiovascular exercise on implicit motor learning of mild-moderately impaired chronic stroke survivors and neurotypical adults. We addressed whether exercise priming effects are time-dependent (e.g., exercise before or after practice) in the encoding (acquisition) and recall (retention) phases. Forty-five stroke survivors and 45 age-matched neurotypical adults were randomized into three sub-group...
Source: Brain Research - July 3, 2023 Category: Neurology Authors: Giordano Marcio Gatinho Bonuzzi Flavio Henrique Bastos Nicolas Schweighofer Eric Wade Carolee Joyce Winstein Camila Torriani-Pasin Source Type: research
Oral probiotic therapy improves motor function in a rodent model of sensorimotor stroke
In this study, we examined the effect of post-stroke oral probiotic therapy on motor behavior in the pre-clinical mouse endothelin-1 (ET-1) model of sensorimotor stroke. We found that post-stroke oral probiotic therapy with Cerebiome® (Lallemand, Montreal, Canada), containing B. longum R0175 and L. helveticus R0052, improved functional recovery and changed the composition of the post-stroke gut microbiota. Interestingly, oral Cerebiome® administration did not result in alterations of lesion volume or the number of CD8+/Iba1+ cells in the injured tissue. Overall, these findings suggest that probiotic treatment following i...
Source: Brain Research - June 26, 2023 Category: Neurology Authors: E Daniele Y Nazer I Kortebi D Lozano Casasbuenas Y Fan M Trinh T A Tompkins M Faiz Source Type: research
The neuroprotective role of prolonged normobaric oxygenation applied during ischemia and in the early stage of reperfusion in cerebral ischemic rats
CONCLUSIONS: The mechanism underlying the neuroprotective role of i/rNBO involved prolonged NBO treatment for cerebral ischemia, suggesting that i/rNBO may allow expansion of the time window for NBO application in stroke patients following vascular recanalization.PMID:37328087 | DOI:10.1016/j.brainres.2023.148464
Source: Brain Research - June 16, 2023 Category: Neurology Authors: Daiquan Gao Shuhua Yuan Xunming Ji Yingying Su Zhifeng Qi Source Type: research
Altered dynamic functional network connectivity states in patients with acute basal ganglia ischemic stroke
CONCLUSIONS: AIS not only altered the interaction between the different dynamic networks but also promoted characteristic alterations in the temporal and topological features of large-scale dynamic network connectivity.PMID:37201623 | DOI:10.1016/j.brainres.2023.148406
Source: Brain Research - May 18, 2023 Category: Neurology Authors: Zhongming Li Zhimin Wang Dairong Cao Ruixiong You Jianping Hu Source Type: research
DUSP10 alleviates ischemic stroke-induced neuronal damage by restricting p38/JNK pathway
This study aimed to investigate the effect of on apoptosis in primary cortical neurons exposed to oxygen-glucose deprivation and reoxygenation (OGD/R) and mice suffered from transient middle cerebral artery occlusion and reperfusion (MCAO/R). The results showed that DUSP10 overexpression improved survival and reduced apoptosis in neurons subjected to OGD/R, which was manifested by decreased apoptotic proteins (cleaved caspase 3 and bax) and TUNEL+ cells, as well as increased the anti-apoptotic protein (bcl-2). DUSP10 overexpression inhibited the p38/JNK signaling pathway after OGD/R treatment, whilst DUSP10 knockdown had o...
Source: Brain Research - May 10, 2023 Category: Neurology Authors: Ni-Na Song Ying Zhao Chuang Sun Jun Zhang Guang-Jun Lin Xiao-Wei Yin Chun-Ye Ma Source Type: research
Acquired heat acclimation in rats subjected to physical exercise under environmental heat stress alleviates brain injury caused by exertional heat stroke
Conclusions: This HA model can ameliorate brain injury of EHS by reducing cerebral edema and cell apoptosis, offering experimental evidence for EHS prophylaxis.PMID:37150340 | DOI:10.1016/j.brainres.2023.148393
Source: Brain Research - May 7, 2023 Category: Neurology Authors: Xin Li Fan Xv Li-Zhen Ma Ling Xing Jin-Bao Zhao Wei-Jia Zhi Li-Feng Wang Yang Wang Han-Ding Mao Shu-Yuan Liu Ya-Hua Liu Qing Song Source Type: research
Else_BRB_110660Docosahexaenoic acid promotes M2 microglia phenotype via activating PPAR γ-mediated ERK/AKT pathway against cerebral ischemia-reperfusion injury
Brain Res Bull. 2023 May 4:110660. doi: 10.1016/j.brainresbull.2023.110660. Online ahead of print.ABSTRACTIn ischemia-reperfusion stroke, microglia play a dual role in brain injury as well as brain repair, and promoting their switch from a pro-inflammatory M1 phenotype to an anti-inflammatory M2 phenotype is considered to be a potential therapeutic strategy. Docosahexaenoic acid (DHA) is an essential long-chain omega-3 polyunsaturated fatty acid that exhibits potent anti-inflammatory properties in the acute phase of ischemic stroke, but its effect on microglia polarization is unknown. Thus, the objective of this study was ...
Source: Brain Research - May 6, 2023 Category: Neurology Authors: Huijing Lv Shuai Jia Yanan Sun Meng Pang E Lv Xiangling Li Qinghui Meng Yanqiang Wang Source Type: research
Impairments and Compensation in String-pulling After Middle Cerebral Artery Occlusion in the Rat
This study describes middle cerebral artery occlusion (MCAO) dependent changes in the bilaterally dependent hand use behavior of string-pulling in the rat. The task involves making hand-over-hand movements to pull down a string that contains a food reward attached to its end. MCAO rats missed the string more often with both hands than Sham rats. When the string was missed on the contralateral to MCAO body side, rats continued to cycle through subcomponents of string-pulling behavior as if the string were grasped in the hand. Rats also failed to make a grasping motion with the contralateral to MCAO hand when the string was ...
Source: Brain Research - May 5, 2023 Category: Neurology Authors: Muriel Hart Ashley A Blackwell Ian Q Whishaw Douglas G Wallace Joseph L Cheatwood Source Type: research
