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Source: Neurological Sciences
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Total 431 results found since Jan 2013.
Acute ischemic stroke and COVID-19 pandemic in Brazil: a comparative study of frequency and risk factors before and during SARS-CoV-2 era
ConclusionsHospital admissions for AIS decreased in the COVID-19 pandemic, mostly during months of higher incidences of new COVID-19 cases. When the incidence of admissions diminished, an increase in the severity of AIS was observed, characterized by larger areas. These findings might contribute to other similar referral centers in managing public policies related to stroke.
Source: Neurological Sciences - February 9, 2022 Category: Neurology Source Type: research
In-hospital and out-of-hospital stroke in patients with COVID-19: two different diseases?
ConclusionsPatients with stroke and COVID-19 had higher mortality compared to patients without COVID-19. Among patients with COVID-19 those with out-of-hospital stroke had better outcome and fewer blood test abnormalities compared to patients with in-hospital stroke.
Source: Neurological Sciences - January 22, 2022 Category: Neurology Source Type: research
Acute telestroke evaluations during the COVID-19 pandemic
This study is a retrospective database review of all telestroke requests at one academic vascular neurology center telestroke network with seven remote sites in the USA between March 15 and April 30, 2020. Data were compared with historical cohort spanning same time frame in 2019 using parametric or nonparametric methods as appropriate. Among telestroke requests, characteristics of age, gender, race/ethnicity, National Institutes of Health Stroke Scale (NIHSS), primary diagnosis of AIS or transient ischemic attack (TIA), and number of patients receiving intravenous alteplase (IV-rtPA) and endovascular therapy (ET) were rec...
Source: Neurological Sciences - January 22, 2022 Category: Neurology Source Type: research
FLAIR vascular hyperintensity predicts early neurological deterioration in patients with acute ischemic stroke receiving endovascular thrombectomy
AbstractFluid-attenuated inversion recovery vascular hyperintensity (FVH) is frequently observed in patients with acute ischemic stroke (AIS). FVH is associated with functional outcome at 3 months in AIS patients receiving endovascular thrombectomy. In the present study, we assessed whether FVH predicted early neurological deterioration (END) and hemorrhagic transformation (HT) within 72 h in AIS patients receiving endovascular thrombectomy. We retrospectively analyzed 104 patients with acute internal-carotid-artery or proximal middle-cerebral-artery occlusion within 16 h after symptom onset. Before thrombectomy, all p...
Source: Neurological Sciences - January 22, 2022 Category: Neurology Source Type: research
Neurological emergency at the COVID-19 pandemic: report from a referral hospital in Eastern Piedmont, Italy
We described how the flow of neurological emergencies was affected by the pandemic impact.MethodsWe analyzed accesses to the Emergency Department (ED) of the “Maggiore della Carità” Hospital, Piedmont, Italy, during a period of 8 months (COVID time; March to May 2020 and October 2020 to February 2021) and analyzed the admissions to the Neurology Unit and the underlying diagnosis. We also evaluated potential changes in the treatment of acute ischemi c stroke in the same period. These variables were compared with two equivalent periods of time (2019–2020; 2018–2019).ResultsDuring the COVID time, there was a clear-c...
Source: Neurological Sciences - January 18, 2022 Category: Neurology Source Type: research
Effects of stroke etiology on angiographic success in patients undergoing mechanical thrombectomy
ConclusionRecanalization success and clinical outcomes did not differ significantly in patients with LVAD and those with cardioembolic etiology. However, mortality rate was higher in patients with atherosclerotic etiology, due to the complexity of the procedure and the high rate of reocclusion.
Source: Neurological Sciences - January 17, 2022 Category: Neurology Source Type: research
Neurological toll of COVID-19
AbstractThe first case of coronavirus illness was discovered in Wuhan, China, in January 2020 and quickly spread worldwide within the next couple of months. The condition was initially only linked with respiratory disorders. After the evolution of various variants of the SARS-CoV-2, the critical impact of the virus spread to multiple organs and soon, neurological disorder manifestations started to appear in the infected patients. The review is focused on the manifestation of various neurological disorders linked with both the central nervous system and peripheral nervous system. Disorders such as cytokine release syndrome,...
Source: Neurological Sciences - January 16, 2022 Category: Neurology Source Type: research
Stroke and kidney stones: common predisposing factors in viewpoint of Persian medicine
Source: Neurological Sciences - January 15, 2022 Category: Neurology Source Type: research
Arterial intracranial thrombosis as the first manifestation of vaccine-induced immune thrombotic thrombocytopenia (VITT): a case report
We describe a severe case of vaccine-induced immune thrombotic thrombocytopenia (VITT) after the first dose of the ChAdOx1 nCoV-19 vaccine leading to massive ischemic stroke.MethodsA 42-year-old woman developed acute left hemiparesis (NIHSS 12) 9 days after the first vaccine dose.ResultsThe blood tests revealed low platelets (70 103/ μL) and severe increment of D-dimer (70,745 ng/mL FEU). Brain non-contrast computed tomography and multiphasic CT angiography demonstrated a right middle cerebral artery occlusion. The patient was treated with primary thrombectomy, steroids, immunoglobulin, and fondaparinux. Despite the tr...
Source: Neurological Sciences - January 13, 2022 Category: Neurology Source Type: research
The European Portuguese version of the Oxford Cognitive Screening (OCS-Pt): a screening test for acute stroke patients
AbstractIn Portugal, there is no gold standard test to assess acute stroke patients in the hospital context. However, cognitive deficits are common after a stroke episode and are followed by a negative impact on a patient ’s quality of life and rehabilitation. Here, we first aimed to adapt the Oxford Cognitive Screening to European Portuguese speakers (OCS-Pt), develop normative data cut-offs, and report the psychometric properties of the OCS-Pt. The second aim was to test the incidence of impairments in acute stro ke patients. We tested 137 healthy participants aged between 25 and 92 years old, and we report normative ...
Source: Neurological Sciences - January 13, 2022 Category: Neurology Source Type: research
Transcranial magnetic stimulation implementation on stroke prognosis
DiscussionMotor evoked potentials (MEPs) recording is indicative of a favorable prognosis concerning the motor recovery of upper and lower extremities ’ weakness, swallowing and speech difficulties, and the patient’s general functional outcome. On the contrary, MEP absence is usually associated with poor prognosis. Relative correlations have also been made among other TMS variants (motor threshold, MEP amplitude, central motor conduction time) and the expected recovery rate. Overall, TMS represents a non-invasive, fast, safe, and reproducible prognostic tool poststroke that could resolve prognostic uncertainties in cases of stroke.
Source: Neurological Sciences - November 30, 2021 Category: Neurology Source Type: research
Mechanical thrombectomy in acute ischemic stroke due to large vessel occlusion in the anterior circulation and low baseline National Institute of Health Stroke Scale score: a multicenter retrospective matched analysis
ConclusionsOur experience is in favor of a potential benefit of MT also in patients with LVO and a NIHSS score ≤ 5 at the time of groin puncture. Nonetheless, this issue waits for a clear-cut recommendation in a dedicated clinical trial.
Source: Neurological Sciences - November 29, 2021 Category: Neurology Source Type: research
The predictive value of lesion and disconnectome loads for upper limb motor impairment after stroke
ConclusionsThe combination of the CST lesion load and baseline upper limb motor impairment would provide a tailored fusion of imaging and clinical measures for more accurate motor outcome prediction.
Source: Neurological Sciences - November 29, 2021 Category: Neurology Source Type: research
The effect of music therapy on language recovery in patients with aphasia after stroke: a systematic review and meta-analysis
ConclusionsMusic therapy can improve functional communication, repetition, and naming in patients with post-stroke aphasia, but did not significantly improve comprehension.Trial registrationCRD42021251526
Source: Neurological Sciences - November 24, 2021 Category: Neurology Source Type: research
Lower uric acid level may be associated with hemorrhagic transformation after intravenous thrombolysis
ConclusionsThese findings suggest that low levels of UA may be associated with HT after IVT.
Source: Neurological Sciences - November 24, 2021 Category: Neurology Source Type: research
