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Source: Neurological Sciences

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Total 431 results found since Jan 2013.

Cognitive impairment before and after intracerebral haemorrhage: a systematic review
ConclusionCognitive impairment and dementia affected almost one-third of patients, whether assessed pre or post ICH.
Source: Neurological Sciences - December 3, 2019 Category: Neurology Source Type: research

Practical approach to respiratory emergencies in neurological diseases
AbstractMany neurological diseases may cause acute respiratory failure (ARF) due to involvement of bulbar respiratory center, spinal cord, motoneurons, peripheral nerves, neuromuscular junction, or skeletal muscles. In this context, respiratory emergencies are often a challenge at home, in a neurology ward, or even in an intensive care unit, influencing morbidity and mortality. More commonly, patients develop primarily ventilatory impairment causing hypercapnia. Moreover, inadequate bulbar and expiratory muscle function may cause retained secretions, frequently complicated by pneumonia, atelectasis, and, ultimately, hypoxe...
Source: Neurological Sciences - December 1, 2019 Category: Neurology Source Type: research

Ipsilateral acute ischemic stroke in a patient with concomitant intracerebral hemorrhage successfully treated with mechanical thrombectomy
Source: Neurological Sciences - November 11, 2019 Category: Neurology Source Type: research

Influences of genetic variants on stroke recovery: a meta-analysis of the 31,895 cases
ConclusionsWe demonstrate that recovery of AIS was unfavourably associated with variants of BDNF and CYP2C19 genes whilst recovery of ICH was unfavourably associated withAPOE4 gene.
Source: Neurological Sciences - November 11, 2019 Category: Neurology Source Type: research

Concomitant diabetes or hypertension with metabolic syndrome on the extent of intracranial atherosclerotic stenosis
ConclusionMetS and DM along with hypertension is associated with more extensive ICAS than MetS and hypertension or MetS only. Patients with MetS at high risk of hypertension and DM may benefit from therapeutic lifestyle changes to prevent stroke risk.
Source: Neurological Sciences - November 4, 2019 Category: Neurology Source Type: research

“Accent issue”: foreign accent syndrome following ischemic stroke
In conclusion, FAS is a rare motor speech disorder, often related to cerebrovascular accidents involving critical regions in the dominant hemisphere. In addition, the present case adds further evidence to the role of the left primary motor cortex in modulation of prosody. In rare cases FAS can be the only sign of stroke or can appear after recovery from post-stroke aphasia.
Source: Neurological Sciences - October 28, 2019 Category: Neurology Source Type: research

Diagonal earlobe crease (Frank ’s sign) and increased risk of cerebrovascular diseases: review of the literature and implications for clinical practice
AbstractDiagonal earlobe crease (DELC) or Frank ’s sign is a diagonal crease in the earlobe that extends diagonally from the tragus to the edge of the auricle with an angle of approximately 45°. Although its presence increases with advancing age, several studies have shown an independent association between DELC and cardiovascular diseases as well as peripheral vascular diseases. DELC has also been demonstrated to increase the risk of cerebrovascular events (mostly ischaemic stroke), probably through atherosclerotic mechanisms. A systematic literature search was conducted using PubMed and Embase to identify studies inve...
Source: Neurological Sciences - October 22, 2019 Category: Neurology Source Type: research

Acute ischemic stroke due to endocarditis from Brucella infection
Source: Neurological Sciences - October 21, 2019 Category: Neurology Source Type: research

Obstructive sleep apnea and ischemic stroke: a risk assessment
Source: Neurological Sciences - September 14, 2019 Category: Neurology Source Type: research

The inter-rater reliability of the Italian version of Aphasia Rapid Test (ART) for acute ischemic stroke
ConclusionsThis study showed that the cross-cultural adaptation of the French version of the ART was successful in an Italian-speaking population.
Source: Neurological Sciences - September 14, 2019 Category: Neurology Source Type: research

Posterior circulation ischemic stroke —a review part II: imaging and acute treatment
AbstractPosterior circulation strokes affect the vertebrobasilar arterial system, account for about 20 –25% of all ischemic strokes, and are a significant cause of patient disability and mortality. Diagnosis can be challenging; clinical presentation and common pitfalls facing posterior circulation stroke have been discussed elsewhere. In the first part of the review, we focus on the imaging, discus sing the information that can be gathered through a correct selection and interpretation of different possible studies helping to achieve an early diagnosis and to select the best medical treatment. In the second part of the r...
Source: Neurological Sciences - September 14, 2019 Category: Neurology Source Type: research

Low homoarginine/SDMA ratio is associated with poor short- and long-term outcome after stroke in two prospective studies
ConclusionThese results from two prospective stroke studies reveal that hArg/SDMA ratio could prove a valuable blood-based biomarker to discriminate patients with poor short- and long-term outcome, increased neurological impairment, and severe disability after stroke.
Source: Neurological Sciences - September 2, 2019 Category: Neurology Source Type: research

Hesperidin reduces adverse symptomatic intracerebral hemorrhage by promoting TGF- β1 for treating ischemic stroke using tissue plasminogen activator
AbstractTreatment with recombinant tissue plasminogen activator (rt-PA) is the most effective therapeutic option against brain ischemic stroke at the present time. However, elevated incidence of symptomatic intracerebral hemorrhage (SIH) greatly hinders ideal treatment outcome of rt-PA. We sought to assess the impacts of hesperidin on SIH following rt-PA therapies. Patients with ischemic stroke were assigned into two groups in a random fashion, to receive either rt-PA + placebo (Pc) or rt-PA + hesperidin. Treatment outcome was evaluated 24  h after the initial reperfusion using the transcranial Doppler ultrasonography (TC...
Source: Neurological Sciences - September 1, 2019 Category: Neurology Source Type: research

Association of plasma trimethylamine-N-oxide levels with post-stroke cognitive impairment: a 1-year longitudinal study
ConclusionsThis study demonstrated that increasing plasma level of TMAO may be associated with PSCI.
Source: Neurological Sciences - August 15, 2019 Category: Neurology Source Type: research

Genetic variants within Ninjurin 2 gene are associated with risk of ischemic stroke in Iranian population
AbstractPrevious genetic and epidemiological studies have shown the contribution of genetic factors in conferring the risk of ischemic stroke. Among the acknowledged risk factors of stroke are the single nucleotide polymorphisms (SNPs) nearNinjurin 2 (NINJ2) gene which encodes a surface adhesion protein. In the current study, we investigated the role of two SNPs near this gene in ischemic stroke in Iranian population. The frequency of the A allele of the rs11833579 was significantly lower in cases compared with controls (OR (95% CI)  = 0.68 (0.54–0.86), adjustedP value  = 0.002). The rs11833579 was significantly ...
Source: Neurological Sciences - August 1, 2019 Category: Neurology Source Type: research