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Total 216 results found since Jan 2013.

Do E-Cigarettes Damage Blood Vessels?
MONDAY, Sept. 11, 2017 -- Nicotine in e-cigarettes may cause stiffened arteries, which can lead to an increased risk for heart attack and stroke, a small Swedish study suggests. With the dramatic increase in e-cigarette use ( " vaping " ) over the past...
Source: Drugs.com - Daily MedNews - September 11, 2017 Category: General Medicine Source Type: news

Delayed Varenicline Administration Reduces Inflammation and Improves Forelimb Use Following Experimental Stroke
Pharmacological activation of the cholinergic anti-inflammatory pathway (CAP), specifically by activating α7 nicotinic acetylcholine receptors, has been shown to confer short-term improvements in outcome. Most studies have investigated administration within 24 hours of stroke, and few have investigated drugs approved for use in human patients. We investigated whether delayed administration of varenicli ne, a high-affinity agonist at α7 nicotinic receptors and an established therapy for nicotine addiction, decreased brain inflammation and improved functional performance in a mouse model of experimental stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - August 7, 2017 Category: Neurology Authors: Siyi Chen, Laura Bennet, Ailsa L. McGregor Source Type: research

Smoking and blood pressure: A complex relationship.
Abstract Hypertension and tobacco smoking are two major modifiable risk factors for atheromatous disease and its cardiovascular complications. If systolic hypertension (SBP≥140mmHg and DBP<90mmHg) is the leading risk factor for stroke, smoking (nicotine) has a more powerful impact on coronary events, aortic aneurysms, and peripheral artery disease. Smoking can transiently modify the regulation of blood pressure (BP) by a swift effect on the autonomic nervous system. It also accelerates arterial aging, which plays a role in chronic hypertension. Chronic sympathetic activation induced by tobacco smoking also ha...
Source: Presse Medicale - July 28, 2017 Category: General Medicine Authors: Madika AL, Mounier-Vehier C Tags: Presse Med Source Type: research

Mental and Physical Health Conditions in US Combat Veterans: Results From the National Health and Resilience in Veterans Study.
Conclusions: Compared to noncombat veterans in the United States, combat veterans have elevated rates of PTSD, suicide attempt, stroke, and chronic pain independent of other sociodemographic, military, and mental health factors. Younger combat veterans have elevated rates of PTSD, suicidal ideation, and migraine headaches, while older combat veterans have elevated rates of heart disease and heart attack. These results characterize the population-based burden of mental and physical health conditions in combat veterans. They further underscore the importance of age- and condition-sensitive screening, monitoring, and treatmen...
Source: The Primary Care Companion for CNS Disorders - June 30, 2017 Category: Primary Care Tags: Prim Care Companion CNS Disord Source Type: research

Offsetting the impact of smoking and e-cigarette vaping on the cerebrovascular system and stroke injury: Is Metformin a viable countermeasure?
In this study we provide additional in vivo evidence showing that MF can effectively reduce the oxidative and inflammatory risk for stroke and attenuate post-ischemic brain injury promoted by TS and e-Cig vaping. Our data also suggest that MF administration could be extended as prophylactic care during the time window required for the renormalization of the risk levels of stroke following smoking cessation thus further studies in that direction are warrated. Graphical abstract
Source: Redox Biology - June 22, 2017 Category: Biology Source Type: research

Chris Cornell: When Suicide Doesn't Make Sense
By Julie A. Fast Sometimes, people commit suicide and it does make some sense. It’s scary and upsets our world, but on a basic level we think we understand. The suicide of Robin Williams comes to mind. He had a history of depression and his health was failing. Oh how we all wish he could have found more help, but I don’t think it was as much surprising as it was devastating and sad for the millions who loved him when he died. Then there are suicides that make no sense. They don’t fit in the current life of the person or fit what the person is actually saying about life in public. The partner or other love...
Source: Healthy Living - The Huffington Post - May 18, 2017 Category: Consumer Health News Source Type: news

Role of Nrf2 and protective effects of Metformin against tobacco smoke-induced cerebrovascular toxicity
Publication date: August 2017 Source:Redox Biology, Volume 12 Author(s): Shikha Prasad, Ravi K. Sajja, Mohammad Abul Kaisar, Jee Hyun Park, Heidi Villalba, Taylor Liles, Thomas Abbruscato, Luca Cucullo Cigarette smoking (CS) is associated with vascular endothelial dysfunction in a causative way primarily related to the TS content of reactive oxygen species (ROS), nicotine, and inflammation. TS promotes glucose intolerance and increases the risk of developing type-2 diabetes mellitus (2DM) with which it shares other pathogenic traits including the high risk of cerebrovascular and neurological disorders like stroke via ROS ...
Source: Redox Biology - February 15, 2017 Category: Biology Source Type: research

Cross-sectional study of the ankle-brachial index and cardiovascular risk factors in postmenopausal women.
CONCLUSIONS: There is no evidence that stricter criteria for the assessment of ABI better represent the vascular status in the female population. PMID: 28150285 [PubMed - as supplied by publisher]
Source: Polish Heart Journal - February 1, 2017 Category: Cardiology Authors: Wierzchowski P, Dereziński T, Migdalski A, Woda Ł, Wąsikowska B, Jakubowski G, Jawień A Tags: Kardiol Pol Source Type: research

Nine Easy Ways to Gain Control of Your Health in Your Forties
What lifestyle changes should you make to stay healthy through your 40s? originally appeared on Quora - the knowledge sharing network where compelling questions are answered by people with unique insights. Answer by Keck Medicine of USC, 500+ internationally renowned doctors at a leading academic medical center, on Quora: Getting older has its perks. Chances are you're more confident, have more direction and a defined sense of self. While your health is likely not a primary concern, it's important to take steps now to stop subtle changes before they become major health issues. Your 40s is the decade that your habits sta...
Source: Healthy Living - The Huffington Post - January 9, 2017 Category: Consumer Health News Source Type: news

Behind the Headlines 2016 Quiz of the Year
In 2014, Behind the Headlines has covered more than 500 health stories that made it into the mainstream media. If you've been paying attention you should find this quiz easy and fun. Why not test your knowledge of 2014's health news with our month-by-month quiz? Answers are at the foot of the page (no peeking!).   In January 2016's health news... In a controversial study, monkeys were genetically engineered to develop what disorder? 1) Sex addiction 2) Bi-polar disorder 3) Autism In a similarly controversial study, what psychological condition was dismissed as a "myth" 1) Seasonal affective disorder...
Source: NHS News Feed - December 5, 2016 Category: Consumer Health News Tags: Special reports Source Type: news

How to Quit Smoking
By Stacy Simon Tobacco use remains the single largest preventable cause of disease and premature death in the United States. Since the release of the Surgeon General’s Report on Smoking and Health 50 years ago, there have been 20 million deaths due to tobacco. Almost half the deaths from 12 different types of cancer combined – including lung, voice box, throat, esophagus, and bladder cancers – are attributable to cigarette smoking alone. In addition to cancer, smoking greatly increases the risk of debilitating long-term lung diseases like emphysema and chronic bronchitis. It also raises the risk for heart...
Source: American Cancer Society :: News and Features - November 16, 2016 Category: Cancer & Oncology Tags: Smoking/Tobacco Source Type: news

Cessation of Smoking and Alcohol Addiction Following Thalamic Hemorrhage
We describe a case of thalamic intracerebral hemorrhage leading to cessation of smoking. Case Report: A 53-year-old female presented to the emergency department with right-sided weakness and dysarthria. Initial systolic blood pressure was 220 mm Hg. Computed tomography scan showed a left thalamic hemorrhage with associated edema and hemorrhage extending into the left lateral and third ventricle. She recovered uneventfully and was discharged to inpatient rehabilitation and eventually transitioned home. Three months later in the clinic, she reported that following the stroke, she abruptly stopped smoking without any smoking...
Source: The Neurologist - November 1, 2016 Category: Neurology Tags: Case Report/Case Series Source Type: research

The effects of nicotine and nicotine abstinence on stress-induced cardiovascular reactivity: Do habitual and light/intermittent cigarette smokers differ?
The effects of 12 hr nicotine administration and abstinence on stress-induced cardiovascular reactivity were assessed within Light/Intermittent cigarette smokers and Habitual cigarette smokers. One hundred thirty-two male smokers (66 Habitual, 66 Light/Intermittent) were assigned to a Nicotine (21 mg) or Placebo patch condition. Cardiovascular reactivity was assessed during Baseline, a 6-min mental arithmetic task (Paced Auditory Serial Arithmetic Task) and a 5-min mirror-tracing task (Star Mirror Tracing Task). Within the Nicotine condition, Light/Intermittent smokers showed greater cardiac output (CO) increases, smaller ...
Source: Journal of Psychophysiology - August 8, 2016 Category: Psychiatry & Psychology Source Type: research

A Decade of e-Cigarettes: Limited Research & Unresolved Safety Concerns.
A Decade of e-Cigarettes: Limited Research & Unresolved Safety Concerns. Toxicology. 2016 Jul 28; Authors: Kaisar MA, Prasad S, Liles T, Cucullo L Abstract It is well known that tobacco consumption is a leading cause of preventable deaths worldwide and has been linked to major diseases ranging from cancer to chronic obstructive pulmonary disease, atherosclerosis, stroke and a host of neurological/neurodegenerative disorders. In the past decade a number of alternative vaping products have hit the market, rapidly gaining consumers especially among the younger population. Electronic nicotine delivery...
Source: Toxicology - July 27, 2016 Category: Toxicology Authors: Kaisar MA, Prasad S, Liles T, Cucullo L Tags: Toxicology Source Type: research

E-cigarettes: Good news, bad news
Follow me at @JohnRossMD Americans are confused about electronic cigarettes. A recent poll showed that the public was about evenly split between those who thought that electronic cigarettes, or e-cigarettes, were less harmful than conventional cigarettes, and those who believed that e-cigarettes were as bad as or worse than regular cigarettes. Unfortunately, there is no long-term safety data about e-cigarettes. What information we do have suggests that e-cigarettes have a complex mix of potential harms and benefits. E-cigarettes: Less deadly than regular cigarettes First, the good news: e-cigarettes are almost certainly le...
Source: New Harvard Health Information - July 25, 2016 Category: Consumer Health News Authors: John Ross, MD, FIDSA Tags: Behavioral Health Cancer Lung disease Prevention Smoking cessation Source Type: news