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Drug: Nicotine
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Total 216 results found since Jan 2013.
Association between electronic nicotine delivery systems use and risk of stroke: a meta-analysis of 1,024,401 participants
CONCLUSIONS: The ENDS usage appears to be associated with a higher risk of stroke compared to non-use, whereas there was no association between former ENDS use and the risk of stroke.PMID:37732043 | PMC:PMC10507757 | DOI:10.5114/aoms/171473
Source: Archives of Medical Science - September 21, 2023 Category: Biomedical Science Authors: Kamal Awad Maged Mohammed Seth S Martin Maciej Banach Source Type: research
7 Ways to Bring a Dead Friendship Back to Life
It might sound obvious, in the midst of a loneliness crisis, that having friends matters. But many of us “underestimate the very real impact our friendships can have on our life,” says Marisa Franco, a psychologist and author of Platonic: How The Science of Attachment Can Help You Make—and Keep—Friends. “Connection is the most important factor predicting our health, both physical and mental.”
A growing body of research supports that point: Healthy, stable friendships can protect against depression and anxiety, increase life satisfaction, extend longevity, and improve health metrics li...
Source: TIME: Health - August 4, 2023 Category: Consumer Health News Authors: Angela Haupt Tags: Uncategorized healthscienceclimate Source Type: news
Estimating the Cost of Delivering Tobacco Cessation Intervention Package at Non-Communicable Disease Clinics in Two Districts of North India
CONCLUSION: The development costs of the intervention package accounted for the majority proportion of the total cost. Of the total unit cost of implementation, the telephonic follow-up, human resources, and capital resources were the major contributory components.IMPLICATIONS: The current study aims to fill gaps by estimating the unit-level health systems cost of a culturally sensitive, disease-specific, and patient-centric tobacco cessation intervention package delivered at the outpatient settings of NCD clinics at the secondary level hospital, which represents a major link in the health care system of India. Findings fr...
Source: Cancer Control - July 4, 2023 Category: Cancer & Oncology Authors: Garima Bhatt Sonu Goel Tanvi Kira Sandeep Grover Bikash Medhi Gurmandeep Singh Sandeep Singh Gill Source Type: research
Regulation of endothelial function by cigarette smoke and next-generation tobacco and nicotine products
Pflugers Arch. 2023 Jun 7. doi: 10.1007/s00424-023-02824-w. Online ahead of print.ABSTRACTCigarette smoking is the most important avoidable cardiovascular risk factor. It causes endothelial dysfunction and atherosclerosis and increases the risk of its severe clinical complications like coronary artery disease, myocardial infarction, stroke, and peripheral artery disease. Several next-generation tobacco and nicotine products have been developed to decrease some of the deleterious effects of regular tobacco smoking. This review article summarizes recent findings about the impact of cigarette smoking and next-generation tobac...
Source: Atherosclerosis - June 7, 2023 Category: Cardiology Authors: Justus Klein Patrick Diaba-Nuhoho Sindy Giebe Coy Brunssen Henning Morawietz Source Type: research
Nicotine Treatment Ameliorates Blood-Brain Barrier Damage After Acute Ischemic Stroke by Regulating Endothelial Scaffolding Protein Pdlim5
AbstractAnalysis of a National Institutes of Health (NIH) trial shows that cigarette smoking protected tissue plasminogen activator (tPA)-treated patients from hemorrhage transformation (HT); however, the underlying mechanism is not clear. Damage to the integrity of the blood-brain barrier (BBB) is the pathological basis of HT. Here, we investigated the molecular events of BBB damage after acute ischemic stroke (AIS) usingin vitro oxygen-glucose deprivation (OGD) andin vivo mice middle cerebral artery occlusion (MCAO) models. Our results showed that the permeability of bEND.3 monolayer endothelial cells was significantly i...
Source: Translational Stroke Research - May 26, 2023 Category: Neurology Source Type: research
U.S. Adult Smoking Rate Hits New All-Time Low
NEW YORK — U.S. cigarette smoking dropped to another all-time low last year, with 1 in 9 adults saying they were current smokers, according to government survey data released Thursday. Meanwhile, electronic cigarette use rose, to about 1 in 17 adults.
The preliminary findings from the Centers for Disease Control and Prevention are based on survey responses from more than 27,000 adults.
Cigarette smoking is a risk factor for lung cancer, heart disease, and stroke, and it’s long been considered the leading cause of preventable death.
In the mid-1960s, 42% of U.S. adults were smokers. The rate has been gradually d...
Source: TIME: Health - April 27, 2023 Category: Consumer Health News Authors: Mike Stobbe/AP Tags: Uncategorized Addiction healthscienceclimate wire Source Type: news
Straight from the heart: Mysterious lipids may predict cardiac problems better than cholesterol
Stephanie Blendermann, 65, had good reason to worry about heart disease. Three of her sisters died in their 40s or early 50s from heart attacks, and her father needed surgery to bypass clogged arteries. She also suffered from an autoimmune disorder that results in chronic inflammation and boosts the odds of developing cardiovascular illnesses. “I have an interesting medical chart,” says Blendermann, a real estate agent in Prior Lake, Minnesota.
Yet Blendermann’s routine lab results weren’t alarming. At checkups, her low-density lipoprotein (LDL), or “bad,” cholesterol hovered around the 100 milligrams-per-...
Source: Science of Aging Knowledge Environment - March 16, 2023 Category: Geriatrics Source Type: research
Nicotine suppresses central post-stroke pain via facilitation of descending noradrenergic neuron through activation of orexinergic neuron
In this study, we evaluated whether nicotine could suppress BCAO-induced mechanical allodynia through the activation of orexinergic neurons. Mice were subjected to BCAO for 30 min. Mechanical hypersensitivity was assessed by the von Frey test. BCAO mice showed hypersensitivity to mechanical stimuli three days after BCAO surgery. The intracerebroventricular injection of nicotine suppressed BCAO-induced mechanical hypersensitivity in a dose-dependent manner. These effects were inhibited by α7 or α4β2-nicotinic receptor antagonists. After nicotine injection, the level of c-fos, a neuronal activity marker, increased in the ...
Source: European Journal of Pharmacology - January 27, 2023 Category: Drugs & Pharmacology Authors: Kazuo Nakamoto Wataru Matsuura Shogo Tokuyama Source Type: research
9 Ways to Squeeze in More Steps Every Day
Every day for the past decade, I’ve tried to dethrone the family walking champ: my 67-year-old dad. Despite my youthful advantage—he has more than 30 years on me, as he’s quick to point out—I haven’t logged more steps than him once. I find this to be both mortifying and a point of vicarious pride; his fitness is remarkable. It’s also excellent motivation to find creative ways to finally out-walk him.
My dad and I compete using our favorite pedometer app, which displays each day’s steps in a bar graph. (While we both wear Apple Watches, we like the app best for logging the entire da...
Source: TIME: Health - January 12, 2023 Category: Consumer Health News Authors: Angela Haupt Tags: Uncategorized Exercise & Fitness healthscienceclimate Source Type: news
Pathogenesis of (smoking-related) non-communicable diseases —Evidence for a common underlying pathophysiological pattern
Non-communicable diseases, like diabetes, cardiovascular diseases, cancer, stroke, chronic obstructive pulmonary disease, osteoporosis, arthritis, Alzheimer’s disease and other more are a leading cause of death in almost all countries. Lifestyle factors, especially poor diet and tobacco consumption, are considered to be the most important influencing factors in the development of these diseases. The Western diet has been shown to cause a significant distortion of normal physiology, characterized by dysregulation of the sympathetic nervous system, renin-angiotensin aldosterone system, and immune system, as well as disrupt...
Source: Frontiers in Physiology - December 15, 2022 Category: Physiology Source Type: research
