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Total 175 results found since Jan 2013.

Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017
Publication date: 10–16 November 2018Source: The Lancet, Volume 392, Issue 10159Author(s): Gregory A Roth, Degu Abate, Kalkidan Hassen Abate, Solomon M Abay, Cristiana Abbafati, Nooshin Abbasi, Hedayat Abbastabar, Foad Abd-Allah, Jemal Abdela, Ahmed Abdelalim, Ibrahim Abdollahpour, Rizwan Suliankatchi Abdulkader, Haftom Temesgen Abebe, Molla Abebe, Zegeye Abebe, Ayenew Negesse Abejie, Semaw F Abera, Olifan Zewdie Abil, Haftom Niguse Abraha, Aklilu Roba AbrhamSummaryBackgroundGlobal development goals increasingly rely on country-specific estimates for benchmarking a nation's progress. To meet this need, the Global Burden ...
Source: The Lancet - November 11, 2018 Category: General Medicine Source Type: research

Effects of introducing a fee for “bed blockers” on adverse events among patients hospitalized for chronic obstructive pulmonary disease, heart failure, hip fracture and stroke
Conclusion: Overall, there is no strong evidence to suggest that the Norwegian healthcare Coordination Reform is functioning in a manner that exacerbates risk for readmissions or death among the patients considered in this study. Even so, patients with heart failure appear somewhat vulnerable.   Published on 2018-10-23 00:00:00
Source: International Journal of Integrated Care - October 23, 2018 Category: Nursing Source Type: research

The Integration of Doppler Ultrasound With Two-Dimensional Echocardiography and the Noninvasive Cardiac Hemodynamic Revolution of the 1980s
In the 1970s, as cardiac imaging matured from M-mode to two-dimensional echocardiography, investigators in Norway showed that continuous-wave Doppler ultrasonography could be used to accurately measure the mean gradient and pressure half-time for stenotic mitral valves. In the 1980s, continuous-wave Doppler was validated for measurement of the pressure gradient across stenotic aortic valves, and pulsed-wave Doppler combined with two-dimensional echocardiographic imaging was validated for noninvasive measurement of stroke volume and cardiac output.
Source: Journal of the American Society of Echocardiography - October 16, 2018 Category: Cardiology Authors: Fletcher A. Miller Source Type: research

Veldig tidlig mobilisering ved akutt hjerneslag.
Abstract BACKGROUND: Since the first stroke units were established in the 1990s, early mobilisation has formed a key part of the acute treatment. In the context of an updating of national clinical guidelines for stroke, the Norwegian Directorate of Health commissioned the Institute of Public Health to prepare a systematic review of the efficacy and safety of very early mobilisation (within 24 hours) after stroke, compared with current practice, which is early mobilisation (within 48 hours). MATERIAL AND METHOD: We have written a systematic review based on a previous review from the Cochrane Collaboration publ...
Source: Tidsskrift for den Norske Laegeforening - October 15, 2018 Category: General Medicine Authors: Fure B, Holte HH, Hov L, Vist GE, Kateraas LH, Indredavik B Tags: Tidsskr Nor Laegeforen Source Type: research

Covariables and types of abnormal left ventricular geometry in nonelderly ischemic stroke survivors: the Norwegian Stroke in the Young Study
Background: Abnormal left ventricular (LV) geometry types, like LV hypertrophy (LVH) and concentric remodelling, are independently associated with impaired prognosis in hypertension. Little is known about the prevalence and covariables of abnormal LV geometry types in younger ischemic stroke patients. Methods: We used clinical and echocardiographic data from 280 patients aged 15–60 years included in the Norwegian Stroke in the Young Study. LVH was defined as LV mass index greater than 46.7 g/m2.7 in women and greater than 49.2 g/m2.7 in men. Concentric remodelling was considered present if posterior wall thickne...
Source: Journal of Hypertension - September 1, 2018 Category: Cardiology Tags: ORIGINAL PAPERS: Organ damage Source Type: research

Risk factors for stroke and choice of oral anticoagulant in atrial fibrillation
ConclusionsThe uptake of DOACs was rapid and spurred an increase in new users of oral anticoagulants for atrial fibrillation from 2010 to 2015 in Norway. The mean CHA2DS2-VASc score did not change substantially during this period. Vascular disease, heart failure, and diabetes were associated with initiation of warfarin, and previous stroke, age 65 –74 and female sex with initiation of DOACs.
Source: European Journal of Clinical Pharmacology - August 16, 2018 Category: Drugs & Pharmacology Source Type: research

Serum content of saturated fatty acids and the prevalence of atrial fibrillation - A norwegian cross-sectional study
Aim: Atrial fibrillation [AF] is a common cardiac arrhythmia with serious clinical consequences including a 5-fold higher risk of ischemic stroke. Serum content of saturated fatty acids (SFA) consisting of palmitic (C16:0) and stearic (C18:0) acid may be associated with the prevalence of AF.
Source: Atherosclerosis - August 1, 2018 Category: Cardiology Authors: P. Dinesen, S. Tveit, A. Kalstad, P. Myhre, K. Laake, S. Solheim, H. Arnesen, E.B. Schmidt, S. Lundbye-Christensen, I. Seljeflot Source Type: research

Differences in and Determinants of Prehospital Delay Times among Stroke Patients —1994 Versus 2012
This study investigates how prehospital delay among Norwegian stroke patients has changed over the last 2 decades.
Source: Journal of Stroke and Cerebrovascular Diseases - May 11, 2018 Category: Neurology Authors: Angela Susan Labberton, Kashif Waqar Faiz, Ole Morten R ønning, Bente Thommessen, Mathias Barra Source Type: research

Distribution of risk factors for cardiovascular disease and the estimated 10-year risk of acute myocardial infarction or cerebral stroke in Sami and non-Sami populations: The SAMINOR 2 Clinical Survey.
CONCLUSIONS: There were no differences in 10-year risk of AMI or CS between the Sami and non-Sami populations in 10 selected municipalities in Northern Norway. PMID: 29806547 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Public Health - May 1, 2018 Category: International Medicine & Public Health Authors: Siri SRA, Braaten T, Jacobsen BK, Melhus M, Eliassen BM Tags: Scand J Public Health Source Type: research

2.1-O8Distribution of risk factors for cardiovascular disease and 10-year risk of acute myocardial infarction and cerebral stroke in Sami and non-Sami populations in Norway. The SAMINOR 2 Clinical Survey.
Objective:
Source: The European Journal of Public Health - April 17, 2018 Category: General Medicine Source Type: research

Ibrutinib, lenalidomide, and rituximab in relapsed or refractory mantle cell lymphoma (PHILEMON): a multicentre, open-label, single-arm, phase 2 trial
Publication date: Available online 29 January 2018 Source:The Lancet Haematology Author(s): Mats Jerkeman, Christian Winther Eskelund, Martin Hutchings, Riikka Räty, Karin Fahl Wader, Anna Laurell, Helle Toldbod, Lone Bredo Pedersen, Carsten Utoft Niemann, Christina Dahl, Hanne Kuitunen, Christian H Geisler, Kirsten Grønbæk, Arne Kolstad Background Regimens based on ibrutinib alone and lenalidomide and rituximab in combination show high activity in patients with relapsed or refractory mantle cell lymphoma. We hypothesised that the combination of all three drugs would improve efficacy compared with previously published ...
Source: The Lancet Haematology - January 30, 2018 Category: Hematology Source Type: research

The PAr index, an indicator reflecting altered vitamin B-6 homeostasis, is associated with long-term risk of stroke in the general population: the Hordaland Health Study (HUSK)
ConclusionsHigher plasma PAr was independently associated with increased risk of incident stroke in all participants and across all subgroups stratified by conventional risk predictors. Our novel findings point to and expand the range of inflammation and immune activation processes that may be relevant for the pathogenesis and prevention of stroke. This trial was registered at clinicaltrials.gov as NCT03013725.
Source: American Journal of Clinical Nutrition - January 26, 2018 Category: Nutrition Source Type: research

Validation of intracranial hemorrhage in the Norwegian Patient  Registry
ConclusionCoding of ICH discharge diagnoses in the NPR is of high quality, showing that data from this registry can safely be used for medical research. Administrative and clinical health registries are established to monitor and manage healthcare services. Data from these registries can be used in epidemiological studies as they are easily obtained, include high number of patients, and provide both high external validity and statistical power. However, in order to be useful in research, health registries need to have accurate diagnoses and sufficient coverage in the population they serve. We validated coding of intracran...
Source: Brain and Behavior - January 23, 2018 Category: Neurology Authors: Lise R. Øie, Mattis A. Madsbu, Charalampis Giannadakis, Anders Vorhaug, Heidi Jensberg, Øyvind Salvesen, Sasha Gulati Tags: ORIGINAL RESEARCH Source Type: research

Prevalence and covariates of uncontrolled hypertension in ischemic stroke survivors: the Norwegian stroke in the young study.
CONCLUSION: Uncontrolled hypertension was highly prevalent in ischemic stroke survivors <60 years and associated with co-presence of obesity and functional and structural arterial damage. Our results highlight the unmet potential and challenge of optimization of hypertension diagnosis and management in order to prevent recurrent vascular events in ischemic stroke survivors. PMID: 29334265 [PubMed - as supplied by publisher]
Source: Blood Pressure - January 16, 2018 Category: Hematology Tags: Blood Press Source Type: research