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Total 370 results found since Jan 2013.

Determinants of extended door-to-needle time in acute ischemic stroke and its influence on in-hospital mortality: results of a nationwide Dutch clinical audit
Intravenous thrombolysis (IVT) plays a prominent role in the treatment of acute ischemic stroke (AIS). The sooner IVT is administered, the higher the odds of a good outcome. Therefore, registering the in-hospi...
Source: BMC Neurology - November 4, 2019 Category: Neurology Authors: Laurien S. Kuhrij, Perla J. Marang-van de Mheen, Renske M. van den Berg-Vos, Frank-Erik de Leeuw and Paul J. Nederkoorn Tags: Research article Source Type: research

2019 Cochrane-REWARD Prize winners announced
We are pleased to announce the winners – one first place and two runners-up – of this year’s Cochrane-REWARD Prize. The Cochrane-REWARD Prize recognizes successful local or pilot initiatives that have potential to reduce research waste globally if scaled up. Cochrane has funded the prize annually since it began in 2017.The prize ceremony took place on Wednesday 9 October at the International Clinical Trials Methodology Conference in Brighton, UK. Dr Joan Marsh, Deputy Editor of The Lancet Psychiatry and member of the prize committee, was there to hand out the prizes. During the conference, each recipient also had the...
Source: Cochrane News and Events - October 18, 2019 Category: Information Technology Authors: Lydia Parsonson Source Type: news

Total endovascular repair of the aortic arch: initial experience in the Netherlands
ConclusionsTotal endovascular aortic arch repair using the Relay Branch device is technically feasible and effective in excluding aortic arch pathology. The observed stroke rate in the initial experience, however, was considerable. Although appealing, this new lesser-invasive technique should be carefully introduced, and its progress thoroughly evaluated.
Source: The Annals of Thoracic Surgery - October 5, 2019 Category: Cardiovascular & Thoracic Surgery Source Type: research

Total endovascular repair of the aortic arch: initial experience in the Netherlands.
CONCLUSIONS: Total endovascular aortic arch repair using the Relay Branch device is technically feasible and effective in excluding aortic arch pathology. The observed stroke rate in the initial experience, however, was considerable. Although appealing, this new lesser-invasive technique should be carefully introduced, and its progress thoroughly evaluated. PMID: 31593657 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - October 4, 2019 Category: Cardiovascular & Thoracic Surgery Authors: van der Weijde E, Heijmen RH, van Schaik PM, Hazenberg CEVB, van Herwaarden JA Tags: Ann Thorac Surg Source Type: research

Safety and efficacy of a self-expanding versus a balloon-expandable bioprosthesis for transcatheter aortic valve replacement in patients with symptomatic severe aortic stenosis: a randomised non-inferiority trial
Publication date: Available online 27 September 2019Source: The LancetAuthor(s): Jonas Lanz, Won-Keun Kim, Thomas Walther, Christof Burgdorf, Helge Möllmann, Axel Linke, Simon Redwood, Christian Thilo, Michael Hilker, Michael Joner, Holger Thiele, Lars Conzelmann, Lenard Conradi, Sebastian Kerber, Gerhard Schymik, Bernard Prendergast, Oliver Husser, Stefan Stortecky, Dik Heg, Peter JüniSummaryBackgroundTranscatheter aortic valve replacement (TAVR) is the preferred treatment option for older patients with symptomatic severe aortic stenosis. Differences in the properties of available TAVR systems can affect clinical outcom...
Source: The Lancet - September 28, 2019 Category: General Medicine Source Type: research

Systematic review of subjective memory measures to inform assessing memory limitations after stroke and stroke-related aphasia.
Conclusions: This literature domain currently provides an unclear picture as to how memory limitations affect participation in stroke and stroke-related aphasia. IMPLICATIONS FOR REHABILITATION A broad range of subjective memory measures have been used to determine stroke survivors' perceptions of their everyday memory issues. Because of psychometric weaknesses such as inadequate reliability and cross-cultural validity among subjective memory measures, there remains a need to carefully review a given measure's properties to determine if it is appropriate for use with a given stroke survivor. Stroke survivors with aphasia h...
Source: Disability and Rehabilitation - September 26, 2019 Category: Rehabilitation Authors: Salis C, Murray L, Vonk JMJ Tags: Disabil Rehabil Source Type: research

Balloon Guide Catheter in Endovascular Treatment for Acute Ischemic Stroke: Results from the MR CLEAN Registry
ConclusionsIn clinical practice, use of a BGC was associated with higher reperfusion grade and early improvement of neurologic deficits, but had no positive effect on long-term functional outcome.
Source: Journal of Vascular and Interventional Radiology - September 19, 2019 Category: Radiology Source Type: research

Design and rationale of ischaemia-driven complete revascularisation versus usual care in patients with non-ST-elevation myocardial infarction and multivessel coronary disease: the South Limburg Myocardial Infarction (SLIM) trial.
CONCLUSION: The SLIM trial aims to provide evidence whether FFR-guided complete revascularisation by PCI is superior to usual care with respect to clinical outcomes (major adverse cardiovascular events) in non-STEMI patients with MVD. PMID: 31531823 [PubMed - as supplied by publisher]
Source: Netherlands Heart Journal - September 16, 2019 Category: Cardiology Authors: Pustjens TFS, Streukens B, Vainer J, Gho B, Ruiters AW, Stein M, Ilhan M, Veenstra L, Theunissen R, Bekkers SCAM, Van't Hof AWJ, Rasoul S Tags: Neth Heart J Source Type: research

Effect of sildenafil on maternal hemodynamics in pregnancies complicated by severe early-onset fetal growth restriction: planned subgroup analysis from a multicenter randomized placebo-controlled double-blind trial.
CONCLUSIONS: Sildenafil in a dose of 25 mg three times daily increases HR, reduces BP and reduces arterial stiffness in pregnancies complicated by FGR. These changes are modest, consistent with the anticipated vasodilatory effect and their clinical impact on the mother and baby, in both the short- and long-term, remains uncertain. This article is protected by copyright. All rights reserved. PMID: 31432556 [PubMed - as supplied by publisher]
Source: The Ultrasound Review of Obstetrics and Gynecology - August 19, 2019 Category: Radiology Authors: Khalil A, Sharp A, Cornforth C, Jackson R, Mousa H, Stock S, Harrold J, Turner MA, Kenny LC, Baker PN, Johnstone ED, von Dadelszen P, Magee L, Papageorghiou AT, Alfirevic Z Tags: Ultrasound Obstet Gynecol Source Type: research

Association Between Primary Care Practitioner Empathy and Risk of Cardiovascular Events and All-Cause Mortality Among Patients With Type 2 Diabetes: A Population-Based Prospective Cohort Study.
CONCLUSIONS: Positive patient experiences of practitioner empathy in the year after diagnosis of type 2 diabetes may be associated with beneficial long-term clinical outcomes. Further work is needed to understand which aspects of patient perceptions of empathy might influence health outcomes and how to incorporate this understanding into the education and training of practitioners. PMID: 31285208 [PubMed - in process]
Source: Annals of Family Medicine - June 30, 2019 Category: Primary Care Authors: Dambha-Miller H, Feldman AL, Kinmonth AL, Griffin SJ Tags: Ann Fam Med Source Type: research

Blunt cerebrovascular injury: incidence and long-term follow-up
ConclusionsImproved CTA diagnostic modalities have increased BCVI incidence. Furthermore, BCVI patients reported significant functional impairment at long-term follow-up. Antiplatelet therapy showed a significant effect on in-hospital stroke rate reduction.
Source: European Journal of Trauma and Emergency Surgery - June 12, 2019 Category: Emergency Medicine Source Type: research

Left atrial appendage closure in atrial fibrillation patients with prior major bleeding or ineligible for oral anticoagulation.
CONCLUSIONS: Percutaneous LAAC may provide an alternative strategy to long-term OAC therapy in AF patients with a high bleeding risk. During follow-up, both ischaemic stroke and recurrent bleeding rates were lower than expected based on the CHA2DS2-VASc and HAS-BLED scores respectively. PMID: 31187455 [PubMed - as supplied by publisher]
Source: Netherlands Heart Journal - June 10, 2019 Category: Cardiology Authors: Wintgens LIS, Vorselaars VMM, Klaver MN, Swaans MJ, Alipour A, Rensing BJWM, Post MC, Boersma LVA Tags: Neth Heart J Source Type: research

Young Stroke Survivors Face Increased Long-Term Death Risk Young Stroke Survivors Face Increased Long-Term Death Risk
A national Dutch study in more than 15,000 adults younger than 50 who survived at least 30 days following a first stroke suggests higher mortality risks over time for these patients.Medscape Medical News
Source: Medscape Cardiology Headlines - May 29, 2019 Category: Cardiology Tags: Neurology & Neurosurgery News Source Type: news

Association Between Stroke and Mortality in Young Adults
This cohort study uses Dutch registry and population data to estimate associations between incident stroke occurring between ages 18 and 49 years and short- and long-term all-cause mortality stratified by age, sex, and stroke subtype.
Source: JAMA - Journal of the American Medical Association - May 23, 2019 Category: General Medicine Source Type: research

Development and validity of an innovative test to assess guideline-consistent clinical reasoning by physical therapists in stroke rehabilitation.
CONCLUSION: The script concordance test has good construct validity. Greater self-reported guideline knowledge, successful completion of the post-bachelor Dutch Neurorehabilitation course, as well as systematic participation in professional development activities facilitate important factors that enhance specialization. The script concordance test is a valid feedback tool for physical therapists to support professional development in the domain of stroke rehabilitation. PMID: 31099400 [PubMed - as supplied by publisher]
Source: Journal of Rehabilitation Medicine - May 19, 2019 Category: Rehabilitation Tags: J Rehabil Med Source Type: research