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Total 404 results found since Jan 2013.

Ketamine Therapy for Treatment-resistant Depression in a Patient with Multiple Sclerosis: A Case Report
Conclusion—Ketamine may be an alternative treatment for resistant depression and may have a special use in patients with multiple sclerosis. Introduction Depression is a frequent finding in patients with multiple sclerosis (MS), with the lifetime prevalence rates for major depressive disorder (MDD) ranging from 36 to 54 percent, more than twice of that in the general population.[1] Even with advances in pharmacological options for treating depression, an estimated 33 to 66 percent of patients with MDD in the general population do not respond to the first antidepressant, and a reported 15 to 33 percent of patients do not ...
Source: Innovations in Clinical Neuroscience - February 1, 2017 Category: Neuroscience Authors: ICN Online Editor Tags: Case Report Current Issue Depression Multiple Sclerosis Neurology Psychiatry Psychopharmacology Electroconvulsive therapy Ketamine major depressive disorder treatment-resistant depression Source Type: research

The Association of Lesion Location and Sleep Related Breathing Disorder in Patients with Acute Ischemic Stroke
ConclusionWe found no association of lesion location and SRBD in stroke patients, whereas established risk factors for SRBD, known from general population, were significantly associated with SRBD. Given the high prevalence of SRBD in stroke patients, these findings suggest that cerebral ischemia facilitates the occurrence of SRBD in patients with pre-existing risk factors rather than causing it by damaging specific central nervous system structures. Our findings can be used to identify stroke patients who might benefit from polygraphy screening.
Source: PLoS One - January 29, 2017 Category: Biomedical Science Authors: Anna Lena Fisse Source Type: research

Myocardial fibrosis detected with Gadolinium Delayed Enhancement in Cardiac Magnetic Resonance Imaging and Ventriculoarterial Coupling alterations in patients with Acute Myocarditis.
CONCLUSION: In acute myocarditis patients, DGE is related to neither EF nor VAC; however, EF significantly affects the VAC status. Further studies are needed to investigate the potential quantitative, rather than qualitative, relationships between these variables. PMID: 28081949 [PubMed - as supplied by publisher]
Source: Hellenic Journal of Cardiology - January 15, 2017 Category: Cardiology Tags: Hellenic J Cardiol Source Type: research

Cerebral Microbleeds on MRI in Patients with Obstructive Sleep Apnea
Conclusions:Moderate-to-severe OSA can be one of the independent predictors of CMBs which are considered a surrogate marker of overt stroke.Citation:Koo DL, Kim JY, Lim JS, Kwon HM, Nam H. Cerebral microbleeds on MRI in patients with obstructive sleep apnea.J Clin Sleep Med. 2017;13(1):65–72.
Source: Journal of Clinical Sleep Medicine : JCSM - January 14, 2017 Category: Sleep Medicine Source Type: research

Energy efficiency and pulmonary artery flow after balloon pulmonary angioplasty for inoperable, chronic thromboembolic pulmonary hypertension: Analysis by phase-contrast MRI
Conclusion Analysis of PA energetics using phase-contrast MRI demonstrates that BPA improves energy loss in CTEPH. In addition, BPA responses can be predicted by PA energy status pre-treatment.
Source: European Journal of Radiology - December 16, 2016 Category: Radiology Source Type: research

Posterior Reversible Encephalopathy Syndrome with Extensive Deep White Matter Lesions Including the Temporal Pole.
We report the case of a 55-year-old man with atypical PRES, who had malignant hypertension and renal dysfunction. Magnetic resonance imaging of the brain revealed extensive vasogenic edema in the deep white matter including the temporal pole, as well as in the brainstem and cerebellum. Antihypertensive therapy and hemodialysis contributed to both clinical and radiological improvement. Involvement of the deep white matter including the temporal pole, which is rarely affected in an ischemic stroke, should be recognized as a potential sign of PRES. PMID: 27904123 [PubMed - in process]
Source: Internal Medicine - December 3, 2016 Category: Internal Medicine Tags: Intern Med Source Type: research

Contrast ‐induced encephalopathy following cardiac catheterization
ConclusionsCIE is an important clinical entity to consider in the differential diagnosis of stroke following cardiac catheterization. Given that prognosis is excellent with supportive management only, physicians should be aware of it, and consider it prior to initiating thrombolysis. © 2016 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - November 28, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Roberto Spina, Neil Simon, Romesh Markus, David WM Muller, Krishna Kathir Tags: Coronary Artery Disease Source Type: research

Interaction of incidental microbleeds and prior use of antithrombotics with early hemorrhagic transformation: Causative or protective ?
Conclusion: Presence of incidental CMBs was not associated with increased risk for early HT of an ischemic stroke. Interestingly, the prior intake of antiplatelets was found to be protective against HT of ischemic stroke.
Source: Annals of Indian Academy of Neurology - November 21, 2016 Category: Neurology Authors: Konark Malhotra Monica Khunger Bichun Ouyang David S Liebeskind Yousef M Mohammad Source Type: research

A Case of Hypertensive Encephalopathy with Enlarged Optic Nerve Sheath Measured by Transorbital Sonography
This case report describes our experience in using transorbital sonography to evaluate pathological changes in the central nervous system in hypertensive encephalopathy. A 49-year-old man with nausea, headache, and mild confusion was diagnosed with hypertensive encephalopathy by brain magnetic resonance imaging (MRI), which revealed vasogenic edema in the bilateral thalamus and the brain stem. Lumbar puncture showed no severe intracranial hypertension. Transorbital sonography showed an increase in the optic nerve sheath diameter (ONSD).
Source: Journal of Stroke and Cerebrovascular Diseases - November 8, 2016 Category: Neurology Authors: Takaya Kitano, Tomohisa Nezu, Tomoya Mukai, Jyunichi Uemura, Yuko Wada, Yoshiki Yagita Tags: Case Studies Source Type: research

Response to treatment assessment in patients with PAH by MRI based computational modelling
Conclusion: The non-invasive proposed metrics have the potential to assess the response to PAH therapy, reducing the RHC interventions at follow-up.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Lungu, A., Hose, R., Capener, D., Kiely, D., Wild, J., Swift, A. Tags: 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases Source Type: research

Age is independently associated with pulmonary arterial compliance in health and in patients with pulmonary vascular disease
Discussion: Advancing age is independently associated with pulmonary arterial compliance in health and disease. In contrast to younger patients, pulmonary arterial compliance does not increase in response to PAH therapy in older patients.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Swift, A., Lungu, A., Capener, D., Hammerton, C., Rothman, A., Lawrie, A., Elliot, C., Condliffe, R., Kiely, D., Wild, J. Tags: 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases Source Type: research

Cerebral venous thrombosis.
Abstract Cerebral venous thrombosis (CVT) has an incidence of 1.32/100,000/years in high-income countries, and higher in middle- and low-income countries. CVT is more frequent in infants and children young adults and females, especially during pregnancy/puerperium. CVT are now being diagnosed with increasing frequency because of the increased awareness and higher use of magnetic resonance imaging (MR) for investigating patients with acute and subacute headaches and new onset seizures. CVT rarely present as a stroke syndrome. Their most frequent presentations are isolated headache, intracranial hypertension syndrom...
Source: Presse Medicale - November 1, 2016 Category: Journals (General) Authors: Ferro JM, Canhão P, Aguiar de Sousa D Tags: Presse Med Source Type: research

Risk factors between intracranial-extracranial atherosclerosis and anterior-posterior circulation stroke in ischaemic stroke.
CONCLUSION: Risk factors are different between ICAS and ECAS, ACS and PCS, and ICAS/ECAS with ACS/PCS. Thus, targeted strategies are needed to consider these differences to prevent, treat and manage these diseases. PMID: 27796172 [PubMed - as supplied by publisher]
Source: Neurological Research - November 1, 2016 Category: Neurology Tags: Neurol Res Source Type: research

Pontine Warning Syndrome: A Chameleon of Ischemic Stroke
Conclusions: PWS is a diagnostic and management challenge for the clinician. Because of its low incidence, this syndrome has been underestimated and understudied. There is, currently, no standard treatment for this condition; however, it is paramount, during treatment, that hypotension/hypoperfusion be avoided, with the goal being asymptomatic normotension to permissive hypertension. The probable mechanism of disease is hypoperfusion due to basilar artery branch disease and perhaps cerebral vascular dysregulation in the affected area.
Source: The Neurologist - November 1, 2016 Category: Neurology Tags: Case Report/Case Series Source Type: research

Association Between Endogenous Testosterone and Cerebrovascular Disease in the ARIC Study (Atherosclerosis Risk in Communities) Clinical Sciences
Conclusions—After controlling for atherosclerotic risk factors, there was no association between endogenous testosterone and incident clinical stroke or ischemic brain changes in community-dwelling men.
Source: Stroke - October 23, 2016 Category: Neurology Authors: Srinath, R., Gottesman, R. F., Hill Golden, S., Carson, K. A., Dobs, A. Tags: Aging, Risk Factors, Ischemic Stroke Original Contributions Source Type: research