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Condition: Hypertension
Procedure: MRI Scan

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Total 404 results found since Jan 2013.

Association between Twenty-Four-Hour Ambulatory Blood Pressure Variability and Cerebral Small Vessel Disease Burden in Acute Ischemic Stroke
CONCLUSIONS: Higher BPV was significantly related to total cSVD burden in AIS patients. 24 h SBP SD and day mean SBP were independent risk factors for cSVD burden in AIS patients but not DBP or DBP variability.PMID:36304138 | PMC:PMC9596265 | DOI:10.1155/2022/3769577
Source: Behavioural Neurology - October 28, 2022 Category: Neurology Authors: Jun Shen Lu Yang Ziwei Xu Wenshi Wei Source Type: research

Cerebrovascular G < sub > i < /sub > Proteins Protect Against Brain Hypoperfusion and Collateral Failure in Cerebral Ischemia
We examined the importance of GiPCR signaling in cerebral blood flow (CBF) and its stability after sudden interruption using various in vivo high-resolution magnetic resonance imaging techniques. To this end, we induced a functional knockout of GiPCR signaling in the brain vasculature by injection of pertussis toxin (PTX). Our results show that PTX induced global brain hypoperfusion and microvascular collapse. When PTX-pretreated animals underwent transient unilateral occlusion of one common carotid artery, CBF was disrupted in the ipsilateral hemisphere resulting in the collapse of the cortically penetrating microvessels....
Source: Molecular Medicine - September 8, 2022 Category: Molecular Biology Authors: Salvador Castaneda-Vega Sandra Beer-Hammer Veronika Leiss Hanna Napieczy ńska Marta Vuozzo Andreas M Schmid Hang Zeng Yi He Ursula Kohlhofer Irene Gonzalez-Menendez Leticia Quintanilla-Martinez Johann-Martin Hempel Maik Gollasch Xin Yu Bernd J Pichler Be Source Type: research

Cerebrovascular Gi Proteins Protect Against Brain Hypoperfusion and Collateral Failure in Cerebral Ischemia
We examined the importance of GiPCR signaling in cerebral blood flow (CBF) and its stability after sudden interruption using variousin vivo high-resolution magnetic resonance imaging techniques. To this end, we induced a functional knockout of GiPCR signaling in the brain vasculature by injection of pertussis toxin (PTX). Our results show that PTX induced global brain hypoperfusion and microvascular collapse. When PTX-pretreated animals underwent transient unilateral occlusion of one common carotid artery, CBF was disrupted in the ipsilateral hemisphere resulting in the collapse of the cortically penetrating microvessels. ...
Source: Molecular Imaging and Biology - September 8, 2022 Category: Molecular Biology Source Type: research

54-Year-Old Woman With Altered Mental Status and Abdominal Pain
A 54-year-old woman was transferred to our medical center with altered mental status, abdominal pain, and hypotension. Her medical history included type 2 diabetes mellitus, hypertension, hyperlipidemia, active tobacco use, prior cholecystectomy, and a recent stroke. One month earlier, she presented to an outside facility with right-sided facial weakness and numbness. Brain magnetic resonance imaging (MRI) at that time revealed multiple small lacunar-type infarcts. Computed tomography (CT) angiography of the head and neck, 48-hour Holter monitoring, and transesophageal echocardiography did not reveal an embolic source.
Source: Mayo Clinic Proceedings - June 29, 2022 Category: Internal Medicine Authors: Caroline L. Matchett, Nikita Rafie, Jacob C. Jentzer Tags: Residents ’ Clinic Source Type: research

Blunted cardiovascular effects of beta-blockers in patients with cirrhosis: Relation to severity?
ConclusionWe found the effect of beta-blockade on cardiac index in patients with advanced cirrhosis to be less potent than in patients with early cirrhosis, indicating that underlying cirrhotic cardiomyopathy increases, and the cardiac compensatory reserve becomes more compromised, with disease progression. The differential effects of beta-blockade in the left atrium may be used to predict the effect of beta-blockers on portal pressure, but further studies are needed to investigate this possibility.
Source: PLoS One - June 28, 2022 Category: Biomedical Science Authors: Puria Nabilou Source Type: research

Silent brain infarction is associated with carotid siphon calcification in ischemic stroke patients
CONCLUSIONS: Patients with SBI at acute phase of ischemic stroke have more risk factors than mentioned previously. SBI associated with the intimal pattern of CSC which relate to the atherosclerosis process in symptomatic ischemic stroke patients.PMID:35644109 | DOI:10.1016/j.nicl.2022.103050
Source: Atherosclerosis - June 1, 2022 Category: Cardiology Authors: Jingjing Li Yuhua Fan Jian Zhang Shihui Xing Shujin Tang Xiaoshuang Li Chao Dang Jinsheng Zeng Source Type: research