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Condition: Hemorrhagic Stroke
Nutrition: Calcium

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Total 162 results found since Jan 2013.

Clevidipine: A Review of Its Use for Managing Blood Pressure in Perioperative and Intensive Care Settings
In conclusion, intravenous clevidipine is a valuable agent for the management of BP in perioperative and intensive care settings.
Source: Drugs - October 14, 2014 Category: Drugs & Pharmacology Source Type: research

Bedtime Hypertension Chronotherapy: Concepts and Patient Outcomes.
Abstract Recent findings indicate cardiovascular disease (CVD) risk is best predicted by asleep systolic blood pressure (SBP), and lowering it by scheduling ≥1 conventional long-acting hypertension medications, alone or in combination, at bedtime significantly lessens vascular-associated risks. Some 20 years ago, four controlled-onset extended-release drug-delivery systems incorporating a calcium channel blocker or β-blocker, with the treatment goal specifically being attenuation of morning rather than asleep BP, were conceived as one type of bedtime hypertension chronotherapy. However, the CONVINCE outcomes tr...
Source: Current Pharmaceutical Design - October 24, 2014 Category: Drugs & Pharmacology Authors: Smolensky MH, Hermida RC, Ayala DE, Portaluppi F Tags: Curr Pharm Des Source Type: research

Lower Serum Calcium Level Is Associated With Hemorrhagic Transformation After Thrombolysis Brief Reports
Conclusions— Lower admission serum calcium level is independently associated with HT after IVT, and this hypothesis needs larger confirmatory trials.
Source: Stroke - April 27, 2015 Category: Neurology Authors: Guo, Y., Yan, S., Zhang, S., Zhang, X., Chen, Q., Liu, K., Liebeskind, D. S., Lou, M. Tags: Thrombolysis Brief Reports Source Type: research

Therapeutic hypothermia for acute brain injuries
Therapeutic hypothermia, recently termed target temperature management (TTM), is the cornerstone of neuroprotective strategy. Dating to the pioneer works of Fay, nearly 75 years of basic and clinical evidence support its therapeutic value. Although hypothermia decreases the metabolic rate to restore the supply and demand of O2, it has other tissue-specific effects, such as decreasing excitotoxicity, limiting inflammation, preventing ATP depletion, reducing free radical production and also intracellular calcium overload to avoid apoptosis. Currently, mild hypothermia (33°C) has become a standard in post-resuscitative care...
Source: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine - June 5, 2015 Category: Emergency Medicine Authors: Max AndresenJose GazmuriArnaldo MarínTomas RegueiraMaximiliano Rovegno Source Type: research

Magnetic resonance susceptibility weighted imaging in neurosurgery: current applications and future perspectives.
Abstract Susceptibility weighted imaging (SWI) is a relatively new imaging technique. Its high sensitivity to hemorrhagic components and ability to depict microvasculature by means of susceptibility effects within the veins allow for the accurate detection, grading, and monitoring of brain tumors. This imaging modality can also detect changes in blood flow to monitor stroke recovery and reveal specific subtypes of vascular malformations. In addition, small punctate lesions can be demonstrated with SWI, suggesting diffuse axonal injury, and the location of these lesions can help predict neurological outcome in pati...
Source: Journal of Neurosurgery - July 24, 2015 Category: Neurosurgery Authors: Di Ieva A, Lam T, Alcaide-Leon P, Bharatha A, Montanera W, Cusimano MD Tags: J Neurosurg Source Type: research

Neuron-Specific Enolase, S100 Calcium-Binding Protein B, and Heat Shock Protein 70 Levels in Patients With Intracranial Hemorrhage
Abstract: The authors evaluated neuron-specific enolase (NSE), S100 calcium-binding protein B (S100B), and heat shock protein 70 (HSP 70) levels and their relationships with in-hospital mortality, Glasgow Coma Scale (GCS) scores, and National Institute of Health Stroke Scale (NIHSS) scores. In total, 35 patients older than 18 years were presented to our emergency department and were diagnosed with non-traumatic intracranial hemorrhage (ICH) and 32 healthy controls were included. Blood samples were drawn on days 0 and 5. S100 calcium-binding protein B and HSP levels were significantly higher in patients than in controls on ...
Source: Medicine - November 1, 2015 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

EP3, Prostaglandin E2 Receptor Subtype 3, Associated with Neuronal Apoptosis Following Intracerebral Hemorrhage.
Abstract EP3 is prostaglandin E2 receptor subtype 3 and mediates the activation of several signaling pathways, changing in cAMP levels, calcium mobilization, and activation of phospholipase C. Previous studies demonstrated a direct role for EP3 in various neurodegenerative disorders, such as stroke and Alzheimer disease. However, the distribution and function of EP3 in ICH diseases remain unknown. Here, we demonstrate that EP3 may be involved in neuronal apoptosis in the processes of intracerebral hemorrhage (ICH). From the results of Western blot and immunohistochemistry, we obtained a significant up-regulation o...
Source: Cellular and Molecular Neurobiology - December 30, 2015 Category: Cytology Authors: Ni H, Shen J, Song Y, Cao M, Liu X, Huang J, Zhang W, Xie L, Ning X, Ke K Tags: Cell Mol Neurobiol Source Type: research

Serum Calcium and Phosphate Levels and Short- and Long-Term Outcomes in Acute Intracerebral Hemorrhage Patients
We investigated whether admission serum calcium and phosphate levels are associated with short- and long-term outcomes in patients with acute intracerebral hemorrhage.
Source: Journal of Stroke and Cerebrovascular Diseases - January 29, 2016 Category: Neurology Authors: Shoujiang You, Qiao Han, Jiaping Xu, Chongke Zhong, Yu Zhang, Huihui Liu, Yanlin Zhang, Xinshun Xu, Chunfeng Liu, Yongjun Cao Source Type: research

Summary: International Kidney Cancer Symposium
Conclusions:  Ideal ischemia time is 20-25 minutes or less improves short and long term renal function.  >25 minutes carried 5 year risk of new onset stage 4 CKD No differences on GFR for cold vs. warm ischemia times Preoperative GFR and the percent of kidney preserved was a better predictor of post op GFR.  No ischemia preserves renal function better than warm. Longer cold ischemia times were equivalent to shorter warm ischemia times. Quality and quantity of the remaining kidney is associated with ultimate renal function. Robotics in RCC Surgery Gennady Bratslavsky, MD The...
Source: Kidney Cancer Association - December 15, 2011 Category: Urology & Nephrology Source Type: news

Reversible Cerebral Vasoconstriction Syndrome Presenting With Visual Field Defects
Abstract: A 45-year-old woman with a history of depression and anxiety, treated with selective serotonin reuptake inhibitors (SSRIs), experienced acute, recurrent, and severe bifrontal headaches. Over time, she developed a left homonymous hemianopia and mental status changes. MRA revealed segmental vasoconstriction of cerebral arteries in multiple vascular distributions. She was treated with a calcium-channel blocker and magnesium, and there was resolution of her symptoms and cerebrovascular changes. Her clinical course and neuroimaging findings were consistent with reversible cerebral vasoconstriction syndrome. Although r...
Source: Journal of Neuro-Ophthalmology - June 1, 2016 Category: Opthalmology Tags: Clinical Observation Source Type: research

Principles and Clinical Application of Dual-energy Computed Tomography in the Evaluation of Cerebrovascular Disease
Charlie Chia-Tsong Hsu, Gigi Nga Chi Kwan, Dalveer Singh, Jit Pratap, Trevor William WatkinsJournal of Clinical Imaging Science 2016 6(1):27-27Dual-energy computed tomography (DECT) simultaneously acquires images at two X-ray energy levels, at both high- and low-peak voltages (kVp). The material attenuation difference obtained from the two X-ray energies can be processed by software to analyze material decomposition and to create additional image datasets, namely, virtual noncontrast, virtual contrast also known as iodine overlay, and bone/calcium subtraction images. DECT has a vast array of clinical applications in imagin...
Source: Journal of Clinical Imaging Science - June 28, 2016 Category: Radiology Authors: Charlie Chia-Tsong HsuGigi Nga Chi KwanDalveer SinghJit PratapTrevor William Watkins Source Type: research

The Need for a Rational Approach to Vasoconstrictive Syndromes: Transcranial Doppler and Calcium Channel Blockade in Reversible Cerebral Vasoconstriction Syndrome
Conclusion: Though small, our cohort demonstrates potential utility of TCD to monitor RCVS, and relative superiority of extended-release verapamil over other calcium channel blockers, illustrating the need for larger randomized trials. Case Rep Neurol 2016;8:161 –171
Source: Case Reports in Neurology - July 29, 2016 Category: Neurology Source Type: research

E-043 Reversible Cerebral Vasoconstriction Syndrome: Non-invasive Imaging Findings and Angiographic Evaluation
We present indirect findings on non-invasive imaging, such as transient cerebral edema, convexal subarachnoid hemorrhage, intraparenchymal hemorrhage and cerebral. Direct signs of single or multivessel arterial vasoconstriction are seen on CTA, MRA and confirmed on DSA. Reversibility of the vasoconstriction is demonstrated after intra-arterial administration of calcium channel blocker. Conditions such as diffuse atherosclerotic arterial narrowing, vasculitis, posterior reversible encephalopathy, cerebral edema secondary to venous congestion and vasospasm secondary to aneurysmal subarachnoid hemorrhage were among the pathol...
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: de Macedo Rodrigues, K., Hito, R., Takhtani, D., Lozano, J., Wakhloo, A., Puri, A. Tags: Electronic poster abstracts Source Type: research

Pattern of antihypertensive therapy among diabetic hyperten- sive patients in zewditu memorial hospital, addis ababa.
CONCLUSION: The pattern of antihypertensive drug therapy in our patients was consistent with the current treatment guidelines. However, the majority of diabetic-hypertensive patients did not reach target blood pressure. PMID: 27476227 [PubMed - in process]
Source: Ethiopian Medical Journal - August 3, 2016 Category: African Health Tags: Ethiop Med J Source Type: research

Association Between Calcium Level and Hematoma Size and Expansion
Intracerebral hemorrhage (ICH) is a common and deadly type of stroke, with high rates of morbidity and mortality (40%-50% in most series). There are several well-described and validated risk factors and diseases that increase the risk of ICH, including race, hypertension, use of anticoagulants, amyloid angiopathy, renal insufficiency, thrombolytic therapy, and drug abuse. However, not all ICHs are associated with one of these risk factors. This suggests that there might be some other modifying factors involved.
Source: JAMA Neurology - September 6, 2016 Category: Neurology Source Type: research