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Predicting The Onset Of Diabetes-Related Complications After A Diabetes Diagnosis With Machine Learning Algorithms
The burden of Diabetes has been ranked as the eighth cause in the ranking of causes of disability-adjusted life years (DALYs) all over the world [1,2], accounting for 2.8% of total DALYs and with an increase of more than 148% in 2019 as compared with the data obtained in 1990 [2]. Diabetes is one of the most significant factors increasing the risk of mortality, morbidity, and disability worldwide, and its economic burden demands new ways to curb diabetes healthcare expenditure [3]. Furthermore, people with diabetes are at greater risk of additionally suffering from cardiovascular diseases, such as heart attack or stroke [4...
Source: Diabetes Research and Clinical Practice - September 15, 2023 Category: Endocrinology Authors: Toni Mora, David Roche, Beatriz Rodr íguez-Sánchez Source Type: research

Cardiorenal Outcomes with Finerenone in Asian Patients with Chronic Kidney Disease and Type 2 Diabetes: A FIDELIO-DKD post hoc Analysis
CONCLUSION: Finerenone produces similar cardiorenal benefits in Asian and non-Asian patients.PMID:37708857 | DOI:10.1159/000532102
Source: American Journal of Nephrology - September 14, 2023 Category: Urology & Nephrology Authors: Daisuke Koya Stefan D Anker Luis M Ruilope Peter Rossing ZhiHong Liu Byung Wan Lee Chien-Te Lee Charlie Scott Peter Kolkhof Robert Lawatscheck Lili Wang Amer Joseph Bertram Pitt FIDELIO-DKD Investigators Source Type: research

Mortality risk after the first occurrence of osteoporotic vertebral compression fractures in the general population: A nationwide cohort study
This study aimed to evaluate mortality risk after the first occurrence of OVCF in the general population using a nationwide dataset from the Korean National Health Insurance System. We identified 291,203 newly diagnosed patients with OVCF and 873,609 patients without OVCF at a ratio of 1:3 matched by sex and age between 2010 and 2012. We investigated the latent characteristics of patients’ demographic information and chronic comorbidities that could affect mortality when diagnosed with OVCF. By comparing the cohort data, the hazar d ratio for subsequent mortality in patients with OVCF was calculated and adjusted based on...
Source: PLoS One - September 14, 2023 Category: Biomedical Science Authors: Hee Jung Son Source Type: research

Cardiovascular disease and risk factors in adults with diabetes mellitus in Hungary: a population-based study
The objective of this study was to estimate the prevalence of CVD in individuals with DM and to investigate the association between potential risk factors and the presence of CVD among individuals with DM in a population-based sample.MethodsThe study was based on data from three waves of the European Health Interview Surveys (EHIS) conducted in Hungary in 2009, 2014, and 2019.ResultsThe prevalence of CVD among patients with DM decreased during the study period and that socioeconomic factors, cardiometabolic risk factors including high blood pressure and high cholesterol, and depression are major contributors to CVD burden ...
Source: Frontiers in Endocrinology - September 14, 2023 Category: Endocrinology Source Type: research

Predictors of failure of early neurological improvement in early time window following endovascular thrombectomy: a multi-center study
ConclusionDiabetes mellitus history, pre-stroke mRS, longer last known well-to-puncture time, lack of modified thrombolysis in cerebral infarction = 3, and the number of mechanical thrombectomy passes are the predictors of FENI. Future large-scale studies are required to validate these findings.
Source: Frontiers in Neurology - September 14, 2023 Category: Neurology Source Type: research

Differential Cardiovascular Outcomes of Each Antihypertensive Drug Class in Patients With Hypertension and Breast Cancer Undergoing Doxorubicin-Containing Chemotherapy
CONCLUSION: RAS inhibitors are preferred for the treating hypertension and improving CV outcomes in patients with hypertension and breast cancer undergoing DOX-containing chemotherapy, particularly in patients with comorbid diabetes. However, CCBs are equivalent to RAS inhibitors and are more favorable than BBs and TDs in terms of improving CV outcomes.PMID:37704380 | DOI:10.4048/jbc.2023.26.e34
Source: Journal of Breast Cancer - September 13, 2023 Category: Cancer & Oncology Authors: Hui-Jeong Hwang Sang-Ah Han Source Type: research

Linking biomarkers with healthy lifestyle outcomes after stroke: Supplementary Results of a 12-month Randomized Controlled Trial
Participation in a healthy lifestyle intervention such as the Diabetes Prevention Program Group Lifestyle Balance –adapted for stroke (GLB-CVA) may reduce stroke burden. Identifying biomarkers associated with lifestyle changes may enhance an individualized approach to stroke recovery. We investigated metabolic biomarkers related to cardiovascular and neurological function in individuals with stroke in the GLB -CVA study and healthy (non-stroke) individuals.
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - September 13, 2023 Category: Nutrition Authors: Chad Swank, Evan McShan, Teodoro Bottiglieri, Sandy Zurawski, Librada Callender, Monica Bennett, Randi Dubiel, Simon Driver Source Type: research