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Condition: Aortic Aneurysm

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Total 540 results found since Jan 2013.

Single-center mid-term experience with chimney-graft technique for the preservation of flow to the supra-aortic branches.
Conclusions The chimney-graft technique, despite a technically demanding strategy, is a useful tool as bailout procedure in our armamentarium for high-risk patients, unsuitable for open or hybrid repair. PMID: 29022854 [PubMed - as supplied by publisher]
Source: Vascular - January 1, 2017 Category: Surgery Authors: Shahverdyan R, Mylonas S, Gawenda M, Brunkwall J Tags: Vascular Source Type: research

Medtronic launches pivotal trial of Intrepid TMVR system
Medtronic (NYSE:MDT) said today it launched a pivotal trial of its Intrepid transcatheter mitral valve replacement system after winning FDA investigational device exemption for the device. The 1st patient in the trial was enrolled at Milwaukee’s Aurora St. Luke’s Medical Center, the Fridley, Minn.-based company said. The Apollo trial is slated to enroll up to 1,200 patients with severe, symptomatic mitral valve regurgitation into 2 cohorts with a primary endpoint of composite of all-cause mortality, all-stroke, reoperation or reintervention and cardiovascular hospitalization at 1 year. Secondary endpoints in t...
Source: Mass Device - October 23, 2017 Category: Medical Devices Authors: Fink Densford Tags: Cardiac Implants Cardiovascular Catheters Clinical Trials Replacement Heart Valves Medtronic Source Type: news

Long-term risk and predictors of cardiovascular death in stable coronary artery disease: the CORONOR study
Conclusion: In stable CAD patients widely treated by secondary prevention medications, the main causes of CVD are death from HF and sudden death. The risk of CVD can be predicted by simple baseline variables. New therapeutic strategies are needed for the high-risk patients.
Source: Coronary Artery Disease - November 2, 2017 Category: Cardiology Tags: Original Research Source Type: research

Heroin Use Could Be Also Associated with Ruptured Aortic Aneurysms
Source: Translational Stroke Research - December 15, 2017 Category: Neurology Source Type: research

Alpha-2-antiplasmin Arg407Lys polymorphism and cryptogenic ischemic cerebrovascular events: Association with neurological deficit
Conclusion The presence of 407Lys allele is associated with better prognosis in cryptogenic cerebrovascular events. Our findings suggest that the α2AP Arg407Lys polymorphism could be involved in the pathogenesis of cerebral ischemia and its outcomes.
Source: Polish Journal of Neurology and Neurosurgery - December 26, 2017 Category: Neurosurgery Source Type: research

Alpha-2-antiplasmin Arg407Lys polymorphism and cryptogenic ischemic cerebrovascular events: Association with neurological deficit.
CONCLUSION: The presence of 407Lys allele is associated with better prognosis in cryptogenic cerebrovascular events. Our findings suggest that the α2AP Arg407Lys polymorphism could be involved in the pathogenesis of cerebral ischemia and its outcomes. PMID: 29306602 [PubMed - as supplied by publisher]
Source: Neurologia i Neurochirurgia Polska - December 26, 2017 Category: Neurology Authors: Wzorek J, Karpiński M, Wypasek E, Michalski M, Szczudlik A, Malinowski KP, Undas A Tags: Neurol Neurochir Pol Source Type: research

Response: Heroin Use Could Also Be Associated with Ruptured Aortic Aneurysms
Source: Translational Stroke Research - January 9, 2018 Category: Neurology Source Type: research

Arterial smooth muscle dynamics in development and repair.
Abstract Arterial vasculature distributes blood from early embryonic development and provides a nutrient highway to maintain tissue viability. Atherosclerosis, peripheral artery diseases, stroke and aortic aneurysm represent the most frequent causes of death and are all directly related to abnormalities in the function of arteries. Vascular intervention techniques have been established for the treatment of all of these pathologies, yet arterial surgery can itself lead to biological changes in which uncontrolled arterial wall cell proliferation leads to restricted blood flow. In this review we describe the intricat...
Source: Developmental Biology - February 1, 2018 Category: Biology Authors: Roostalu U, Wong JK Tags: Dev Biol Source Type: research

Cilostazol Attenuates Angiotensin II-Induced Abdominal Aortic Aneurysms but Not Atherosclerosis in Apolipoprotein E-Deficient Mice.
CONCLUSIONS: Cilostazol attenuated angiotensin II-induced AAA formation by its anti-inflammatory effect through phosphodiesterase III inhibition in the aortic wall. Cilostazol may be a promising new therapeutic option for AAAs. PMID: 29437572 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - February 8, 2018 Category: Cardiology Authors: Umebayashi R, Uchida HA, Kakio Y, Subramanian V, Daugherty A, Wada J Tags: Arterioscler Thromb Vasc Biol Source Type: research

Unrecognized Cardiovascular Emergencies Among Medicare Patients
This cohort study estimates the proportions of emergency department visits attributable to symptoms of imminent ruptured abdominal aortic aneurysm, acute myocardial infarction, stroke, aortic dissection, and subarachnoid hemorrhage that end in discharge without diagnosis.
Source: JAMA Internal Medicine - February 26, 2018 Category: Internal Medicine Source Type: research

Early outcomes of patients transferred with ruptured suprarenal aneurysm or dissection.
Conclusions Although the number of patients with rSRAD is low and those who are transferred alive are a self-selecting group, this study suggests that transfer of such patients to a specialist vascular centre is associated with acceptable mortality rates following emergency complex aortic repair. PMID: 29484940 [PubMed - as supplied by publisher]
Source: Annals of the Royal College of Surgeons of England - February 27, 2018 Category: Surgery Authors: Rudarakanchana N, Hamady M, Harris S, Afify E, Gibbs R, Bicknell CD, Jenkins MP Tags: Ann R Coll Surg Engl Source Type: research

Optimizing medical treatment of abdominal aortic aneurysm: Interest of vascular centers.
Abstract Diagnosis of abdominal aortic aneurysm (AAA) at preoperative stage is increasingly frequent. It carries both a local risk of rupture and an increased global cardiovascular risk. Patients with AAA have indeed a 20 times higher risk of dying from myocardial infarction or stroke than from a ruptured aneurysm. Cardiovascular risk factors control is therefore essential, particularly smoking cessation. Treatment in cardiovascular prevention is also warranted. Seeking for atheromatous sites is needed as they determine prognosis. Evidence of the benefit of medical treatment to slow AAA growth is still lacking. In...
Source: Presse Medicale - February 27, 2018 Category: General Medicine Authors: Madika AL, Mounier-Vehier C, Azzaoui R Tags: Presse Med Source Type: research

Prevalence of Abdominal Aortic Aneurysms in the General Population and in Subgroups at High Cardiovascular Risk in Italy. Results of the RoCAV Population Based Study.
CONCLUSIONS: In the study population, both a general screening program in 65-75 year old men and an approach targeted to subgroups at higher risk merit evaluation in a cost-effectiveness study. In 50-64 year old men, strategies for population selection should consider CVD risk stratification tools. PMID: 29506942 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - March 2, 2018 Category: Surgery Authors: Gianfagna F, Veronesi G, Tozzi M, Tarallo A, Borchini R, Ferrario MM, Bertù L, Montonati A, Castelli P, RoCAV (Risk of Cardiovascular diseases and abdominal aortic Aneurysm in Varese) Project Investigators Tags: Eur J Vasc Endovasc Surg Source Type: research

EVAR for aortic abdominal aneurysms: A 20-year's experience of 1900  patients.
[EVAR for aortic abdominal aneurysms: A 20-year's experience of 1900 patients]. Presse Med. 2018 Mar 11;: Authors: Desgranges P, Kobeiter H, Cochennec F, Tacher V, Touma J, Majewski M, Marzelle J, Allaire É, Becquemin JP Abstract Abdominal aortic aneurysms (AAA), also called "silent killer" as they grow without symptoms until the final rupture, are the 3rd cause of cardiovascular deaths, after myocardial infarction and stroke. Surgery is the only efficient way of preventing aortic rupture. The initial technique, described by Charles Dubost in 1952 has evolved and results and provides fair long-term ...
Source: Presse Medicale - March 11, 2018 Category: General Medicine Authors: Desgranges P, Kobeiter H, Cochennec F, Tacher V, Touma J, Majewski M, Marzelle J, Allaire É, Becquemin JP Tags: Presse Med Source Type: research

Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599  912 current drinkers in 83 prospective studies
Publication date: 14–20 April 2018 Source:The Lancet, Volume 391, Issue 10129 Author(s): Angela M Wood, Stephen Kaptoge, Adam S Butterworth, Peter Willeit, Samantha Warnakula, Thomas Bolton, Ellie Paige, Dirk S Paul, Michael Sweeting, Stephen Burgess, Steven Bell, William Astle, David Stevens, Albert Koulman, Randi M Selmer, W M Monique Verschuren, Shinichi Sato, Inger Njølstad, Mark Woodward, Veikko Salomaa, Børge G Nordestgaard, Bu B Yeap, Astrid Fletcher, Olle Melander, Lewis H Kuller, Beverley Balkau, Michael Marmot, Wolfgang Koenig, Edoardo Casiglia, Cyrus Cooper, Volker Arndt, Oscar H Franco, Patrik Wennberg, Jo...
Source: The Lancet - April 13, 2018 Category: General Medicine Source Type: research