Cilostazol Attenuates Angiotensin II-Induced Abdominal Aortic Aneurysms but Not Atherosclerosis in Apolipoprotein E-Deficient Mice.

CONCLUSIONS: Cilostazol attenuated angiotensin II-induced AAA formation by its anti-inflammatory effect through phosphodiesterase III inhibition in the aortic wall. Cilostazol may be a promising new therapeutic option for AAAs. PMID: 29437572 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29437572?dopt=Abstract

Source: Arteriosclerosis, Thrombosis and Vascular Biology - February 8, 2018 Category: Cardiology Authors: Umebayashi R, Uchida HA, Kakio Y, Subramanian V, Daugherty A, Wada J Tags: Arterioscler Thromb Vasc Biol Source Type: research