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MassDevice.com +5 | The top 5 medtech stories for August 25, 2017
Say hello to MassDevice +5, a bite-sized view of the top five medtech stories of the day. This feature of MassDevice.com’s coverage highlights our 5 biggest and most influential stories from the day’s news to make sure you’re up to date on the headlines that continue to shape the medical device industry. Get this in your inbox everyday by subscribing to our newsletters.   5. This tissue paper is made from actual organ tissues Northwestern University researchers have created biomaterials made from animal organs and tissues that could potentially support natural hormone production in young cancer pat...
Source: Mass Device - August 25, 2017 Category: Medical Devices Authors: MassDevice Tags: News Well Plus 5 Source Type: news

Ra Medical CEO Irwin aims for Feb 2018 IPO
In May, Ra Medical received a nod from the FDA for its Dabra arteriosclerosis laser, clearing it for use in the US. It was a decision the company had been waiting on for approximately 3 years, CEO Dean Irwin told MassDevice.com in an interview, and signaled a significant shift forward. “In 2014, we submitted to the FDA, and here in 2017, just on May 24th, we received the go ahead to begin marketing in the United States,” Irwin said. Ra Medical won CE Mark approval in the European Union last October, giving the company time to launch in the region, which it’s been operating in for several mo...
Source: Mass Device - August 24, 2017 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Cardiovascular Regulatory/Compliance Ra Medical Source Type: news

Thieme and Schattauer launch new open access journal TH Open
Thieme has joined forces with Schattauer Publishers to launch a new open access journal: TH Open. It will provide updates on the latest developments in vascular medicine, complementing Schattauer’s established subscription title Thrombosis and Haemostasis. The new open access journal will follow the PWYW (pay what you want) pricing strategy, which leaves the decision of how much the publication of an article in the new English-language journal is worth up to the author. TH Open will be officially introduced at the ISTH 2017 Congress, the global meeting in thrombosis, hemostasis and vascular biology to be held in Berl...
Source: News from STM - July 5, 2017 Category: Databases & Libraries Authors: STM Publishing News Tags: Featured Open Access Source Type: news

Snake venom is key ingredient in experimental drug for heart patients
An experimental antiplatelet drug has surprising bite. Based on a protein found in snake venom, the new drug prevented blood clotting in mice without causing excessive bleeding after an injury, according to research published Thursday in the journal Arteriosclerosis, Thrombosis and Vascular Biology. The drug has yet to be tested in humans. (Source: CNN.com - Health)
Source: CNN.com - Health - June 8, 2017 Category: Consumer Health News Source Type: news

Snake venom is key ingredient in experimental antiplatelet drug
An experimental antiplatelet drug has surprising bite. Based on a protein found in snake venom, the new drug prevented blood clotting in mice without causing excessive bleeding after an injury, according to research published Thursday in the journal Arteriosclerosis, Thrombosis and Vascular Biology. The drug has yet to be tested in humans. (Source: CNN.com - Health)
Source: CNN.com - Health - June 8, 2017 Category: Consumer Health News Source Type: news

Bathroom scales will inform about life threatening conditions
(Kaunas University of Technology) Weighing oneself has become one of the most common morning rituals. However, your weight is not the only message that can be delivered by your bathroom scales: the team of researchers at Kaunas University of Technology (KTU) Institute of Biomedical Engineering are developing the multifunctional scales, which can monitor your health and inform about potentially dangerous life conditions, such as arteriosclerosis or cardiac arrhythmia. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - May 16, 2017 Category: Biology Source Type: news

Well : Heart Healthy in the Amazon
What some Bolivians with the world ’ s healthiest arteries might tell us about cardiac fitness. (Source: NYT Health)
Source: NYT Health - April 6, 2017 Category: Consumer Health News Authors: GRETCHEN REYNOLDS Tags: Heart Arteriosclerosis and Atherosclerosis Archaeology and Anthropology Carbohydrates Diet and Nutrition Age, Chronological Source Type: news

New unknown risk factor for arteriosclerosis identified
Following a blood infection, the first class of antibodies produced by the immune system are IgM antibodies. They form the " vanguard " of the immune response, before other cells are activated to fight the infection. Some people are deficient or completely lack these antibodies, so that they develop congenital immune deficiency. Researchers have now discovered how this deficiency can also lead to an increased risk of arteriosclerosis and consequently even to serious cardiovascular diseases. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 9, 2017 Category: Science Source Type: news

Smokers have higher lifetime risk of abdominal aortic aneurysm
This study adds to the literature by reporting AAA lifetime risk from a community-based cohort with long follow-up,” Tang told Reuters Health by email. The researchers used data from more than 15,000 middle-aged people who were at risk of developing AAA based on an initial assessment between 1987 and 1989. The participants made three subsequent visits for exams and assessments through 1998. Nearly 6,000 people were still alive between 2011 and 2013 and underwent an ultrasound exam at a fifth assessment visit then. Over the 22-year follow-up period, there were 590 diagnosed, ruptured or repaired AAAs. In 2011, the ult...
Source: Mass Device - November 17, 2016 Category: Medical Equipment Authors: MassDevice Tags: Vascular Source Type: news

To the Brain and Back - "Fantastic Voyage" pulsed by Anatomy from Asimov
Autumn 1966: A Medical Operation that's critical to Military Operations - ... an operation vitally urgent to the security of the free world... a voyage into inner space, into the living body, via a submarine and everyone in it shrunk down to the size of a single cell... inserted hypodermically and transported by the body's circulatory system, through the heart and the lungs, into the brain... so that a laser beam might dissolve a life-threatening blood clot, in a brain that holds an earth-imperiling secret.... ... $4 million will be spent to make this milestone of entertainment and showmanship. That was the 1966 promoti...
Source: Science - The Huffington Post - November 15, 2016 Category: Science Source Type: news

Late Failing Heart AllograftsLate Failing Heart Allografts
Learn more about the role of antibody-mediated rejection and coronary arteriosclerosis in late failing heart allografts. American Journal of Transplantation (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - February 23, 2016 Category: Transplant Surgery Tags: Transplantation Journal Article Source Type: news

Asthma Diagnosis Tied to Higher Risk for Abdominal Aortic Aneurysm Rupture (FREE)
By Kelly Young Edited by André Sofair, MD, MPH, and William E. Chavey, MD, MS A recent diagnosis of asthma is associated with higher risk for rupture in older patients with abdominal aortic aneurysm (AAA), according to an observational study in Arteriosclerosis, Thrombosis … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - February 12, 2016 Category: Primary Care Source Type: news

Sleep Fragmentation Linked to Cerebrovascular Pathology Sleep Fragmentation Linked to Cerebrovascular Pathology
Greater sleep fragmentation -- defined as interruption of sustained sleep by repeated awakenings -- is associated with arteriosclerosis and subcortical infarcts at autopsy. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 14, 2016 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Consumer Health Tips: How to Avoid Medication Errors
Medication errors: Cut your risk with these tips Grapefruit: Beware of dangerous medication interactions Too much vitamin C: Is it harmful? Chronic stress: Can it cause depression? Arteriosclerosis/atherosclerosis overview   (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - January 7, 2016 Category: Databases & Libraries Source Type: news

Control Inflammation and “Turn Off” Disease-Causing Genes
The single most important thing you can do to prevent premature aging is to control inflammation. Inflammation is the body’s effort to heal itself. But too much produces disease. In fact, most of the diseases associated with aging are essentially inflammatory diseases. That includes cancer, heart disease, arthritis, arteriosclerosis, Alzheimer’s disease and diabetes. And the truth is that we’re all inflamed thanks to a modern diet that includes inflammation-friendly ingredients like sugar, cheap vegetable oils, and refined carbohydrates. Most doctors are not educated in the role of nutrition in disease. A...
Source: Al Sears, MD Natural Remedies - September 15, 2015 Category: Complementary Medicine Authors: Dr. Al Sears Tags: Anti-Aging food allergies inflammation natural healing turmeric Source Type: news

Sleep Problems May Hint At Future Heart Disease Risk
By Kathryn Doyle (Reuters Health) - Adults who get too much or too little sleep may have the beginnings of “hardening" of the arteries, which can be an early sign of heart disease, according to a new study. “Many people, up to one third or one fourth of the general population, suffer from inadequate sleep – either insufficient duration of sleep or poor quality of sleep,” said co-lead author Dr. Chan-Won Kim of Kangbuk Samsung Hospital of Sungkyunkwan University School of Medicine in Seoul, South Korea. Several studies have linked inadequate sleep with an increased risk of heart attack and strok...
Source: Healthy Living - The Huffington Post - September 10, 2015 Category: Consumer Health News Source Type: news

Save Your Brain
Alzheimer’s is one of the most devastating and dreaded diseases I’m confronted with at my South Florida anti-aging clinic. And because I’m based in a part of the country that’s a major retirement Mecca, I see more seniors than the average American physician – and proportionally more Alzheimer’s sufferers. Many patients fear Alzheimer’s more than cancer or any other debilitating disease. They’re terrified of this cruel, progressive and degenerative illness that attacks the brain, steals memory, confuses thinking, and can turn even the most intelligent and achieving adults into...
Source: Al Sears, MD Natural Remedies - May 6, 2015 Category: Complementary Medicine Authors: Dr. Al Sears Tags: Anti-Aging Brain Health Nutrition Alzheimer's disease arginine dementia logic memory nutrients Source Type: news

Breakthrough identification of important protein
Danish researchers are the first in the world to develop a secure way of measuring the important protein apo-M. This could prove relevant for research into diseases such as diabetes, arteriosclerosis and sclerosis, they say. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 23, 2015 Category: Science Source Type: news

Why You Should Avoid Statins
At my anti-aging clinic, I continue to wage war against what I call the “medical-industrial complex.” And I do it for one reason only – I care more about my patients than I do about profits. Big Pharma clearly takes the opposite view. And now it seems these pharmaceutical behemoths won’t be happy until every man, woman and child is popping anti-cholesterol pills. Researchers at Duke University recently issued a report recommending that even children and people as young as 30 should be on statins, if they have just slightly elevated cholesterol levels.1 And why wouldn’t researchers at Duke reco...
Source: Al Sears, MD Natural Remedies - February 3, 2015 Category: Complementary Medicine Authors: Dr. Al Sears Tags: Heart Health Source Type: news

Sunshine and Telomeres
A warm sunny day … what could feel better? Yet the warm sun on our skin that we all crave gets a lot of bad press from the medical establishment. Far from being a source of illness that will kill you before your time, the sun is your best hope to live longer and prevent illness. Did you know, for example, that people living in places that get more of the sun’s UV radiation have the lowest incidence of cancer?1 That doesn’t mean sunlight lowers the “risk” of getting cancer. Getting more sunlight keeps people from actually getting cancer. Studies show sunlight prevents skin cancer, prostate2 ca...
Source: Al Sears, MD Natural Remedies - January 23, 2015 Category: Complementary Medicine Authors: Dr. Al Sears Tags: Anti-Aging telomerase telomeres vitamin D Source Type: news

Dare to Be 100: Fat, Carbs, Calories
These three items were the centerpiece of my early science life. I wrote my honors thesis at Williams College about arteriosclerosis which at that time was considered to be heavily influenced by dietary fat. Then after medical school I entered a wonderful time of life learning much about F, Cs, and Cs. The 1960s overflowed. The high point of those years was those spent in the intellectual and physical embrace of two multi-million dollar research grants from the NIH. The first dealt with the control of cholesterol synthesis, and the second "The Effect of Diet on the Metabolism of Fat In Man." This second grant su...
Source: Healthy Living - The Huffington Post - January 23, 2015 Category: Consumer Health News Source Type: news

Ask Well: Blockages in the Heart and Brain
A reader asks: Why do people get blockages in the arteries of the heart and brain, but rarely in other organs? (Source: NYT Health)
Source: NYT Health - January 5, 2015 Category: Consumer Health News Authors: By ANAHAD O'CONNOR Tags: Heart Body Brain Stroke Arteriosclerosis and Atherosclerosis Featured Source Type: news

Ask Well: Blockages in the Heart and Brain
A reader asks: Why do people get blockages in the arteries of the heart and brain, but rarely in other organs? (Source: NYT)
Source: NYT - January 5, 2015 Category: Nutrition Authors: By ANAHAD O'CONNOR Tags: Heart Body Brain Stroke Arteriosclerosis and Atherosclerosis Featured Source Type: news

Well: Ask Well: Blockages in the Heart and Brain
A reader asks: Why do people get blockages in the arteries of the heart and brain, but rarely in other organs? (Source: NYT)
Source: NYT - January 5, 2015 Category: American Health Authors: By ANAHAD O'CONNOR Tags: Heart Body Brain Stroke Arteriosclerosis and Atherosclerosis Featured Source Type: news

Books: Martha Weinman Lear Returns to Medical Memoir, With Less Fury, in ‘Echoes of Heartsounds’
Martha Weinman Lear returns to the territory she covered in “Heartsounds,” but this is not a sequel so much as a rueful epilogue, a brief account of her own recent skirmish with heart disease. (Source: NYT Health)
Source: NYT Health - October 27, 2014 Category: Consumer Health News Authors: By ABIGAIL ZUGER, M.D. Tags: Lear, Martha Weinman Heart Echoes of Heartsounds (Book) Health Insurance and Managed Care Arteriosclerosis and Atherosclerosis Books and Literature Source Type: news

New research can improve heart health
(University of Copenhagen) For the first time, researchers at the University of Copenhagen and Rigshospitalet are able to show that a particular gene variant lowers the risk of arteriosclerosis by 41 percent, making the variant an obvious target for future drugs for cardiovascular disease treatment. The results are based on data from nearly 76,000 subjects and have just been published in the renowned New England Journal of Medicine. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 18, 2014 Category: Biology Source Type: news

Attack is not always the best defense
(Friedrich-Schiller-Universitaet Jena) For many inflammatory diseases as asthma, rheumatism, arteriosclerosis and cancer there are only few effective therapies. But now pharmacists at Jena University developed three new drug candidates against inflammation. The scientists present the potential therapeutic agents in the British Journal of Pharmacology and the Journal of Medical Chemistry. The agents are able to suppress a key enzyme in the body's own cascade of inflammation. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 27, 2014 Category: Global & Universal Source Type: news

Novel marker and possible therapeutic target for cardiovascular calcification identified
(Brigham and Women's Hospital) Led by Dr. Aikawa, a team of researchers at BWH and Kowa Company, Ltd., a Japanese pharmaceutical company, has discovered certain proteins in osteoclasts, a precursor to bone, that may be used in helping to destroy cardiovascular calcification by dissolving mineral deposits. The research, described in the March 2014 issue of Arteriosclerosis, Thrombosis, and Vascular Biology, suggests a potential therapeutic avenue for patients with cardiovascular calcification. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 13, 2014 Category: Global & Universal Source Type: news

New coating may reduce blood clot risk inside stents
Coating artery-opening stents with a new compound may someday eliminate a common side effect of the treatment, according to preliminary research in the American Heart Association journal Arteriosclerosis, Thrombosis, and Vascular Biology. Stents are tiny mesh tubes that prop open clogged arteries so blood will flow freely to heart muscle, relieving chest pain and reducing the risk of heart attack... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 9, 2013 Category: Consumer Health News Tags: Surgery Source Type: news

Chest Pain Patients Could Get Quick DNA Test for Heart Problems
Testing fragments of DNA in the blood may be a fast way to find out if a patient's chest pain is due to coronary artery disease according to a new US-led study published online this week in the journal Arteriosclerosis, Thrombosis, and Vascular Biology. When patients complain of chest pain, they have to undergo a time-consuming and expensive set of tests to find out if the cause is something to do with the heart or some other problem, such as in the muscles, lungs or esophagus... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 2, 2013 Category: Consumer Health News Tags: Heart Disease Source Type: news

Researchers Identify Target To Prevent Hardening Of Arteries
The hardening of arteries is a hallmark of atherosclerosis, an often deadly disease in which plaques, excessive connective tissue, and other changes build up inside vessel walls and squeeze off the flow of oxygen-rich blood throughout the body. Now, researchers at Sanford-Burnham Medical Research Institute have described the molecular and cellular pathway that leads to this hardening of the arteries - and zeroed in on a particularly destructive protein called Dkk1. Their study was published online today by Arteriosclerosis, Thrombosis, and Vascular Biology... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 20, 2013 Category: Consumer Health News Tags: Vascular Source Type: news

The Life Threatening Toll of Stress
New research confirms the life threatening toll of stress. What can you do to combat stress and break this cycle? read more (Source: Psychology Today Anxiety Center)
Source: Psychology Today Anxiety Center - May 18, 2013 Category: Psychiatry & Psychology Authors: Christopher Bergland Tags: Anxiety Depression Health Stress arteriosclerosis biomarker clinical depression depressed patient hardening of the arteries heart disease heart disease patients inflammatory response interleukin 6 loyola university medical center Source Type: news

Jekyll into Hyde: Breathing auto emissions turns HDL cholesterol from 'good' to 'bad'
Academic researchers have found that breathing motor vehicle emissions triggers a change in high-density lipoprotein (HDL) cholesterol, altering its cardiovascular protective qualities so that it actually contributes to clogged arteries.    In addition to changing HDL from "good" to "bad," the inhalation of emissions activates other components of oxidation, the early cell and tissue damage that causes inflammation, leading to hardening of the arteries, according to the research team, which included scientists from UCLA and other institutions.   The findings of this early study, done in mi...
Source: UCLA Newsroom: Health Sciences - May 15, 2013 Category: Universities & Medical Training Source Type: news

Well: Safety: Air Pollution Tied to Heart Disease
Following more than 5,000 people in six cities and air pollution data, researchers found that the greater the level of air pollution, the greater the thickening of the carotid artery, a known risk for heart attack and stroke.     (Source: NYT Health)
Source: NYT Health - May 2, 2013 Category: Consumer Health News Authors: By NICHOLAS BAKALAR Tags: Heart Air Pollution Body Carotid Arteries Arteriosclerosis and Atherosclerosis Featured Source Type: news

Diet, 'Anti-Aging' Supplements May Help Reverse Blood Vessel Abnormality
A diet low in grains, beans and certain vegetables - combined with "anti-aging" supplements - improved blood vessel function, in a study presented at the American Heart Association's Arteriosclerosis, Thrombosis and Vascular Biology 2013 Scientific Sessions. The blood vessel abnormality, or endothelial dysfunction, occurs when cells lining the interior wall of blood vessels malfunction. It's a serious condition that's often one of the first signs of heart disease. Of the 200 51- to 86-year-old people in the study, 40 percent were women... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 2, 2013 Category: Consumer Health News Tags: Cardiovascular / Cardiology Source Type: news

Walking Reduces Heart Risk As Much As Running
Brisk walking can reduce a person's risk of diabetes, high blood pressure, and high cholesterol just as much as running can. The finding came from a new study published in the journal Arteriosclerosis, Thrombosis and Vascular Biology which examined 33,060 runners in the National Runners' Health Study and 15,045 walkers in the National Walkers' Health Study... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 5, 2013 Category: Consumer Health News Tags: Sports Medicine / Fitness Source Type: news

Study Of Blood Plasma Improves Our Understanding Of Thrombosis, Aneurysms And Arteriosclerosis
The results are significant because they can help to improve our understanding of medical conditions, such as thrombosis, aneurysms and arteriosclerosis. The research team is publishing its results in Physical Review Letters and the American Physical Society has highlighted the work on its Physics website*, placing it on the Focus List of important physics news. Blood flows differently than water. Anyone who has ever cut themselves knows that blood flows viscously and rather erratically. The similarity between blood and ketchup is something not only filmmakers are aware of... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 20, 2013 Category: Consumer Health News Tags: Vascular Source Type: news

Low vitamin D levels proven to be deadly, increase mortality
The most comprehensive epidemiological review ever conducted on the association between vitamin D and mortality has revealed that low vitamin D levels are directly linked to early death from heart disease and other causes. Published in the journal Arteriosclerosis, Thrombosis... (Source: NaturalNews.com)
Source: NaturalNews.com - February 13, 2013 Category: Consumer Health News Source Type: news

Quinoa brings riches to the Andes
Bolivian and Peruvian farmers sell entire crop to meet rising western demand, sparking fears of malnutritionA burst of colour on a monochromatic panorama, a field of flowering quinoa plants in the Bolivian desert is a thing of beauty. A plant ready for harvest can stand higher than a human, covered with knotty blossoms, from violet to crimson and ochre-orange to yellow.Quinua real, or royal quinoa, flourishes in the most hostile conditions, surviving nightly frosts and daytime temperatures upwards of 40C (104F). It is a high-altitude plant, growing at 3,600 metres above sea level and higher, where oxygen is thin, water is ...
Source: Guardian Unlimited Science - January 14, 2013 Category: Science Authors: Dan Collyns Tags: Nutrition The Guardian Peru Americas World news Food & drink Bolivia Life and style Business Agriculture Nutrition and development Source Type: news

RAGE Splicing Variants in Mammals
The receptor for advanced glycation end products (RAGE) is a multiligand receptor of environmental stressors which plays key roles in pathophysiological processes, including immune/inflammatory disorders, Alzheimer’s disease, diabetic arteriosclerosis, tumorigenesis, and metastasis. Besides the full-length RAGE protein in humans nearly 20 natural occurring RAGE splicing variants were described on mRNA and protein level. These naturally occurring isoforms are characterized by either N-terminally or C-terminally truncations and are discussed as possible regulators of the full-length RAGE receptor either by competitive ...
Source: Springer protocols feed by Protein Science - January 1, 2013 Category: Biochemistry Source Type: news