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Condition: Aortic Aneurysm

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Total 540 results found since Jan 2013.

Moderate Versus Deep Hypothermic Circulatory Arrest for Elective Aortic Transverse Hemiarch Reconstruction.
CONCLUSIONS: MHCA with antegrade cerebral perfusion yields excellent and equivalent outcomes to DHCA for elective aortic hemiarch reconstruction. MHCA significantly improves intraoperative times and, importantly, reduces transfusion requirements compared with DHCA with a retrograde cerebral perfusion strategy. PMID: 25825200 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - March 27, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Vallabhajosyula P, Jassar AS, Menon RS, Komlo C, Gutsche J, Desai ND, Hargrove WC, Bavaria JE, Szeto WY Tags: Ann Thorac Surg Source Type: research

Genome-wide association studies of late-onset cardiovascular disease
Human genetics is a powerful tool for discovering causal mediators of human disease and physiology. Cardiovascular diseases with late onset in the lifecourse have historically not been considered genetic diseases, but in recent years the contribution of a heritable factor has been established. More importantly, over the last decade genome-wide association studies (GWASs) have identified many loci associated with late-onset cardiovascular diseases including coronary artery disease, carotid artery disease, ischemic stroke, aortic aneurysm, peripheral vascular disease, atrial fibrillation, valvular disease and correlates of myocardial function.
Source: Journal of Molecular and Cellular Cardiology - April 10, 2015 Category: Cytology Authors: J. Gustav Smith, Christopher Newton-Cheh Source Type: research

Evolution in the Management of Aberrant Subclavian Arteries and Related Kommerell Diverticulum
Conclusions Aberrant subclavian arteries and associated Kommerell diverticulum can be treated with acceptable rates of mortality and morbidity. The evolution toward an endovascular approach did not appear to affect late outcomes, suggesting that the choice of treatment should be based on patient-specific anatomy and associated comorbidities.
Source: The Annals of Thoracic Surgery - April 23, 2015 Category: Cardiovascular & Thoracic Surgery Source Type: research

Recent thoraco-abdominal aortic repair outcomes using moderate-to-deep hypothermia combined with targeted reconstruction of the Adamkiewicz artery
CONCLUSIONS Moderate-to-deep hypothermia combined with targeted reconstruction of the AKA provided satisfactory outcomes with thoraco-abdominal aortic repair, particularly for spinal cord protection.
Source: Interactive CardioVascular and Thoracic Surgery - April 22, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Tanaka, H., Minatoya, K., Sasaki, H., Seike, Y., Itonaga, T., Oda, T., Kobayashi, J. Tags: Pericardium Adult Cardiac Source Type: research

Evolution in the Management of Aberrant Subclavian Arteries and Related Kommerell Diverticulum.
CONCLUSIONS: Aberrant subclavian arteries and associated Kommerell diverticulum can be treated with acceptable rates of mortality and morbidity. The evolution toward an endovascular approach did not appear to affect late outcomes, suggesting that the choice of treatment should be based on patient-specific anatomy and associated comorbidities. PMID: 25912743 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - April 23, 2015 Category: Cardiovascular & Thoracic Surgery Authors: van Bogerijen GH, Patel HJ, Eliason JL, Criado E, Williams DM, Knepper J, Yang B, Deeb GM Tags: Ann Thorac Surg Source Type: research

Neuroprotection After Major Cardiovascular Surgery
Opinion statement Neurologic injury is a common complication of major cardiovascular procedures including coronary artery bypass graft (CABG) surgery, coronary valve replacement, and aortic aneurysm surgery. However, despite ongoing research in the field of neuroprotection, there are currently few pharmacologic and interventional options to effectively protect the brain and spinal cord in the postoperative period. CSF drainage after aortic surgery currently stands as the only neuroprotective intervention that has been consistently shown to protect the spinal cord from ischemic injury, leading to significantly few...
Source: Current Treatment Options in Neurology - May 15, 2015 Category: Neurology Source Type: research

Systematic review of cardiovascular disease and cardiovascular death in patients with a small abdominal aortic aneurysm
ConclusionThe risk of cardiovascular death in patients with a small AAA is high and increases by approximately 3 per cent each year after diagnosis. Patients with a small AAA have a high prevalence of cardiovascular disease. Patients a small AAA should be considered for lifestyle modifications and secondary cardiovascular protection.
Source: British Journal of Surgery - May 14, 2015 Category: Surgery Authors: M. F. Bath, V. J. Gokani, D. A. Sidloff, L. R. Jones, E. Choke, R. D. Sayers, M. J. Bown Tags: Systematic review Source Type: research

Abstract 250: Real-world Rates and Costs of Heart Failure Events Among Patients with Hyperlipidemia Session Title: Poster Session II
Conclusions: The rate and recurrence of heart failure among hyperlipidemic patients is very high and the long term healthcare costs substantial in this real-world 2-year study.
Source: Circulation: Cardiovascular Quality and Outcomes - April 29, 2015 Category: Cardiology Authors: Fox, K. M., Punekar, R. S., Richhariya, A., Fisher, M. D., Gandra, S. R., Cziraky, M. J., Toth, P. P. Tags: Session Title: Poster Session II Source Type: research

Abstract 263: Incidence of Recurrent Cardiovascular Events and Disease Burden Among High-Risk Patients with Hyperlipidemia Session Title: Poster Session II
Conclusions: CV event-related risk and long-term costs are significantly greater among high-risk patients with shorter time intervals between recurrent CV events. Underutilization of LLTs in these patients highlights the need for improving clinical management and treatment options for these patients.
Source: Circulation: Cardiovascular Quality and Outcomes - April 29, 2015 Category: Cardiology Authors: Punekar, R. S., Fox, K. M., Richhariya, A., Fisher, M. D., Gandra, S. R., Cziraky, M. J., Toth, P. P. Tags: Session Title: Poster Session II Source Type: research

A randomized controlled trial on the effects of goal directed therapy on the inflammatory response open abdominal aortic aneurysm repair
IntroductionGoal directed therapy (GDT) has been shown in numerous studies to decrease perioperative morbidity and morality. The mechanism of benefit of GDT however, has not been clearly elucidated. Targeted resuscitation of the vascular endothelium with GDT might alter the postoperative inflammatory response and be responsible for the decreased complications with this therapy. Methods: This trial was registered at ClinicalTrials.gov as NCT01681251. Forty patients undergoing elective open repair of their abdominal aortic aneurysm (AAA), 18 years of age and older were randomized to an interventional arm with GDT targeting s...
Source: Critical Care - June 10, 2015 Category: Intensive Care Authors: Duane FunkKent HayGlassJoshua KoulackGreg HardingApril BoydRyan Brinkman Source Type: research

Endovascular Repair versus Open Repair for Isolated Descending Thoracic Aortic Aneurysm.
CONCLUSION: TEVAR is safe and effective for treating DTAAs with improved perioperative and long-term outcomes compared with open repair. PMID: 26069110 [PubMed - as supplied by publisher]
Source: Yonsei Medical Journal - June 13, 2015 Category: Universities & Medical Training Authors: Lee HC, Joo HC, Lee SH, Lee S, Chang BC, Yoo KJ, Youn YN Tags: Yonsei Med J Source Type: research

Site-Specific Relationship Between Intracranial Aneurysm and Aortic Aneurysm Brief Reports
Conclusions— The differing distribution patterns of IA among AA groups suggest a site-specific sharing of pathomechanism between the 2 types of aneurysms.
Source: Stroke - June 22, 2015 Category: Neurology Authors: Shin, Y.-W., Jung, K.-H., Moon, J., Lee, S.-T., Lee, S. K., Chu, K., Roh, J.-K. Tags: Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage Brief Reports Source Type: research

Statins and subarachnoid hemorrhage in Medicare patients with unruptured cerebral aneurysms
ConclusionsStatin use by patients with unruptured cerebral aneurysms was not associated with subarachnoid hemorrhage risk. Given the prior animal experimental studies demonstrating a protective effect, further prospective studies are needed to investigate the potential relationship.
Source: International Journal of Stroke - June 29, 2015 Category: Neurology Authors: Kimon Bekelis, Jeremy Smith, Weiping Zhou, Todd A. MacKenzie, David W. Roberts, Jonathan Skinner, Nancy E. Morden Tags: Research Source Type: research

Joni Mitchell's Aneurysm, Explained
Musician Joni Mitchell is recovering from an aneurysm she suffered in March, according to a statement from her conservator, Leslie Morris. Contrary to rumors about her condition, Mitchell can speak, and is going through therapy to help regain the ability to walk again, Morris wrote. Few details have been given about Mitchell’s aneurysm, except that she was found unconscious in her Bel Air home on March 31 and immediately transported to a Los Angeles-area hospital in an ambulance. She’s now resting at home, according to Morris’ latest statement, and a full recovery is expected. Aneurysms are a condition in which th...
Source: Science - The Huffington Post - June 30, 2015 Category: Science Source Type: news

Outcomes of Open Repair of Mycotic Descending Thoracic and Thoracoabdominal Aortic Aneurysms
Conclusions Open repair of mycotic descending thoracic and thoracoabdominal aortic aneurysms remains the gold standard of therapy. Aggressive intraoperative debridement with in situ prosthetic reconstruction permits a high rate of success in this very high risk cohort of patients. Lifelong antibiotic suppression therapy may prevent late prosthetic graft infection.
Source: The Annals of Thoracic Surgery - August 14, 2015 Category: Cardiovascular & Thoracic Surgery Source Type: research