Optimizing medical treatment of abdominal aortic aneurysm: Interest of vascular centers.

[Optimizing medical treatment of abdominal aortic aneurysm: Interest of vascular centers]. Presse Med. 2018 Feb 27;: Authors: Madika AL, Mounier-Vehier C, Azzaoui R Abstract Diagnosis of abdominal aortic aneurysm (AAA) at preoperative stage is increasingly frequent. It carries both a local risk of rupture and an increased global cardiovascular risk. Patients with AAA have indeed a 20 times higher risk of dying from myocardial infarction or stroke than from a ruptured aneurysm. Cardiovascular risk factors control is therefore essential, particularly smoking cessation. Treatment in cardiovascular prevention is also warranted. Seeking for atheromatous sites is needed as they determine prognosis. Evidence of the benefit of medical treatment to slow AAA growth is still lacking. In practice, it is recommended to prescribe statins and angiotensin converting enzyme inhibitor to prevent cardiovascular events. These preventive measures are as well necessary to improve postoperative prognosis and must be continued after surgical repair. A vascular medical and surgical cooperation is primordial to enhance comprehensive management of patients with AAA. PMID: 29499996 [PubMed - as supplied by publisher]
Source: Presse Medicale - Category: General Medicine Authors: Tags: Presse Med Source Type: research

Related Links:

(Medical College of Georgia at Augusta University) Eight months of daily, afterschool physical activity in previously inactive 8- to 11-year-olds with obesity and overweight improved key measures of their cardiovascular health like good cholesterol levels, aerobic fitness and percent body fat, but didn't improve others like arterial stiffness, an early indicator of cardiovascular risk, Medical College of Georgia investigators report.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
The objective of the work was to develop the marine-derived polysaccharides attenuating 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR), and as prospective natural anti-dyslipidemic leads. Physical and chromatographic purification methods were used to isolate the polygalactofucan from the marine macroalgaSargassum wightii andβ-(2-deoxy)-amino-substituted glucopyrananan from a marine crustacean. Glycosidic linkage analysis by the process of methylation was used for structural elucidation of the polygalactofucan, and the methylated and partially methylated alditol acetates were characterized using extensive spectroscop...
Source: Medicinal Chemistry Research - Category: Chemistry Source Type: research
Authors: Zhang H, Wang Y, Yang G, Yu H, Zhou Z, Tang M Abstract Cartilage injury is difficult to repair since the cartilage tissue lacks self-restoration ability. Improved formation of chondrocytes differentiated from the mesenchymal stem cells (MSC) by genetic regulation is a potentially promising therapeutic option. SOX9 is a critical transcription factor for mesenchymal condensation prior to chondrogenesis. Previous studies demonstrated that several microRNAs (miRNAs or miRs) play a critical role in the chondrogenic differentiation of MSCs. However, the interactional relations between miR-30a and SOX9 during cho...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Publication date: 1 January 2020Source: Colloids and Surfaces B: Biointerfaces, Volume 185Author(s): Wan Bei, Li Jing, Nie ChenAbstractWogonin, one of the main active ingredients of Scutellaria radix, is a kind of flavonoid compound. In the present study, we report that wogonin nanoparticles (Wog np) protect Isoproterenol (ISO) induced Myocardial Infarction (MI) rats. Nanoparticles of sizes less than 200 nm with spherical shape were prepared using Polylactic-co-glycolic acid (PLGA) and Polyvinyl alcohol (PVA) respectively as polymer and stabilizer. Male Wistar rats were divided into 4 groups. Group 1 as a control group a...
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
All people are the same; only their habits differ. ~ Confucius This is a post about what keeps us stuck and sets us free, about the good news behind bad luck, and the wrong way to want the right thing: It’s about our habits. Human beings are creatures of habit — even emotionally. But why is this? Why do we fall into routines? And why is it so hard to break a habit? The short answer is something called set point. You’re probably familiar with this idea if you have ever been on a diet or had a new year’s resolution. They both start well. You are going to make a change in your life and you are ready fo...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Habits Happiness Proof Positive Self-Help Appreciation Gratitude habituation Source Type: blogs
Purpose of review To summarize recent data on the role of dyslipidaemia and the benefit from managing this in people with disease of the abdominal aorta and its peripheral branches (peripheral artery disease, PAD). Recent findings Findings from the Further Cardiovascular Outcomes Research with Proprotein convertase subtilisin/kexin type 9 (PCSK9) Inhibition in Subjects with Elevated Risk (FOURIER) trial demonstrate the benefit of intensely lowering low-density lipoprotein-cholesterol (LDL-c) in people with PAD to substantially reduce the incidence of major cardiovascular events (MACE; myocardial infarction, stroke or ...
Source: Current Opinion in Lipidology - Category: Lipidology Tags: THERAPY AND CLINICAL TRIALS: Edited by Erik S.G. Stroes and Gerald F. Watts Source Type: research
CONCLUSIONS: This multifaceted screening offer to a general population sample of postmenopausal women had no effects on all cause mortality or hospital admission for MI, IHD, PAD, and stroke within a short-term follow up period. PMID: 29625727 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - Category: Surgery Authors: Tags: Eur J Vasc Endovasc Surg Source Type: research
In conclusion, senescence of vascular cells promotes the development of age-related disorders, including heart failure, diabetes, and atherosclerotic diseases, while suppression of vascular cell senescence ameliorates phenotypic features of aging in various models. Recent findings have indicated that specific depletion of senescent cells reverses age-related changes. Although the biological networks contributing to maintenance of homeostasis are extremely complex, it seems reasonable to explore senolytic agents that can act on specific cellular components or tissues. Several clinical trials of senolytic agents are currentl...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
I hear this comment with some regularity when, for instance, someone recognizes me as the author of the Wheat Belly series. This is a step in the right direction. But saying that you have a wheat intolerance is like saying “I have a tobacco intolerance.” The impact of tobacco smoking on health ranges from mild impairment, to incapacitating diseases such as chronic lung disease and abdominal aortic aneurysms, to death. A rare person escapes the ravages of years of smoking, but most people develop at least one, if not half-a-dozen, health problems from cigarettes. And so it goes with wheat: It’s a rare pers...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Wheat Belly Lifestyle gluten gluten-free grain grain-free grains health Inflammation Source Type: blogs
More News: Abdominal Aneurysm Repair | Abdominal Aortic Aneurysm | Aortic Aneurysm | Cardiology | Cardiovascular | Cholesterol | Gastroschisis Repair | General Medicine | Heart | Heart Attack | Smokers | Statin Therapy | Stroke