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Condition: Dementia
Procedure: Angiography

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Total 45 results found since Jan 2013.

Prevalence of Intracranial Atherosclerotic Stenosis Using High-Resolution Magnetic Resonance Angiography in the General Population: The Atherosclerosis Risk in Communities Study Clinical Sciences
Conclusions— The prevalence of ICAS in older adults is high, and it could be a target for primary prevention of stroke and dementia in this population.
Source: Stroke - April 24, 2016 Category: Neurology Authors: Suri, M. F. K., Qiao, Y., Ma, X., Guallar, E., Zhou, J., Zhang, Y., Liu, L., Chu, H., Qureshi, A. I., Alonso, A., Folsom, A. R., Wasserman, B. A. Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke, Atherosclerosis, Stenosis, Vascular Disease Clinical Sciences Source Type: research

Stimulation of angiotensin II receptor 2 preserves cognitive function and is associated with an enhanced cerebral vascular density after stroke
In conclusion, C21 prevented cognitive impairment after stroke, likely through a mechanism involving vascular protection and restoration.PMID:34481068 | DOI:10.1016/j.vph.2021.106904
Source: Vascular Pharmacology - September 4, 2021 Category: Drugs & Pharmacology Authors: Wael Eldahshan Mohammed A Sayed Mohamed E Awad Heba A Ahmed Ellen Gillis Waleed Althomali Bindu Pillai Abdulkarim Alshammari Ladonya Jackson Guangkuo Dong Jennifer C Sullivan Marion A Cooley Mohammed Elsalanty Adviye Ergul Susan C Fagan Source Type: research

Intracranial and Extracranial Stenosis interact with White Matter Disease in the Pathogenesis of Post Stroke Dementia (P5.210)
Conclusions: Patients with concomitant extracranial and intracranial stenosis have highest risks of developing PSD. Burden of WMH further influences the impact of stenosis on cognition.Disclosure: Dr. Ben Wee has nothing to disclose. Dr. Choong has nothing to disclose. Dr. Chander has nothing to disclose. Dr. Kandiah has received honorarium and CME sponsorship from Lundbeck, Novartis and Eisai.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Ben Wee, C., Choong, A., Chander, R., Kandiah, N. Tags: Aging and Dementia: Disease Models and Mechanisms Source Type: research

The Application of Optical Coherence Tomography Angiography in Cerebral Small Vessel Disease, Ischemic Stroke, and Dementia: A Systematic Review
Conclusions: Changes in retinal microvasculature identified using OCTA are associated with monogenic SVD and different stages of AD, but data are limited and partly confounded by methodological differences. Larger studies with risk factors adjustment and more consistent OCTA methods are needed to fully exploit this technology.PROSPERO registration number: CRD42020166929.
Source: Frontiers in Neurology - September 9, 2020 Category: Neurology Source Type: research

Cadasil in northern ireland: a retrospective clinical, neuroimaging and genetic study
This study demonstrates the wide variability in the phenotype and MRI features of CADASIL.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 14, 2015 Category: Neurosurgery Authors: McMacken, G., McKenna, E., McKee, S., McConville, J. Tags: Dementia, Epilepsy and seizures, Headache (including migraine), Stroke, Memory disorders (psychiatry) Wed 20, Parallel session 4: Disease pathophysiology Source Type: research

Gradual Carotid Artery Stenosis in Mice Closely Replicates Hypoperfusive Vascular Dementia in Humans Stroke
Conclusions The GCAS model successfully generated gradual and continuous CBF reduction over 28 days, with replication of key histological, radiological, and behavioral features associated with cerebral hypoperfusion leading to VCI.
Source: JAHA:Journal of the American Heart Association - February 22, 2016 Category: Cardiology Authors: Hattori, Y., Enmi, J.-i., Iguchi, S., Saito, S., Yamamoto, Y., Tsuji, M., Nagatsuka, K., Kalaria, R. N., Iida, H., Ihara, M. Tags: Animal Models of Human Disease, Cerebrovascular Disease/Stroke, Cognitive Impairment, Atherosclerosis, Stenosis Source Type: research

Brachial-Ankle Pulse Wave Velocity is Related to the Total Cerebral Small-Vessel Disease Score in an Apparently Healthy Asymptomatic Population
Cerebral small-vessel disease (CSVD) is an extensive cerebrovascular disease that mainly involves the perforating arterioles, capillaries and venules and plays a crucial role in stroke and dementia.1 Due to the inability of conventional noninvasive angiography to display small cerebral vessels, relevant brain parenchymal lesions on brain magnetic resonance imaging (MRI) can be used as an alternative marker for CSVD. These markers include recent small subcortical infarcts, lacunes of presumed vascular origin, white matter hyperintensity (WMH) of presumed vascular origin, perivascular space (PVS), cerebral microbleeds (CMBs)...
Source: Journal of Stroke and Cerebrovascular Diseases - August 15, 2020 Category: Neurology Authors: Tiantian Liu, Yuanyuan Liu, Shuhua Wang, Xiaolong Du, Zhaofeng Zheng, Ning Wang, Xunyao Hou, Chao Shen, Jian Chen, Xueping Liu Source Type: research

Correlation Between Intracranial Arterial Calcification and Imaging of Cerebral Small Vessel Disease
Conclusion: Intracranial artery calcification is common in patients with ischemic cerebrovascular disease and the intracranial carotid artery is most frequently affected. Intracranial arterial calcifications might be associated with imaging markers of SVD and are highly correlated with WMHs, lacunes, and CMBs. Quantification of calcification on CT provides additional information on the pathophysiology of SVD. Intracranial arterial calcification could act as a potential marker of SVD. Introduction Atherosclerosis is a systemic vascular process that is considered a major cause of cerebrovascular and cardiovascular di...
Source: Frontiers in Neurology - April 30, 2019 Category: Neurology Source Type: research

Consecutive Slides on Axial View Is More Effective Than Transversal Diameter to Differentiate Mechanisms of Single Subcortical Infarctions in the Lenticulostriate Artery Territory
Conclusion: Consecutive slides on axial view (≥4 consecutive slices) might be more effective than transversal diameter to identify the atherosclerotic mechanisms of SSIs in the lenticulostriate artery territory. Clinical Trial Registration: http://www.clinicaltrials.gov. Unique identifier: NCT00664846 Introduction Single subcortical infarctions (SSIs) have been considered to be caused by lipohyalinosis degeneration in small artery disease, traditionally called lacunar infarct (1). However, atherosclerosis occurring in the parental artery blocking the orifice of the branch artery or atherosclerosis in the p...
Source: Frontiers in Neurology - April 8, 2019 Category: Neurology Source Type: research

Neurological Involvement in Primary Systemic Vasculitis
Conclusion Neurological involvement is a common complication of PSV (Table 1), and neurologists play an important role in the identification and diagnosis of PSV patients with otherwise unexplained neurological symptoms as their chief complaint. This article summarizes the neurological manifestations of PSV and hopes to improve neuroscientists' understanding of this broad range of diseases. TABLE 1 Table 1. Common CNS and PNS involvements of primary systemic vasculitis. Author Contributions SZ conceived the article and wrote the manuscript. DY and GT reviewed and edited the manuscript. All authors ...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

Mediators of the Age Effect among Patients Treated with Carotid Artery Stenting: The Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST) (P02.017)
CONCLUSIONS: These data suggest that a longer carotid artery lesion length is a significant contributor to the increased risk of CAS in the elderly. However, attenuation of the age effect was modest, less than a 10% change in the hazard ratios. Other potential mediators such as tortuosity and atherosclerosis of the aortic arch and great vessels were not assessed. Non-anatomic factors that are more common with advancing age such as cerebral white matter disease and subclinical dementia were also not assessed and may play a role in how elderly patients respond to ischemic insults.Disclosure: Dr. Voeks has nothing to disclose...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Voeks, J., Farb, R., Heck, D., Roubin, G., Moore, W., Logan, W., Longbottom, M., Howard, G., Brott, T. Tags: P02 Cerebrovascular Disease II Source Type: research

Partial eNOS deficiency causes spontaneous thrombotic cerebral infarction, amyloid angiopathy and cognitive impairment
Conclusions: These data provide for the first time the evidence that partial eNOS deficiency results in spontaneous thrombotic cerebral infarctions that increase with age, leading to progressive CAA and cognitive impairments. We thus conclude that eNOS +/- mouse may represent an ideal model of ischemic stroke to address early and progressive damage in spontaneously-evolving chronic cerebral ischemia and thus, study vascular mechanisms contributing to vascular dementia and AD.
Source: Molecular Neurodegeneration - June 24, 2015 Category: Neurology Authors: Xing-Lin TanYue-Qiang XueTao MaXiaofang WangJing LiLubin LanKafait MalikMichael McDonaldAlejandro DopicoFrancesca-Fang Liao Source Type: research

Value of vessel wall magnetic resonance imaging in the diagnosis and management of cerebrovascular diseases
ConclusionIntracranial vessel wall MR imaging is an adjunct to conventional angiographic imaging
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research

Prevalence of Cerebrovascular Events in Extraluminal Protruding Intracranial Atherosclerotic Plaques: Analysis of Intracranial Vessels from the Nun Study (P03.009)
CONCLUSIONS: Outside protruding plaques without angiographic stenosis appear to be responsible for ischemic events in patients with cryptogenic stroke. Higher prevalence of stroke in these patients warrants the use of newer imaging modalities like high resolution magnetic resonance imaging to identify patients who are at high risk of cerebrovascular events.Disclosure: Dr. Semaan has nothing to disclose. Dr. Majidi has nothing to disclose. Dr. Chaudhry has nothing to disclose. Dr. Santa Cruz has nothing to disclose. Dr. Suri has nothing to disclose. Dr. ATACH Investigators has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Semaan, E., Majidi, S., Chaudhry, S., Santa Cruz, K., Suri, M. F., Qureshi, A. Tags: P03 Child Neurology II Source Type: research

Healing through music
The last time I had a mammogram, I got a big surprise — and it was a good one. A string quartet was playing just outside the doors of the breast imaging center, and my thoughts immediately shifted from “What are they going to find on the mammogram?” to “Is that Schubert, or Beethoven?” By the time my name was called, I had almost forgotten why I was there. The unexpected concert was the work of Holly Chartrand and Lorrie Kubicek, music therapists and co-coordinators of the Environmental Music Program at Massachusetts General Hospital. But bringing music to hospital corridors is just a sideline for music therapist...
Source: New Harvard Health Information - November 5, 2015 Category: Consumer Health News Authors: Beverly Merz Tags: Behavioral Health Mental Health Pain Management Surgery Source Type: news