Healing through music

The last time I had a mammogram, I got a big surprise — and it was a good one. A string quartet was playing just outside the doors of the breast imaging center, and my thoughts immediately shifted from “What are they going to find on the mammogram?” to “Is that Schubert, or Beethoven?” By the time my name was called, I had almost forgotten why I was there. The unexpected concert was the work of Holly Chartrand and Lorrie Kubicek, music therapists and co-coordinators of the Environmental Music Program at Massachusetts General Hospital. But bringing music to hospital corridors is just a sideline for music therapists. The majority of their time is spent using music to help patients accomplish specific goals, like recovering their speech after a stroke or reducing the stress of chemotherapy. Chartrand is a vocalist and graduate of Berklee College of Music. She decided to become a music therapist when she realized that she could use music to support others just as it had supported her throughout her life. “The favorite part of my job is seeing how big an impact music can have on someone who isn’t feeling well,” she says. What is music therapy? Music therapy is a burgeoning field. Those who become certified music therapists are accomplished musicians who have deep knowledge of how music can evoke emotional responses to relax or stimulate people, or help them heal. They combine this knowledge with their familiarity with a wide variety ...
Source: New Harvard Health Information - Category: Consumer Health News Authors: Tags: Behavioral Health Mental Health Pain Management Surgery Source Type: news

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In this study, we used three different tasks across domains of function (emotion processing, reward anticipation, and cognitive control, plus resting state connectivity completed prior to start of medication to predict treatment response in 13–36 adults with MDD. For each experiment, adults with MDD were prescribed only label duloxetine (all experiments), whereas another subset were prescribed escitalopram. We used a KeyNet (both Task derived masks and Key intrinsic Network derived masks) approach to targeting brain systems in a specific match to tasks. The most robust predictors were (Dichter et al., 2010) positive ...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - Category: Psychiatry Source Type: research
Publication date: Available online 17 July 2018Source: Progress in Neuro-Psychopharmacology and Biological PsychiatryAuthor(s): Jun Ju, Luping Liu, Yujie Zhang, Qiang ZhouAbstractIn humans, schizophrenia with onset in adolescence or adult has distinct features. To understand whether schizophrenia with either adolescence- or adult-onset have distinct phenotypes and cellular mechanisms in schizophrenia model mice, we altered Nrg1 signaling during either adolescence or adult mice via injection of anti-Nrg1 antibodies. We found that in either early-onset schizophrenia (EOS)- or late-onset schizophrenia (LOS)-like mice, certain...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - Category: Psychiatry Source Type: research
Publication date: Available online 17 July 2018Source: Psychiatric Clinics of North AmericaAuthor(s): Charles R. Conway, Willa Xiong
Source: Psychiatric Clinics of North America - Category: Psychiatry Source Type: research
Publication date: Available online 17 July 2018Source: Psychiatric Clinics of North AmericaAuthor(s): Alexander McGirr, Marcelo T. Berlim
Source: Psychiatric Clinics of North America - Category: Psychiatry Source Type: research
ConclusionsFluoxetine and GCBT are similarly effective initial treatments for childhood OCD considering treatment failures over time. Consequently, provision of treatment for childhood OCD could be tailored according to the availability of local resources.
Source: Journal of Anxiety Disorders - Category: Psychiatry Source Type: research
This study provides initial support for use of CBT-based bibliotherapy plus doll in the treatment of nighttime fears. Such a treatment might be used to supplement standard CBT approaches in routine clinical practice or in a stepped care approach to treatment.
Source: Journal of Anxiety Disorders - Category: Psychiatry Source Type: research
This study provides evidence about the deterioration rates of a therapeutic VR approach, showing that the number of deteriorated patients coincides with other therapeutic approaches, and that deterioration is less likely to occur, compared to patients in WL control groups.
Source: Journal of Anxiety Disorders - Category: Psychiatry Source Type: research
Publication date: 17 July 2018Source: Cell Reports, Volume 24, Issue 3Author(s): Alice H. Hsu, Michelle A. Lum, Kang-Sup Shim, Peter J. Frederick, Carl D. Morrison, Baojiang Chen, Subodh M. Lele, Yuri M. Sheinin, Takiko Daikoku, Sudhansu K. Dey, Gustavo Leone, Adrian R. Black, Jennifer D. BlackSummaryProtein kinase C (PKC) isozymes are commonly recognized as oncoproteins based on their activation by tumor-promoting phorbol esters. However, accumulating evidence indicates that PKCs can be inhibitory in some cancers, with recent findings propelling a shift in focus to understanding tumor suppressive functions of these enzyme...
Source: Cell Reports - Category: Cytology Source Type: research
Publication date: 17 July 2018Source: Cell Reports, Volume 24, Issue 3Author(s): James Monypenny, Hanna Milewicz, Fabian Flores-Borja, Gregory Weitsman, Anthony Cheung, Ruhe Chowdhury, Thomas Burgoyne, Appitha Arulappu, Katherine Lawler, Paul R. Barber, Jose M. Vicencio, Melanie Keppler, Wahyu Wulaningsih, Sean M. Davidson, Franca Fraternali, Natalie Woodman, Mark Turmaine, Cheryl Gillett, Dafne Franz, Sergio A. QuezadaSummaryThe immunosuppressive transmembrane protein PD-L1 was shown to traffic via the multivesicular body (MVB) and to be released on exosomes. A high-content siRNA screen identified the endosomal sorting co...
Source: Cell Reports - Category: Cytology Source Type: research
Publication date: 17 July 2018Source: Cell Reports, Volume 24, Issue 3Author(s): Mayura V. Wagle, Julia M. Marchingo, Jason Howitt, Seong-Seng Tan, Christopher C. Goodnow, Ian A. ParishSummaryEscape from peripheral tolerance checkpoints that control cytotoxic CD8+ T cells is important for cancer immunotherapy and autoimmunity, but pathways enforcing these checkpoints are mostly uncharted. We reveal that the HECT-type ubiquitin ligase activator, NDFIP1, enforces a cell-intrinsic CD8+ T cell checkpoint that desensitizes TCR signaling during in vivo exposure to high antigen levels. Ndfip1-deficient OT-I CD8+ T&...
Source: Cell Reports - Category: Cytology Source Type: research
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