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Specialty: Rheumatology
Condition: Arthritis

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Total 260 results found since Jan 2013.

How hand osteoarthritis, comorbidity and pain interact to determine functional limitation in older people: Observations from the eposa study
Conclusions. Study results have demonstrated that although comorbidity was decidedly and independently associated with hand functional limitation, it has no effect on the hand OA‐physical function relationship. Hand OA was found to be associated with self‐reported as well as with performance‐based physical function impairment; the association was found to be partially mediated by pain, which reduces its impact. This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatism - May 22, 2016 Category: Rheumatology Authors: Paola Siviero, Sabina Zambon, Federica Limongi, Maria Victoria Castell, Cyrus Cooper, Dorly J.H. Deeg, Michael D. Denkinger, Elaine M. Dennison, Mark H. Edwards, Antonella Gesmundo, Ángel Otero, Nancy L. Pedersen, Richard Peter, Rocio Queipo, Erik J. Tim Tags: Full Length Source Type: research

Rheumatoid Factors Are Associated with Subclinical and Clinical Atherosclerosis in African American Women: The Multi‐Ethnic Study of Atherosclerosis (MESA)
Conclusion. RA‐related autoantibodies are associated with subclinical and clinical atherosclerosis in AA women from a community based non‐RA cohort indicating autoimmune factors may play a role in the pathogenesis of atherosclerosis. This article is protected by copyright. All rights reserved.
Source: Arthritis Care and Research - May 8, 2016 Category: Rheumatology Authors: Darcy S. Majka, Thanh‐Huyen T. Vu, Richard M. Pope, Marius Teodorescu, Elizabeth W. Karlson, Kiang Liu, Rowland W. Chang Tags: Original Article Source Type: research

Association of Osteoarthritis With Increased Risk of Cardiovascular Diseases in the Elderly: Findings From the Progetto Veneto Anziano Study Cohort
ConclusionOA may be a significant predictor of the onset of CVD in elderly individuals, particularly in women with OA and when OA affects the lower limbs or ≥2 joints are involved.
Source: Arthritis and Rheumatism - April 26, 2016 Category: Rheumatology Authors: Nicola Veronese, Caterina Trevisan, Marina De Rui, Francesco Bolzetta, Stefania Maggi, Sabina Zambon, Estella Musacchio, Leonardo Sartori, Egle Perissinotto, Gaetano Crepaldi, Enzo Manzato, Giuseppe Sergi Tags: Osteoarthritis Source Type: research

Risk of Cerebrovascular Accidents and Ischemic Heart Disease in Cutaneous Lupus Erythematosus: A Population‐based Cohort Study
Conclusion: CLE may be associated with an increased risk of CVA and PAD, but not IHD. Factors contributing to increase CVA risk in patients with CLE merit evaluation. This article is protected by copyright. All rights reserved.
Source: Arthritis Care and Research - March 24, 2016 Category: Rheumatology Authors: Abha G. Singh, Cynthia S. Crowson, Siddharth Singh, Mark Denis P. Davis, Hilal Maradit‐Kremers, Eric L. Matteson, Vaidehi R. Chowdhary Tags: Original Article Source Type: research

Does renin‐angiotensin system blockade protect lupus nephritis patients from atherosclerotic cardiovascular events? A case‐control study
Conclusions: Our data do not support the hypothesis that ACEIs/ARBs may be protective against atherosclerotic CVEs in LN patients. This article is protected by copyright. All rights reserved.
Source: Arthritis Care and Research - February 11, 2016 Category: Rheumatology Authors: Konstantinos Tselios, Dafna D Gladman, Jiandong Su, Murray B Urowitz Tags: Original Article Source Type: research

A polyarticular onset and diabetes could be the main predictors of cardiovascular events in psoriatic arthritis.
CONCLUSIONS: Traditional CV risk factors as well as factors related to the inflammatory nature of the disease were the main predictors of CV complications in this PsA population. PMID: 26841682 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - February 6, 2016 Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research

What to expect when expecting with SLE: A population‐based study of maternal and fetal outcomes in SLE and pre‐SLE
Conclusions: Our data demonstrate that adverse maternal and fetal outcomes are more common in SLE pregnancies. Furthermore these unfavourable outcomes are observed in pregnancies occurring prior to the diagnosis of SLE. Thus, the underlying immunologic profile of SLE and alterations preceding clinical SLE may contribute to these pregnancy complications. This article is protected by copyright. All rights reserved.
Source: Arthritis Care and Research - February 1, 2016 Category: Rheumatology Authors: Elizabeth V. Arkema, Kristin Palmsten, Christopher Sjöwall, Elisabet Svenungsson, Jane E. Salmon, Julia F. Simard Tags: Original Article Source Type: research

Clinical Image: Mitral Valve Vegetation in Antiphospholipid Syndrome
This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatism - January 27, 2016 Category: Rheumatology Authors: Ozan Unlu, Sarah B. Lieber, Mary J. Roman, Doruk Erkan, Michael D. Lockshin Tags: Clinical Image Source Type: research

Association of hyperlipidaemia, inflammation and serological status and coronary heart disease among patients with rheumatoid arthritis: data from the National Veterans Health Administration
Conclusions In this predominantly older male RA cohort, there was no clear association between LDL-C and CHD, whereas higher HDL-C was inversely associated with MI and stroke. CRP and ESR were similarly associated with increase MI risk and stroke, reflecting the prominent role of inflammation in CHD risk in RA.
Source: Annals of the Rheumatic Diseases - January 11, 2016 Category: Rheumatology Authors: Navarro-Millan, I., Yang, S., DuVall, S. L., Chen, L., Baddley, J., Cannon, G. W., Delzell, E. S., Zhang, J., Safford, M. M., Patkar, N. M., Mikuls, T. R., Singh, J. A., Curtis, J. R. Tags: Open access, Immunology (including allergy), Inflammation, Connective tissue disease, Degenerative joint disease, Musculoskeletal syndromes, Rheumatoid arthritis Clinical and epidemiological research Source Type: research

Association between ischaemic stroke and tumour necrosis factor inhibitor therapy in patients with rheumatoid arthritis
Conclusions: Exposure to TNFi does not appear to influence the occurrence of IS in the medium term in patients with RA. The impact on post‐IS mortality remains inconclusive. This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatism - January 8, 2016 Category: Rheumatology Authors: Audrey S.L. Low, Mark Lunt, Louise K. Mercer, Kath D. Watson, William G. Dixon, Deborah P.M. Symmons, Kimme L. Hyrich Tags: Full Length Source Type: research

The impact of inflammatory rheumatic diseases on the presentation, severity, and outcome of acute coronary syndrome
Abstract Patients with inflammatory rheumatic diseases (IRD) have a high burden of cardiovascular disease (CVD), leading to increased mortality and morbidity. However, it is not clear whether increased CVD mortality in IRD is due to a higher incidence or worse outcome of cardiovascular events (higher case fatality). In this observational case–control study, we assessed the outcome of acute coronary syndrome (ACS) in patients with IRDs compared to matched controls without IRD, using data from the Acute Coronary Syndrome Israeli Survey (ACSIS), a large, national, real-life registry detailing the extent, severity,...
Source: Clinical Rheumatology - January 1, 2016 Category: Rheumatology Source Type: research

Osteoarthritis increases the risk of cardiovascular diseases in the elderly: The progetto veneto anziano study
Conclusions: OA significantly predicted the onset of CVD in elderly people, particularly when it involved lower limbs, women, and more than two joints. This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatism - December 29, 2015 Category: Rheumatology Authors: Nicola Veronese, Caterina Trevisan, Marina De Rui, Francesco Bolzetta, Stefania Maggi, Sabina Zambon, Estella Musacchio, Leonardo Sartori, Egle Perissinotto, Gaetano Crepaldi, Enzo Manzato, Giuseppe Sergi Tags: Full Length Source Type: research

Arthritis Research UK joins the Richmond Group of Charities
We're delighted to announce that we've become a member of the Richmond Group of Charities. The Richmond Group (which includes other health charities including Macmillan Cancer Support, Age UK, British Heart Foundation and the Stroke Association) works as a collective voice to influence health and social care policy, with the aim of improving care and support for the 15 million people living with long-term conditions. We'll also be joining the group alongside long-term conditions charity the Alzheimer’s Society. We've been working in partnership with the Richmond Group over the last year on its ‘Doing the Righ...
Source: Arthritis Research UK - December 17, 2015 Category: Rheumatology Source Type: news

The burden of co‐morbidity in Systemic Lupus Erythematosus in the United Kingdom 1999‐2012
Conclusions: People with SLE in the UK have a greater burden of co‐morbidity and are more likely to develop CVD, stroke, ESRF, cancer, osteoporosis and infection than people of the same age and gender. This article is protected by copyright. All rights reserved.
Source: Arthritis Care and Research - October 16, 2015 Category: Rheumatology Authors: Frances Rees, Michael Doherty, Matthew Grainge, Peter Lanyon, Graham Davenport, Weiya Zhang Tags: Original Article Source Type: research

Osteoarthritis, comorbidity and pain: Their role in determining functional limitations in older populations (European project on Osteoarthritis)
Conclusions: These findings demonstrate that while comorbidity is strongly and independently associated to functional limitations, it does not affect the OA‐physical function association. Hip/knee OA is associated to self‐reported impairment in physical function, which was only partially mediated by pain. Its association to physical function, as evaluated by the walking test, was, instead, completely mediated by pain. This article is protected by copyright. All rights reserved.
Source: Arthritis Care and Research - October 16, 2015 Category: Rheumatology Authors: Sabina Zambon, Paola Siviero, Michael Denkinger, Federica Limongi, Maria Victoria Castell, Suzan van der Pas, Ángel Otero, Mark H Edwards, Richard Peter, Nancy L Pedersen, Mercedes Sánchez‐Martinez, Elaine M Dennison, Antonella Gesmundo, Laura A Schaa Tags: Original Article Source Type: research