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Specialty: Rheumatology
Condition: Arthritis

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Total 260 results found since Jan 2013.

Herpes Zoster and the Risk for Stroke in Patients with Autoimmune Diseases
Conclusion: In patients with autoimmune diseases, incident HZ was associated with up to a two‐fold increased risk for stroke in the subsequent few months. These data provide urgency for developing strategies to reduce the risk of VZV. This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatism - September 1, 2016 Category: Rheumatology Authors: L.H. Calabrese, F. Xie, H. Yun, K. Winthrop, J.W. Baddley, C. Calabrese, J.R. Curtis Tags: Full Length Source Type: research

Rivaroxaban 'could be a safe treatment option for antiphospholipid syndrome'
The drug rivaroxaban could be an effective means of treating some patients with thromboticantiphospholipid syndrome, according to a new study. Led by University College London and funded byArthritis Research UK, the research has suggested that the drug - which works by inhibiting the formation of blood clots - could be a useful tool in the treatment of those with this serious condition, which affects approximately 15 per cent of patients withlupus and may also occur on its own. The danger of antiphospholipid syndrome Thrombotic antiphospholipid syndrome is classified as a rare condition, but is probably underdiagnosed. It ...
Source: Arthritis Research UK - August 29, 2016 Category: Rheumatology Source Type: news

Comorbidities in patients with Primary Sj ögren's Syndrome and Systemic Lupus Erythematosus: A comparative registries‐based study
Conclusions: pSS patients have consistently less serious CV comorbidity burden and a lower prevalence of severe infection than those with SLE. In contrast, their risk of lymphoma was greater. This article is protected by copyright. All rights reserved.
Source: Arthritis Care and Research - August 25, 2016 Category: Rheumatology Authors: I ñigo Rúa‐Figueroa, Mónica Fernández de Castro, José L. Andreu, Carlos Sanchez‐Piedra, Víctor Martínez‐Taboada, Alejandro Olivé, Javier López‐Longo, José Rosas, María Galindo, Jaime Calvo‐Alén, Antonio Fernández‐Nebro, Fernando A Tags: Original Article Source Type: research

Does Renin ‐Angiotensin System Blockade Protect Lupus Nephritis Patients From Atherosclerotic Cardiovascular Events? A Case–Control Study
ConclusionOur data do not support the hypothesis that ACE inhibitors/ARBs may be protective against atherosclerotic CVEs in LN patients.
Source: Arthritis Care and Research - August 18, 2016 Category: Rheumatology Authors: Konstantinos Tselios, Dafna D. Gladman, Jiandong Su, Murray B. Urowitz Tags: Original Article Source Type: research

Incidence and predictors for cardiovascular events in patients with psoriatic arthritis
Conclusion A significant proportion of patients with PsA develop cardiovascular events during the course of their disease. Increased cardiovascular risk is associated with a combination of traditional cardiovascular risk factors and disease activity.
Source: Annals of the Rheumatic Diseases - August 9, 2016 Category: Rheumatology Authors: Eder, L., Wu, Y., Chandran, V., Cook, R., Gladman, D. D. Tags: Degenerative joint disease, Musculoskeletal syndromes Clinical and epidemiological research Source Type: research

Patterns and consequences of multimorbidity in the general population: There is no chronic disease management without rheumatic disease management
Conclusion: Our study emphasizes RMDs as a major presence in multimorbidity in the general population. All multimorbidity patterns were associated with a wide set of adverse health outcomes. Management strategies for the patient with chronic cardiometabolic, respiratory or depressive conditions should also target RMDs. This article is protected by copyright. All rights reserved.
Source: Arthritis Care and Research - August 1, 2016 Category: Rheumatology Authors: Daniela Sim ões, Fábio A. Araújo, Milton Severo, Teresa Monjardino, Ivo Cruz, Loreto Carmona, Raquel Lucas Tags: Original Article Source Type: research

Fatigue in rheumatoid arthritis 'may need to be treated separately'
This study highlights the need for better treatments for fatigue, which can be used alongside existing medication. We need to ensure fatigue has recognition from medical professionals so people can get the care they require."Along with pain, fatigue is one of the things that people with arthritis tell us has the biggest impact on their lives, which is why Arthritis Research UK is funding research into coping with the effects of fatigue on a day-to-day basis."
Source: Arthritis Research UK - June 23, 2016 Category: Rheumatology Source Type: news

What to Expect When Expecting With Systemic Lupus Erythematosus (SLE): A Population‐Based Study of Maternal and Fetal Outcomes in SLE and Pre‐SLE
ConclusionOur data demonstrate that adverse maternal and fetal outcomes are more common in SLE pregnancies. Furthermore, these unfavorable outcomes are observed in pregnancies occurring prior to the diagnosis of SLE. Thus, the underlying immunologic profile of SLE and alterations preceding clinical SLE may contribute to these pregnancy complications.
Source: Arthritis Care and Research - June 22, 2016 Category: Rheumatology Authors: Elizabeth V. Arkema, Kristin Palmsten, Christopher Sjöwall, Elisabet Svenungsson, Jane E. Salmon, Julia F. Simard Tags: Systemic Lupus Erythematosus Source Type: research

What to Expect When Expecting With Systemic Lupus Erythematosus (SLE): A Population ‐Based Study of Maternal and Fetal Outcomes in SLE and Pre‐SLE
ConclusionOur data demonstrate that adverse maternal and fetal outcomes are more common in SLE pregnancies. Furthermore, these unfavorable outcomes are observed in pregnancies occurring prior to the diagnosis of SLE. Thus, the underlying immunologic profile of SLE and alterations preceding clinical SLE may contribute to these pregnancy complications.
Source: Arthritis Care and Research - June 22, 2016 Category: Rheumatology Authors: Elizabeth V. Arkema, Kristin Palmsten, Christopher Sj öwall, Elisabet Svenungsson, Jane E. Salmon, Julia F. Simard Tags: Systemic Lupus Erythematosus Source Type: research

Trends in Hospitalizations Due to Acute Coronary Syndromes and Stroke in Patients with Systemic Lupus Erythematosus, 1996 To 2012
Conclusion: Increased awareness of the burden of CVD in patients with SLE has not yet translated into decreases in hospitalizations for acute myocardial infarction or stroke. This may be due to barriers in implementation of CVD risk factor modification, or SLE‐specific risks that have not yet been identified or effectively targeted. This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatism - June 5, 2016 Category: Rheumatology Authors: Maria G. Tektonidou, Zhong Wang, Michael M. Ward Tags: Brief Report Source Type: research

Lupus patients 'at higher risk of developing other health conditions'
People with lupus are at a greater risk of developing other health conditions than members of the general population.This is according to a new study conducted by the University of Nottingham and the Arthritis Research UK Primary Care Centre at Keele University, which examined the frequency of comorbidities associated with systemic lupus erythematosus in the UK between 1999 and 2012.A broad UK study Published in the medical journal Arthritis Care & Research, the study drew upon data from the UK Clinical Practice Research Datalink, identifying cases of lupus and matching each one by age, gender and practice to four heal...
Source: Arthritis Research UK - May 26, 2016 Category: Rheumatology Source Type: news

Association Between Ischemic Stroke and Tumor Necrosis Factor Inhibitor Therapy in Patients With Rheumatoid Arthritis
ConclusionExposure to TNFi does not appear to influence the occurrence of ischemic stroke in the medium term in patients with RA. The impact on mortality after ischemic stroke remains inconclusive.
Source: Arthritis and Rheumatism - May 25, 2016 Category: Rheumatology Authors: Audrey S. L. Low, Mark Lunt, Louise K. Mercer, Kath D. Watson, William G. Dixon, Deborah P. M. Symmons, Kimme L. Hyrich Tags: Rheumatoid Arthritis Source Type: research

Role of Osteoarthritis, Comorbidity, and Pain in Determining Functional Limitations in Older Populations: European Project on Osteoarthritis
ConclusionThese findings demonstrate that while comorbidity is strongly and independently associated with functional limitations, it does not affect the OA–physical function association. Hip/knee OA is associated with self‐reported impairment in physical function, which was only partially mediated by pain. Its association with physical function, as evaluated by the walking test, was instead completely mediated by pain.
Source: Arthritis Care and Research - May 25, 2016 Category: Rheumatology Authors: Sabina Zambon, Paola Siviero, Michael Denkinger, Federica Limongi, Maria Victoria Castell, Suzan van der Pas, Ángel Otero, Mark H. Edwards, Richard Peter, Nancy L. Pedersen, Mercedes Sánchez‐Martinez, Elaine M. Dennison, Antonella Gesmundo, Laura A. S Tags: Osteoarthritis Source Type: research

Burden of Comorbidity in Systemic Lupus Erythematosus in the UK, 1999–2012
ConclusionPeople with SLE in the UK have a greater burden of comorbidity and are more likely to develop CVD, stroke, ESRF, cancer, osteoporosis, and infection than people of the same age and sex.
Source: Arthritis Care and Research - May 25, 2016 Category: Rheumatology Authors: Frances Rees, Michael Doherty, Matthew Grainge, Peter Lanyon, Graham Davenport, Weiya Zhang Tags: Systemic Lupus Erythematosus Source Type: research

Risk of Myocardial Infarction and Stroke in Patients with Granulomatosis with Polyangiitis: A Population‐Based Study
Conclusion: GPA patients have a significantly increased risk of MI, with a non‐statistically significant trend towards increased risk of ischemic stroke. Monitoring for this complication and vigilance in modifying risk factors is particularly warranted in this patient population, especially early after diagnosis. This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatism - May 22, 2016 Category: Rheumatology Authors: J. Antonio Aviña‐Zubieta, Alice Mai, Neda Amiri, Natasha Dehghan, Ju Ann Tan, Eric C. Sayre, Hyon K. Choi Tags: Full Length Source Type: research