Lupus patients 'at higher risk of developing other health conditions'

People with lupus are at a greater risk of developing other health conditions than members of the general population.This is according to a new study conducted by the University of Nottingham and the Arthritis Research UK Primary Care Centre at Keele University, which examined the frequency of comorbidities associated with systemic lupus erythematosus in the UK between 1999 and 2012.A broad UK study Published in the medical journal Arthritis Care &Research, the study drew upon data from the UK Clinical Practice Research Datalink, identifying cases of lupus and matching each one by age, gender and practice to four healthy subjects.They measured the incidence of cardiovascular disease, stroke, end-stage renal failure, cancer, osteoporosis and infection between the two groups, taking into account potentially influential factors such as age, gender, body mass index, smoking status, alcohol intake, hypertension, hyperlipidaemia and use of the drug prednisolone.In total, 7,732 prevalent cases of lupus were identified and compared to 28,079 matched controls.A greater risk for lupus patients It was found that people with lupus were more likely to suffer from heart disease, stroke, renal failure, cancer, osteoporosis and infections than those without lupus.Broken down in terms of gender, men with lupus were shown to have higher rates of cardiovascular disease, stroke and cancer, whereas women had higher rates of infection and osteoporosis. Those at younger ages were at the greates...
Source: Arthritis Research UK - Category: Rheumatology Source Type: news

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Publication date: Available online 8 April 2020Source: Journal of Solid State ChemistryAuthor(s): Xiaodong Wang, Yanjun Yin, Mingling Li, Yuan Hu
Source: Journal of Solid State Chemistry - Category: Chemistry Source Type: research
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Yangjie Xu, Jiulong Zhao, Zhilun Zhang, Jing Zhang, Mingxian Huang, Shige Wang, Pei Xie To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Soft Matter latest articles - Category: Chemistry Authors: Source Type: research
Lab Chip, 2020, Advance Article DOI: 10.1039/C9LC00811J, PaperA. D. Rodriguez, L. F. Horowitz, K. Castro, H. Kenerson, N. Bhattacharjee, G. Gandhe, A. Raman, R. J. Monnat, R. Yeung, R. C. Rostomily, A. Folch We have developed a digitally-manufacturable microfluidic platform that allows for multiplexed drug testing of intact tumor slices. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Lab Chip latest articles - Category: Chemistry Authors: Source Type: research
Dalton Trans., 2020, Advance Article DOI: 10.1039/D0DT00473A, PaperSongyang Huang, Jianbin Wu, Jiale Li, Lirong Yu, Xi Wang, Ming Bai It is found for the first time that TPEBA-modified PVA ligand-coated lanthanide nanoparticles display tunable luminescent properties due to the established energy transfer from the TPE-based ligand (donor) to the lanthanide nanoparticles (acceptor). To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Dalton Trans. latest articles - Category: Chemistry Authors: Source Type: research
Conclusions: Treatment outcome of PRCA depended upon the causes and the types of treatment, and the burden of RBC transfusion was very high in patients with ESA and thymoma-associated PRCA. PMID: 32257434 [PubMed]
Source: Anemia - Category: Hematology Tags: Anemia Source Type: research
Authors: Park CH, Yang DH, Kim JW, Kim JH, Kim JH, Min YW, Lee SH, Bae JH, Chung H, Choi KD, Park JC, Lee H, Kwak MS, Kim B, Lee HJ, Lee HS, Choi M, Park DA, Lee JY, Byeon JS, Park CG, Cho JY, Lee ST, Chun HJ Abstract Although surgery was the standard treatment for early gastrointestinal cancers, endoscopic resection is now a standard treatment for early gastrointestinal cancers without regional lymph node metastasis. High-definition white light endoscopy, chromoendoscopy, and image-enhanced endoscopy such as narrow band imaging are performed to assess the edge and depth of early gastrointestinal cancers for deline...
Source: Clinical Endoscopy - Category: Gastroenterology Tags: Clin Endosc Source Type: research
Authors: Abadir AP, Ali MF, Karnes W, Samarasena JB Abstract Artificial intelligence (AI) is rapidly integrating into modern technology and clinical practice. Although in its nascency, AI has become a hot topic of investigation for applications in clinical practice. Multiple fields of medicine have embraced the possibility of a future with AI assisting in diagnosis and pathology applications. In the field of gastroenterology, AI has been studied as a tool to assist in risk stratification, diagnosis, and pathologic identification. Specifically, AI has become of great interest in endoscopy as a technology with substa...
Source: Clinical Endoscopy - Category: Gastroenterology Tags: Clin Endosc Source Type: research
Authors: Yoon HJ, Kim JH Abstract Diagnosis and evaluation of early gastric cancer (EGC) using endoscopic images is significantly important; however, it has some limitations. In several studies, the application of convolutional neural network (CNN) greatly enhanced the effectiveness of endoscopy. To maximize clinical usefulness, it is important to determine the optimal method of applying CNN for each organ and disease. Lesion´┐Ż-based CNN is a type of deep learning model designed to learn the entire lesion from endoscopic images. This review describes the application of lesion-based CNN technology in diagnosis of E...
Source: Clinical Endoscopy - Category: Gastroenterology Tags: Clin Endosc Source Type: research
Authors: Liu Y, Cai Y, Chen S, Gou Y, Wang Q, Zhang M, Wang Y, Hong H, Zhang K Abstract Secondary prevention is an important strategy in gastric cancer. Low-grade intraepithelial neoplasia (LGIN) is the last stage of precancerous lesion, and its timely diagnosis can greatly improve the detection rate of early gastric cancer. We performed a prospective study to analyze the risk factors of gastric LGIN in asymptomatic subjects undergoing physical examination. A total of 3437 subjects were included in this study, and 2259 asymptomatic subjects were investigated from March 2015 to April 2018. Risk factors were evaluate...
Source: Gastroenterology Research and Practice - Category: Gastroenterology Tags: Gastroenterol Res Pract Source Type: research
Conclusions: The combined use of the QuantiFERON-TB test and multiple indexes can significantly improve the accuracy of diagnosing tuberculous peritonitis. PMID: 32256565 [PubMed]
Source: Gastroenterology Research and Practice - Category: Gastroenterology Tags: Gastroenterol Res Pract Source Type: research
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