What Are Some Indications for Using Dexamethasone?
Discussion Corticosteroids are a group of drugs which can be naturally or synthetically produced. Naturally occurring substances are produced in the adrenal gland, and are protein-bound (primarily corticosteroid-binding globulin and albumin). In the target tissues, they may need to be converted to an active substance. They are then reduced, oxidized, hydroxylated or conjugated as measures to inactivate them. Synthetic steroids have less protein binding and depending on their structure are more or less resistant to inactivation. Prednisone is the glucocorticoid most often used for treatment, especially as it has a short hal...
Source: PediatricEducation.org - June 7, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

DDMA asks pharmacies to display available stock, cost of COVID-19 drugs prominently
The drugs are Ivermectin tablets, Doxycyclin tablets/capsule, Methyl Prednisolone tablets and injections, Dexamethasone tablets and injections, Budosenide Inhalers and Respules Favipiravir tablets, Apixaban tablets and Enoxaparin Sodium/ Clexane, it said. (Source: The Economic Times)
Source: The Economic Times - May 22, 2021 Category: Consumer Health News Source Type: news

Janssen Provides Update on Phase 3 ACIS Study in Patients with Metastatic Castration-Resistant Prostate Cancer Treated with ERLEADA ® (apalutamide) and ZYTIGA® (abiraterone acetate) Plus Prednisone Combination
RARITAN, N.J., April 19, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that regulatory submissions based on the Phase 3 ACIS study, which evaluated the combination of ERLEADA® (apalutamide) and ZYTIGA® (abiraterone acetate) plus prednisone in patients with chemotherapy-naïve metastatic castration-resistant prostate cancer (mCRPC), will not be pursued. As presented at the American Society of Clinical Oncology’s Genitourinary (ASCO GU) Cancers Symposium in February 2021, the ACIS study met its primary endpoint of radiographic progression-free survival (rPFS); ho...
Source: Johnson and Johnson - April 19, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Janssen Presents Results from Phase 3 ACIS Study in Patients with Metastatic Castration-Resistant Prostate Cancer Treated with ERLEADA ® (apalutamide) and ZYTIGA® (abiraterone acetate) Combination
RARITAN, N.J., February 8, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today results from the randomized, double-blind, placebo-controlled Phase 3 ACIS study, which met the primary endpoint of radiographic progression-free survival (rPFS) with a 31 percent reduction in the risk of radiographic progression or death in patients with chemotherapy-naïve metastatic castration-resistant prostate cancer (mCRPC) receiving androgen deprivation therapy (ADT). Patients in the trial received either a combination of ERLEADA® and ZYTIGA® plus prednisone (combination arm) or placebo a...
Source: Johnson and Johnson - February 8, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Janssen to Highlight Robust Solid Tumor Portfolio and Pipeline at 2021 ASCO GU
February 2, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today it will highlight the depth of its solid tumor portfolio at the American Society of Clinical Oncology Genitourinary (ASCO GU) Cancers Symposium with 12 data presentations, including three company-sponsored oral presentations from the ERLEADA® (apalutamide) clinical development program. The virtual meeting will take place February 11-13, 2021. “We are committed to the development of innovative therapies for patients with genitourinary cancers for whom there remains a high unmet need,” said C...
Source: Johnson and Johnson - February 2, 2021 Category: Pharmaceuticals Tags: Our Company Source Type: news

Serum Prednisolone and Corticosteroid Adherence in Asthma Serum Prednisolone and Corticosteroid Adherence in Asthma
Serum prednisolone measurements may be an effective means of monitoring adherence to oral corticosteroid treatment in severe asthma patients.BMC Pulmonary Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 23, 2020 Category: Consumer Health News Tags: Pulmonary Medicine Journal Article Source Type: news

Roche ’s IPATential150 study evaluating ipatasertib in combination with abiraterone and prednisone/prednisolone met one of its co-primary endpoints
      ·Phase III IPATential150 study evaluating ipatasertib in combination with abiraterone and prednisone/prednisolone compared to current standard-of-care (abiraterone and prednisone/prednisolone alone) plus placebo met its co-primary endpoint of radiographic progression free survival (rPFS) in patients with PTEN loss tumoursBasel, 19 June 2020 – Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the phase III IPATential150 study met its co-primary endpoint of radiographic progression-free survival (rPFS) in patients with metastatic castration-resistant prostate cancer (mCR...
Source: Roche Media News - June 19, 2020 Category: Pharmaceuticals Source Type: news

Roche ’s IPATential150 study evaluating ipatasertib in combination with abiraterone and prednisone/prednisolone met one of its co-primary endpoints
Basel, 19 June 2020 – Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the phase III IPATential150 study met its co-primary endpoint of radiographic progression-free survival (rPFS) in patients with metastatic castration-resistant prostate cancer (mCRPC) and whose tumours had PTEN loss. In this patient group, ipatasertib in combination with abiraterone and prednisone/prednisolone provided a statistically significant reduction in the risk of disease worsening or death, compared to current standard of care (abiraterone and prednisone/prednisolone) plus placebo. The other co-primary endpoint of rPFS in the overal...
Source: Roche Investor Update - June 19, 2020 Category: Pharmaceuticals Source Type: news

Millipred (Prednisolone Tablets) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - April 8, 2020 Category: Drugs & Pharmacology Source Type: news

Featured Review: Reducing uncertainties in choosing first-line treatment in newly diagnosed multiple myeloma
Multiple myeloma is a type of blood cancer. It accounts for approximately 2% of all cancers and is still considered incurable. For people with newly diagnosed multiple myeloma (NDMM), who are unsuitable for a procedure where damaged blood cells are replaced with healthy ones (stem-cell transplant), treatment is usually a multiple drug combination of bortezomib, lenalidomide, or thalidomide, plus melphalan and prednisolone (MP) or dexamethasone (D). Multiple drug combinations are approved for initial anti-myeloma therapy, however, access to these medicines is restricted in many countries worldwide.The Cochrane Review used n...
Source: Cochrane News and Events - November 26, 2019 Category: Information Technology Authors: Katie Abbotts Source Type: news

Commonly prescribed anti-inflammatory 'may increase the risk of diabetes'
Prednisolone was given to a group of men in a study led by Sapienza University of Rome. Their blood sugar regulation was impaired as a result. It could lead to insulin resistance. (Source: the Mail online | Health)
Source: the Mail online | Health - November 12, 2019 Category: Consumer Health News Source Type: news

Low-Dose Prednisolone Reduces Hand Arthritis Pain
No abstract available (Source: Lippincott's Bone and Joint Newsletter)
Source: Lippincott's Bone and Joint Newsletter - September 23, 2019 Category: Orthopaedics Tags: Snapshot Source Type: news

Omnipred (Prednisolone Acetate) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - July 31, 2019 Category: Drugs & Pharmacology Source Type: news

Low-dose prednisolone significantly improves pain symptoms and function in hand osteoarthritis
(European League Against Rheumatism) The results of the low-dose prednisolone in patients with hand osteoarthritis (HOPE) study presented today at the Annual European Congress of Rheumatology (EULAR 2019) show that low-dose prednisolone significantly improves pain and function in patients with painful hand osteoarthritis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 12, 2019 Category: International Medicine & Public Health Source Type: news

What Causes Facial Nerve Palsy?
Discussion Facial nerve palsy has been known for centuries, but in 1821 unilateral facial nerve paralysis was described by Sir Charles Bell. Bell’s palsy (BP) is a unilateral, acute facial paralysis that is clinically diagnosed after other etiologies have been excluded by appropriate history, physical examination and/or laboratory testing or imaging. Symptoms include abnormal movement of facial nerve. It can be associated with changes in facial sensation, hearing, taste or excessive tearing. The right and left sides are equally affected but bilateral BP is rare (0.3%). Paralysis can be complete or incomplete at prese...
Source: PediatricEducation.org - June 3, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Class 4 medicines defect information: prednisolone 5mg tablets
Genus Pharmaceuticals Ltd has informed the MHRA that there is an error on the Braille for certain batches of prednisolone 5mg tablets (PL 42967/0037), where the strength reads as 1mg instead of 5mg. T (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - April 26, 2019 Category: Drugs & Pharmacology Source Type: news

Prednisolone Acetate 1% Ophthalmic Suspension (Updated - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - April 11, 2019 Category: Drugs & Pharmacology Source Type: news

Greater Skills Equals Greater Ability to Combat Leprosy
Dr Ken Jetton (left) and Dr Arturo Cunanan (centre) with a patient who has been cured of leprosy in the Majuro leprosy clinic in the capital of the Marshall Islands. The patient is now seeking further help due to post-treatment complexities. Credit: Stella Paul/IPSBy Stella PaulMAJURO, Apr 4 2019 (IPS) It’s a Friday morning and Dr. Ken Jetton, the only doctor who treats leprosy in Majuro, the capital of the Marshall Islands, is seeing a patient recently cured of the disease. David, 32, has received multidrug therapy (MDT) treatment for a year already. But he is back in the doctor’s office because of a reversal ...
Source: IPS Inter Press Service - Health - April 4, 2019 Category: International Medicine & Public Health Authors: Stella Paul Tags: Asia-Pacific Development & Aid Editors' Choice Featured Headlines Health Human Rights Regional Categories TerraViva United Nations Hansen's disease leprosy Marshall Islands Nippon Foundation Sasakawa Health Foundation Sasakawa Source Type: news

prednisolone (Orapred, Pediapred)
Title: prednisolone (Orapred, Pediapred)Category: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 3/19/2019 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - March 19, 2019 Category: Rheumatology Source Type: news

Doxycycline + prednisolone cost effective in COPD exacerbation?
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - January 1, 2019 Category: Drugs & Pharmacology Source Type: news

Promise Pharmacy Issues Voluntary Nationwide Recall of Prednisolone and Gatifloxacin Ophthalmic Solution 1%/0.5% Sterile Due to Small Particulate Floating in the Solution
Promise Pharmacy is voluntarily recalling one lot of Prednisolone and Gatifloxacin Ophthalmic Solution 1%/0.5% sterile, 3ml vials, to the patient consumer level. The product has been found to have unidentified small particulate floating in the solution. (Source: Food and Drug Administration)
Source: Food and Drug Administration - October 22, 2018 Category: Food Science Source Type: news

EyeGate ’ s Phase 3 EGP-437 study fails to show non-inferiority
Ophthalmalogical-focused developer EyeGate Pharma said this week that the Phase 3 study of its EGP-437 delivered through its EyeGate II drug delivery system did not show non-inferiority to the prednisolone acetate ophthalmic solution control group. The Phase 3 study was evaluating the safety and efficacy of the EGP-437 with the EyeGate II in patients with non-infectious anterior segment uveitis, the Waltham, Mass.-based company said. Read the whole story on our sister site, Drug Delivery Business News The post EyeGate’s Phase 3 EGP-437 study fails to show non-inferiority appeared first on MassDevice. (Source: Mass Device)
Source: Mass Device - September 6, 2018 Category: Medical Devices Authors: Fink Densford Tags: Clinical Trials Optical/Ophthalmic Pharmaceuticals Research & Development eyegatepharmaceuticals Source Type: news

Prednisolone Acetate 1% Ophthalmic Suspension (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - August 20, 2018 Category: Drugs & Pharmacology Source Type: news

Our daughter ’s eczema was out of control until we found Dr Aron
Life was like Groundhog Day for our family but then a South African dermatologist and his regimen improved things considerablyFucibet, Clobevate, hydrocortisone creams and gels, Daktacort, Epaderm, Elocon, E45, Dermol, Eumovate, calamine lotion, Pinetarsol solution, antihistamines, Piriton, Ucerax, wet wraps, dry wraps, cradle cap shampoo, all kinds of moisturisers, topical steroids, topical antibiotics, Prednisolone oral steroid, Elidel … GPs, dermatologists and consultants all offered their own variation on this list. Chekhov said, “When many solutions are offered, it means the problem is unsolvable,” ...
Source: Guardian Unlimited Science - August 5, 2018 Category: Science Authors: Chris Hall Tags: Eczema Parents and parenting Family Life and style Health & wellbeing Source Type: news

Pred-G (Gentamicin and Prednisolone Acetate) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 26, 2018 Category: Drugs & Pharmacology Source Type: news

Prednisolone Oral Solution (Prednisolone Sodium Phosphate Oral Solution) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - April 25, 2018 Category: Drugs & Pharmacology Source Type: news

Chemotherapy Induced Oral Mucositis: Prevention Is Possible Chemotherapy Induced Oral Mucositis: Prevention Is Possible
Does a mouthwash containing soluble prednisolone, nystatin, and salt reduce the rate of oral mucositis associated with chemotherapy?Chinese Clinical Oncology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 20, 2018 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

Abiraterone, Docetaxel Best With ADT for Metastatic Prostate Cancer
Abiraterone plus prednisolone/prednisone, or docetaxel, combined with ADT may be the most effective therapies for metastatic hormone-naive prostate cancer. (Source: CancerNetwork)
Source: CancerNetwork - March 19, 2018 Category: Cancer & Oncology Authors: Dave Levitan Tags: Genitourinary Cancers News Prostate Cancer Source Type: news

Itraconazole and prednisolone are compared for ABPA-complicating asthma treatment
Mon, 03/05/2018 - 15:03News blog (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - March 5, 2018 Category: Respiratory Medicine Authors: ROrritt Source Type: news

Pediapred (Prednisolone Sodium) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 15, 2018 Category: Drugs & Pharmacology Source Type: news

Flo-Pred (Prednisolone Acetate Oral Suspension) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 14, 2018 Category: Drugs & Pharmacology Source Type: news

Prednisolone Cuts Hospital Stay in Preschoolers With Wheeze Prednisolone Cuts Hospital Stay in Preschoolers With Wheeze
Reuters Health Information (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - January 30, 2018 Category: Allergy & Immunology Tags: Pulmonary Medicine News Source Type: news

A Role for Budesonide in Autoimmune Hepatitis? (CME/CE)
(MedPage Today) -- Effective second-line treatment after prednisolone failure (Source: MedPage Today Dermatology)
Source: MedPage Today Dermatology - January 30, 2018 Category: Dermatology Source Type: news

Prelone (Prednisolone (syrup)) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - January 19, 2018 Category: Drugs & Pharmacology Source Type: news

30.11.17: Not intended for U.S. and UK Media
Phase III trial of radium-223 dichloride in combination with abiraterone acetate and prednisone/prednisolone for patients with metastatic castration-resistant prostate cancer unblinded earlyDecision follows a recommendation from an Independent Data Monitoring Committeemehr ... (Source: Bayer IR Newsfeed: Events)
Source: Bayer IR Newsfeed: Events - November 29, 2017 Category: Pharmaceuticals Source Type: news

Prednisone vs. Prednisolone
Title: Prednisone vs. PrednisoloneCategory: MedicationsCreated: 11/1/2017 12:00:00 AMLast Editorial Review: 11/1/2017 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - November 1, 2017 Category: Drugs & Pharmacology Source Type: news

Oral steroid does not reduce lower respiratory tract infection symptoms in nonasthmatic adults
(The JAMA Network Journals) Among adults without asthma who developed an acute lower respiratory tract infection, use of the oral steroid prednisolone for five days did not reduce symptom duration or severity, according to a study published by JAMA. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - August 22, 2017 Category: International Medicine & Public Health Source Type: news

Orapred ODT (Prednisolone Sodium Phosphate) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - August 7, 2017 Category: Drugs & Pharmacology Source Type: news

Blephamide Ophthalmic Ointment (Sulfacetamide Sodium and Prednisolone Acetate ) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - July 31, 2017 Category: Drugs & Pharmacology Source Type: news

Alendronate Might Help Protect Against Hip Fracture in Patients Taking Prednisolone (FREE)
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM Use of alendronate is associated with lower hip fracture risk in older adults taking prednisolone, according to a retrospective cohort … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - July 12, 2017 Category: Primary Care Source Type: news

Alendronate Cuts Hip-Fracture Rates in High-Risk Elderly Alendronate Cuts Hip-Fracture Rates in High-Risk Elderly
Concomitant use of alendronate in the elderly on prednisolone dramatically reduces hip-fracture risk over a short-term follow-up.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 11, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

New study highlights patient concerns about glucocorticoid side effects
This study has shown that weight gain, insomnia and moon face were the top three most important side effects to patients taking glucocorticoids. Despite this, they are not widely studied, with many unanswered questions. "Research should be informed by patients, and targeted to provide patients with better information about these side effects of high importance." Arthritis Research UK's view Devi Rani Sagar, research liaison manager at Arthritis Research UK, said:"We believe that people with arthritis should get the recognition and support they deserve, and that's why we invest in research to find the...
Source: Arthritis Research UK - June 13, 2017 Category: Rheumatology Source Type: news

Addition of Abiraterone to ADT Tied to Improved Survival in Prostate Cancer (FREE)
By Kelly Young Edited by Susan Sadoughi, MD, and Andr é Sofair, MD, MPH The combination of androgen-deprivation therapy (ADT), abiraterone, and prednisolone is associated with improved survival among patients with locally-advanced or metastatic prostate cancer, according to the industry-funded STAMPEDE trial presented at the American Society of Cl inical Oncology's … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - June 5, 2017 Category: Primary Care Source Type: news

Pred Mild (Prednisolone Acetate Solution) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - May 19, 2017 Category: Drugs & Pharmacology Source Type: news

Prednisolone May Raise Cholesterol in Adrenal Insufficiency Prednisolone May Raise Cholesterol in Adrenal Insufficiency
The findings point to hydrocortisone as first-line treatment, but it is exceptionally expensive compared with prednisolone, at least in some countries, so studying lower doses of prednisolone may be worthwhile.Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - April 3, 2017 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news

Deltasone (Prednisone) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - January 24, 2017 Category: Drugs & Pharmacology Source Type: news

Blephamide Ophthalmic Ointment (Sulfacetamide Sodium and Prednisolone Acetate ) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 7, 2016 Category: Drugs & Pharmacology Source Type: news