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Prednisone vs. Prednisolone
Title: Prednisone vs. PrednisoloneCategory: MedicationsCreated: 11/1/2017 12:00:00 AMLast Editorial Review: 11/1/2017 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - November 1, 2017 Category: Drugs & Pharmacology Source Type: news

Oral steroid does not reduce lower respiratory tract infection symptoms in nonasthmatic adults
(The JAMA Network Journals) Among adults without asthma who developed an acute lower respiratory tract infection, use of the oral steroid prednisolone for five days did not reduce symptom duration or severity, according to a study published by JAMA. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - August 22, 2017 Category: International Medicine & Public Health Source Type: news

Orapred ODT (Prednisolone Sodium Phosphate) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - August 7, 2017 Category: Drugs & Pharmacology Source Type: news

Blephamide Ophthalmic Ointment (Sulfacetamide Sodium and Prednisolone Acetate ) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - July 31, 2017 Category: Drugs & Pharmacology Source Type: news

Alendronate Might Help Protect Against Hip Fracture in Patients Taking Prednisolone (FREE)
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM Use of alendronate is associated with lower hip fracture risk in older adults taking prednisolone, according to a retrospective cohort … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - July 12, 2017 Category: Primary Care Source Type: news

Alendronate Cuts Hip-Fracture Rates in High-Risk Elderly Alendronate Cuts Hip-Fracture Rates in High-Risk Elderly
Concomitant use of alendronate in the elderly on prednisolone dramatically reduces hip-fracture risk over a short-term follow-up.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 11, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

New study highlights patient concerns about glucocorticoid side effects
This study has shown that weight gain, insomnia and moon face were the top three most important side effects to patients taking glucocorticoids. Despite this, they are not widely studied, with many unanswered questions. "Research should be informed by patients, and targeted to provide patients with better information about these side effects of high importance." Arthritis Research UK's view Devi Rani Sagar, research liaison manager at Arthritis Research UK, said:"We believe that people with arthritis should get the recognition and support they deserve, and that's why we invest in research to find the...
Source: Arthritis Research UK - June 13, 2017 Category: Rheumatology Source Type: news

Addition of Abiraterone to ADT Tied to Improved Survival in Prostate Cancer (FREE)
By Kelly Young Edited by Susan Sadoughi, MD, and Andr é Sofair, MD, MPH The combination of androgen-deprivation therapy (ADT), abiraterone, and prednisolone is associated with improved survival among patients with locally-advanced or metastatic prostate cancer, according to the industry-funded STAMPEDE trial presented at the American Society of Cl inical Oncology's … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - June 5, 2017 Category: Primary Care Source Type: news

Pred Mild (Prednisolone Acetate Solution) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - May 19, 2017 Category: Drugs & Pharmacology Source Type: news

Prednisolone May Raise Cholesterol in Adrenal Insufficiency Prednisolone May Raise Cholesterol in Adrenal Insufficiency
The findings point to hydrocortisone as first-line treatment, but it is exceptionally expensive compared with prednisolone, at least in some countries, so studying lower doses of prednisolone may be worthwhile.Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - April 3, 2017 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news

Deltasone (Prednisone) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - January 24, 2017 Category: Drugs & Pharmacology Source Type: news

Blephamide Ophthalmic Ointment (Sulfacetamide Sodium and Prednisolone Acetate ) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 7, 2016 Category: Drugs & Pharmacology Source Type: news

Prednisolone (Prednisolone Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 29, 2016 Category: Drugs & Pharmacology Source Type: news

Prednisolone Tx Bumps Up Body Mass, Fat in RA (CME/CE)
(MedPage Today) -- But two different high-dose regimens didn't lead to fat redistribution (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - June 14, 2016 Category: Rheumatology Source Type: news

Lupus patients 'at higher risk of developing other health conditions'
People with lupus are at a greater risk of developing other health conditions than members of the general population.This is according to a new study conducted by the University of Nottingham and the Arthritis Research UK Primary Care Centre at Keele University, which examined the frequency of comorbidities associated with systemic lupus erythematosus in the UK between 1999 and 2012.A broad UK study Published in the medical journal Arthritis Care & Research, the study drew upon data from the UK Clinical Practice Research Datalink, identifying cases of lupus and matching each one by age, gender and practice to four heal...
Source: Arthritis Research UK - May 26, 2016 Category: Rheumatology Source Type: news

New study highlights diabetes link to glucocorticoid treatments for arthritis
A new UK study has provided insights into the potential risk of diabetes that exists for arthritis patients who are being treated with glucocorticoid therapy.This type of steroid therapy is a well-established therapeutic option that is prescribed to around half of patients with rheumatoid arthritis. However, it is a known risk factor for developing diabetes.The new research, led by the Arthritis Research UK Centre for Epidemiology at the University of Manchester, looked at the records of more than 20,000 patients with rheumatoid arthritis in the UK, and provided fresh evidence about how this association works.A greater ris...
Source: Arthritis Research UK - May 4, 2016 Category: Rheumatology Source Type: news

Prednisolone, Indomethacin Similarly Effective for Acute Gout
Oral prednisolone is as effective as indomethacin for relieving pain in acute gout and should be considered a first-line treatment option, according to a report published online in Annals of Internal Medicine. (Source: Caring for the Ages)
Source: Caring for the Ages - March 30, 2016 Category: Health Management Authors: Mary Ann Moon Source Type: news

Oral Steroids, NSAIDs Equally Safe, Effective for Acute GoutOral Steroids, NSAIDs Equally Safe, Effective for Acute Gout
A large, multicenter randomized trial found that oral prednisolone and oral indomethacin were equally effective at reducing acute gout pain in patients presenting to emergency departments. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 23, 2016 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Steroid May Be Safe, Effective Gout Treatment, Study Finds
MONDAY, Feb. 22, 2016 -- A steroid pill may be as good as a nonsteroidal anti-inflammatory drug (NSAID) for treating painful gout, new research suggests. Researchers who compared the steroid prednisolone with the arthritis medication indomethacin... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 23, 2016 Category: Journals (General) Source Type: news

Translating research into care
Updated Cochrane Review  from Cochrane Kidney and Transplat Group is making an impact in care.‘It’s not every day we get to see the immediate clinical translation of our research into care for our next patient,’ says Jonathan Craig, Coordinating Editor of the Cochrane Kidney and Transplant Group. ‘Which makes it quite striking and genuinely pleasing when we are able to do so. In the case of a recent review update, we’re seeing first hand how our findings can directly translate into greater certainty and better outcomes.’Published in March 2015, the updated Corticosteroid therapy for...
Source: Cochrane News and Events - January 28, 2016 Category: Information Technology Authors: mumoquit at cochrane.org Source Type: news

Dexamethasone vs Prednisone in Pediatric AsthmaDexamethasone vs Prednisone in Pediatric Asthma
Is there any difference in using dexamethasone vs prednisone/prednisolone to treat hospitalized children with asthma? Medscape Pediatrics (Source: Medscape Pediatrics Headlines)
Source: Medscape Pediatrics Headlines - October 19, 2015 Category: Pediatrics Tags: Pediatrics Viewpoint Source Type: news

Allergan Issues Voluntary Nationwide Recall In The U.S. Of Specific Lots Of REFRESH® Lacri-Lube®, REFRESH P.M. ®,
Allergan plc, today announced that it is conducting a voluntary recall down to consumer level of specific lots of its REFRESH® Lacri-Lube® 3.5g and 7g for dry eye, REFRESH P.M.® 3.5g for dry eye, FML® (fluorometholone ophthalmic ointment) 0.1% (sterile ophthalmic ointment topical anti-inflammatory agent for ophthalmic use, 3.5g), and Blephamide® (sulfacetamide sodium and prednisolone acetate ophthalmic ointment, USP) 10%/0.2% sterile topical ophthalmic ointment combining an antibacterial and a corticosteroid, 3.5g. (Source: Food and Drug Administration)
Source: Food and Drug Administration - August 24, 2015 Category: Food Science Source Type: news

Choose Prednisolone over Pentoxifylline for Alcoholic Hepatitis (FREE)
By Atif Zaman, MD, MPH Dr. Zaman is an associate editor of NEJM Journal Watch Gastroenterology, from which this story was adapted.Prednisolone might benefit certain groups with alcoholic hepatitis (AH), despite a nonsignificant finding for short-term mortality reduction overall, according to a … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - April 23, 2015 Category: Primary Care Source Type: news

No Mortality Benefit From Pentoxifylline in Alcoholic Hepatitis (CME/CE)
(MedPage Today) -- But prednisolone improved short-term survival. (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - April 22, 2015 Category: Psychiatry Source Type: news

Frequent antibiotic use linked to higher type 2 diabetes risk
Conclusion This large population-based study found a higher risk of diabetes in people taking between two and five courses of antibiotics over a year before diagnosis. This risk was even higher after more than five courses. Strengths of the study include its large sample size, direct relevance to the UK, and the accuracy of the data. Despite the strengths, the study does not prove that antibiotics cause diabetes, as its design cannot prove cause and effect. There are both plausible explanations for how antibiotic use may cause diabetes, and how the development of diabetes may cause more antibiotic use.  For example...
Source: NHS News Feed - March 25, 2015 Category: Consumer Health News Tags: Diabetes Medication Source Type: news

10 Things to Expect When You Have Cancer
This article originally appeared on reimagine.me a new online magazine for those who have been touched by cancer, and an education resource that teaches a powerful set of skills to start feeling better immediately. (Source: Healthy Living - The Huffington Post)
Source: Healthy Living - The Huffington Post - December 12, 2014 Category: Consumer Health News Source Type: news

Rituxan May Be New Tx Option in EGPA
(MedPage Today) -- High rates of improvement and reduced need for prednisolone in eosinophilic granulomatosis with polyangiitis. (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - December 8, 2014 Category: Pediatrics Source Type: news

STOPAH: Only Steroid Reduces Alcoholic Hepatitis Death RiskSTOPAH: Only Steroid Reduces Alcoholic Hepatitis Death Risk
In more than 1000 adults with severe alcoholic hepatitis, prednisolone was associated with a lower 28-day mortality rate; pentoxifylline offered no benefit. Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - November 16, 2014 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Grandmother dies after receiving wrong prescription
Dawn Britton had been prescribed Prednisolone but was given Gliclazide by staff at Jhoots Pharmacy in Bristol (Source: Telegraph Health)
Source: Telegraph Health - October 20, 2014 Category: Consumer Health News Tags: Dawn Britton Prednisolone wrong prescription died Jhoots Pharmacy Gliclazide inquest Source Type: news

IMPI: No Immunotherapy Benefit in Tuberculous PericarditisIMPI: No Immunotherapy Benefit in Tuberculous Pericarditis
Although prednisolone might be appropriate in some patients, the authors propose, neither the glucocorticoid nor M indicus pranii immunotherapy improved survival in the 1400-patient trial. Heartwire (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 8, 2014 Category: Consumer Health News Tags: Cardiology News Source Type: news

ESC: Mixed Results with Steroids in TB Pericarditis
BARCELONA (MedPage Today) -- Adding steroids to anti-tuberculosis treatment for patients with tuberculous pericarditis can reduce the risk of complication and the resulting hospital admission, but adding prednisolone to tuberculosis treatment did not reduce the risk of death, researchers said here. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - September 3, 2014 Category: Primary Care Source Type: news

prednisolone (Flo-Pred, Pediapred, Orapred, Orapred ODT)
Title: prednisolone (Flo-Pred, Pediapred, Orapred, Orapred ODT)Category: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 8/7/2014 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - August 7, 2014 Category: Rheumatology Source Type: news

Bayer starts patient enrolment in Phase III prostate cancer trial
Bayer HealthCare has started patient enrolment in a new Phase III trial of radium-223 dichloride (radium-223, Xofigo) in combination with abiraterone acetate and prednisone/prednisolone to treat asymptomatic or mildly symptomatic chemotherapy-naïve p… (Source: Drug Development Technology)
Source: Drug Development Technology - April 4, 2014 Category: Pharmaceuticals Source Type: news

Bifunctional Antibody Fragment-Based Fusion Proteins for the Targeted Elimination of Pathogenic T-Cell Subsets
Pathogenic effector T cells are key contributors to autoimmune diseases such as systemic lupus erythematosus (SLE). General inhibition of T cells using, e.g., methotrexate, prednisolone, or TNF blockers, has prominent therapeutic effects frequently at the cost of severe long-term side effects and toxicity. Therefore, targeted strategies that can selectively inhibit or eliminate pathogenic T cells are sought after as a new approach to safely block perpetual inflammatory T-cell responses and inhibit concomitant progressive tissue destruction. Of particular interest in this respect is the use of the so-called single-chain fra...
Source: Springer protocols feed by Immunology - February 7, 2014 Category: Allergy & Immunology Source Type: news

Prednisolone or Dexamethasone for Acute Asthma ExacerbationsPrednisolone or Dexamethasone for Acute Asthma Exacerbations
Which medication is most effective in the management of acute asthma exacerbations in children? Archives of Disease in Childhood (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 13, 2013 Category: Consumer Health News Tags: Pediatrics Journal Article Source Type: news

Severe Alcoholic Hepatitis: Combination Therapy No Better
(Ivanhoe Newswire) –Four weeks of treatment with a combination of the drug pentoxifylline and the corticosteroid prednisolone did not improve survival compared with just prednisolone in 270 patients with severe alcoholic hepatitis. (Source: Medical Headlines From Ivanhoe.com)
Source: Medical Headlines From Ivanhoe.com - September 12, 2013 Category: Consumer Health News Source Type: news

Combination therapy for severe alcoholic hepatitis does not result in improved survival
Four weeks of treatment with a combination of the drug pentoxifylline and the corticosteroid prednisolone did not improve 6-month survival compared with prednisolone alone in 270 patients with severe alcoholic hepatitis, according to a study in the September 11 issue of JAMA. Treatment of severe forms of alcoholic hepatitis is extremely challenging because of the poor outcome. European and U.S. guidelines recommend the use of prednisolone or pentoxifylline in patients with severe alcoholic hepatitis... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 11, 2013 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

LCNDG Rapid Review: Bortezomib for first-line, transplant unsuitable multiple myeloma
Source: London Cancer New Drugs Group Area: Evidence> Drug Specific Reviews There are no trials directly comparing bortezomib, melphalan, and prednisolone versus thalidomide-based regimens in patients with multiple myeloma who are not able to receive high-dose therapy and stem cell transplant.   The phase III open-label randomised control trial investigating melphalan-prednisolone (control arm) against bortezomib-melphalan-prednisolone (bortezomib arm) reported a median time to progression of 24 months in the bortezomib arm and 16.6 months in the control arm (hazard ratio 0.48; P
Source: NeLM - Drug Specific Reviews - February 12, 2013 Category: Drugs & Pharmacology Source Type: news

Abiraterone (Zytiga®) approved in the EU for treatment of metastatic castration-resistant prostate cancer prior to chemotherapy
Source: BioSpace Area: News According to BioSpace, the European Commission (EC) has approved an extension to the license of abiraterone to include its use, in combination with prednisone or prednisolone, for the treatment of metastatic castration-resistant prostate cancer (mCRPC), in adult men who are asymptomatic or mildly symptomatic after failure of androgen deprivation therapy in whom chemotherapy is not yet clinically indicated. Abiraterone has until now has been approved only for use in men with mCRPC whose disease has progressed on or after a docetaxel-based chemotherapy regimen.   The approval follows a ...
Source: NeLM - News - January 14, 2013 Category: Drugs & Pharmacology Source Type: news

RCT: Immunosuppression for progressive membranous nephropathy
Source: Lancet Area: News There is considerable uncertainty regarding the optimum therapeutic management of idiopathic membranous nephropathy which can lead to end-stage renal disease in more than 20% of patients. The benefits of immunosuppressive therapy have been demonstrated in some patients, but not in those patients with declining renal function.   To investigate therapeutic options in this subset, this randomised controlled trial, undertaken in 37 UK renal units, recruited adult patients with biopsy-proven idiopathic membranous nephropathy, a plasma creatinine concentration of less than 300 micromol/L, and ...
Source: NeLM - News - January 9, 2013 Category: Drugs & Pharmacology Source Type: news