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Specialty: Rheumatology
Condition: Arthritis

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Total 260 results found since Jan 2013.

Cardiovascular risk and mortality in rheumatoid arthritis compared with diabetes mellitus and the general population
ConclusionThis study demonstrates that RA is associated with an increased risk of HF, MI, stroke and coronary revascularization than found in the GP but without reaching the risk levels observed in DM patients.
Source: Rheumatology - September 27, 2020 Category: Rheumatology Source Type: research

Cardiovascular morbidity and mortality in patients with spondyloarthritis: A meta ‐analysis
ConclusionsOur meta ‐analysis demonstrated that patients with SpA have a significantly increased risks of MI and stroke, but without a significant increase in the all‐cause mortality, than that in the general population. The higher risk of CV in patients with SpA than that in the general population indicates the ne ed for strict risk factor correction and disease management.
Source: International Journal of Rheumatic Diseases - September 24, 2020 Category: Rheumatology Authors: Ji Hyoun Kim, In Ah Choi Tags: ORIGINAL ARTICLE Source Type: research

Cardiovascular and renal morbidity in Takayasu arteritis: a population ‐based retrospective cohort study from UK
ConclusionCardiovascular morbidity was increased in patients with TA attending primary care services in the UK. Treatment with statins and anti ‐platelets in these patients was suboptimal.
Source: Arthritis and Rheumatology - September 22, 2020 Category: Rheumatology Authors: Ruchika Goel, Joht Singh Chandan, Rasiah Thayakaran, Nicola J Adderley, Krishnarajah Nirantharakumar, Lorraine Harper Tags: FULL LENGTH Source Type: research

Cardiovascular events and change in cholesterol levels in patients with rheumatoid arthritis treated with tocilizumab: data from the REGATE Registry.
CONCLUSIONS: In current practice, cardiovascular events occurring under TCZ treatment is in the range of what is expected in RA patients despite a global increase in cholesterol levels. PMID: 32896267 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - September 12, 2020 Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research

Anti –Citrullinated Protein Antibody Specificities, Rheumatoid Factor Isotypes, and Incident Cardiovascular Events in Patients With Rheumatoid Arthritis
ConclusionRF isotypes and ACPAs are associated with future CV events in patients with RA. ACPA levels and number of subspecificities seem more important than the occurrence of particular subspecificities, and these associations were not explained by a history of ever smoking.
Source: Arthritis and Rheumatology - September 6, 2020 Category: Rheumatology Authors: Helga Westerlind, Johan R önnelid, Monika Hansson, Lars Alfredsson, Linda Mathsson‐Alm, Guy Serre, Martin Cornillet, Rikard Holmdahl, Per‐Johan Jakobsson, Karl Skriner, Lars Klareskog, Saedis Saevarsdottir, Johan Askling Tags: Original Article Source Type: research

Deficiency of adenosine deaminase 2 (DADA2) in Adults and Children: Experience from India
ConclusionsWe present the first case series of DADA2 patients from India. We highlight the presentation of DADA2 in adults and raise awareness of this syndrome for both adult and paediatric care providers.
Source: Arthritis and Rheumatology - September 5, 2020 Category: Rheumatology Authors: Aman Sharma, Gsrsnk Naidu, Vikas Sharma, Saket Jha, Aaadhar Dhooria, Varun Dhir, Prateek Bhatia, Vishal Sharma, Sagar Bhattad, Chengappa, Vikas Gupta, Durga Prasanna Misra, Pallavi Pimpale Chavan, Sourabh Malaviya, Rajkiran Dudam, Banwari Tags: FULL LENGTH Source Type: research

The risk of cardiovascular events associated with disease-modifying antirheumatic drugs in rheumatoid arthritis.
CONCLUSION: Abatacept and TNFi were associated with decreased risk of CVD compared to csDMARDs. Minimizing glucocorticoid use and optimizing MTX dose may improve CV outcomes in patients with RA. PMID: 32801134 [PubMed - as supplied by publisher]
Source: Journal of Rheumatology - August 18, 2020 Category: Rheumatology Tags: J Rheumatol Source Type: research

Biologics May Prevent Cardiovascular Events in Rheumatoid Arthritis by Inhibiting Coronary Plaque Formation and Stabilizing High ‐Risk Lesions
ConclusionOur findings indicate that in RA, biologic DMARD use is associated with reduced CVD risk, protective calcification of noncalcified lesions, and lower likelihood of new plaque formation in patients with early atherosclerosis.
Source: Arthritis and Rheumatology - August 6, 2020 Category: Rheumatology Authors: George A. Karpouzas, Sarah R. Ormseth, Elizabeth Hernandez, Matthew J. Budoff Tags: Original Article Source Type: research

Is There a Brain/Heart Interaction in Rheumatoid Arthritis and Seronegative Spondyloartropathies? A Combined Brain/Heart Magnetic Resonance Imaging Reveals the Answer
AbstractPurpose of ReviewTo present the interaction between brain/heart and emphasize the role of combined brain/heart magnetic resonance imaging (MRI) in patients with rheumatoid arthritis (RA) and other seronegative spondyloarthropathies (SNA).Recent FindingsBoth traditional cardiovascular disease (CVD) risk factors and intrinsic RA/SNA features contribute to the increased CVD-related morbidity/mortality. CVD in RA usually occurs a decade earlier than age- and sex-matched controls, and RA patients are twice more likely to develop myocardial infarction irrespective of age, history of prior CVD, and traditional CVD risk fa...
Source: Current Rheumatology Reports - June 18, 2020 Category: Rheumatology Source Type: research

Antiphospholipid Syndrome is still a rare disease: the estimated prevalence in Piedmont and Aosta Valley
AbstractWe read with interest the recent article by Duarte ‐García, A. et al. where they reported an estimated prevalence of the antiphospholipid syndrome (APS) of 50 cases per 100,000 population. APS is an autoimmune disorder characterized by thrombotic events, pregnancy morbidity, or both in the presence of persistent positivity for antiphospholipid an tibodies (aPL). While APS is often held as the most common acquired thrombophilia, the global incidence and the prevalence of APS in the general population still need to be fully elucidated. Some reports estimate an incidence of 5 cases per 100,000 persons per year and ...
Source: Arthritis and Rheumatology - June 16, 2020 Category: Rheumatology Authors: Massimo Radin, Savino Sciascia, Mario Bazzan, Tiziana Bertero, Renato Carignola, Barbara Montaruli, Antonella Vaccarino, Erika Montabone, Irene Cecchi, Elena Rubini, Dario Roccatello, Simone Baldovino, on behalf of the Piedmont, Aosta Valley APS Consortiu Tags: LETTER TO THE EDITOR Source Type: research

Anti ‐citrullinated protein antibody specificities, rheumatoid factor isotypes and incident cardiovascular events in patients with rheumatoid arthritis
ConclusionsRF isotypes and ACPA are associated with future CV events. ACPA levels and number of sub ‐specificities seem more important than the occurrence of particular sub‐specificities. These associations were not explained by smoking.
Source: Arthritis and Rheumatology - May 30, 2020 Category: Rheumatology Authors: Helga Westerlind, Johan R önnelid, Monika Hansson, Lars Alfredsson, Linda Mathsson‐Alm, Guy Serre, Martin Cornillet, Rikard Holmdahl, Per‐Johan Jakobsson, Karl Skriner, Lars Klareskog, Saedis Saevarsdottir, Johan Askling Tags: FULL LENGTH Source Type: research

Biologics may prevent cardiovascular events in rheumatoid arthritis by inhibiting coronary plaque formation and stabilizing high ‐risk lesions
ConclusionIn rheumatoid arthritis, bDMARD use associated with reduced CVD risk, protective calcification of non ‐calcified lesions and lower likelihood of new plaque formation in patients with early atherosclerosis.
Source: Arthritis and Rheumatology - April 20, 2020 Category: Rheumatology Authors: George A Karpouzas, Sarah R Ormseth, Elizabeth Hernandez, Matthew J Budoff Tags: FULL LENGTH Source Type: research

Gout is associated with an increased risk for incident heart failure among older adults: the REasons for Geographic And Racial Differences in Stroke (REGARDS) cohort study
Gout has been associated with a higher risk for coronary heart disease (CHD) and stroke in some prior studies. Few studies have assessed the association of gout with incident heart failure (HF).
Source: Arthritis Research and Therapy - April 16, 2020 Category: Rheumatology Authors: Lisandro D. Colantonio, Kenneth G. Saag, Jasvinder A. Singh, Ligong Chen, Richard J. Reynolds, Angelo Gaffo, Timothy B. Plante, Jeffrey R. Curtis, S. Louis Bridges Jr., Emily B. Levitan, Ninad S. Chaudhary, George Howard, Monika M. Safford, Paul Muntner a Tags: Research article Source Type: research