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Specialty: Rheumatology
Condition: Arthritis

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Total 260 results found since Jan 2013.

Association Between Ischemic Stroke and Tumor Necrosis Factor Inhibitor Therapy in Patients With Rheumatoid Arthritis
ConclusionExposure to TNFi does not appear to influence the occurrence of ischemic stroke in the medium term in patients with RA. The impact on mortality after ischemic stroke remains inconclusive.
Source: Arthritis and Rheumatism - May 25, 2016 Category: Rheumatology Authors: Audrey S. L. Low, Mark Lunt, Louise K. Mercer, Kath D. Watson, William G. Dixon, Deborah P. M. Symmons, Kimme L. Hyrich Tags: Rheumatoid Arthritis Source Type: research

Herpes Zoster and the Risk for Stroke in Patients with Autoimmune Diseases
Conclusion: In patients with autoimmune diseases, incident HZ was associated with up to a two‐fold increased risk for stroke in the subsequent few months. These data provide urgency for developing strategies to reduce the risk of VZV. This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatism - September 1, 2016 Category: Rheumatology Authors: L.H. Calabrese, F. Xie, H. Yun, K. Winthrop, J.W. Baddley, C. Calabrese, J.R. Curtis Tags: Full Length Source Type: research

Herpes Zoster and the Risk of Stroke in Patients With Autoimmune Diseases
ConclusionIn patients with autoimmune diseases, incident HZ was associated with as much as a 2‐fold increased risk of stroke in the subsequent few months. These data underscore the urgency of developing strategies for reducing the risk of varicella‐zoster virus.
Source: Arthritis and Rheumatism - January 27, 2017 Category: Rheumatology Authors: Leonard H. Calabrese, Fenglong Xie, Huifeng Yun, Kevin L. Winthrop, John W. Baddley, Cassandra Calabrese, Jeffrey R. Curtis Tags: Autoimmune Disease Source Type: research

Gout as a risk factor for myocardial infarction and stroke in England: evidence from record linkage studies
Conclusion. Gout was associated with increased risk of stroke as well as MI. These findings should be considered by clinicians and may have implications for preventive management of circulatory disease risks in people with gout.
Source: Rheumatology - November 14, 2013 Category: Rheumatology Authors: Seminog, O. O., Goldacre, M. J. Tags: Crystal Arthritis CLINICAL SCIENCE Source Type: research

Artificial intelligence-based preventive, personalized and precision medicine for cardiovascular disease/stroke risk assessment in rheumatoid arthritis patients: a narrative review
AbstractThe challenges associated with diagnosing and treating cardiovascular disease (CVD)/Stroke in Rheumatoid arthritis (RA) arise from the delayed onset of symptoms. Existing clinical risk scores are inadequate in predicting cardiac events, and conventional risk factors alone do not accurately classify many individuals at risk. Several CVD biomarkers consider the multiple pathways involved in the development of atherosclerosis, which is the primary cause of CVD/Stroke in RA. To enhance the accuracy of CVD/Stroke risk assessment in the RA framework, a proposed approach involves combining genomic-based biomarkers (GBBM) ...
Source: Rheumatology International - September 11, 2023 Category: Rheumatology Source Type: research

Occurrence and relative risk of stroke in incident and prevalent contemporary rheumatoid arthritis
Conclusion The magnitude of stroke risk is lower than for ischaemic heart disease in RA, and the evolvement of this risk from RA diagnosis may be slower. This suggests different driving forces behind these two RA co-morbidities and has implications for the clinical follow-up of patients with RA.
Source: Annals of the Rheumatic Diseases - February 25, 2013 Category: Rheumatology Authors: Holmqvist, M., Gransmark, E., Mantel, A., Alfredsson, L., Jacobsson, L. T. H., Wallberg-Jonsson, S., Askling, J. Tags: Immunology (including allergy), Connective tissue disease, Degenerative joint disease, Musculoskeletal syndromes, Rheumatoid arthritis Clinical and epidemiological research Source Type: research

Risk of Myocardial Infarction and Stroke in Patients with Granulomatosis with Polyangiitis: A Population‐Based Study
Conclusion: GPA patients have a significantly increased risk of MI, with a non‐statistically significant trend towards increased risk of ischemic stroke. Monitoring for this complication and vigilance in modifying risk factors is particularly warranted in this patient population, especially early after diagnosis. This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatism - May 22, 2016 Category: Rheumatology Authors: J. Antonio Aviña‐Zubieta, Alice Mai, Neda Amiri, Natasha Dehghan, Ju Ann Tan, Eric C. Sayre, Hyon K. Choi Tags: Full Length Source Type: research

Risk of Myocardial Infarction and Stroke in Patients With Granulomatosis With Polyangiitis (Wegener's): A Population ‐Based Study
ConclusionPatients with GPA have a significantly increased risk of MI and a non–statistically significant trend toward an increased risk of ischemic stroke. Monitoring for this complication and vigilance in modifying risk factors are particularly warranted in this patient population, especially early after the diagnosis of GPA.
Source: Arthritis and Rheumatism - September 28, 2016 Category: Rheumatology Authors: J. Antonio Avi ña‐Zubieta, Alice Mai, Neda Amiri, Natasha Dehghan, Ju Ann Tan, Eric C. Sayre, Hyon K. Choi Tags: Full Length Source Type: research

Risk of Myocardial Infarction and Stroke in Newly Diagnosed Systemic Lupus Erythematosus: A General Population ‐Based Study
Conclusion: Patients with SLE have an increased risk of cardiovascular events, particularly during the first year after diagnosis. Increased vigilance in monitoring for these potentially fatal outcomes and their modifiable risk factors is recommended in this patient population. This article is protected by copyright. All rights reserved.
Source: Arthritis Care and Research - January 26, 2017 Category: Rheumatology Authors: J. Antonio Avi ña‐Zubieta, Fergus To, Kateryna Vostretsova, Mary De Vera, Eric C. Sayre, John M. Esdaile Tags: Original Article Source Type: research

Exploring metabolic and inflammatory abnormalities in rheumatoid arthritis patients developing stroke disease: a case-control study using electronic medical record data in northern China
ConclusionsA close monitoring is required for RA patients with dyslipidemia and elevated inflammatory markers, and the primary stroke preventive strategies should be directed against these risk factors.
Source: Clinical Rheumatology - February 7, 2019 Category: Rheumatology Source Type: research

High risk of pulmonary embolism and deep venous thrombosis but not of stroke in granulomatosis with polyangiitis (Wegener’s)
Conclusion: The present study confirms that GPA patients have a markedly increased risk of venous thromboembolism. We did not observe an increased risk of stroke in our cohort. Thus, our observations demonstrate a differential impact of GPA and/or its treatment on the risk of various vascular events. © 2014 American College of Rheumatology.
Source: Arthritis Care and Research - July 29, 2014 Category: Rheumatology Authors: Mikkel Faurschou, Niels Obel, Bo Baslund Tags: Original Article Source Type: research

Methotrexate might reduce ischemic stroke in patients with rheumatoid arthritis: a population ‐based retrospective cohort study
ConclusionsAt a dosage of > 0.5 defined daily dose, short‐term methotrexate might decrease ischemic stroke risk in RA patients, while hydroxychloroquine and sulfasalazine were neutral.
Source: APLAR Journal of Rheumatology - January 1, 2018 Category: Rheumatology Authors: Hong ‐Wei Tam, Chyong‐Mei Chen, Pui‐Ying Leong, Chao‐Hsi Chen, Yuan‐Chao Li, Yu‐Hsun Wang, Li‐Chi Lin, Jeng‐Yuan Chiou, James Cheng‐Chung Wei Tags: Original Article Source Type: research

Genetic Variants of the NLRP3 Inflammasome Are Associated with Stroke in Patients with Rheumatoid Arthritis.
CONCLUSION: Genetic variants of the NLRP3 inflammasome influence the risk of stroke/TIA, but not of MI/angina pectoris in Swedish patients with established RA. PMID: 26178285 [PubMed - as supplied by publisher]
Source: J Rheumatol - July 15, 2015 Category: Rheumatology Authors: Kastbom A, Ärlestig L, Rantapää-Dahlqvist S Tags: J Rheumatol Source Type: research

Trends in Hospitalizations Due to Acute Coronary Syndromes and Stroke in Patients with Systemic Lupus Erythematosus, 1996 To 2012
Conclusion: Increased awareness of the burden of CVD in patients with SLE has not yet translated into decreases in hospitalizations for acute myocardial infarction or stroke. This may be due to barriers in implementation of CVD risk factor modification, or SLE‐specific risks that have not yet been identified or effectively targeted. This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatism - June 5, 2016 Category: Rheumatology Authors: Maria G. Tektonidou, Zhong Wang, Michael M. Ward Tags: Brief Report Source Type: research