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Specialty: Rheumatology
Condition: Arthritis

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Total 260 results found since Jan 2013.

Non-steroidal anti-inflammatory drugs and risk of cardiovascular disease in patients with rheumatoid arthritis: a nationwide cohort study
Conclusions The cardiovascular risk associated with NSAID use in RA patients was modest and significantly lower than in non-RA individuals. Moreover, only a few of the individual NSAIDs were associated with increased cardiovascular risk. NSAID use should be assessed in the individual patient based on the indication for pain relief and risk factors for adverse effects, and not automatically be avoided due to concerns of severe cardiovascular outcomes alone.
Source: Annals of the Rheumatic Diseases - July 3, 2014 Category: Rheumatology Authors: Lindhardsen, J., Gislason, G. H., Jacobsen, S., Ahlehoff, O., Olsen, A.-M. S., Ole Rintek Madsen, , Torp-Pedersen, C., Hansen, P. R. Tags: Immunology (including allergy), Biological agents, Connective tissue disease, Degenerative joint disease, Drugs: musculoskeletal and joint diseases, Musculoskeletal syndromes, Rheumatoid arthritis, Epidemiology Clinical and epidemiological research Source Type: research

Cardiovascular events in ankylosing spondylitis. An updated meta-analysis
This study aims to assess the risk of myocardial infarction (MI) and stroke in AS patients.
Source: Seminars in Arthritis and Rheumatism - October 17, 2014 Category: Rheumatology Authors: Sylvain Mathieu, Bruno Pereira, Martin Soubrier Source Type: research

The role of central sensitization in shoulder pain: A systematic literature review
Hyperexcitability of the central nervous system has been suggested to play an important role in pain experienced by patients with unilateral shoulder pain. A systematic literature review following the PRISMA guidelines was performed to evaluate the existing evidence related to the presence of central sensitization in patients with unilateral shoulder pain of different etiologies including those with chronic subacromial impingement syndrome. Studies addressing neuropathic pain (e.g. post-stroke shoulder pain) were not considered.
Source: Seminars in Arthritis and Rheumatism - November 13, 2014 Category: Rheumatology Authors: M.N. Sanchis, E. Lluch, J. Nijs, F. Struyf, M. Kangasperko Source Type: research

Cardiovascular events in ankylosing spondylitis: An updated meta-analysis
This study aims to assess the risk of myocardial infarction (MI) and stroke in AS patients.
Source: Seminars in Arthritis and Rheumatism - October 17, 2014 Category: Rheumatology Authors: Sylvain Mathieu, Bruno Pereira, Martin Soubrier Source Type: research

Psoriasis, psoriatic arthritis and cardiovascular risk: are we closer to a clinical recommendation?
The issue of vascular risk in chronic arthropathies and especially the magnitude of such risk and its clinical implications in daily practice are of considerable current importance. Similarly, the relative risk across distinct arthropathies and other chronic inflammatory conditions is debated. Ogdie et al1 report associations between psoriasis, psoriatic arthritis (PsA), rheumatoid arthritis (RA) and an increased risk of major adverse cardiovascular events (MACE—myocardial infarction, stroke and cardiovascular death) in data derived from the UK primary care registry. Results are stratified by use of disease-modifying...
Source: Annals of the Rheumatic Diseases - January 7, 2015 Category: Rheumatology Authors: Kristensen, S. L., McInnes, I. B., Sattar, N. Tags: Immunology (including allergy), Inflammation, Biological agents, Connective tissue disease, Degenerative joint disease, Drugs: musculoskeletal and joint diseases, Musculoskeletal syndromes, Rheumatoid arthritis, Epidemiology Editorials Source Type: research

Racial and ethnic differences in mortality and cardiovascular events among patients with end‐stage renal disease due to lupus nephritis
Conclusion: Among patients with LN ESRD, Asians and Hispanics experienced lower mortality and CV event risks, while African Americans had higher mortality and CV event risks compared to Whites. This article is protected by copyright. All rights reserved.
Source: Arthritis Care and Research - January 1, 2015 Category: Rheumatology Authors: Jose A. Gómez‐Puerta, Candace H. Feldman, Graciela S. Alarcón, Hongshu Guan, Wolfgang C. Winkelmayer, Karen H. Costenbader Tags: Original Article Source Type: research

Hip osteoarthritis and the risk of all‐cause and disease‐specific mortality in older women: Population‐based cohort study
Conclusion RHOA was associated with an increased risk of all‐cause and CVD mortality among older white women followed for 16 years. Dissemination of evidence‐based physical activity and self‐management interventions for hip OA in community and clinical settings can improve physical function and might also contribute to lower mortality. This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatism - March 16, 2015 Category: Rheumatology Authors: Kamil E. Barbour, Li‐Yung Lui, Michael C. Nevitt, Louise B. Murphy, Charles G. Helmick, Kristina A. Theis, Marc C. Hochberg, Nancy E. Lane, Jennifer M. Hootman, Jane A. Cauley, Tags: Full Length Source Type: research

Disease activity in rheumatoid arthritis and the risk of cardiovascular events
Conclusions: Reduced time‐averaged disease activity in RA is associated with fewer CV events. This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatism - March 16, 2015 Category: Rheumatology Authors: D.H. Solomon, G Reed, J.M. Kremer, J.R. Curtis, M.E. Farkouh, L.R. Harrold, M.C. Hochberg, P Tsao, J Greenberg Tags: Full Length Source Type: research

Prevalence and risk factors of arthritis in a middle-aged and older Chinese population: the China Health and Retirement Longitudinal Study
Conclusion. Middle-aged and older Chinese adults had a high prevalence of arthritis. Cardiovascular disease is a novel risk factor for arthritis in this population.
Source: Rheumatology - March 24, 2015 Category: Rheumatology Authors: Li, C., Liu, T., Sun, W., Wu, L., Zou, Z.-Y. Tags: Rheumatoid Arthritis CLINICAL SCIENCE Source Type: research

Rheumatoid arthritis, anti‐CCP positivity, and cardiovascular disease risk in the Women's Health Initiative
Conclusion: Among postmenopausal women, RA was associated with 1.5‐2.5 higher CVD risk, strongly associated with CV risk factors, joint pain severity, and inflammation, but similar for anti‐CCP+ and RF+. This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatism - May 18, 2015 Category: Rheumatology Authors: Rachel H. Mackey, Lewis H. Kuller, Kevin D. Deane, Brian T. Walitt, Yuefang F. Chang, V. Michael Holers, William H. Robinson, Russell P. Tracy, Mark A. Hlatky, Charles Eaton, Simin Liu, Matthew S. Freiberg, Mehret Birru Talabi, Erik B. Schelbert, Larry W. Tags: Full Length Source Type: research

Association between pregnancy outcomes and cardiovascular deaths in women with systemic lupus erythematousus utilising Swedish population registries
Conclusion: MPS in pregnancy is associated with a higher risk of future primary cardiovascular death in women with SLE. This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatism - May 27, 2015 Category: Rheumatology Authors: May Ching Soh, Catherine Nelson‐Piercy, Fadia Dib, Magnus Westgren, Lesley McCowan, Dharmintra Pasupathy Tags: Brief Report Source Type: research

Epigenetic Aspects of Systemic Lupus Erythematosus
Abstract Autoimmune diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis, multiple sclerosis, autoimmune hepatitis, and inflammatory bowel disease have complex pathogeneses and the courses of events leading to these diseases are not well understood. The immune surveillance is a delicate balance between self and foreign as well as between tolerance and immune response. Exposure to certain environmental factors may impair this equilibrium, leading to autoimmune diseases, cancer, and the so-called “lifestyle diseases” such as atherosclerosis, heart attack, stroke, and obesity, among others. T...
Source: Rheumatology and Therapy - June 15, 2015 Category: Rheumatology Source Type: research

Hip Osteoarthritis and the Risk of All‐Cause and Disease‐Specific Mortality in Older Women: A Population‐Based Cohort Study
ConclusionRHOA was associated with an increased risk of all‐cause and CVD mortality among older white women followed up for 16 years. Dissemination of evidence‐based physical activity and self‐management interventions for hip OA in community and clinical settings can improve physical function and might also contribute to lower mortality.
Source: Arthritis and Rheumatism - June 26, 2015 Category: Rheumatology Authors: Kamil E. Barbour, Li‐Yung Lui, Michael C. Nevitt, Louise B. Murphy, Charles G. Helmick, Kristina A. Theis, Marc C. Hochberg, Nancy E. Lane, Jennifer M. Hootman, Jane A. Cauley, Tags: Osteoarthritis Source Type: research

Rheumatoid arthritis: Link between RA and cardiovascular disease risk
Nature Reviews Rheumatology 11, 382 (2015). doi:10.1038/nrrheum.2015.77 Data from >160,000 postmenopausal women included in the Women's Health Initiative indicate that women with RA are at 1.5–2.5-fold higher risk of cardiovascular disease (CVD) morbidity and mortality over 10 years compared with women without RA (outcomes assessed included coronary heart disease, stroke, CVD, fatal
Source: Nature Reviews Rheumatology - June 2, 2015 Category: Rheumatology Tags: Research Highlight Source Type: research

Rheumatoid Arthritis, Anti–Cyclic Citrullinated Peptide Positivity, and Cardiovascular Disease Risk in the Women's Health Initiative
ConclusionAmong postmenopausal women, RA was associated with 1.5–2.5‐fold higher CVD risk. CVD risk was strongly associated with CVD risk factors, joint pain severity, and inflammation, but not with anti‐CCP positivity or RF positivity.
Source: Arthritis and Rheumatism - August 26, 2015 Category: Rheumatology Authors: Rachel H. Mackey, Lewis H. Kuller, Kevin D. Deane, Brian T. Walitt, Yue‐Fang Chang, V. Michael Holers, William H. Robinson, Russell P. Tracy, Mark A. Hlatky, Charles B. Eaton, Simin Liu, Matthew S. Freiberg, Mehret Birru Talabi, Erik B. Schelbert, Larry Tags: Rheumatoid Arthritis Source Type: research