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Specialty: Rheumatology
Condition: Arthritis

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Total 260 results found since Jan 2013.

The role of central sensitization in shoulder pain: A systematic literature review
Hyperexcitability of the central nervous system has been suggested to play an important role in pain experienced by patients with unilateral shoulder pain. A systematic literature review following the PRISMA guidelines was performed to evaluate the existing evidence related to the presence of central sensitization in patients with unilateral shoulder pain of different etiologies including those with chronic subacromial impingement syndrome. Studies addressing neuropathic pain (e.g. post-stroke shoulder pain) were not considered.
Source: Seminars in Arthritis and Rheumatism - November 13, 2014 Category: Rheumatology Authors: M.N. Sanchis, E. Lluch, J. Nijs, F. Struyf, M. Kangasperko Source Type: research

Amelioration of experimental arthritis by stroke-induced immunosuppression is independent of Treg cell function
Conclusions MCAO ameliorates arthritis. The correlate of protection from arthritis is not the reduction of a particular pathogenic leucocyte subset or the preferential expansion or emergence of a protective cell population but the global reduction of leucocytes during arthritis.
Source: Annals of the Rheumatic Diseases - October 30, 2014 Category: Rheumatology Authors: Irmler, I. M., Gajda, M., Kamradt, T. Tags: Open access, Immunology (including allergy), Degenerative joint disease, Musculoskeletal syndromes Basic and translational research Source Type: research

Cardiovascular events in ankylosing spondylitis. An updated meta-analysis
This study aims to assess the risk of myocardial infarction (MI) and stroke in AS patients.
Source: Seminars in Arthritis and Rheumatism - October 17, 2014 Category: Rheumatology Authors: Sylvain Mathieu, Bruno Pereira, Martin Soubrier Source Type: research

Cardiovascular events in ankylosing spondylitis: An updated meta-analysis
This study aims to assess the risk of myocardial infarction (MI) and stroke in AS patients.
Source: Seminars in Arthritis and Rheumatism - October 17, 2014 Category: Rheumatology Authors: Sylvain Mathieu, Bruno Pereira, Martin Soubrier Source Type: research

High risk of pulmonary embolism and deep venous thrombosis but not of stroke in granulomatosis with polyangiitis (Wegener’s)
Conclusion: The present study confirms that GPA patients have a markedly increased risk of venous thromboembolism. We did not observe an increased risk of stroke in our cohort. Thus, our observations demonstrate a differential impact of GPA and/or its treatment on the risk of various vascular events. © 2014 American College of Rheumatology.
Source: Arthritis Care and Research - July 29, 2014 Category: Rheumatology Authors: Mikkel Faurschou, Niels Obel, Bo Baslund Tags: Original Article Source Type: research

Non-steroidal anti-inflammatory drugs and risk of cardiovascular disease in patients with rheumatoid arthritis: a nationwide cohort study
Conclusions The cardiovascular risk associated with NSAID use in RA patients was modest and significantly lower than in non-RA individuals. Moreover, only a few of the individual NSAIDs were associated with increased cardiovascular risk. NSAID use should be assessed in the individual patient based on the indication for pain relief and risk factors for adverse effects, and not automatically be avoided due to concerns of severe cardiovascular outcomes alone.
Source: Annals of the Rheumatic Diseases - July 3, 2014 Category: Rheumatology Authors: Lindhardsen, J., Gislason, G. H., Jacobsen, S., Ahlehoff, O., Olsen, A.-M. S., Ole Rintek Madsen, , Torp-Pedersen, C., Hansen, P. R. Tags: Immunology (including allergy), Biological agents, Connective tissue disease, Degenerative joint disease, Drugs: musculoskeletal and joint diseases, Musculoskeletal syndromes, Rheumatoid arthritis, Epidemiology Clinical and epidemiological research Source Type: research

The association between inflammatory markers, serum lipids and the risk of cardiovascular events in patients with rheumatoid arthritis
Conclusions This study provides evidence supporting the hypothesis that RA-related systemic inflammation plays a role in determining cardiovascular risk and a complex relationship between LDL and cardiovascular risk.
Source: Annals of the Rheumatic Diseases - June 6, 2014 Category: Rheumatology Authors: Zhang, J., Chen, L., Delzell, E., Muntner, P., Hillegass, W. B., Safford, M. M., Millan, I. Y. N., Crowson, C. S., Curtis, J. R. Tags: Editor's choice, Immunology (including allergy), Inflammation, Connective tissue disease, Degenerative joint disease, Musculoskeletal syndromes, Rheumatoid arthritis, Clinical diagnostic tests, Epidemiology Clinical and epidemiological research Source Type: research

A16: Long‐term follow‐up of 36 Pediatric Antiphospholipid Syndrome Patients: A Retrospective Study
Conclusion:Despite of prophylaxis with anticoagulants, new thrombotic events occurred in 25% of the patients and reaching the ideal prothrombin time to prevent thrombotic episodes was the major challenge, as nearly half of the patients had hemorrhagic events. Studies are necessary to identify ideal parameters for treating and monitoring children with antiphospholipid syndrome.
Source: Arthritis and Rheumatism - March 27, 2014 Category: Rheumatology Authors: Francisco Hugo Gomes, Luciana Carvalho, Paola Pinheiro, Tamara Resende, Virgínia Ferriani Tags: Poster Presentations Source Type: research

Tumor Necrosis Factor α Inhibitor Use and Decreased Risk for Incident Coronary Events in Rheumatoid Arthritis
ConclusionUse of TNFα inhibitors is associated with a decreased risk for CAD in RA; the risk decreases further with long‐term use. This should be considered when weighing the risks versus benefits of these medications.
Source: Arthritis Care and Research - February 24, 2014 Category: Rheumatology Authors: Androniki Bili, Xiaoqin Tang, Shruthi Pranesh, Rasa Bozaite, Stephanie J. Morris, Jana L. Antohe, H. Lester Kirchner, Mary Chester M. Wasko Tags: Rheumatoid Arthritis Source Type: research

Changes in Mortality Patterns Following Total Hip or Knee Arthroplasty Over the Past Two Decades: A Nationwide Cohort Study
ConclusionMortality rates following elective THA and TKA have decreased substantially since the early 1990s, despite patients having more presurgical comorbidity. These findings are reassuring for patients undergoing elective THA or TKA.
Source: Arthritis and Rheumatism - January 27, 2014 Category: Rheumatology Authors: Arief Lalmohamed, Peter Vestergaard, Anthonius Boer, Hubertus G. M. Leufkens, Tjeerd P. Staa, Frank Vries Tags: Arthritis Surgery Source Type: research

Changes in mortality patterns following total hip or knee replacement over the past two decades: A nationwide cohort study
Conclusion: Mortality rates following elective THR and TKR have decreased substantially since the early 90s, despite operated patients having more comorbidity. These findings are reassuring for patients undergoing elective THR or TKR. © 2013 American College of Rheumatology.
Source: Arthritis and Rheumatism - December 18, 2013 Category: Rheumatology Authors: Arief Lalmohamed, Peter Vestergaard, Anthonius de Boer, Hubertus G.M. Leufkens, Tjeerd P. van Staa, Frank de Vries Tags: Full Length Source Type: research

Prevalence of comorbidities in rheumatoid arthritis and evaluation of their monitoring: results of an international, cross-sectional study (COMORA)
Conclusions Among RA patients, there is a high prevalence of comorbidities and their risk factors. In this multinational sample, variability among countries was wide, not only in prevalence but also in compliance with recommendations for preventing and managing these comorbidities. Systematic measurement of vital signs and laboratory testing detects otherwise unrecognised comorbid conditions.
Source: Annals of the Rheumatic Diseases - December 4, 2013 Category: Rheumatology Authors: Dougados, M., Soubrier, M., Antunez, A., Balint, P., Balsa, A., Buch, M. H., Casado, G., Detert, J., El-zorkany, B., Emery, P., Hajjaj-Hassouni, N., Harigai, M., Luo, S.-F., Kurucz, R., Maciel, G., Mola, E. M., Montecucco, C. M., McInnes, I., Radner, H., Tags: Open access, Immunology (including allergy), Connective tissue disease, Degenerative joint disease, Musculoskeletal syndromes, Osteoporosis, Rheumatoid arthritis, Epidemiology, Calcium and bone Clinical and epidemiological research Source Type: research

Gout as a risk factor for myocardial infarction and stroke in England: evidence from record linkage studies
Conclusion. Gout was associated with increased risk of stroke as well as MI. These findings should be considered by clinicians and may have implications for preventive management of circulatory disease risks in people with gout.
Source: Rheumatology - November 14, 2013 Category: Rheumatology Authors: Seminog, O. O., Goldacre, M. J. Tags: Crystal Arthritis CLINICAL SCIENCE Source Type: research

Estimated Frequency of Antiphospholipid Antibodies in Patients With Pregnancy Morbidity, Stroke, Myocardial Infarction, and Deep Vein Thrombosis: A Critical Review of the Literature
ConclusionIt is difficult to determine the frequency of a “clinically significant aPL profile” in patients with aPL‐related clinical outcomes due to the lack of robust data. Our best estimates of the incidence of aPL‐associated events should be confirmed with appropriately designed population studies.
Source: Arthritis Care and Research - October 28, 2013 Category: Rheumatology Authors: Laura Andreoli, Cecilia B. Chighizola, Alessandra Banzato, Guillermo J. Pons‐Estel, Guilherme Ramire Jesus, Doruk Erkan, Tags: Brief Reports Source Type: research

Association of Systemic Lupus Erythematosus With a Higher Risk of Cervical but Not Trochanteric Hip Fracture: A Nationwide Population‐Based Study
ConclusionSLE is associated with a higher risk for cervical but not trochanteric HF, and these 2 types of HFs have different risk factors.
Source: Arthritis Care and Research - September 24, 2013 Category: Rheumatology Authors: Shu‐Hung Wang, Yu‐Sheng Chang, Chia‐Jen Liu, Chien‐Chih Lai, Wei‐Sheng Chen, Tzeng‐Ji Chen, Shuu‐Jiun Wang Tags: Systemic Lupus Erythematosus Source Type: research