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Condition: Cardiomyopathy

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Total 1426 results found since Jan 2013.

High-Burden Premature Atrial Contractions Predict New-Onset Atrial Fibrillation After Surgical Septal Myectomy
We examined the correlation between different preoperative PAC burdens and POAF in patients with obstructive hypertrophic cardiomyopathy (OHCM) who underwent surgical treatment. We analyzed 304 consecutively admitted patients with OHCM without previous AF who underwent isolated septal myectomy between January 2015 and December 2018.
Source: The American Journal of Cardiology - May 5, 2023 Category: Cardiology Authors: Yanhai Meng, Changrong Nie, Yanbo Zhang, Changsheng Zhu, Enci Hu, Jigao Shang, Tao Lu, Zining Wu, Shuiyun Wang Source Type: research

The prognostic role of right ventricular dysfunction in patients with hypertrophic cardiomyopathy
AbstractHypertrophic cardiomyopathy (HCM) primarily affects the left ventricle (LV) sparing the right ventricle (RV) in vast majority of cases. However, several studies employing CMR have revealed that myocardial hypertrophy may also involve the RV. To assess RV size and function in a large prospectively cohort of HCM patients and to evaluate whether these parameters in association with other MR findings can predict cardiac events. Two participating centers prospectively included patients with known or suspected HCM between 2011 and 2017. CMR studies were performed with three different scanners. Outcome measures were a com...
Source: The International Journal of Cardiovascular Imaging - May 5, 2023 Category: Radiology Source Type: research

Po-05-185 prediction and risk of atrial fibrillation in patients with hypertrophic cardiomyopathy: a danish nationwide cohort study
Hypertrophic cardiomyopathy (HCM) can be associated with serious complications such as heart failure, atrial fibrillation (AF) and sudden cardiac death. The treatment of AF in HCM patients can be challenging since AF often aggravates symptoms and increases the risk of stroke. Little is known on which factors contribute to the development of AF in these patients.
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: Christopher Z örner, Jannik L. Pallisgaard, Anne-Marie Schjerning, Morten K. Jensen, Jacob Tønnesen, Lise D. Vestergaard, Peter Vibe Rasmussen, Gunnar Gislason, Morten L. Hansen Source Type: research

Po-01-108 elucidating the mechanism of atrial fibrillation in lamin a/c heart disease using human ipsc-derived atrial cardiomyocytes
Mutations in the LMNA gene, encoding the nuclear envelope proteins lamin A/C, cause cardiac arrhythmias, conduction disease, and dilated cardiomyopathy. Malignant arrhythmias such as atrial fibrillation (AF) and ventricular tachycardia are common and pose an increased risk of stroke and sudden cardiac death.
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: William Janes, Asia Owais, Hanna Chen, Yining Chen, Michael Hill, Dawood Darbar, Srinath Yeshwant Source Type: research

Po-05-169 ventricular scar by cardiac mri is a predictor of atrial fibrillation in hypertrophic cardiomyopathy
Atrial fibrillation (AF) in patients with hypertrophic cardiomyopathy (HCM) increases risk of stroke and mortality. The reported prevalence of AF in HCM ranges from 18% to 28%, which is higher than the general population; even after accounting for traditional risk factors including obesity, hypertension, and age. Several factors increase risk of AF in HCM including left atrial size and the presence of ventricular obstruction. However, there is paucity of data correlating ventricular late gadolinium enhancement (LGE) to the incidence of AF in HCM.
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: Joseph Banno, David Fermin, Dana Marsy, Nabin Manandhar Shrestha, Richard McNamara, Jeffrey Decker, Alfred J. Albano, Jose Tan, Laura Franey, Wissam Abdallah, Christopher Madison, Renzo Loyaga Rendon, Nagib T. Chalfoun Source Type: research

Po-05-141 association of interatrial block and the development of atrial fibrillation among patients with hypertrophic cardiomyopathy
Atrial fibrillation (AF) is the most common sustained arrhythmia among those with hypertrophic cardiomyopathy (HCM), affecting 1 in 5 patients. The combination of HCM and AF is associated with an increased risk of stroke, heart failure, and mortality. Interatrial block (IAB) is a distinct electrocardiographic (ECG) pattern describing conduction delay between the right and left atria through Bachmann ’s bundle. IAB has been identified as a predictor of AF across several disease states including congestive heart failure, valvular disease, and cardiac amyloidosis.
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: Abdullah Alissa, Nadia Bokhari, Munther K. Homoud, Ethan Rowin, Martin S. Maron, Christopher Madias Source Type: research

C-reactive protein levels are associated with early cardiac complications or death in patients with acute ischemic stroke: a propensity-matched analysis of a global  federated health from the TriNetX network
AbstractThe role of inflammation in predicting early cardiac complications among stroke patients is unclear. Electronic medical records from TriNetX, a global federated health research network, were used for this retrospective analysis. Patients with ischemic stroke and C-Reactive Protein (CRP) levels measured within 24  h post-stroke were categorized into three groups: (i) <  1 mg/L, (ii)1–3 mg/L and (iii) >  3 mg/L. The primary outcome was a composite outcome of cardiac complications (heart failure (HF), ischemic heart disease, atrial fibrillation (AF), ventricular arrhythmias and Takotsubo cardiomyop...
Source: Internal and Emergency Medicine - April 29, 2023 Category: Emergency Medicine Source Type: research

Clinical and Prognostic Relevance of Cardiac Wasting in Patients With Advanced Cancer
CONCLUSIONS: Low LV mass is associated with poor functional status and increased all-cause mortality in cancer. These findings provide clinical evidence of cardiac wasting-associated cardiomyopathy in cancer.PMID:37076211 | DOI:10.1016/j.jacc.2023.02.039
Source: Cancer Control - April 20, 2023 Category: Cancer & Oncology Authors: Alessia Lena Ursula Wilkenshoff Sara Hadzibegovic Jan Porthun Lukas R ösnick Ann-Kathrin Fr öhlich Tanja Zeller Mahir Karakas Ulrich Keller Johann Ahn Lars Bullinger Hanno Riess Stuart D Rosen Alexander R Lyon Thomas F L üscher Matthias Totzeck Tienush Source Type: research

Hypertrophic Cardiomyopathy and Atrial Fibrillation: A Systematic Review and Meta-analysis of Anticoagulation Strategy
ConclusionsCompared with VKAs, a DOAC-based strategy might represent an effective and safe strategy regarding all-cause mortality, major/life-threatening bleeding complications, and TEs in HCM patients with concomitant AF. However, further prospective studies are necessary to reinforce a DOAC-based anticoagulation strategy in this population.
Source: American Journal of Cardiovascular Drugs - April 15, 2023 Category: Cardiology Source Type: research

Incidence of stroke in patients with hypertrophic cardiomyopathy in stable sinus rhythm during long-term monitoring
Patients with hypertrophic cardiomyopathy (HCM) are at increased risk of stroke, but the incidence and factors associated with cardioembolic events in HCM patients without atrial fibrillation (AF) remain unresolved. We determined the incidence of stroke in patients in sinus rhythm (SR) monitored with a cardiac implantable electronic device (CIED).
Source: International Journal of Cardiology - April 13, 2023 Category: Cardiology Authors: Carlo Fumagalli, Francesca Bonanni, Matteo Beltrami, Roberta Ruggieri, Chiara Zocchi, Luigi Tassetti, Niccol ò Maurizi, Martina Berteotti, Mattia Zampieri, Alessia Argirò, Fabrizio Lovero, Alessia Tomberli, Mauro di Bari, Niccolò Marchionni, Paolo Pier Source Type: research

Inhibition of the pyroptosis-associated inflammasome pathway: The important potential mechanism of ginsenosides in ameliorating diabetes and its complications
Eur J Med Chem. 2023 Apr 5;253:115336. doi: 10.1016/j.ejmech.2023.115336. Online ahead of print.ABSTRACTDiabetes mellitus (DM) and its complications have become an important global public health issue, affecting human health and negatively impacting life and lifespan. Pyroptosis is a recently discovered form of pro-inflammatory programmed cell death (PCD). To date, pyroptosis-associated inflammasome pathways have been identified primarily in the canonical and non-canonical inflammasome pathway, apoptotic caspase-mediated pathway, granzyme-mediated pathway, and streptococcal pyrogenic exotoxin B (SpeB)-mediated pathway. The...
Source: European Journal of Medicinal Chemistry - April 9, 2023 Category: Chemistry Authors: Pan Liu Zhengdong Zhang Yichen Cai Yunjiao Yang Jun Yuan Qiu Chen Source Type: research

Factors influencing left ventricular thrombus resolution and its significance on clinical outcomes
ConclusionsThis study suggests that LVT resolution is an important predictor for favourable clinical outcomes. LVEF improvement failure interfered with LVT resolution and appeared to be a crucial factor for LVT recurrence. After LVT resolution, continuation of anticoagulation did not seem to impact LVT recurrence and the prognosis.
Source: ESC Heart Failure - April 4, 2023 Category: Cardiology Authors: Se ‐Eun Kim, Chan Joo Lee, Jaewon Oh, Seok‐Min Kang Tags: Original Article Source Type: research

Atrial cardiomyopathy and incident ischemic stroke risk: a systematic review and meta-analysis
ConclusionAtrial cardiomyopathy markers, including electrocardiographic markers, serum markers, LA structural and functional markers, can be used to stratify the risk of incident ischemic stroke.
Source: Journal of Neurology - April 4, 2023 Category: Neurology Source Type: research

A case of acute ischemic stroke caused by doxorubicin-induced cardiomyopathy in a patient with synovial sarcoma
Source: Acta Neurologica Belgica - March 30, 2023 Category: Neurology Source Type: research