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Condition: Cardiomyopathy

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Total 1426 results found since Jan 2013.

Hypertrophic cardiomyopathy in adults: An overview
ConclusionsAlthough HCM is the most prevalent genetic disorder affecting the heart, it often goes undiagnosed until midlife after patients show symptoms of myocardial remodeling. Adults with cardiomyopathy suffer SCD or adverse events such as stroke and heart failure from HCM. Early diagnosis will prevent SCD, improve quality of life, and slow patient's progression to heart failure. Implications for practiceEarly recognition of HCM in adults by their primary care providers will improve patients’ quality of life and reduce incidence of SCD, heart failure, and stroke.
Source: Journal of the American Academy of Nurse Practitioners - June 1, 2014 Category: Nursing Authors: Cynthia Jacobs Tags: CE ARTICLE Source Type: research

CNS-disease affecting the heart: Brain–heart disorders
Abstract: There are a number of hereditary and non-hereditary central nervous system (CNS) disorders, which directly or indirectly affect the heart (brain–heart disorders). The most well-known of these CNS-disorders are epilepsy, stroke, subarachanoid bleeding, bacterial meningitis, and head injury. In addition, a number of hereditary and non-hereditary neurodegenerative disorders may impair cardiac functions. Affection of the heart may manifest as arrhythmias, cardiomyopathy, or autonomic dysfunction. Rarer cardiac complications of CNS disorders include heart failure, systolic or diastolic dysfunction, myocardial infarc...
Source: Journal of the Neurological Sciences - July 10, 2014 Category: Neurology Authors: Josef Finsterer, Karim Wahbi Tags: Reviews Source Type: research

Cardiac Magnetic Resonance Imaging Findings Predict Major Adverse Events in Apical Hypertrophic Cardiomyopathy
Conclusions:Within our population of apical HCM patients, the extent of LGE and the presence of an apical aneurysm identified by cardiac MRI were both significant predictors of major adverse clinical events.
Source: Journal of Thoracic Imaging - October 24, 2014 Category: Radiology Tags: Original Articles Source Type: research

Pretransplant and perioperative predictors of early heart transplantation outcomes.
Conclusion. Pretransplant predictors of adverse outcome after heart transplantation were recipient age, lower BMI, ischemic cardiomyopathy, reoperation and diabetes. Postoperative predictors of mortality were inferior donor heart hemodynamics, epinephrine use, and serum lactate concentrations. Non-survivors were more likely to require re-sternotomy, MCS, and RRT. PMID: 25559826 [PubMed - in process]
Source: Croatian Medical Journal - December 31, 2014 Category: Journals (General) Authors: Gašparović H, Ivanković S, Ljubas Maček J, Matovinović F, Nedić M, Svetina L, Čikes M, Skorić B, Baričević Ž, Ivančan V, Biočina B, Miličić D Tags: Croat Med J Source Type: research

Associations of Lifetime Abstention and Past and Current Alcohol Use with Late-Life Mental Health: A Propensity Score Analysis
A recent review of studies that examined health effects of alcohol consumption concludes that habitual light-to-moderate alcohol intake (up to 1 drink per day for women and 1 or 2 drinks per day for men) is associated with lower rates of death, coronary artery disease, congestive heart failure, diabetes mellitus, and stroke (O’Keefe et al., 2014). The review also reports that excessive alcohol intake, in a dose-dependent fashion, commonly causes irreversible hypertension and atrial fibrillation, accounts for one third of all cases of nonischemic dilated cardiomyopathy, and markedly increases risks of both ischemic...
Source: Drug and Alcohol Dependence - February 16, 2015 Category: Addiction Authors: C. Nathan Marti, Namkee G. Choi, Diana M. DiNitto, Bryan Y. Choi Tags: Full length article Source Type: research

Outcomes in Nonagenarians Undergoing Transcatheter Aortic Valve Replacement in the PARTNER-I Trial.
CONCLUSIONS: A TAVR can be performed in nonagenarians with acceptable short- and mid-term outcomes. Although TF- and TA-TAVR outcomes are not directly comparable, TA-TAVR appears to carry a higher risk of early death without a difference in intermediate-term mortality. Age alone should not preclude referral for TAVR in nonagenarians. PMID: 26242213 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - August 1, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Thourani VH, Jensen HA, Babaliaros V, Kodali SK, Rajeswaran J, Ehrlinger J, Blackstone EH, Suri RM, Don CW, Aldea G, Williams MR, Makkar R, Svensson LG, McCabe JM, Dean LS, Kapadia S, Cohen DJ, Pichard AD, Szeto WY, Herrmann HC, Devireddy C, Leshnower BG, Tags: Ann Thorac Surg Source Type: research

Ventricular Tachycardia associated with Mid-Ventricular Obstructive Hypertrophic Cardiomyopathy and Apical Aneurysm
We report a case of a 68-years old man who came to the Emergency Department because of a Stroke preceded by episodes of fainting.
Source: International Journal of Cardiology - August 10, 2015 Category: Cardiology Authors: G. Cannavà, A. Currò Source Type: research

Antiplatelet therapy in Takotsubo cardiomyopathy: does it improve cardiovascular outcomes during index event?
Abstract Plasma catecholamines may play an important role in Takotsubo cardiomyopathy (TCM) pathophysiology. Patients with disproportionately high catecholamine responses to stressful events are prone to worse clinical outcomes. Catecholamines stimulate platelet activation and, therefore, may determine the clinical presentation and outcomes of TCM. We conducted a retrospective, descriptive study TCM patients admitted between 2003 and 2013 to Einstein Medical Center, Philadelphia, PA, USA and Danbury Hospital, Danbury, CT, USA. A total of 206 patients met Modified Mayo TCM criteria. Using a multiple logistic model,...
Source: Heart and Vessels - August 13, 2015 Category: Cardiology Source Type: research

Outcomes in Nonagenarians Undergoing Transcatheter Aortic Valve Replacement in the PARTNER-I Trial
Conclusions A TAVR can be performed in nonagenarians with acceptable short- and mid-term outcomes. Although TF- and TA-TAVR outcomes are not directly comparable, TA-TAVR appears to carry a higher risk of early death without a difference in intermediate-term mortality. Age alone should not preclude referral for TAVR in nonagenarians.
Source: The Annals of Thoracic Surgery - September 1, 2015 Category: Cardiovascular & Thoracic Surgery Source Type: research

Cochrane corner: vitamin K for improved anticoagulation control in patients receiving warfarin
There has been a substantial increase in the use of oral anticoagulants, notably in the ageing population. This is primarily driven by the use of warfarin in people with atrial fibrillation (AF) in order to reduce the risks of thromboembolic events such as stroke.1 In elderly patients with AF, warfarin use has been shown to reduce the relative risk of stroke by >50% compared with aspirin alone.2 Warfarin is also used to treat patients with deep vein thrombosis, mechanical heart valve replacement, cardioversion, cardiomyopathy and antiphospholipid syndrome.1 The clinical benefits of warfarin must also be balanced with po...
Source: Heart - October 11, 2015 Category: Cardiology Authors: Mahtani, K. R., Nunan, D., Heneghan, C. Tags: Drugs: cardiovascular system, Cochrane Corner, Venous thromboembolism, Epidemiology Editorials Source Type: research

Abnormal Left Ventricular Mechanics of Ventricular Ectopic Beats: Insights Into Origin and Coupling Interval in Premature Ventricular Contraction-Induced Cardiomyopathy Original Articles
Conclusions— PVCs with longer coupling intervals demonstrate more pronounced LV dyssynchrony, whereas PVC location has minimal impact. LV dyssynchrony cannot be attributed to prematurity or abnormal ventricular activation alone, but rather to a combination of both. This study suggests that late-coupled PVCs may cause a more severe cardiomyopathy if dyssynchrony is the leading mechanism responsible for PVC-induced cardiomyopathy.
Source: Circulation: Arrhythmia and Electrophysiology - October 20, 2015 Category: Cardiology Authors: Potfay, J., Kaszala, K., Tan, A. Y., Sima, A. P., Gorcsan, J., Ellenbogen, K. A., Huizar, J. F. Tags: Other heart failure, Animal models of human disease, Arrythmias-basic studies, Echocardiography Original Articles Source Type: research

Assessment of Left Ventricular Ejection Fraction Calculation on Long-axis Views From Cardiac Magnetic Resonance Imaging in Patients With Acute Myocardial Infarction
The objective of this study was to assess another method consisting of the evaluation of 2 long-axis slices (CMRLAX) for LVEF determination in acute myocardial infarction. One hundred patients underwent CMR 2 to 4 days after acute myocardial infarction. LVEF was computed by the area-length method on horizontal and vertical CMRLAX images. Those results were compared to reference values obtained on contiguous CMRSAX images in one hand, and to values obtained from transthoracic echocardiography (TTE) in the other hand. For CMRSAX and TTE, LVEF was computed with Simpson method. Reproducibility of LVEF measurements was addition...
Source: Medicine - October 1, 2015 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Prediction of atrial fibrillation development and progression: Current perspectives.
Abstract Atrial fibrillation (AF) is the most common arrhythmia in clinical practice. Several conventional and novel predictors of AF development and progression (from paroxysmal to persistent and permanent types) have been reported. The most important predictor of AF progression is possibly the arrhythmia itself. The electrical, mechanical and structural remodeling determines the perpetuation of AF and the progression from paroxysmal to persistent and permanent forms. Common clinical scores such as the hypertension, age ≥ 75 years, transient ischemic attack or stroke, chronic obstructive pulmonary disease, and ...
Source: World Journal of Cardiology - March 25, 2016 Category: Cardiology Authors: Vlachos K, Letsas KP, Korantzopoulos P, Liu T, Georgopoulos S, Bakalakos A, Karamichalakis N, Xydonas S, Efremidis M, Sideris A Tags: World J Cardiol Source Type: research

'Real-world management and outcomes of patients with paroxysmal vs. non-paroxysmal atrial fibrillation in Europe: the EURObservational Research Programme-Atrial Fibrillation (EORP-AF) General Pilot Registry
Conclusion In this ‘real-world’ contemporary observational registry, patients with non-paroxysmal AF had a worse outcome, in terms of all-cause mortality, which was related to a more severe clinical profile. The risk of stroke at 1 year was relatively low, perhaps reflecting the high rates of anticoagulation use in this cohort.
Source: Europace - May 24, 2016 Category: Cardiology Authors: Boriani, G., Laroche, C., Diemberger, I., Fantecchi, E., Popescu, M. I., Rasmussen, L. H., Dan, G.-A., Kalarus, Z., Tavazzi, L., Maggioni, A. P., Lip, G. Y. H. Tags: Atrial fibrillation Source Type: research

Significance of apical cavity obliteration in apical hypertrophic cardiomyopathy
Conclusions The ratio of obliteration to cavity could provide useful information to predict the occurrence of adverse events in apical HCM.
Source: Heart - July 10, 2016 Category: Cardiology Authors: Kim, H., Park, J.-H., Won, K.-B., Yoon, H.-J., Park, H.-S., Cho, Y.-K., Nam, C.-W., Han, S., Hur, S.-H., Kim, Y.-N., Kim, K.-B. Tags: Hypertrophic cardiomyopathy, Drugs: cardiovascular system, Hypertension, Epidemiology Heart failure and cardiomyopathies Source Type: research