Rare diseases and omics-driven personalized medicine.
ić G PMID: 31894912 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - December 31, 2019 Category: General Medicine Authors: Šimić G Tags: Croat Med J Source Type: research

The prevalence of muscular dystrophy and spinal muscular atrophy in Croatia: data from national and non-governmental organization registries.
CONCLUSION: SMA prevalence rate in Croatia is similar to SMA prevalence worldwide. However, MD prevalence rate is higher than worldwide estimates. This difference could be attributed to the fact that we could not confirm whether every patient registered in these databases actually met the diagnostic criteria for MD and SMA. PMID: 31894913 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - December 31, 2019 Category: General Medicine Authors: Draušnik Ž, Cerovečki I, Štefančić V, Mihel S, Stevanović R, Barišić N, Matković H, Melša M, Mirić M, Pjevač N, Benjak T Tags: Croat Med J Source Type: research

Epidemiological and clinical features of primary biliary cholangitis in two Croatian regions: a retrospective study.
CONCLUSION: This study gives pioneer insights into the epidemiological and clinical data on PBC in Croatia, thus complementing the PBC map of Southeast Europe. PMID: 31894914 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - December 31, 2019 Category: General Medicine Authors: Madir A, Božin T, Mikolašević I, Milić S, Štimac D, Mijić M, Filipec Kanižaj T, Biloglav Z, Lucijanić M, Lucijanić I, Grgurević I Tags: Croat Med J Source Type: research

Silicon foil patching for blast tympanic membrane perforation: a retrospective study.
CONCLUSION: Covering the perforation after the war blast injury with silicon foil significantly improves the rate of tympanic membrane healing. To obtain the best healing outcome, the procedure should be performed within the first 72 hours after the trauma. PMID: 31894915 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - December 31, 2019 Category: General Medicine Authors: Branica S, Dawidowsky K, Kovač-Bilić L, Bilić M Tags: Croat Med J Source Type: research

Maternal body mass index change as a new optimal gestational weight gain predictor in overweight women.
scaron;ek O Abstract AIM: To investigate the relationship between maternal pre-pregnancy body-mass index (BMI) and neonatal birth weight. METHODS: The observational study included 2906 mothers and their neonates born from 2005 to 2011 at the Department of Gynecology and Obstetrics, Split University Hospital Center. Mothers with singleton term pregnancies who were overweight before pregnancy (BMI 25-29.9 kg/m2) were compared with those with normal pre-pregnancy weight (BMI 18.5-24.9 kg/m2). BMI change was assessed as a predictor of birth weight, categorized as small (SGA), appropriate (AGA), or large for gesta...
Source: Croatian Medical Journal - December 31, 2019 Category: General Medicine Authors: Meštrović Z, Roje D, Relja A, Kosović I, Aračić N, Vulić M, Polašek O Tags: Croat Med J Source Type: research

Association of ferritin levels with depression, anxiety, sleep quality, and physical functioning in patients with fibromyalgia syndrome: a cross-sectional study.
Abstract AIM: To determine the frequency of ferritin deficiency in individuals with fibromyalgia syndrome (FMS) and to evaluate the association of ferritin level with depression, anxiety, sleep quality, and physical functioning. METHODS: This cross-sectional study, conducted from 2016 to 2017, compared the frequency of ferritin deficiency between 100 non-anemic fibromyalgia patients and 100 non-anemic individuals without FMS. Serum ferritin level of
Source: Croatian Medical Journal - December 31, 2019 Category: General Medicine Authors: Okan S, Caglıyan Turk A, Sıvgın H, Ozsoy F, Okan F Tags: Croat Med J Source Type: research

Expression and localization of DAB1 and Reelin during normal human kidney development.
CONCLUSION: The appearance of DAB1 and Reelin during fetal kidney development confirms their potential significant role in the formation of kidney structure or function. High DAB1 expression in the DCT implies its regulatory role in tubular formation or function maintenance during development. Reelin was highly expressed in human kidneys at early fetal stages, mostly in the PCT, while at later fetal stages and postnatal period its expression decreased. PMID: 31894918 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - December 31, 2019 Category: General Medicine Authors: Racetin A, Jurić M, Filipović N, Šolić I, Kosović I, Glavina Durdov M, Kunac N, Zekić Tomaš S, Saraga M, Šoljić V, Martinović V, Petričević J, Restović I, Lasić V, Kostić S, Kablar B, Watanabe K, Katsuyama Y, Saraga Babić M, Vukojević K Tags: Croat Med J Source Type: research

Inhibiting alpha subunit of eukaryotic initiation factor 2 dephosphorylation protects injured hepatocytes and reduces hepatocyte proliferation in acute liver injury.
CONCLUSIONS: In acute liver injury, inhibiting eIF2α dephosphorylation protects injured hepatocytes and reduces hepatocyte proliferation. PMID: 31894919 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - December 31, 2019 Category: General Medicine Authors: Chen G, Yang X, He Y, Tang Y, Tian R, Huang W, Chen H, Yang F, Li Y, Lin S Tags: Croat Med J Source Type: research

Kidney transplantation using a colon pouch (Mainz pouch III): a case report.
We present a case of a 32-year-old male patient with orthotopic kidney transplantation performed using a colon pouch (Mainz-pouch III). He was born with severe anomalies including sacral agenesis, anorectal atresia, and hypospadias, which were corrected during childhood. Neurogenic bladder with severe vesicoureteral reflux led to end-stage renal disease. This dysfunctional bladder was unsuitable for kidney transplantation, and a staged approach for future transplantation was chosen. The first step was the creation of urinary diversion. Due to a short appendix, we created a continent, colon pouch (Mainz pouch III). Two year...
Source: Croatian Medical Journal - December 31, 2019 Category: General Medicine Authors: Markić D, Oguić R, Krpina K, Gršković A, Vukelić I, Rački S, Ivančić A, Primc D, Španjol J Tags: Croat Med J Source Type: research

Skin autoimmunity might be associated with increased efficacy of atezolizumab in metastatic urothelial carcinoma: a case report.
We present a case of a 61-year-old man with metastatic urothelial carcinoma of the right ureter and urinary bladder. After gemcitabine/cisplatin as the first-line chemotherapy and surgery, the patient received atezolizumab 1200 mg i.v. q3w. Following the first atezolizumab administration, he noted vitiligo periorally, on his hands, legs, and the scalp. The patient's overall survival (OS) of>26 months and continuing response to atezolizumab treatment is considerably better than median OS in the SAUL study of 8.7 months (IMvigor211-like patients' OS 10.0 months). This case indicates that increased efficacy of atezolizumab...
Source: Croatian Medical Journal - December 31, 2019 Category: General Medicine Authors: Rkman D, Likić R, Bebek M, Gnjidić M, Gamulin M Tags: Croat Med J Source Type: research

Extraperitoneal radical prostatectomy with the Senhance Surgical System robotic platform.
orušić A PMID: 31894922 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - December 31, 2019 Category: General Medicine Authors: Kaštelan Ž, Knežević N, Hudolin T, Kuliš T, Penezić L, Goluža E, Gidaro S, Ćorušić A Tags: Croat Med J Source Type: research

Different training routes to qualify in occupational medicine.
PMID: 31894923 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - December 31, 2019 Category: General Medicine Authors: Cegolon L Tags: Croat Med J Source Type: research

Rare, rarer, it still has not happened.
PMID: 31894924 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - December 31, 2019 Category: General Medicine Authors: Hackenberger BK Tags: Croat Med J Source Type: research

Further thoughts on P.
PMID: 31894925 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - December 31, 2019 Category: General Medicine Authors: Trkulja V, Hrabač P Tags: Croat Med J Source Type: research

Measles outbreak: a warning sign of troubles ahead.
ić G PMID: 31686452 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - October 31, 2019 Category: General Medicine Authors: Kaić B, Tešović G Tags: Croat Med J Source Type: research

A novel percutaneous transhepatic treatment of a benign bile duct stricture - a pilot study.
CONCLUSION: Percutaneous transhepatic corticosteroid injection combined with balloon dilatation could provide an alternative method for the treatment of benign biliary strictures that is effective in the long term and results in positive outcomes. PMID: 31686453 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - October 31, 2019 Category: General Medicine Authors: Huszár O, Szijarto A, Tihanyi T, Harsányi L, Szücs Á Tags: Croat Med J Source Type: research

Serum ferritin levels and irregular use of iron chelators predict liver iron load in patients with major beta thalassemia: a cross-sectional study.
CONCLUSIONS: Higher serum ferritin strongly predicted the severity of cardiac and liver iron load. Irregular use of chelator drugs was associated with a higher risk of cardiac and liver iron load, regardless of the type of chelating agent. PMID: 31686454 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - October 31, 2019 Category: General Medicine Authors: Sobhani S, Rahmani F, Rahmani M, Askari M, Kompani F Tags: Croat Med J Source Type: research

Visual impairment in children with cerebral palsy: Croatian population-based study for birth years 2003-2008.
Bošnjak V Abstract AIM: To evaluate visual impairment (VI) in children with cerebral palsy (CP). METHODS: This population-based study included 419 children from the Surveillance of Cerebral Palsy in Europe (SCPE) C28 RCP-HR - Register of Cerebral Palsy of Croatia born 2003-2008. Vision in children with CP (according to SCPE) was classified as normal or impaired, with the subcategory of severe VI. The proportion of children with VI was assessed in groups with different CP type/subtype, gross and fine motor function, and gestational age (GA). RESULTS: A total of 266 children had some degree of VI (...
Source: Croatian Medical Journal - October 31, 2019 Category: General Medicine Authors: Striber N, Vulin K, Đaković I, Prvčić I, Đuranović V, Cerovski B, Pejić Roško S, Čokolić Petrović D, Martinec S, Dawidowsky B, Mejaški Bošnjak V Tags: Croat Med J Source Type: research

Association of JAG1 gene polymorphism with systemic blood pressure in patients with obstructive sleep apnea: a prospective cohort study.
áč I, Tkáčová R, Joppa P Abstract AIM: To assess the effects of single nucleotide polymorphisms (SNPs) on blood pressure control in patients with obstructive sleep apnea (OSA). METHODS: This prospective observational cohort study, conducted between 2004 and 2014, examined the associations of SNPs of JAG1, GUCY1A3-GUCY1B3, SH2B3, and NPR3-C5orf23 genes with systolic and diastolic blood pressure (SBP, DBP) in 1179 adults evaluated for OSA with overnight polysomnography. Genotyping was performed by unlabeled probe melting analysis. RESULTS: The patients were predominantly male (69.6%,...
Source: Croatian Medical Journal - October 31, 2019 Category: General Medicine Authors: Paraničová I, Habalová V, Klimčáková L, Trojová I, Židzik J, Tkáč I, Tkáčová R, Joppa P Tags: Croat Med J Source Type: research

Efficacy of adalimumab therapy in experimental rat sclerosing encapsulated peritonitis model.
CONCLUSION: Adalimumab can prevent SEP development. PMID: 31686457 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - October 31, 2019 Category: General Medicine Authors: Akgun Y, Bakirdogen S, Kadioglu Kocak MG, Bektas S, Demir C, Akbal E, Elmas S Tags: Croat Med J Source Type: research

Adipose-derived mesenchymal stem cells attenuate ischemic brain injuries in rats by modulating miR-21-3p/MAT2B signaling transduction.
CONCLUSION: This study confirmed the protective effect of ADMSCs against ischemic brain injury exerted by suppressing miR-21-3p level and up-regulating MAT2B level. PMID: 31686458 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - October 31, 2019 Category: General Medicine Authors: Li C, Fei K, Tian F, Gao C, Yang S Tags: Croat Med J Source Type: research

Stress echocardiography for left ventricular diastolic dysfunction detection in patients with non-severe chronic obstructive pulmonary disease: a cross-sectional study.
Abstract AIM: To assess whether the simultaneous performance of exercise stress echocardiography and cardio-pulmonary testing (ESE-CPET) may facilitate the timely diagnosis of subclinical left ventricular diastolic dysfunction (LVDD) in patients with non-severe chronic obstructive pulmonary disease (COPD), preserved left ventricular systolic function, and exertional dyspnea or exercise intolerance. METHODS: This cross-sectional study, conducted between May 2017 and April 2018, involved 104 non-severe COPD patients with exertional dyspnea and preserved ejection fraction who underwent echocardiography before CP...
Source: Croatian Medical Journal - October 31, 2019 Category: General Medicine Authors: Cherneva RV, Gospodinova MV, Denchev SV, Petkov RB, Kostadinov DE, Cherneva ZV Tags: Croat Med J Source Type: research

Autosomal recessive Alport syndrome caused by a novel COL4A4 splice site mutation: a case report.
caron;ić Ljubanović D Abstract Alport syndrome (AS) is a genetically heterogenic, structural disorder of the glomerular basement membrane (GBM) due to the mutation of COL4A3, COL4A4, or COL4A5 genes, which clinically presents as progressive hematuric nephritis with ultrastructural changes of the GBM, high tone sensorineural hearing loss, and ocular lesions. About 15% of AS cases have autosomal mutations of COL4A3 and COL4A4 genes, including homozygous and compound heterozygous mutations. Here, we present a case of a two-year-old boy with autosomal recessive Alport syndrome (ARAS) caused by a novel c.193-2A>C ...
Source: Croatian Medical Journal - October 31, 2019 Category: General Medicine Authors: Šenjug P, Nikuševa Martić T, Šenjug Perica M, Oroz M, Horaček M, Ćuk M, Abdović S, Galešić Ljubanović D Tags: Croat Med J Source Type: research

M for measles, M for math, M for mod ….
M for measles, M for math, M for mod…. Croat Med J. 2019 Oct 31;60(5):463-468 Authors: Hackenberger BK PMID: 31686461 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - October 31, 2019 Category: General Medicine Authors: Hackenberger BK Tags: Croat Med J Source Type: research

So, what about P?
PMID: 31686462 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - October 31, 2019 Category: General Medicine Authors: Trkulja V, Hrabač P Tags: Croat Med J Source Type: research

Toward confirmation of the safety and efficacy of methoxy polyethylene glycol-epoetin beta in anemia treatment in patients on hemodialysis: a Macedonian experience.
PMID: 31686463 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - October 31, 2019 Category: General Medicine Authors: Kacarska-Fotevska I, Volckova N, Ilievska K, Donev D Tags: Croat Med J Source Type: research

Communication as a powerful tool in the treatment of war veterans with chronic posttraumatic stress disorder and chronic pain.
ač N PMID: 31686464 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - October 31, 2019 Category: General Medicine Authors: Pjevač N, Braš M, Đorđević V, Pjevač N Tags: Croat Med J Source Type: research

In reply to Unopposed Estrogen and Endometrial Cancer: Association or Causation?
PMID: 31686465 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - October 31, 2019 Category: General Medicine Authors: Trkulja V, Hrabač P Tags: Croat Med J Source Type: research

A case of successful treatment and separation of conjoined twins in Croatia!
aron; PMID: 31483114 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - August 31, 2019 Category: General Medicine Authors: Grosek Š Tags: Croat Med J Source Type: research

Successful separation of xypho-omphalopagus conjoined twins with extrauterine twin-twin transfusion syndrome: a case report.
This report describes a successful separation of xypho-omphalopagus conjoined twins complicated by unbalanced blood shunting through the porto-systemic anastomoses within the shared liver parenchyma. Significant extrauterine twin-twin transfusion syndrome caused by unbalanced shunting is an extremely rare, and probably under-recognized, hemodynamic complication in conjoined twins necessitating urgent separation. Progressive deterioration with a poor outcome can be prevented if the condition is recognized in a timely manner. PMID: 31483115 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - August 31, 2019 Category: General Medicine Authors: Grizelj R, Sindičić Dessardo N, Bulić K, Luetić T, Mikulić D, Antabak A, Sjekavica I, Alduk AM, Konosić S, Režek Tomašić K, Ćaleta T, Pleško S, Šarić D, Vuković J Tags: Croat Med J Source Type: research

Admission C-reactive protein and outcomes in acute aortic dissection: a systematic review.
CONCLUSION: This systematic review demonstrated a clear association between elevated admission serum CRP levels and increased in-hospital and mid-term mortality risk in AAD. PMID: 31483116 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - August 31, 2019 Category: General Medicine Authors: Vrsalović M, Vrsalović Presečki A Tags: Croat Med J Source Type: research

The influence of general practitioners on access points to health care in a system without gatekeeping: a cross-sectional study in the context of the QUALICOPC project in Austria.
CONCLUSION: Visiting specialists in Austria is quite common, and the simple presence of a GP as a usual source of care is insufficient to regulate pathways within the health care system. This can be particularly difficult for chronic care patients who often require care at different levels of the system and show higher frequency of ED presentations. PMID: 31483117 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - August 31, 2019 Category: General Medicine Authors: Hoffmann K, George A, Van Loenen T, De Maeseneer J, Maier M Tags: Croat Med J Source Type: research

Cardiopulmonary resuscitation performed by trained providers and shorter time to emergency medical team arrival increased patients' survival rates in Istra County, Croatia: a retrospective study.
vić T, Peršec J Abstract AIM: To assess the effect of the time for emergency medical services (EMS) arrival on resuscitation outcome in the transition period of the EMS system in Istra County. METHODS: This retrospective study analyzed the data from 1440 patients resuscitated between 2011 and 2017. The effect of demographic data, period of the year, time for EMS arrival, initial cardiopulmonary resuscitation (CPR) provider, initial cardiac rhythm, and airway management method on CPR outcome was assessed with multivariate logistic regression. RESULTS: Survivors were younger than non-survivors (med...
Source: Croatian Medical Journal - August 31, 2019 Category: General Medicine Authors: Bakran K, Šribar A, Šerić M, Antić-Šego G, Božić MA, Prijić A, Lacković T, Peršec J Tags: Croat Med J Source Type: research

Validation of the new classification criteria for systemic lupus erythematosus on a patient cohort from a national referral center: a retrospective study.
CONCLUSION: Although the SLICC-12 criteria were superior to the ACR-97 and were more sensitive for diagnosing early SLE, their specificity in our population was too low. The sensitivity of the SLICC-12 classification is increased by better defined clinical features within each criterion. Our results contribute to the current initiative for developing new criteria for SLE. PMID: 31483119 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - August 31, 2019 Category: General Medicine Authors: Bakula M, Čikeš N, Anić B Tags: Croat Med J Source Type: research

The efficacy and adverse effects of budesonide in remission induction treatment of autoimmune hepatitis: a retrospective study.
CONCLUSIONS: This study showed no differences in biochemical response between the groups. Lower, although not significantly, rate of adverse effects and lower total number of adverse effects indicate that BUD/AZA may potentially be used as the first-line treatment of choice, especially in patients with obesity, diabetes, resistant hypertension, glaucoma, or osteoporosis. PMID: 31483120 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - August 31, 2019 Category: General Medicine Authors: Binicier OB, Günay S Tags: Croat Med J Source Type: research

Glutamatergic activation of A1 and A2 noradrenergic neurons in the rat brain stem.
CONCLUSION: Our results suggest that noradrenergic neurons are regulated and/or activated by glutamatergic system and that these neurons express functional glutamate receptors. PMID: 31483121 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - August 31, 2019 Category: General Medicine Authors: Gok-Yurtseven D, Kafa IM, Minbay Z, Eyigor O Tags: Croat Med J Source Type: research

Association between rs2303861 polymorphism in CD82 gene and non-alcoholic fatty liver disease: a preliminary case-control study.
CONCLUSION: A variant on CD82 gene and a miR-193b expression dysregulation may have a role in the development and progression of NAFLD and its sequelae. PMID: 31483122 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - August 31, 2019 Category: General Medicine Authors: Habibzadeh P, Honarvar B, Silawi M, Bahramjahan S, Kazemi A, Faghihi MA, Lankarani K Tags: Croat Med J Source Type: research

Tensors all around us.
PMID: 31483123 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - August 31, 2019 Category: General Medicine Authors: Hackenberger BK Tags: Croat Med J Source Type: research

Confidence intervals: what are they to us, medical doctors?
PMID: 31483124 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - August 31, 2019 Category: General Medicine Authors: Trkulja V, Hrabač P Tags: Croat Med J Source Type: research

"Air fresheners" as legal highs.
"Air fresheners" as legal highs. Croat Med J. 2019 Aug 31;60(4):383-384 Authors: Bježančević M, Dodig-Ćurković K, Palić Kramarić R PMID: 31483125 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - August 31, 2019 Category: General Medicine Authors: Bježančević M, Dodig-Ćurković K, Palić Kramarić R Tags: Croat Med J Source Type: research

National Brain Councils - common challenges and regional cooperation.
PMID: 31483126 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - August 31, 2019 Category: General Medicine Authors: Andjus PR Tags: Croat Med J Source Type: research

Gas micronuclei underlying decompression bubbles may explain the influence of oxygen enriched gases during decompression on bubble formation and endothelial function in self-contained underwater breathing apparatus diving.
PMID: 31483127 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - August 31, 2019 Category: General Medicine Authors: Arieli R Tags: Croat Med J Source Type: research

Unopposed estrogen and endometrial cancer: association or causation?
ić S PMID: 31483128 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - August 31, 2019 Category: General Medicine Authors: LaCroix A, Šimunić V, Vukičević S Tags: Croat Med J Source Type: research

Heines DE. Neuroanatomy Atlas in Clinical Context: Structures, Sections, Systems, and Syndromes.
ić G PMID: 31483129 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - August 31, 2019 Category: General Medicine Authors: Šimić G Tags: Croat Med J Source Type: research

Shafarenko M, Tonfighi T, eds. Essential Med Notes 2019. Comprehensive medical reference and review for USMLE II and MCCQE.
PMID: 31483130 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - August 31, 2019 Category: General Medicine Authors: Raguž M Tags: Croat Med J Source Type: research

Into the third decade: eleventh ISABS Conference on Forensic and Anthropological Genetics and Mayo Clinic Lectures in Individualized Medicine.
PMID: 31187945 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - June 13, 2019 Category: General Medicine Authors: Vuk-Pavlović S, Schanfield M, Primorac D Tags: Croat Med J Source Type: research

Multiple genetic analyses to investigate the polymorphisms of Chinese Mongolian population with an efficient short tandem repeat panel.
Abstract AIM: To determine allele frequencies and forensic statistics of 22 autosomal short tandem repeat loci in Chinese Mongolian population. METHODS: Blood specimens were collected from 134 unrelated healthy Mongolian individuals, and 22 short tandem repeat loci were co-amplified and genotyped. Allele frequencies and forensic parameters were calculated, and population genetic differences were analyzed among Mongolian population and other eight Chinese populations: Northern Han, Guangdong Han, Chengdu Han, Xinjiang Hui, Xinjiang Uygur, Hainan Li, Qinghai Tibetan, and Hainan Han. RESULTS: All the loci w...
Source: Croatian Medical Journal - June 13, 2019 Category: General Medicine Authors: Fang Y, Xie T, Lan Q, Jin X, Guo Y, Zhou Y, Yan J, Zhu B Tags: Croat Med J Source Type: research

Optimization of an ex vivo gene transfer to the hamstrings tendons muscle remnants: potential for genetic enhancement of bone healing.
Abstract AIM: To assess whether an adenoviral vector carrying the bone morphogenetic protein genes (Ad.BMP-2) can transduce human muscle tissue and direct it toward osteogenic differentiation within one hour. METHODS: This in vitro study, performed at the Department of Molecular Biology, Faculty of Science, Zagreb from 2012 to 2017, used human muscle tissue samples collected during anterior cruciate ligament reconstructions performed in St Catherine Hospital, Zabok. Samples from 28 patients were transduced with adenoviral vector carrying firefly luciferase cDNA (Ad.luc) by using different doses and times of t...
Source: Croatian Medical Journal - June 13, 2019 Category: General Medicine Authors: Rod E, Matić I, Antunović M, Vetma V, Pavičić I, Hudetz D, Marijanović I, Primorac D, Ivković A Tags: Croat Med J Source Type: research

Population study of thrombophilic markers and pharmacogenetic markers of warfarin prevalence in Bosnia and Herzegovina.
CONCLUSION: This study reports the first extensive population genetic data for thrombophilia and warfarin pharmacogenetic markers in Bosnia and Herzegovina. Allele frequencies of genetic variants are within the general average for European populations, and their presence implies the necessity of introduction of personalized medicine in warfarin-mediated antithrombotic therapy. PMID: 31187948 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - June 13, 2019 Category: General Medicine Authors: Ašić A, Salazar R, Storm N, Doğan S, Höppner W, Marjanović D, Primorac D Tags: Croat Med J Source Type: research

Acetabular osteometric standards for sex estimation in contemporary Croatian population.
CONCLUSION: The acetabular measurements can be used for sex estimation in contemporary Croatian population with high accuracy. PMID: 31187949 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - June 13, 2019 Category: General Medicine Authors: Bubalo P, Baković M, Tkalčić M, Petrovečki V, Mayer D Tags: Croat Med J Source Type: research