The physiology and pathophysiology of cerebrospinal fluid: new evidence
Croat Med J. 2021 Aug 31;62(4):307-309.NO ABSTRACTPMID:34472732 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Marijan Klarica Milan Rado š Miroslav Vuki ć Darko Ore šković Source Type: research

18F-FET and 18F-choline PET-CT in patients with MRI-suspected low-grade gliomas: a pilot study
CONCLUSION: Performing PET-CT in patients with newly diagnosed LGG should be preceded by a selection of an appropriate radiopharmaceutical. 18F-FET seems to be more accurate than 18F-FCH in the LGG diagnosis.PMID:34472733 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Ana Mi šir Krpan Marina Hodoli č Anja Tea Golubi ć Maja Bau čić Jakob Nemir Goran Mrak Marijan Žuvić Dra žen Huić Source Type: research

Clinical application of the RONNA G4 system - preliminary validation of 23 robotic frameless brain biopsies
CONCLUSION: The RONNA G4 robotic system is a safe and accurate tool for brain biopsy, although further research warrants a larger patient sample, comparison with other robotic systems, and a systematic analysis of the entry and target point errors.PMID:34472734 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Domagoj Dlaka Marko Švaco Darko Chudy Bojan Jerbi ć Bojan Šekoranja Filip Šuligoj Josip Vidakovi ć Fadi Almahariq Dominik Romi ć Marina Ragu ž Source Type: research

Biomechanical stability analysis of transpedicular screws combined with sublaminar hook-rod system using the finite element method
CONCLUSION: Stiffness analysis showed comparable stiffness between the tested and proposed stabilization construct. Stress analysis showed luxation tendency of the cranially placed hooks, which would most likely lead to system failure.PMID:34472735 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Kre šimir Saša Đurić Josip Rauker Hrvoje Bari ć Ivan Pa šalić Ivan Domazet Petra Barl Jurica Sori ć Marin Stan čić Source Type: research

Effect of adjunctive lidocaine-based scalp block and laryngotracheal local anesthesia vs general anesthesia only on plasma and cerebrospinal fluid pro-inflammatory cytokine concentrations in patients with cerebral aneurysm: a randomized controlled trial
CONCLUSION: Adjunctive lidocaine-based scalp block and laryngotracheal local anesthesia might attenuate CSF IL-6 concentration increase in patients with brain aneurysm.PMID:34472736 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Marijana Matas Vlatka Soto šek Ana Kozmar Robert Liki ć Goran Mrak B álint Nagy Ante Sekuli ć Source Type: research

Spinal dural arteriovenous fistulas: a report on outcomes in a single-center retrospective cohort treated surgically and/or endovascularly
CONCLUSION: Patients who underwent surgery or endovascular treatment had on average significant clinical recovery, while those who underwent treatment crossover had negligible improvement. The extent of myelopathy seems to be associated with clinical improvement.PMID:34472737 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Miroslav Vuki ć Hrvoje Bari ć David Ozreti ć Ivan Jovanovi ć Zdravka Poljakovi ć Katarina Tudor Kre šimir Saša Đurić Source Type: research

The efficacy of surgical treatment of cerebral arteriovenous malformations in a single academic institution: a case series
CONCLUSION: Microsurgery is an appropriate method of treatment for S-M grade I-III pial AVMs. Microsurgery may be used to treat the majority of small-nidus AVMs with a low mortality and morbidity, when precisely planned and performed by an expert vascular team. The meticulous selection of patients for surgical treatment is crucial.PMID:34472738 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Martin Smrcka Ondrej Navratil Evzen Hovorka Kamil Duris Source Type: research

Laterality of deep white matter hyperintensities correlates with basilar artery bending and vertebral artery dominance
CONCLUSIONS: An unequal vertebral artery flow is an important hemodynamic contributor to basilar bending. Increased basilar artery curvature and increased infratentorial WMH burden may signal inadequate blood flow and predict cerebrovascular events.PMID:34472739 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Laszlo Szalontai Zsofia Jokkel Tamas Horvath Bianka Forgo Ildiko Kalina Pal Maurovich-Horvat Philip L Auyang M Mujeeb Zubair Zsolt Garami David Laszlo Tarnoki Adam Domonkos Tarnoki Source Type: research

The applicability of magnetic resonance imaging classification system (MRICS) for cerebral palsy and its association with perinatal factors and related disabilities in a Croatian population-based sample
CONCLUSION: Brain MRICS-based groups were associated with perinatal risk factors and related disabilities of cerebral palsy, but not with common motor disorders. MRI classification score is a reliable diagnostic tool, which strongly correlates with perinatal factors and related disabilities of cerebral palsy.PMID:34472740 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Sanja Lovri ć Kojundžić Danijela Budimir Mr šić Ivana Jelovina Benjamin Benzon Maja Tomasovi ć Source Type: research

The vicious interplay between disrupted sleep and malignant brain tumors: a narrative review
Croat Med J. 2021 Aug 31;62(4):376-386.ABSTRACTMalignant brain tumors are among the most aggressive human neoplasms. One of the most common and severe symptoms that patients with these malignancies experience is sleep disruption. Disrupted sleep is known to have significant systemic pro-tumor effects, both in patients with other types of cancer and those with malignant brain lesions. We therefore provide a review of the current knowledge on disrupted sleep in malignant diseases, with an emphasis on malignant brain tumors. More specifically, we review the known ways in which disrupted sleep enables further malignant progres...
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Darko Ore šković An đelo Kaštelančić Marina Ragu ž Domagoj Dlaka Nina Predrijevac Dinko Matec Martina Matec Damir Tomac Vjekoslav Jele č Tonko Marinovi ć Darko Chudy Source Type: research

Differentiating comorbidities and predicting prognosis in idiopathic normal pressure hydrocephalus using cerebrospinal fluid biomarkers: a review
Croat Med J. 2021 Aug 31;62(4):387-398.ABSTRACTIdiopathic normal pressure hydrocephalus (iNPH) is a condition resulting from impaired cerebrospinal fluid (CSF) absorption and excretion characterized by a triad of symptoms comprising dementia, gait disturbance (impaired trunk balance), and urinary incontinence. CSF biomarkers not only assist in diagnosis but are also important for analyzing the pathology and understanding appropriate treatment indications. As the neuropathological findings characteristic of iNPH have yet to be defined, there remains no method to diagnose iNPH with 100% sensitivity and specificity. Neurotoxi...
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Madoka Nakajima Kaito Kawamura Chihiro Akiba Koichiro Sakamoto Hambing Xu Chihiro Kamohara Ikuko Ogino Kostadin Karagiozov Yuichi Tange Kazuaki Shimoji Shinya Yamada Akihide Kondo Hajime Arai Masakazu Miyajima Source Type: research

Cerebrospinal fluid dynamics
Croat Med J. 2021 Aug 31;62(4):399-410.ABSTRACTThe classical cerebrospinal fluid (CSF) circulation theory has been accepted as an established theory of CSF physiology. It describes bulk CSF flow from production site to absorption site. However, much controversy remains regarding the basic CSF physiology and the mechanisms behind the development of hydrocephalus. In the recent observations made using advanced magnetic resonance imaging (MRI) technique, namely, the time spatial inversion pulse (Time-SLIP) method, CSF was used as internal CSF tracer to trace true CSF movement. Observation of the CSF dynamics using this method...
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Shinya Yamada Source Type: research

The role of mesencephalic aqueduct obstruction in hydrocephalus development: a case report
We report on three patients with mesencephalic aqueduct obstruction, which completely blocked the cerebrospinal fluid communication between the third and fourth cerebral ventricle, demonstrated by standard and high-resolution magnetic resonance sequences. Only one patient developed radiological and clinical presentation of hydrocephalus, without radiological signs of increased intraventricular pressure. The remaining two patients did not show clinical signs of hydrocephalus and had a normal radiological presentation of the ventricular system. These findings contradict the classical concept of cerebrospinal fluid physiology...
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Milan Rado š Darko Ore šković Marijan Klarica Source Type: research

A contribution to the understanding of ocular and cerebrospinal fluid dynamics in astronauts during long-lasting spaceflight
Croat Med J. 2021 Aug 31;62(4):420-421.NO ABSTRACTPMID:34472745 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Darko Ore šković Milan Rado š Marijan Klarica Source Type: research

We can reject a zombie apocalypse
Croat Med J. 2021 Aug 31;62(4):422-424.NO ABSTRACTPMID:34472746 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Charles H Calisher Source Type: research

The physiology and pathophysiology of cerebrospinal fluid: new evidence
Croat Med J. 2021 Aug 31;62(4):307-309.NO ABSTRACTPMID:34472732 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Marijan Klarica Milan Rado š Miroslav Vuki ć Darko Ore šković Source Type: research

18F-FET and 18F-choline PET-CT in patients with MRI-suspected low-grade gliomas: a pilot study
CONCLUSION: Performing PET-CT in patients with newly diagnosed LGG should be preceded by a selection of an appropriate radiopharmaceutical. 18F-FET seems to be more accurate than 18F-FCH in the LGG diagnosis.PMID:34472733 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Ana Mi šir Krpan Marina Hodoli č Anja Tea Golubi ć Maja Bau čić Jakob Nemir Goran Mrak Marijan Žuvić Dra žen Huić Source Type: research

Clinical application of the RONNA G4 system - preliminary validation of 23 robotic frameless brain biopsies
CONCLUSION: The RONNA G4 robotic system is a safe and accurate tool for brain biopsy, although further research warrants a larger patient sample, comparison with other robotic systems, and a systematic analysis of the entry and target point errors.PMID:34472734 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Domagoj Dlaka Marko Švaco Darko Chudy Bojan Jerbi ć Bojan Šekoranja Filip Šuligoj Josip Vidakovi ć Fadi Almahariq Dominik Romi ć Marina Ragu ž Source Type: research

Biomechanical stability analysis of transpedicular screws combined with sublaminar hook-rod system using the finite element method
CONCLUSION: Stiffness analysis showed comparable stiffness between the tested and proposed stabilization construct. Stress analysis showed luxation tendency of the cranially placed hooks, which would most likely lead to system failure.PMID:34472735 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Kre šimir Saša Đurić Josip Rauker Hrvoje Bari ć Ivan Pa šalić Ivan Domazet Petra Barl Jurica Sori ć Marin Stan čić Source Type: research

Effect of adjunctive lidocaine-based scalp block and laryngotracheal local anesthesia vs general anesthesia only on plasma and cerebrospinal fluid pro-inflammatory cytokine concentrations in patients with cerebral aneurysm: a randomized controlled trial
CONCLUSION: Adjunctive lidocaine-based scalp block and laryngotracheal local anesthesia might attenuate CSF IL-6 concentration increase in patients with brain aneurysm.PMID:34472736 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Marijana Matas Vlatka Soto šek Ana Kozmar Robert Liki ć Goran Mrak B álint Nagy Ante Sekuli ć Source Type: research

Spinal dural arteriovenous fistulas: a report on outcomes in a single-center retrospective cohort treated surgically and/or endovascularly
CONCLUSION: Patients who underwent surgery or endovascular treatment had on average significant clinical recovery, while those who underwent treatment crossover had negligible improvement. The extent of myelopathy seems to be associated with clinical improvement.PMID:34472737 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Miroslav Vuki ć Hrvoje Bari ć David Ozreti ć Ivan Jovanovi ć Zdravka Poljakovi ć Katarina Tudor Kre šimir Saša Đurić Source Type: research

The efficacy of surgical treatment of cerebral arteriovenous malformations in a single academic institution: a case series
CONCLUSION: Microsurgery is an appropriate method of treatment for S-M grade I-III pial AVMs. Microsurgery may be used to treat the majority of small-nidus AVMs with a low mortality and morbidity, when precisely planned and performed by an expert vascular team. The meticulous selection of patients for surgical treatment is crucial.PMID:34472738 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Martin Smrcka Ondrej Navratil Evzen Hovorka Kamil Duris Source Type: research

Laterality of deep white matter hyperintensities correlates with basilar artery bending and vertebral artery dominance
CONCLUSIONS: An unequal vertebral artery flow is an important hemodynamic contributor to basilar bending. Increased basilar artery curvature and increased infratentorial WMH burden may signal inadequate blood flow and predict cerebrovascular events.PMID:34472739 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Laszlo Szalontai Zsofia Jokkel Tamas Horvath Bianka Forgo Ildiko Kalina Pal Maurovich-Horvat Philip L Auyang M Mujeeb Zubair Zsolt Garami David Laszlo Tarnoki Adam Domonkos Tarnoki Source Type: research

The applicability of magnetic resonance imaging classification system (MRICS) for cerebral palsy and its association with perinatal factors and related disabilities in a Croatian population-based sample
CONCLUSION: Brain MRICS-based groups were associated with perinatal risk factors and related disabilities of cerebral palsy, but not with common motor disorders. MRI classification score is a reliable diagnostic tool, which strongly correlates with perinatal factors and related disabilities of cerebral palsy.PMID:34472740 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Sanja Lovri ć Kojundžić Danijela Budimir Mr šić Ivana Jelovina Benjamin Benzon Maja Tomasovi ć Source Type: research

The vicious interplay between disrupted sleep and malignant brain tumors: a narrative review
Croat Med J. 2021 Aug 31;62(4):376-386.ABSTRACTMalignant brain tumors are among the most aggressive human neoplasms. One of the most common and severe symptoms that patients with these malignancies experience is sleep disruption. Disrupted sleep is known to have significant systemic pro-tumor effects, both in patients with other types of cancer and those with malignant brain lesions. We therefore provide a review of the current knowledge on disrupted sleep in malignant diseases, with an emphasis on malignant brain tumors. More specifically, we review the known ways in which disrupted sleep enables further malignant progres...
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Darko Ore šković An đelo Kaštelančić Marina Ragu ž Domagoj Dlaka Nina Predrijevac Dinko Matec Martina Matec Damir Tomac Vjekoslav Jele č Tonko Marinovi ć Darko Chudy Source Type: research

Differentiating comorbidities and predicting prognosis in idiopathic normal pressure hydrocephalus using cerebrospinal fluid biomarkers: a review
Croat Med J. 2021 Aug 31;62(4):387-398.ABSTRACTIdiopathic normal pressure hydrocephalus (iNPH) is a condition resulting from impaired cerebrospinal fluid (CSF) absorption and excretion characterized by a triad of symptoms comprising dementia, gait disturbance (impaired trunk balance), and urinary incontinence. CSF biomarkers not only assist in diagnosis but are also important for analyzing the pathology and understanding appropriate treatment indications. As the neuropathological findings characteristic of iNPH have yet to be defined, there remains no method to diagnose iNPH with 100% sensitivity and specificity. Neurotoxi...
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Madoka Nakajima Kaito Kawamura Chihiro Akiba Koichiro Sakamoto Hambing Xu Chihiro Kamohara Ikuko Ogino Kostadin Karagiozov Yuichi Tange Kazuaki Shimoji Shinya Yamada Akihide Kondo Hajime Arai Masakazu Miyajima Source Type: research

Cerebrospinal fluid dynamics
Croat Med J. 2021 Aug 31;62(4):399-410.ABSTRACTThe classical cerebrospinal fluid (CSF) circulation theory has been accepted as an established theory of CSF physiology. It describes bulk CSF flow from production site to absorption site. However, much controversy remains regarding the basic CSF physiology and the mechanisms behind the development of hydrocephalus. In the recent observations made using advanced magnetic resonance imaging (MRI) technique, namely, the time spatial inversion pulse (Time-SLIP) method, CSF was used as internal CSF tracer to trace true CSF movement. Observation of the CSF dynamics using this method...
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Shinya Yamada Source Type: research

The role of mesencephalic aqueduct obstruction in hydrocephalus development: a case report
We report on three patients with mesencephalic aqueduct obstruction, which completely blocked the cerebrospinal fluid communication between the third and fourth cerebral ventricle, demonstrated by standard and high-resolution magnetic resonance sequences. Only one patient developed radiological and clinical presentation of hydrocephalus, without radiological signs of increased intraventricular pressure. The remaining two patients did not show clinical signs of hydrocephalus and had a normal radiological presentation of the ventricular system. These findings contradict the classical concept of cerebrospinal fluid physiology...
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Milan Rado š Darko Ore šković Marijan Klarica Source Type: research

A contribution to the understanding of ocular and cerebrospinal fluid dynamics in astronauts during long-lasting spaceflight
Croat Med J. 2021 Aug 31;62(4):420-421.NO ABSTRACTPMID:34472745 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Darko Ore šković Milan Rado š Marijan Klarica Source Type: research

We can reject a zombie apocalypse
Croat Med J. 2021 Aug 31;62(4):422-424.NO ABSTRACTPMID:34472746 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Charles H Calisher Source Type: research

The physiology and pathophysiology of cerebrospinal fluid: new evidence
Croat Med J. 2021 Aug 31;62(4):307-309.NO ABSTRACTPMID:34472732 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Marijan Klarica Milan Rado š Miroslav Vuki ć Darko Ore šković Source Type: research

18F-FET and 18F-choline PET-CT in patients with MRI-suspected low-grade gliomas: a pilot study
CONCLUSION: Performing PET-CT in patients with newly diagnosed LGG should be preceded by a selection of an appropriate radiopharmaceutical. 18F-FET seems to be more accurate than 18F-FCH in the LGG diagnosis.PMID:34472733 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Ana Mi šir Krpan Marina Hodoli č Anja Tea Golubi ć Maja Bau čić Jakob Nemir Goran Mrak Marijan Žuvić Dra žen Huić Source Type: research

Clinical application of the RONNA G4 system - preliminary validation of 23 robotic frameless brain biopsies
CONCLUSION: The RONNA G4 robotic system is a safe and accurate tool for brain biopsy, although further research warrants a larger patient sample, comparison with other robotic systems, and a systematic analysis of the entry and target point errors.PMID:34472734 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Domagoj Dlaka Marko Švaco Darko Chudy Bojan Jerbi ć Bojan Šekoranja Filip Šuligoj Josip Vidakovi ć Fadi Almahariq Dominik Romi ć Marina Ragu ž Source Type: research

Biomechanical stability analysis of transpedicular screws combined with sublaminar hook-rod system using the finite element method
CONCLUSION: Stiffness analysis showed comparable stiffness between the tested and proposed stabilization construct. Stress analysis showed luxation tendency of the cranially placed hooks, which would most likely lead to system failure.PMID:34472735 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Kre šimir Saša Đurić Josip Rauker Hrvoje Bari ć Ivan Pa šalić Ivan Domazet Petra Barl Jurica Sori ć Marin Stan čić Source Type: research

Effect of adjunctive lidocaine-based scalp block and laryngotracheal local anesthesia vs general anesthesia only on plasma and cerebrospinal fluid pro-inflammatory cytokine concentrations in patients with cerebral aneurysm: a randomized controlled trial
CONCLUSION: Adjunctive lidocaine-based scalp block and laryngotracheal local anesthesia might attenuate CSF IL-6 concentration increase in patients with brain aneurysm.PMID:34472736 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Marijana Matas Vlatka Soto šek Ana Kozmar Robert Liki ć Goran Mrak B álint Nagy Ante Sekuli ć Source Type: research

Spinal dural arteriovenous fistulas: a report on outcomes in a single-center retrospective cohort treated surgically and/or endovascularly
CONCLUSION: Patients who underwent surgery or endovascular treatment had on average significant clinical recovery, while those who underwent treatment crossover had negligible improvement. The extent of myelopathy seems to be associated with clinical improvement.PMID:34472737 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Miroslav Vuki ć Hrvoje Bari ć David Ozreti ć Ivan Jovanovi ć Zdravka Poljakovi ć Katarina Tudor Kre šimir Saša Đurić Source Type: research

The efficacy of surgical treatment of cerebral arteriovenous malformations in a single academic institution: a case series
CONCLUSION: Microsurgery is an appropriate method of treatment for S-M grade I-III pial AVMs. Microsurgery may be used to treat the majority of small-nidus AVMs with a low mortality and morbidity, when precisely planned and performed by an expert vascular team. The meticulous selection of patients for surgical treatment is crucial.PMID:34472738 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Martin Smrcka Ondrej Navratil Evzen Hovorka Kamil Duris Source Type: research

Laterality of deep white matter hyperintensities correlates with basilar artery bending and vertebral artery dominance
CONCLUSIONS: An unequal vertebral artery flow is an important hemodynamic contributor to basilar bending. Increased basilar artery curvature and increased infratentorial WMH burden may signal inadequate blood flow and predict cerebrovascular events.PMID:34472739 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Laszlo Szalontai Zsofia Jokkel Tamas Horvath Bianka Forgo Ildiko Kalina Pal Maurovich-Horvat Philip L Auyang M Mujeeb Zubair Zsolt Garami David Laszlo Tarnoki Adam Domonkos Tarnoki Source Type: research

The applicability of magnetic resonance imaging classification system (MRICS) for cerebral palsy and its association with perinatal factors and related disabilities in a Croatian population-based sample
CONCLUSION: Brain MRICS-based groups were associated with perinatal risk factors and related disabilities of cerebral palsy, but not with common motor disorders. MRI classification score is a reliable diagnostic tool, which strongly correlates with perinatal factors and related disabilities of cerebral palsy.PMID:34472740 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Sanja Lovri ć Kojundžić Danijela Budimir Mr šić Ivana Jelovina Benjamin Benzon Maja Tomasovi ć Source Type: research

The vicious interplay between disrupted sleep and malignant brain tumors: a narrative review
Croat Med J. 2021 Aug 31;62(4):376-386.ABSTRACTMalignant brain tumors are among the most aggressive human neoplasms. One of the most common and severe symptoms that patients with these malignancies experience is sleep disruption. Disrupted sleep is known to have significant systemic pro-tumor effects, both in patients with other types of cancer and those with malignant brain lesions. We therefore provide a review of the current knowledge on disrupted sleep in malignant diseases, with an emphasis on malignant brain tumors. More specifically, we review the known ways in which disrupted sleep enables further malignant progres...
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Darko Ore šković An đelo Kaštelančić Marina Ragu ž Domagoj Dlaka Nina Predrijevac Dinko Matec Martina Matec Damir Tomac Vjekoslav Jele č Tonko Marinovi ć Darko Chudy Source Type: research

Differentiating comorbidities and predicting prognosis in idiopathic normal pressure hydrocephalus using cerebrospinal fluid biomarkers: a review
Croat Med J. 2021 Aug 31;62(4):387-398.ABSTRACTIdiopathic normal pressure hydrocephalus (iNPH) is a condition resulting from impaired cerebrospinal fluid (CSF) absorption and excretion characterized by a triad of symptoms comprising dementia, gait disturbance (impaired trunk balance), and urinary incontinence. CSF biomarkers not only assist in diagnosis but are also important for analyzing the pathology and understanding appropriate treatment indications. As the neuropathological findings characteristic of iNPH have yet to be defined, there remains no method to diagnose iNPH with 100% sensitivity and specificity. Neurotoxi...
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Madoka Nakajima Kaito Kawamura Chihiro Akiba Koichiro Sakamoto Hambing Xu Chihiro Kamohara Ikuko Ogino Kostadin Karagiozov Yuichi Tange Kazuaki Shimoji Shinya Yamada Akihide Kondo Hajime Arai Masakazu Miyajima Source Type: research

Cerebrospinal fluid dynamics
Croat Med J. 2021 Aug 31;62(4):399-410.ABSTRACTThe classical cerebrospinal fluid (CSF) circulation theory has been accepted as an established theory of CSF physiology. It describes bulk CSF flow from production site to absorption site. However, much controversy remains regarding the basic CSF physiology and the mechanisms behind the development of hydrocephalus. In the recent observations made using advanced magnetic resonance imaging (MRI) technique, namely, the time spatial inversion pulse (Time-SLIP) method, CSF was used as internal CSF tracer to trace true CSF movement. Observation of the CSF dynamics using this method...
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Shinya Yamada Source Type: research

The role of mesencephalic aqueduct obstruction in hydrocephalus development: a case report
We report on three patients with mesencephalic aqueduct obstruction, which completely blocked the cerebrospinal fluid communication between the third and fourth cerebral ventricle, demonstrated by standard and high-resolution magnetic resonance sequences. Only one patient developed radiological and clinical presentation of hydrocephalus, without radiological signs of increased intraventricular pressure. The remaining two patients did not show clinical signs of hydrocephalus and had a normal radiological presentation of the ventricular system. These findings contradict the classical concept of cerebrospinal fluid physiology...
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Milan Rado š Darko Ore šković Marijan Klarica Source Type: research

A contribution to the understanding of ocular and cerebrospinal fluid dynamics in astronauts during long-lasting spaceflight
Croat Med J. 2021 Aug 31;62(4):420-421.NO ABSTRACTPMID:34472745 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Darko Ore šković Milan Rado š Marijan Klarica Source Type: research

We can reject a zombie apocalypse
Croat Med J. 2021 Aug 31;62(4):422-424.NO ABSTRACTPMID:34472746 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Charles H Calisher Source Type: research

The physiology and pathophysiology of cerebrospinal fluid: new evidence
Croat Med J. 2021 Aug 31;62(4):307-309.NO ABSTRACTPMID:34472732 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Marijan Klarica Milan Rado š Miroslav Vuki ć Darko Ore šković Source Type: research

18F-FET and 18F-choline PET-CT in patients with MRI-suspected low-grade gliomas: a pilot study
CONCLUSION: Performing PET-CT in patients with newly diagnosed LGG should be preceded by a selection of an appropriate radiopharmaceutical. 18F-FET seems to be more accurate than 18F-FCH in the LGG diagnosis.PMID:34472733 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Ana Mi šir Krpan Marina Hodoli č Anja Tea Golubi ć Maja Bau čić Jakob Nemir Goran Mrak Marijan Žuvić Dra žen Huić Source Type: research

Clinical application of the RONNA G4 system - preliminary validation of 23 robotic frameless brain biopsies
CONCLUSION: The RONNA G4 robotic system is a safe and accurate tool for brain biopsy, although further research warrants a larger patient sample, comparison with other robotic systems, and a systematic analysis of the entry and target point errors.PMID:34472734 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Domagoj Dlaka Marko Švaco Darko Chudy Bojan Jerbi ć Bojan Šekoranja Filip Šuligoj Josip Vidakovi ć Fadi Almahariq Dominik Romi ć Marina Ragu ž Source Type: research

Biomechanical stability analysis of transpedicular screws combined with sublaminar hook-rod system using the finite element method
CONCLUSION: Stiffness analysis showed comparable stiffness between the tested and proposed stabilization construct. Stress analysis showed luxation tendency of the cranially placed hooks, which would most likely lead to system failure.PMID:34472735 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Kre šimir Saša Đurić Josip Rauker Hrvoje Bari ć Ivan Pa šalić Ivan Domazet Petra Barl Jurica Sori ć Marin Stan čić Source Type: research

Effect of adjunctive lidocaine-based scalp block and laryngotracheal local anesthesia vs general anesthesia only on plasma and cerebrospinal fluid pro-inflammatory cytokine concentrations in patients with cerebral aneurysm: a randomized controlled trial
CONCLUSION: Adjunctive lidocaine-based scalp block and laryngotracheal local anesthesia might attenuate CSF IL-6 concentration increase in patients with brain aneurysm.PMID:34472736 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 2, 2021 Category: General Medicine Authors: Marijana Matas Vlatka Soto šek Ana Kozmar Robert Liki ć Goran Mrak B álint Nagy Ante Sekuli ć Source Type: research